STRINGSTRING
pckA pckA ppc ppc A7J50_2326 A7J50_2326 A7J50_2345 A7J50_2345 A7J50_2417 A7J50_2417 A7J50_2678 A7J50_2678 A7J50_2850 A7J50_2850 A7J50_3413 A7J50_3413 lldD lldD A7J50_4718 A7J50_4718 A7J50_5805 A7J50_5805 A7J50_5806 A7J50_5806
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (881 aa)
A7J50_2326Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (895 aa)
A7J50_2345Pfam:pfam01070 FMN-dependent dehydrogenase. (386 aa)
A7J50_2417Pyruvate dehydrogenase; Pfam:pfam02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Belongs to the TPP enzyme family. (574 aa)
A7J50_2678Pfam:pfam00171 Aldehyde dehydrogenase family. (474 aa)
A7J50_2850Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily. (289 aa)
A7J50_3413Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (329 aa)
lldDL-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. (380 aa)
A7J50_4718Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (483 aa)
A7J50_5805Pfam:pfam02436 Conserved carboxylase domain. (602 aa)
A7J50_5806Biotin carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (471 aa)
Your Current Organism:
Pseudomonas antarctica
NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.