node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A7J50_0112 | A7J50_0448 | A7J50_0112 | A7J50_0448 | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.911 |
A7J50_0112 | A7J50_0768 | A7J50_0112 | A7J50_0768 | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.944 |
A7J50_0112 | A7J50_2979 | A7J50_0112 | A7J50_2979 | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | Pfam:pfam00501 AMP-binding enzyme. | 0.928 |
A7J50_0112 | ackA | A7J50_0112 | A7J50_2950 | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.918 |
A7J50_0112 | acsA | A7J50_0112 | A7J50_4528 | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.928 |
A7J50_0112 | acsA-2 | A7J50_0112 | A7J50_4991 | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.928 |
A7J50_0448 | A7J50_0112 | A7J50_0448 | A7J50_0112 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | 0.911 |
A7J50_0448 | A7J50_0768 | A7J50_0448 | A7J50_0768 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.960 |
A7J50_0448 | A7J50_2979 | A7J50_0448 | A7J50_2979 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pfam:pfam00501 AMP-binding enzyme. | 0.908 |
A7J50_0448 | acsA | A7J50_0448 | A7J50_4528 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.908 |
A7J50_0448 | acsA-2 | A7J50_0448 | A7J50_4991 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.908 |
A7J50_0768 | A7J50_0112 | A7J50_0768 | A7J50_0112 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | 0.944 |
A7J50_0768 | A7J50_0448 | A7J50_0768 | A7J50_0448 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.960 |
A7J50_0768 | A7J50_2390 | A7J50_0768 | A7J50_2390 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Putative acetoacetyl-coenzyme A synthetase; Pfam:pfam00501 AMP-binding enzyme. | 0.481 |
A7J50_0768 | A7J50_2979 | A7J50_0768 | A7J50_2979 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Pfam:pfam00501 AMP-binding enzyme. | 0.945 |
A7J50_0768 | A7J50_5694 | A7J50_0768 | A7J50_5694 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. | 0.468 |
A7J50_0768 | ackA | A7J50_0768 | A7J50_2950 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.998 |
A7J50_0768 | acsA | A7J50_0768 | A7J50_4528 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.945 |
A7J50_0768 | acsA-2 | A7J50_0768 | A7J50_4991 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.945 |
A7J50_2390 | A7J50_0768 | A7J50_2390 | A7J50_0768 | Putative acetoacetyl-coenzyme A synthetase; Pfam:pfam00501 AMP-binding enzyme. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.481 |