25 items (Pseudomonas antarctica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A7J50_2060	Antibiotic biosynthesis monooxygenase. (121 aa)
	A7J50_0112	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. (497 aa)
	A7J50_0117	Pfam:pfam02771 Acyl-CoA dehydrogenase, N-terminal domain. (393 aa)
	A7J50_0448	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa)
	A7J50_0599	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa)
	A7J50_0768	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (699 aa)
	accA	acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
	A7J50_1570	Urea carboxylase; Pfam:pfam02626 Allophanate hydrolase subunit 2. (1230 aa)
	A7J50_1837	Putative acyl-CoA thioesterase II; Pfam:pfam13622 Thioesterase-like superfamily. (265 aa)
	A7J50_2390	Putative acetoacetyl-coenzyme A synthetase; Pfam:pfam00501 AMP-binding enzyme. (652 aa)
	ackA	Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)
	A7J50_2979	Pfam:pfam00501 AMP-binding enzyme. (549 aa)
	A7J50_2995	Pfam:pfam13302 Acetyltransferase (GNAT) domain. (170 aa)
	accD	acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa)
	A7J50_4021	Hypothetical protein; Pfam:pfam12681 Glyoxalase-like domain. (127 aa)
	acsA	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
	A7J50_4777	Pfam:pfam03061 Thioesterase superfamily. (137 aa)
	acsA-2	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
	A7J50_5089	Pfam:pfam13622 Thioesterase-like superfamily. (289 aa)
	A7J50_5445	Thioesterase; Pfam:pfam03061 Thioesterase superfamily. (134 aa)
	A7J50_5470	Malonate decarboxylase subunit beta; Pfam:pfam01039 Carboxyl transferase domain. (280 aa)
	A7J50_5694	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. (640 aa)
	A7J50_5786	Long-chain acyl-CoA thioester hydrolase; Pfam:pfam03061 Thioesterase superfamily. (134 aa)
	A7J50_5806	Biotin carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (471 aa)
	A7J50_5815	Pfam:pfam03061 Thioesterase superfamily. (161 aa)

Your Current Organism:

Pseudomonas antarctica

NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A7J50_0112	A7J50_0448	A7J50_0112	A7J50_0448	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.911
A7J50_0112	A7J50_0599	A7J50_0112	A7J50_0599	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.902
A7J50_0112	A7J50_0768	A7J50_0112	A7J50_0768	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.944
A7J50_0112	A7J50_2979	A7J50_0112	A7J50_2979	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	Pfam:pfam00501 AMP-binding enzyme.	0.928
A7J50_0112	accA	A7J50_0112	A7J50_1423	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.900
A7J50_0112	accD	A7J50_0112	A7J50_3868	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.900
A7J50_0112	ackA	A7J50_0112	A7J50_2950	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.918
A7J50_0112	acsA	A7J50_0112	A7J50_4528	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.928
A7J50_0112	acsA-2	A7J50_0112	A7J50_4991	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.928
A7J50_0448	A7J50_0112	A7J50_0448	A7J50_0112	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	0.911
A7J50_0448	A7J50_0599	A7J50_0448	A7J50_0599	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.908
A7J50_0448	A7J50_0768	A7J50_0448	A7J50_0768	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.960
A7J50_0448	A7J50_2979	A7J50_0448	A7J50_2979	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pfam:pfam00501 AMP-binding enzyme.	0.908
A7J50_0448	A7J50_5806	A7J50_0448	A7J50_5806	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Biotin carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain.	0.819
A7J50_0448	accA	A7J50_0448	A7J50_1423	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.903
A7J50_0448	accD	A7J50_0448	A7J50_3868	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.904
A7J50_0448	acsA	A7J50_0448	A7J50_4528	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.908
A7J50_0448	acsA-2	A7J50_0448	A7J50_4991	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.908
A7J50_0599	A7J50_0112	A7J50_0599	A7J50_0112	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain.	0.902
A7J50_0599	A7J50_0448	A7J50_0599	A7J50_0448	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.908