STRINGSTRING
aroE aroE A7J50_0052 A7J50_0052 A7J50_0053 A7J50_0053 A7J50_0054 A7J50_0054 A7J50_0394 A7J50_0394 A7J50_0636 A7J50_0636 A7J50_0653 A7J50_0653 hisD hisD mqo mqo A7J50_0921 A7J50_0921 A7J50_0967 A7J50_0967 A7J50_0992 A7J50_0992 A7J50_1088 A7J50_1088 A7J50_1138 A7J50_1138 dxr dxr A7J50_1431 A7J50_1431 A7J50_1542 A7J50_1542 A7J50_1641 A7J50_1641 pdxB pdxB fadB fadB mqo-2 mqo-2 A7J50_1858 A7J50_1858 A7J50_1930 A7J50_1930 gpsA gpsA A7J50_2131 A7J50_2131 A7J50_2162 A7J50_2162 A7J50_2233 A7J50_2233 A7J50_2276 A7J50_2276 A7J50_2345 A7J50_2345 A7J50_2369 A7J50_2369 A7J50_2391 A7J50_2391 iolG iolG A7J50_2579 A7J50_2579 A7J50_2583 A7J50_2583 A7J50_2618 A7J50_2618 A7J50_2681 A7J50_2681 A7J50_2744 A7J50_2744 A7J50_2941 A7J50_2941 A7J50_2943 A7J50_2943 arnA arnA A7J50_2969 A7J50_2969 A7J50_3112 A7J50_3112 A7J50_3199 A7J50_3199 zwf zwf A7J50_3248 A7J50_3248 A7J50_3335 A7J50_3335 A7J50_3366 A7J50_3366 murB murB A7J50_3413 A7J50_3413 A7J50_3443 A7J50_3443 A7J50_3444 A7J50_3444 A7J50_3529 A7J50_3529 A7J50_3606 A7J50_3606 A7J50_3655 A7J50_3655 A7J50_3705 A7J50_3705 leuB leuB A7J50_3967 A7J50_3967 lldD lldD A7J50_4196 A7J50_4196 A7J50_4228 A7J50_4228 A7J50_4243 A7J50_4243 A7J50_4345 A7J50_4345 A7J50_4424 A7J50_4424 A7J50_4444 A7J50_4444 A7J50_4581 A7J50_4581 zwf-2 zwf-2 A7J50_4697 A7J50_4697 A7J50_4774 A7J50_4774 A7J50_4947 A7J50_4947 ilvC ilvC A7J50_5025 A7J50_5025 aroE-2 aroE-2 A7J50_5197 A7J50_5197 A7J50_5208 A7J50_5208 A7J50_5289 A7J50_5289 pdxA pdxA A7J50_5377 A7J50_5377 lcdH lcdH betA betA A7J50_5520 A7J50_5520 A7J50_5556 A7J50_5556 A7J50_5557 A7J50_5557
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (274 aa)
A7J50_0052Pfam:pfam13618 Gluconate 2-dehydrogenase subunit 3. (250 aa)
A7J50_0053Gluconate 2-dehydrogenase flavoprotein; Pfam:pfam05199 GMC oxidoreductase. (594 aa)
A7J50_0054Alcohol dehydrogenase; Pfam:pfam13442 Cytochrome C oxidase, cbb3-type, subunit III. (432 aa)
A7J50_0394Pfam:pfam03949 Malic enzyme, NAD binding domain. (422 aa)
A7J50_0636Oxidoreductase; Pfam:pfam00106 short chain dehydrogenase. (450 aa)
A7J50_0653Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (228 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (439 aa)
mqoPfam:pfam06039 Malate:quinone oxidoreductase (Mqo). (502 aa)
A7J50_0921Glycerate dehydrogenase; Pfam:pfam02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (321 aa)
A7J50_09672-ketogluconate reductase; Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (324 aa)
A7J50_0992Pfam:pfam03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (488 aa)
A7J50_1088Glucose dehydrogenase; Pfam:pfam13360 PQQ-like domain. (805 aa)
A7J50_1138Glycerol-3-phosphate dehydrogenase; Pfam:pfam01266 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (512 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa)
A7J50_1431Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (370 aa)
A7J50_1542Pfam:pfam00465 Iron-containing alcohol dehydrogenase. (382 aa)
A7J50_1641Pfam:pfam02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (310 aa)
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (380 aa)
fadBFatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
mqo-2Pfam:pfam06039 Malate:quinone oxidoreductase (Mqo). (551 aa)
A7J50_18582-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (321 aa)
A7J50_19302-hydroxy-3-oxopropionate reductase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (296 aa)
gpsAPfam:pfam01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa)
A7J50_2131Pfam:pfam08501 Shikimate dehydrogenase substrate binding domain. (272 aa)
A7J50_2162Choline dehydrogenase; Pfam:pfam05199 GMC oxidoreductase. (548 aa)
A7J50_2233Pfam:pfam00034 Cytochrome c. (448 aa)
A7J50_2276Dihydrofolate reductase; Pfam:pfam02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (315 aa)
A7J50_2345Pfam:pfam01070 FMN-dependent dehydrogenase. (386 aa)
A7J50_2369Iditol 2-dehydrogenase; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (371 aa)
A7J50_2391Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (257 aa)
iolGInositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (336 aa)
A7J50_25793-ketoacyl-ACP reductase; Pfam:pfam00106 short chain dehydrogenase. (447 aa)
A7J50_2583Bifunctional glyoxylate/hydroxypyruvate reductase B; Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (325 aa)
A7J50_2618Pfam:pfam08125 Mannitol dehydrogenase C-terminal domain. (493 aa)
A7J50_2681Pfam:pfam00732 GMC oxidoreductase. (536 aa)
A7J50_2744Aldose sugar dehydrogenase YliI; Pfam:pfam07995 Glucose / Sorbosone dehydrogenase. (385 aa)
A7J50_2941Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (344 aa)
A7J50_2943Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (342 aa)
arnABifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (663 aa)
A7J50_2969Pfam:pfam03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain. (459 aa)
A7J50_3112Pfam:pfam02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (317 aa)
A7J50_3199Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (316 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
A7J50_3248Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (327 aa)
A7J50_3335Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (355 aa)
A7J50_3366Quinate dehydrogenase. (802 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (339 aa)
A7J50_3413Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (329 aa)
A7J50_3443Pfam:pfam00180 Isocitrate/isopropylmalate dehydrogenase. (418 aa)
A7J50_3444Pfam:pfam03971 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (741 aa)
A7J50_3529Deaminase/reductase; Pfam:pfam01872 RibD C-terminal domain. (183 aa)
A7J50_3606Pfam:pfam01370 NAD dependent epimerase/dehydratase family. (274 aa)
A7J50_3655Iditol 2-dehydrogenase; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (359 aa)
A7J50_3705Phosphoesterase; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (350 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa)
A7J50_3967Quinate dehydrogenase; Pfam:pfam13360 PQQ-like domain. (789 aa)
lldDL-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. (380 aa)
A7J50_4196FAD dependent oxidoreductase. (693 aa)
A7J50_4228dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (298 aa)
A7J50_4243dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (298 aa)
A7J50_43453-ketoacyl-ACP reductase; Pfam:pfam00106 short chain dehydrogenase. (248 aa)
A7J50_4424Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
A7J50_4444Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (350 aa)
A7J50_4581Epimerase; Pfam:pfam01370 NAD dependent epimerase/dehydratase family. (245 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (488 aa)
A7J50_46972-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)
A7J50_4774Pfam:pfam00742 Homoserine dehydrogenase. (439 aa)
A7J50_49473-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
A7J50_50254Fe-4S ferredoxin; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. (936 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa)
A7J50_5197Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (378 aa)
A7J50_5208dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (289 aa)
A7J50_5289Pfam:pfam00465 Iron-containing alcohol dehydrogenase. (382 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa)
A7J50_5377Sarcosine oxidase, alpha subunit; Pfam:pfam01571 Aminomethyltransferase folate-binding domain; Belongs to the GcvT family. (1005 aa)
lcdHL-carnitine dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (321 aa)
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (567 aa)
A7J50_5520Pfam:pfam00732 GMC oxidoreductase. (531 aa)
A7J50_5556Pfam:pfam02913 FAD linked oxidases, C-terminal domain. (472 aa)
A7J50_5557Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (409 aa)
Your Current Organism:
Pseudomonas antarctica
NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35
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