STRINGSTRING
A7J50_4697 A7J50_4697 A7J50_2850 A7J50_2850 A7J50_2932 A7J50_2932 tpiA tpiA A7J50_2935 A7J50_2935 A7J50_2975 A7J50_2975 A7J50_2977 A7J50_2977 A7J50_2979 A7J50_2979 A7J50_3018 A7J50_3018 A7J50_3102 A7J50_3102 A7J50_3120 A7J50_3120 A7J50_3192 A7J50_3192 A7J50_3202 A7J50_3202 A7J50_3248 A7J50_3248 A7J50_3272 A7J50_3272 A7J50_3273 A7J50_3273 A7J50_3310 A7J50_3310 aroE aroE A7J50_0031 A7J50_0031 A7J50_0032 A7J50_0032 A7J50_0112 A7J50_0112 A7J50_0117 A7J50_0117 A7J50_0191 A7J50_0191 A7J50_0233 A7J50_0233 A7J50_0264 A7J50_0264 A7J50_0271 A7J50_0271 gpmI gpmI A7J50_0332 A7J50_0332 A7J50_0346 A7J50_0346 hutU hutU A7J50_0353 A7J50_0353 hutH hutH hutI hutI A7J50_0394 A7J50_0394 A7J50_0409 A7J50_0409 A7J50_0412 A7J50_0412 A7J50_0419 A7J50_0419 A7J50_0422 A7J50_0422 A7J50_0424 A7J50_0424 A7J50_0425 A7J50_0425 lcdH lcdH A7J50_5399 A7J50_5399 A7J50_5388 A7J50_5388 glcB glcB bioB bioB bioF bioF A7J50_5345 A7J50_5345 bioC bioC bioD bioD A7J50_5340 A7J50_5340 A7J50_5338 A7J50_5338 A7J50_5287 A7J50_5287 anmK anmK A7J50_5149 A7J50_5149 lipA lipA A7J50_5089 A7J50_5089 A7J50_5082 A7J50_5082 aroE-2 aroE-2 A7J50_5047 A7J50_5047 A7J50_5025 A7J50_5025 tpiA-2 tpiA-2 acsA-2 acsA-2 pgi pgi panC panC panB panB kynB kynB A7J50_4941 A7J50_4941 kynU kynU ispG ispG A7J50_4777 A7J50_4777 A7J50_4734 A7J50_4734 edd edd glk glk A7J50_4719 A7J50_4719 A7J50_4718 A7J50_4718 A7J50_0427 A7J50_0427 A7J50_0448 A7J50_0448 A7J50_0449 A7J50_0449 A7J50_0541 A7J50_0541 A7J50_0599 A7J50_0599 A7J50_0600 A7J50_0600 A7J50_0635 A7J50_0635 A7J50_0636 A7J50_0636 A7J50_0637 A7J50_0637 A7J50_0658 A7J50_0658 ispE ispE ispH ispH A7J50_0914 A7J50_0914 A7J50_1030 A7J50_1030 A7J50_1126 A7J50_1126 A7J50_1290 A7J50_1290 dxr dxr fabZ fabZ accA accA eno eno ispD ispD ispF ispF A7J50_1478 A7J50_1478 A7J50_1505 A7J50_1505 A7J50_1506 A7J50_1506 A7J50_1522 A7J50_1522 A7J50_1570 A7J50_1570 A7J50_1629 A7J50_1629 A7J50_1633 A7J50_1633 A7J50_1666 A7J50_1666 fadB fadB fadA fadA fabV fabV A7J50_1837 A7J50_1837 A7J50_1858 A7J50_1858 A7J50_1875 A7J50_1875 A7J50_1928 A7J50_1928 A7J50_1931 A7J50_1931 A7J50_1932 A7J50_1932 A7J50_1956 A7J50_1956 A7J50_1970 A7J50_1970 fabA fabA A7J50_1978 A7J50_1978 A7J50_2005 A7J50_2005 A7J50_2033 A7J50_2033 A7J50_2131 A7J50_2131 A7J50_2153 A7J50_2153 A7J50_2187 A7J50_2187 A7J50_2197 A7J50_2197 A7J50_2324 A7J50_2324 A7J50_2345 A7J50_2345 A7J50_2390 A7J50_2390 gloB gloB A7J50_2438 A7J50_2438 A7J50_2439 A7J50_2439 A7J50_2491 A7J50_2491 A7J50_2578 A7J50_2578 A7J50_2579 A7J50_2579 A7J50_2580 A7J50_2580 A7J50_2581 A7J50_2581 A7J50_2582 A7J50_2582 A7J50_2602 A7J50_2602 A7J50_2632 A7J50_2632 A7J50_2653 A7J50_2653 A7J50_2657 A7J50_2657 A7J50_2703 A7J50_2703 A7J50_2832 A7J50_2832 A7J50_3326 A7J50_3326 slyX slyX A7J50_4602 A7J50_4602 A7J50_4600 A7J50_4600 A7J50_4599 A7J50_4599 A7J50_4578 A7J50_4578 acsA acsA plsX plsX A7J50_4471 A7J50_4471 A7J50_4470 A7J50_4470 acpP acpP A7J50_4468 A7J50_4468 A7J50_4467 A7J50_4467 A7J50_4454 A7J50_4454 A7J50_4440 A7J50_4440 A7J50_4425 A7J50_4425 A7J50_4424 A7J50_4424 A7J50_4337 A7J50_4337 prpB prpB A7J50_4331 A7J50_4331 A7J50_4330 A7J50_4330 A7J50_4329 A7J50_4329 A7J50_4328 A7J50_4328 A7J50_4316 A7J50_4316 A7J50_4307 A7J50_4307 aceK aceK A7J50_4221 A7J50_4221 A7J50_4163 A7J50_4163 A7J50_4130 A7J50_4130 A7J50_4072 A7J50_4072 A7J50_4009 A7J50_4009 A7J50_3994 A7J50_3994 lldD lldD A7J50_3974 A7J50_3974 A7J50_3935 A7J50_3935 A7J50_3931 A7J50_3931 A7J50_3926 A7J50_3926 accD accD A7J50_3721 A7J50_3721 A7J50_3685 A7J50_3685 A7J50_3679 A7J50_3679 A7J50_3678 A7J50_3678 A7J50_3622 A7J50_3622 A7J50_3576 A7J50_3576 A7J50_3551 A7J50_3551 A7J50_3549 A7J50_3549 A7J50_3544 A7J50_3544 A7J50_3514 A7J50_3514 A7J50_3500 A7J50_3500 A7J50_3452 A7J50_3452 A7J50_3444 A7J50_3444 A7J50_3443 A7J50_3443 A7J50_3340 A7J50_3340 A7J50_3338 A7J50_3338 A7J50_3333 A7J50_3333 A7J50_3331 A7J50_3331 A7J50_3330 A7J50_3330 A7J50_5815 A7J50_5815 A7J50_5806 A7J50_5806 A7J50_5786 A7J50_5786 ubiC ubiC A7J50_5717 A7J50_5717 A7J50_5694 A7J50_5694 A7J50_5580 A7J50_5580 A7J50_5556 A7J50_5556 A7J50_5555 A7J50_5555 A7J50_5515 A7J50_5515 mdcC mdcC A7J50_5470 A7J50_5470 A7J50_5467 A7J50_5467 bioA bioA A7J50_5445 A7J50_5445 pgk pgk A7J50_5428 A7J50_5428
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gene neighborhood
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A7J50_46972-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)
A7J50_2850Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily. (289 aa)
A7J50_2932Pfam:pfam00274 Fructose-bisphosphate aldolase class-I. (347 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
A7J50_2935Oleate hydratase; Pfam:pfam06100 Streptococcal 67 kDa myosin-cross-reactive antigen like family. (539 aa)
A7J50_2975Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
A7J50_2977acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
A7J50_2979Pfam:pfam00501 AMP-binding enzyme. (549 aa)
A7J50_3018Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (173 aa)
A7J50_3102Acyl-CoA dehydrogenase. (353 aa)
A7J50_3120Acetylglucosaminylphosphatidylinositol deacetylase; Pfam:pfam02585 GlcNAc-PI de-N-acetylase. (252 aa)
A7J50_3192Pfam:pfam06434 Aconitate hydratase 2 N-terminus; Belongs to the aconitase/IPM isomerase family. (874 aa)
A7J50_3202Short-chain dehydrogenase; Pfam:pfam13561 Enoyl-(Acyl carrier protein) reductase. (255 aa)
A7J50_3248Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (327 aa)
A7J50_3272Pyoverdine non-ribosomal peptide synthetase; Pfam:pfam00501 AMP-binding enzyme. (3950 aa)
A7J50_3273Pyoverdine synthetase I; Pfam:pfam00501 AMP-binding enzyme. (4684 aa)
A7J50_3310Oxidoreductase; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (319 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (274 aa)
A7J50_00312-dehydro-3-deoxygalactonokinase; Pfam:pfam05035 2-keto-3-deoxy-galactonokinase. (319 aa)
A7J50_0032Pfam:pfam01081 KDPG and KHG aldolase. (206 aa)
A7J50_0112Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. (497 aa)
A7J50_0117Pfam:pfam02771 Acyl-CoA dehydrogenase, N-terminal domain. (393 aa)
A7J50_0191Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
A7J50_0233Monooxygenase; Pfam:pfam08028 Acyl-CoA dehydrogenase, C-terminal domain. (413 aa)
A7J50_0264Putative membrane protein; Pfam:pfam07377 Protein of unknown function (DUF1493). (209 aa)
A7J50_0271Thioesterase; Pfam:pfam13279 Thioesterase-like superfamily. (143 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (508 aa)
A7J50_0332Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (178 aa)
A7J50_0346Histidine utilization repressor; Pfam:pfam07702 UTRA domain. (249 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)
A7J50_0353HutH; Pfam:pfam00221 Aromatic amino acid lyase. (507 aa)
hutHHistidine ammonia-lyase; Pfam:pfam00221 Aromatic amino acid lyase. (510 aa)
hutIImidazolonepropionase; Pfam:pfam13147 Amidohydrolase. (401 aa)
A7J50_0394Pfam:pfam03949 Malic enzyme, NAD binding domain. (422 aa)
A7J50_0409Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa)
A7J50_0412Pfam:pfam02801 Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (388 aa)
A7J50_0419Putative histidine ammonia-lyase; Pfam:pfam00221 Aromatic amino acid lyase. (513 aa)
A7J50_0422Pfam:pfam00501 AMP-binding enzyme. (556 aa)
A7J50_0424Acyl carrier protein; Pfam:pfam00550 Phosphopantetheine attachment site. (84 aa)
A7J50_0425Acyl carrier protein. (89 aa)
lcdHL-carnitine dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (321 aa)
A7J50_5399NADPH dependend quinone reductase; Pfam:pfam05853 Prokaryotic protein of unknown function (DUF849). (295 aa)
A7J50_5388Pfam:pfam00766 Electron transfer flavoprotein FAD-binding domain. (406 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (351 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa)
A7J50_5345Transporter; Pfam:pfam12697 Alpha/beta hydrolase family. (243 aa)
bioCmalonyl-CoA O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (270 aa)
bioDATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa)
A7J50_5340Pfam:pfam12806 Acetyl-CoA dehydrogenase C-terminal like. (601 aa)
A7J50_5338Pfam:pfam12806 Acetyl-CoA dehydrogenase C-terminal like. (590 aa)
A7J50_5287Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (272 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (363 aa)
A7J50_5149Dehydratase; Pfam:pfam01575 MaoC like domain. (151 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (341 aa)
A7J50_5089Pfam:pfam13622 Thioesterase-like superfamily. (289 aa)
A7J50_5082Pfam:pfam14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal. (633 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa)
A7J50_5047Pfam:pfam01817 Chorismate mutase type II. (101 aa)
A7J50_50254Fe-4S ferredoxin; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. (936 aa)
tpiA-2Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
acsA-2acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
pgiPfam:pfam00342 Phosphoglucose isomerase; Belongs to the GPI family. (554 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (266 aa)
kynBKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (216 aa)
A7J50_4941Pfam:pfam00866 Ring hydroxylating beta subunit. (163 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (416 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (369 aa)
A7J50_4777Pfam:pfam03061 Thioesterase superfamily. (137 aa)
A7J50_4734Pfam:pfam00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa)
glkGlucokinase; Pfam:pfam02685 Glucokinase; Belongs to the bacterial glucokinase family. (318 aa)
A7J50_4719Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family. (249 aa)
A7J50_4718Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (483 aa)
A7J50_0427Pfam:pfam13723 Beta-ketoacyl synthase, N-terminal domain. (209 aa)
A7J50_0448Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa)
A7J50_0449Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)
A7J50_0541Putative amino acid oxidase; Pfam:pfam00106 short chain dehydrogenase. (254 aa)
A7J50_0599acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa)
A7J50_0600acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
A7J50_0635Acyl dehydratase; Pfam:pfam01575 MaoC like domain. (282 aa)
A7J50_0636Oxidoreductase; Pfam:pfam00106 short chain dehydrogenase. (450 aa)
A7J50_0637acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
A7J50_0658Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (267 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa)
A7J50_0914Pfam:pfam01553 Acyltransferase. (387 aa)
A7J50_1030Fumarylacetoacetase; Pfam:pfam01557 Fumarylacetoacetate (FAA) hydrolase family. (428 aa)
A7J50_1126Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
A7J50_12902-methylisocitrate lyase; Pfam:pfam13714 Phosphoenolpyruvate phosphomutase. (275 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (235 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa)
A7J50_1478Hypothetical protein; Pfam:pfam05721 Phytanoyl-CoA dioxygenase (PhyH). (325 aa)
A7J50_1505acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
A7J50_1506Protocatechuate 3,4-dioxygenase subunit beta; Pfam:pfam00775 Dioxygenase. (234 aa)
A7J50_1522ACP phosphodiesterase; Pfam:pfam04336 Protein of unknown function, DUF479. (194 aa)
A7J50_1570Urea carboxylase; Pfam:pfam02626 Allophanate hydrolase subunit 2. (1230 aa)
A7J50_1629MBL fold metallo-hydrolase; Pfam:pfam00753 Metallo-beta-lactamase superfamily. (288 aa)
A7J50_1633P-hydroxybenzoate hydroxylase; Pfam:pfam01494 FAD binding domain. (397 aa)
A7J50_1666Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa)
fadBFatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
fadA3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (391 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa)
A7J50_1837Putative acyl-CoA thioesterase II; Pfam:pfam13622 Thioesterase-like superfamily. (265 aa)
A7J50_18582-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (321 aa)
A7J50_1875Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family. (263 aa)
A7J50_1928Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (471 aa)
A7J50_1931Pfam:pfam01261 Xylose isomerase-like TIM barrel; Belongs to the hyi family. (260 aa)
A7J50_1932Glyoxylate carboligase; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Belongs to the TPP enzyme family. (591 aa)
A7J50_1956Dihydrolipoyl dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (478 aa)
A7J50_1970Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa)
fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)
A7J50_1978AMP-binding acetyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (549 aa)
A7J50_2005acyl-CoA dehydrogenase; Pfam:pfam09317 Domain of unknown function (DUF1974). (815 aa)
A7J50_2033NAD(P)H-quinone oxidoreductase; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (320 aa)
A7J50_2131Pfam:pfam08501 Shikimate dehydrogenase substrate binding domain. (272 aa)
A7J50_2153Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
A7J50_2187Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
A7J50_2197Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
A7J50_2324Pfam:pfam03737 Demethylmenaquinone methyltransferase. (217 aa)
A7J50_2345Pfam:pfam01070 FMN-dependent dehydrogenase. (386 aa)
A7J50_2390Putative acetoacetyl-coenzyme A synthetase; Pfam:pfam00501 AMP-binding enzyme. (652 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (255 aa)
A7J50_2438Putative non-ribosomal peptide synthetase; Pfam:pfam00501 AMP-binding enzyme. (4303 aa)
A7J50_2439Putative non-ribosomal peptide synthetase; Pfam:pfam00501 AMP-binding enzyme. (3778 aa)
A7J50_2491Pfam:pfam01557 Fumarylacetoacetate (FAA) hydrolase family. (231 aa)
A7J50_2578Acyl-CoA dehydrogenase; Pfam:pfam09317 Domain of unknown function (DUF1974). (841 aa)
A7J50_25793-ketoacyl-ACP reductase; Pfam:pfam00106 short chain dehydrogenase. (447 aa)
A7J50_2580Acyl dehydratase; Pfam:pfam01575 MaoC like domain. (300 aa)
A7J50_2581acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
A7J50_2582Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (567 aa)
A7J50_2602Pfam:pfam08028 Acyl-CoA dehydrogenase, C-terminal domain. (412 aa)
A7J50_2632Glucose-1-dehydrogenase; Pfam:pfam00106 short chain dehydrogenase. (248 aa)
A7J50_2653PEP phosphonomutase-like enzyme; Pfam:pfam13714 Phosphoenolpyruvate phosphomutase. (266 aa)
A7J50_2657Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
A7J50_2703D-2-hydroxyacid dehydrogenase; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. (473 aa)
A7J50_2832Putative long-chain-fatty-acid-CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (492 aa)
A7J50_3326Phosphoglycerate mutase family protein; Pfam:pfam00300 Histidine phosphatase superfamily (branch 1). (184 aa)
slyXPfam:pfam04102 SlyX; Belongs to the SlyX family. (68 aa)
A7J50_46023-hydroxybutyryl-CoA dehydratase; Pfam:pfam01575 MaoC like domain. (156 aa)
A7J50_4600Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (562 aa)
A7J50_4599Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (563 aa)
A7J50_4578Gluconokinase; Pfam:pfam13671 AAA domain. (177 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (326 aa)
A7J50_4471ACP S-malonyltransferase; Pfam:pfam00698 Acyl transferase domain. (312 aa)
A7J50_44703-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
A7J50_44683-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
A7J50_44674-amino-4-deoxychorismate lyase; Pfam:pfam01063 Aminotransferase class IV. (271 aa)
A7J50_4454Pfam:pfam08241 Methyltransferase domain. (242 aa)
A7J50_4440Electron transfer flavoprotein, alpha subunit; Pfam:pfam00766 Electron transfer flavoprotein FAD-binding domain. (309 aa)
A7J50_4425Acetyl-CoA acetyltransferase; Pfam:pfam02803 Thiolase, C-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
A7J50_4424Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
A7J50_4337Aminodeoxychorismate synthase; Pfam:pfam00425 chorismate binding enzyme. (447 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (297 aa)
A7J50_4331Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family. (375 aa)
A7J50_4330Aconitate hydratase; Pfam:pfam00330 Aconitase family (aconitate hydratase). (864 aa)
A7J50_43293-methylitaconate isomerase; Pfam:pfam04303 PrpF protein. (396 aa)
A7J50_43282-methylcitrate dehydratase; Pfam:pfam03972 MmgE/PrpD family. (494 aa)
A7J50_4316Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
A7J50_4307Nitrate reductase subunit alpha; Pfam:pfam00384 Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (902 aa)
aceKIsocitrate dehydrogenase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (569 aa)
A7J50_42213-oxoacyl-ACP synthase; Pfam:pfam08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal. (373 aa)
A7J50_41637 alpha-ribazole-5'-phosphate phosphatase; Pfam:pfam00300 Histidine phosphatase superfamily (branch 1). (191 aa)
A7J50_4130beta-ketoacyl-ACP synthase; Pfam:pfam08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal. (309 aa)
A7J50_4072methylcrotonoyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. (538 aa)
A7J50_4009Long-chain acyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (608 aa)
A7J50_3994Acetyl-CoA C-acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
lldDL-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. (380 aa)
A7J50_3974Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
A7J50_3935NAD(P)H-quinone oxidoreductase; Pfam:pfam00107 Zinc-binding dehydrogenase. (326 aa)
A7J50_3931Restriction endonuclease subunit S; Pfam:pfam05721 Phytanoyl-CoA dioxygenase (PhyH). (290 aa)
A7J50_3926Pfam:pfam08028 Acyl-CoA dehydrogenase, C-terminal domain. (412 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa)
A7J50_3721GntR family transcriptional regulator; Pfam:pfam04909 Amidohydrolase. (307 aa)
A7J50_3685Pfam:pfam03328 HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family. (266 aa)
A7J50_36792-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Pfam:pfam01557 Fumarylacetoacetate (FAA) hydrolase family. (256 aa)
A7J50_36784-hydroxyphenylacetate isomerase; Pfam:pfam01557 Fumarylacetoacetate (FAA) hydrolase family. (221 aa)
A7J50_3622Dihydrolipoamide dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (459 aa)
A7J50_3576Putative 2,4-dienoyl-CoA reductase; Pfam:pfam00724 NADH:flavin oxidoreductase / NADH oxidase family. (679 aa)
A7J50_3551methylcrotonoyl-CoA carboxylase; Pfam:pfam01039 Carboxyl transferase domain. (535 aa)
A7J50_3549AMP-binding domain protein; Pfam:pfam00501 AMP-binding enzyme. (542 aa)
A7J50_3544Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (409 aa)
A7J50_3514acyl-CoA synthetase. (303 aa)
A7J50_3500Pfam:pfam00171 Aldehyde dehydrogenase family. (538 aa)
A7J50_3452Pfam:pfam00463 Isocitrate lyase family. (441 aa)
A7J50_3444Pfam:pfam03971 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (741 aa)
A7J50_3443Pfam:pfam00180 Isocitrate/isopropylmalate dehydrogenase. (418 aa)
A7J50_3340Dimethylallyltransferase; Pfam:pfam13587 N-terminal domain of DJ-1_PfpI family. (225 aa)
A7J50_3338Pfam:pfam00107 Zinc-binding dehydrogenase. (332 aa)
A7J50_3333methylmalonyl-CoA decarboxylase; Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
A7J50_3331acetyl-CoA acetyltransferase; Pfam:pfam02803 Thiolase, C-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
A7J50_3330AMP-dependent synthetase; Pfam:pfam00501 AMP-binding enzyme. (511 aa)
A7J50_5815Pfam:pfam03061 Thioesterase superfamily. (161 aa)
A7J50_5806Biotin carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (471 aa)
A7J50_5786Long-chain acyl-CoA thioester hydrolase; Pfam:pfam03061 Thioesterase superfamily. (134 aa)
ubiCChorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (187 aa)
A7J50_5717Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
A7J50_5694Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. (640 aa)
A7J50_5580Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
A7J50_5556Pfam:pfam02913 FAD linked oxidases, C-terminal domain. (472 aa)
A7J50_5555FAH family protein; Pfam:pfam01557 Fumarylacetoacetate (FAA) hydrolase family. (221 aa)
A7J50_5515Pfam:pfam12697 Alpha/beta hydrolase family. (332 aa)
mdcCMalonate decarboxylase acyl carrier protein; Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism. (99 aa)
A7J50_5470Malonate decarboxylase subunit beta; Pfam:pfam01039 Carboxyl transferase domain. (280 aa)
A7J50_5467Malonate decarboxylase subunit epsilon; Pfam:pfam00698 Acyl transferase domain. (299 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (468 aa)
A7J50_5445Thioesterase; Pfam:pfam03061 Thioesterase superfamily. (134 aa)
pgkPfam:pfam00162 Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa)
A7J50_5428Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
Your Current Organism:
Pseudomonas antarctica
NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35
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