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A7J50_0054 A7J50_0054 pckA pckA gpmI gpmI fbp fbp A7J50_0448 A7J50_0448 A7J50_0449 A7J50_0449 A7J50_0534 A7J50_0534 eno eno A7J50_1431 A7J50_1431 A7J50_1542 A7J50_1542 A7J50_1691 A7J50_1691 A7J50_1928 A7J50_1928 A7J50_1956 A7J50_1956 A7J50_2074 A7J50_2074 A7J50_2199 A7J50_2199 A7J50_2233 A7J50_2233 A7J50_2774 A7J50_2774 A7J50_2932 A7J50_2932 tpiA tpiA A7J50_2941 A7J50_2941 A7J50_2943 A7J50_2943 A7J50_2979 A7J50_2979 A7J50_3335 A7J50_3335 A7J50_3349 A7J50_3349 A7J50_3500 A7J50_3500 A7J50_3608 A7J50_3608 A7J50_3622 A7J50_3622 A7J50_4316 A7J50_4316 A7J50_4444 A7J50_4444 acsA acsA A7J50_4718 A7J50_4718 glk glk A7J50_4734 A7J50_4734 pgi pgi acsA-2 acsA-2 tpiA-2 tpiA-2 A7J50_5161 A7J50_5161 A7J50_5428 A7J50_5428 pgk pgk A7J50_5720 A7J50_5720 A7J50_5787 A7J50_5787
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A7J50_0054Alcohol dehydrogenase; Pfam:pfam13442 Cytochrome C oxidase, cbb3-type, subunit III. (432 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (508 aa)
fbpFructose-1,6-bisphosphatase class 1; Pfam:pfam00316 Fructose-1-6-bisphosphatase; Belongs to the FBPase class 1 family. (336 aa)
A7J50_0448Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa)
A7J50_0449Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)
A7J50_0534Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (496 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
A7J50_1431Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (370 aa)
A7J50_1542Pfam:pfam00465 Iron-containing alcohol dehydrogenase. (382 aa)
A7J50_1691Pfam:pfam02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (487 aa)
A7J50_1928Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (471 aa)
A7J50_1956Dihydrolipoyl dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (478 aa)
A7J50_2074Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (471 aa)
A7J50_2199acyl-CoA synthetase; Pfam:pfam13549 ATP-grasp domain. (702 aa)
A7J50_2233Pfam:pfam00034 Cytochrome c. (448 aa)
A7J50_2774Pfam:pfam02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (547 aa)
A7J50_2932Pfam:pfam00274 Fructose-bisphosphate aldolase class-I. (347 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
A7J50_2941Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (344 aa)
A7J50_2943Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (342 aa)
A7J50_2979Pfam:pfam00501 AMP-binding enzyme. (549 aa)
A7J50_3335Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (355 aa)
A7J50_3349Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (382 aa)
A7J50_3500Pfam:pfam00171 Aldehyde dehydrogenase family. (538 aa)
A7J50_3608Pfam:pfam01263 Aldose 1-epimerase. (296 aa)
A7J50_3622Dihydrolipoamide dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (459 aa)
A7J50_4316Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
A7J50_4444Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (350 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
A7J50_4718Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (483 aa)
glkGlucokinase; Pfam:pfam02685 Glucokinase; Belongs to the bacterial glucokinase family. (318 aa)
A7J50_4734Pfam:pfam00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
pgiPfam:pfam00342 Phosphoglucose isomerase; Belongs to the GPI family. (554 aa)
acsA-2acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
tpiA-2Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
A7J50_5161Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (506 aa)
A7J50_5428Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pgkPfam:pfam00162 Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa)
A7J50_5720Pfam:pfam02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (465 aa)
A7J50_5787Pfam:pfam01263 Aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (299 aa)
Your Current Organism:
Pseudomonas antarctica
NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35
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