STRINGSTRING
A7J50_0409 A7J50_0409 A7J50_0410 A7J50_0410 A7J50_0412 A7J50_0412 A7J50_0599 A7J50_0599 A7J50_0600 A7J50_0600 A7J50_0636 A7J50_0636 A7J50_1082 A7J50_1082 A7J50_1083 A7J50_1083 fabZ fabZ accA accA fabV fabV A7J50_1970 A7J50_1970 fabA fabA A7J50_1978 A7J50_1978 A7J50_2579 A7J50_2579 A7J50_2582 A7J50_2582 A7J50_3691 A7J50_3691 accD accD A7J50_4130 A7J50_4130 A7J50_4345 A7J50_4345 A7J50_4468 A7J50_4468 A7J50_4470 A7J50_4470 A7J50_4471 A7J50_4471 A7J50_4599 A7J50_4599 A7J50_4600 A7J50_4600
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A7J50_0409Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa)
A7J50_04103-ketoacyl-ACP reductase; Pfam:pfam00106 short chain dehydrogenase. (242 aa)
A7J50_0412Pfam:pfam02801 Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (388 aa)
A7J50_0599acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa)
A7J50_0600acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
A7J50_0636Oxidoreductase; Pfam:pfam00106 short chain dehydrogenase. (450 aa)
A7J50_1082Pfam:pfam00106 short chain dehydrogenase. (253 aa)
A7J50_10833-oxoacyl-ACP reductase; Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa)
A7J50_1970Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa)
fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)
A7J50_1978AMP-binding acetyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (549 aa)
A7J50_25793-ketoacyl-ACP reductase; Pfam:pfam00106 short chain dehydrogenase. (447 aa)
A7J50_2582Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (567 aa)
A7J50_3691Oxidoreductase; Pfam:pfam00106 short chain dehydrogenase. (251 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa)
A7J50_4130beta-ketoacyl-ACP synthase; Pfam:pfam08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal. (309 aa)
A7J50_43453-ketoacyl-ACP reductase; Pfam:pfam00106 short chain dehydrogenase. (248 aa)
A7J50_44683-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
A7J50_44703-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
A7J50_4471ACP S-malonyltransferase; Pfam:pfam00698 Acyl transferase domain. (312 aa)
A7J50_4599Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (563 aa)
A7J50_4600Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (562 aa)
Your Current Organism:
Pseudomonas antarctica
NCBI taxonomy Id: 219572
Other names: CCUG 49625, DSM 15318, LMG 22709, LMG:22709, MTCC 4992, Pseudomonas antarctica Reddy et al. 2004, strain CMS 35
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