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| | A7J50_0073 | Hydroperoxidase; Serves to protect cells from the toxic effects of hydrogen peroxide. (713 aa) |
| | A7J50_0112 | Pfam:pfam13336 Acetyl-CoA hydrolase/transferase C-terminal domain. (497 aa) |
| | A7J50_0239 | Serine O-acetyltransferase. (308 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa) |
| | gpmI | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (508 aa) |
| | fbp | Fructose-1,6-bisphosphatase class 1; Pfam:pfam00316 Fructose-1-6-bisphosphatase; Belongs to the FBPase class 1 family. (336 aa) |
| | A7J50_0394 | Pfam:pfam03949 Malic enzyme, NAD binding domain. (422 aa) |
| | A7J50_0448 | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (548 aa) |
| | A7J50_0449 | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa) |
| | A7J50_0492 | Phosphoserine phosphatase; Pfam:pfam13740 ACT domain. (404 aa) |
| | A7J50_0599 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa) |
| | A7J50_0600 | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa) |
| | A7J50_0637 | acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa) |
| | A7J50_0659 | Pfam:pfam00171 Aldehyde dehydrogenase family. (497 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | A7J50_0768 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (699 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa) |
| | mqo | Pfam:pfam06039 Malate:quinone oxidoreductase (Mqo). (502 aa) |
| | A7J50_0921 | Glycerate dehydrogenase; Pfam:pfam02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (321 aa) |
| | A7J50_1041 | Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (881 aa) |
| | accA | acetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa) |
| | A7J50_1431 | Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (370 aa) |
| | A7J50_1432 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (281 aa) |
| | A7J50_1469 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (364 aa) |
| | A7J50_1664 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa) |
| | A7J50_1666 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa) |
| | fadB | Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa) |
| | A7J50_1691 | Pfam:pfam02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (487 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (308 aa) |
| | mqo-2 | Pfam:pfam06039 Malate:quinone oxidoreductase (Mqo). (551 aa) |
| | fabV | trans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa) |
| | serC | MFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (324 aa) |
| | A7J50_1928 | Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (471 aa) |
| | A7J50_1929 | Hydroxypyruvate reductase; Pfam:pfam13660 Domain of unknown function (DUF4147). (426 aa) |
| | A7J50_1949 | Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family. (429 aa) |
| | A7J50_1950 | Pfam:pfam01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit. (124 aa) |
| | A7J50_1951 | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa) |
| | A7J50_1952 | Succinate dehydrogenase; Pfam:pfam00890 FAD binding domain; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa) |
| | A7J50_1953 | Succinate dehydrogenase, iron-sulfur protein; Pfam:pfam13085 2Fe-2S iron-sulfur cluster binding domain. (234 aa) |
| | A7J50_1954 | 2-oxoglutarate dehydrogenase E1; Pfam:pfam02779 Transketolase, pyrimidine binding domain. (943 aa) |
| | A7J50_1955 | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (408 aa) |
| | A7J50_1956 | Dihydrolipoyl dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (478 aa) |
| | sucC | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (404 aa) |
| | sucD | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa) |
| | A7J50_2099 | Glucose-1-dehydrogenase; Pfam:pfam13561 Enoyl-(Acyl carrier protein) reductase. (266 aa) |
| | A7J50_2153 | Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (307 aa) |
| | A7J50_2326 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (895 aa) |
| | A7J50_2356 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (686 aa) |
| | A7J50_2374 | Pfam:pfam02502 Ribose/Galactose Isomerase. (153 aa) |
| | A7J50_2387 | Ketodeoxygluconokinase; Pfam:pfam00294 pfkB family carbohydrate kinase. (301 aa) |
| | A7J50_2581 | acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa) |
| | A7J50_2664 | Pfam:pfam08714 Formaldehyde-activating enzyme (Fae). (170 aa) |
| | A7J50_2932 | Pfam:pfam00274 Fructose-bisphosphate aldolase class-I. (347 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa) |
| | ackA | Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa) |
| | A7J50_2976 | Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (375 aa) |
| | A7J50_2977 | acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | A7J50_2979 | Pfam:pfam00501 AMP-binding enzyme. (549 aa) |
| | A7J50_3192 | Pfam:pfam06434 Aconitate hydratase 2 N-terminus; Belongs to the aconitase/IPM isomerase family. (874 aa) |
| | A7J50_3221 | 3-carboxymuconate cyclase; Pfam:pfam10282 Lactonase, 7-bladed beta-propeller. (391 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa) |
| | A7J50_3248 | Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (327 aa) |
| | A7J50_3283 | Formamidase; Pfam:pfam03069 Acetamidase/Formamidase family. (409 aa) |
| | A7J50_3331 | acetyl-CoA acetyltransferase; Pfam:pfam02803 Thiolase, C-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | A7J50_3369 | Pfam:pfam00171 Aldehyde dehydrogenase family. (499 aa) |
| | A7J50_3443 | Pfam:pfam00180 Isocitrate/isopropylmalate dehydrogenase. (418 aa) |
| | A7J50_3444 | Pfam:pfam03971 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (741 aa) |
| | A7J50_3452 | Pfam:pfam00463 Isocitrate lyase family. (441 aa) |
| | A7J50_3500 | Pfam:pfam00171 Aldehyde dehydrogenase family. (538 aa) |
| | A7J50_3558 | Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (360 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | A7J50_3622 | Dihydrolipoamide dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (459 aa) |
| | accD | acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa) |
| | A7J50_3910 | methylmalonyl-CoA epimerase; Pfam:pfam13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (151 aa) |
| | fumC-2 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa) |
| | A7J50_4316 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) |
| | A7J50_4321 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (304 aa) |
| | A7J50_4322 | Serine O-acetyltransferase. (330 aa) |
| | A7J50_4424 | Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Belongs to the enoyl-CoA hydratase/isomerase family. (715 aa) |
| | A7J50_4425 | Acetyl-CoA acetyltransferase; Pfam:pfam02803 Thiolase, C-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | acsA | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa) |
| | A7J50_4578 | Gluconokinase; Pfam:pfam13671 AAA domain. (177 aa) |
| | A7J50_4602 | 3-hydroxybutyryl-CoA dehydratase; Pfam:pfam01575 MaoC like domain. (156 aa) |
| | A7J50_4606 | Pfam:pfam01081 KDPG and KHG aldolase. (221 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (237 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (488 aa) |
| | A7J50_4655 | Pfam:pfam00696 Amino acid kinase family; Belongs to the carbamate kinase family. (309 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (946 aa) |
| | A7J50_4660 | Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | A7J50_4661 | Pfam:pfam01571 Aminomethyltransferase folate-binding domain. (374 aa) |
| | A7J50_4718 | Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (483 aa) |
| | A7J50_4721 | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | glk | Glucokinase; Pfam:pfam02685 Glucokinase; Belongs to the bacterial glucokinase family. (318 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | A7J50_4734 | Pfam:pfam00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | A7J50_4838 | Serine acetyltransferase. (261 aa) |
| | A7J50_4948 | Pfam:pfam00171 Aldehyde dehydrogenase family. (505 aa) |
| | pgi | Pfam:pfam00342 Phosphoglucose isomerase; Belongs to the GPI family. (554 aa) |
| | acsA-2 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa) |
| | tpiA-2 | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | A7J50_5062 | Catalase; Pfam:pfam00199 Catalase; Belongs to the catalase family. (513 aa) |
| | A7J50_5224 | Catalase; Pfam:pfam00199 Catalase; Belongs to the catalase family. (482 aa) |
| | A7J50_5288 | Pfam:pfam00834 Ribulose-phosphate 3 epimerase family; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa) |
| | glcB | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa) |
| | A7J50_5374 | Aldehyde dismutase; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (399 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | A7J50_5405 | Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | A7J50_5428 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | pgk | Pfam:pfam00162 Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | A7J50_5433 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa) |
| | A7J50_5447 | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (281 aa) |
| | ilvA | L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (223 aa) |
| | A7J50_5557 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (409 aa) |
| | gcvH-2 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvT | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (360 aa) |
| | A7J50_5805 | Pfam:pfam02436 Conserved carboxylase domain. (602 aa) |
| | A7J50_5806 | Biotin carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (471 aa) |
