| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STY0226 | STY2786 | gene:17584260 | gene:17586677 | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.555 |
| STY0226 | STY2789 | gene:17584260 | gene:17586680 | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | Putative L-cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate; Belongs to the class-V pyridoxal-phosphate-dependent am [...] | 0.653 |
| STY0226 | STY2790 | gene:17584260 | gene:17586681 | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | Conserved hypothetical protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.508 |
| STY0226 | STY3616 | gene:17584260 | gene:17587468 | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.428 |
| STY0226 | STY4285 | gene:17584260 | gene:17588116 | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.919 |
| STY0226 | nifU | gene:17584260 | gene:17586679 | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.688 |
| STY2783 | STY2784 | gene:17586674 | gene:17586675 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | Ferredoxin; Orthologue of E. coli fdx (FER_ECOLI); Fasta hit to FER_ECOLI (110 aa), 95% identity in 110 aa overlap. | 0.992 |
| STY2783 | STY2785 | gene:17586674 | gene:17586676 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.960 |
| STY2783 | STY2786 | gene:17586674 | gene:17586677 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.978 |
| STY2783 | STY2787 | gene:17586674 | gene:17586678 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | Conserved hypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. | 0.831 |
| STY2783 | STY2789 | gene:17586674 | gene:17586680 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | Putative L-cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate; Belongs to the class-V pyridoxal-phosphate-dependent am [...] | 0.846 |
| STY2783 | STY2790 | gene:17586674 | gene:17586681 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | Conserved hypothetical protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.558 |
| STY2783 | STY3616 | gene:17586674 | gene:17587468 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.658 |
| STY2783 | STY4285 | gene:17586674 | gene:17588116 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.606 |
| STY2783 | nifU | gene:17586674 | gene:17586679 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.880 |
| STY2784 | STY2783 | gene:17586675 | gene:17586674 | Ferredoxin; Orthologue of E. coli fdx (FER_ECOLI); Fasta hit to FER_ECOLI (110 aa), 95% identity in 110 aa overlap. | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. | 0.992 |
| STY2784 | STY2785 | gene:17586675 | gene:17586676 | Ferredoxin; Orthologue of E. coli fdx (FER_ECOLI); Fasta hit to FER_ECOLI (110 aa), 95% identity in 110 aa overlap. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.990 |
| STY2784 | STY2786 | gene:17586675 | gene:17586677 | Ferredoxin; Orthologue of E. coli fdx (FER_ECOLI); Fasta hit to FER_ECOLI (110 aa), 95% identity in 110 aa overlap. | Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.995 |
| STY2784 | STY2787 | gene:17586675 | gene:17586678 | Ferredoxin; Orthologue of E. coli fdx (FER_ECOLI); Fasta hit to FER_ECOLI (110 aa), 95% identity in 110 aa overlap. | Conserved hypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. | 0.920 |
| STY2784 | STY2789 | gene:17586675 | gene:17586680 | Ferredoxin; Orthologue of E. coli fdx (FER_ECOLI); Fasta hit to FER_ECOLI (110 aa), 95% identity in 110 aa overlap. | Putative L-cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate; Belongs to the class-V pyridoxal-phosphate-dependent am [...] | 0.964 |