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STY0002 STY0002 STY0003 STY0003 STY0004 STY0004 STY0073 STY0073 STY0236 STY0236 STY0361 STY0361 STY0366 STY0366 STY0367 STY0367 STY0419 STY0419 STY0421 STY0421 STY0626 STY0626 STY0646 STY0646 STY0647 STY0647 STY0752 STY0752 STY0753 STY0753 STY0754 STY0754 STY0801 STY0801 STY0977 STY0977 STY0978 STY0978 STY1078 STY1078 STY1159 STY1159 STY1160 STY1160 STY1324 STY1324 STY1325 STY1325 STY1326 STY1326 STY1327 STY1327 STY1328 STY1328 aroD aroD STY1763 STY1763 STY1815 STY1815 aroQ aroQ gdhA gdhA STY1954 STY1954 STY1978 STY1978 STY2280 STY2280 STY2281 STY2281 STY2282 STY2282 STY2283 STY2283 STY2284 STY2284 STY2285 STY2285 STY2286 STY2286 STY2287 STY2287 STY2416 STY2416 STY2431 STY2431 STY2595 STY2595 STY2596 STY2596 STY2598 STY2598 STY2599 STY2599 STY2600 STY2600 STY2601 STY2601 STY2602 STY2602 STY2616 STY2616 STY2721 STY2721 STY2727 STY2727 STY2782 STY2782 STY2854 STY2854 STY2856 STY2856 STY2857 STY2857 STY2944 STY2944 STY3130 STY3130 STY3157 STY3157 STY3218 STY3218 STY3228 STY3228 STY3243 STY3243 STY3248 STY3248 STY3333 STY3333 STY3470 STY3470 STY3510 STY3510 STY3511 STY3511 STY3594 STY3594 STY3595 STY3595 STY3612 STY3612 STY3750 STY3750 STY3751 STY3751 STY3752 STY3752 STY3753 STY3753 STY3761 STY3761 STY3768 STY3768 STY3769 STY3769 STY3770 STY3770 STY3874 STY3874 STY3924 STY3924 ggt ggt STY4271 STY4271 aroK aroK aroB aroB pabA pabA argD argD aroE aroE metA metA STY4405 STY4405 STY4416 STY4416 STY4444 STY4444 STY4816 STY4816
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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STY0002Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa)
STY0003Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)
STY0004Threonine synthase; Orthologue of E. coli thrC (THRC_ECOLI); Fasta hit to THRC_ECOLI (428 aa), 93% identity in 428 aa overlap. (428 aa)
STY0073Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)
STY02362,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Orthologue of E. coli dapD (DAPD_ECOLI); Fasta hit to DAPD_ECOLI (274 aa), 96% identity in 274 aa overlap; Belongs to the transferase hexapeptide repeat family. (274 aa)
STY0361Aminoacyl-histidine dipeptidase precursor; Orthologue of E. coli pepD (PEPD_ECOLI); Fasta hit to PEPD_ECOLI (484 aa), 92% identity in 484 aa overlap. (485 aa)
STY0366Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)
STY0367Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa)
STY0419Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa)
STY0421Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (181 aa)
STY0626Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. (372 aa)
STY0646Putative oxidoreductase; Fasta hit to GLDA_ECOLI (367 aa), 32% identity in 360 aa overlap; Orthologue of E. coli ybdH (YBDH_ECOLI); Fasta hit to YBDH_ECOLI (362 aa), 82% identity in 361 aa overlap. (362 aa)
STY0647Putative aminotransferase; Similar to Escherichia coli hypothetical aminotransferase YbdL ybdL SW:YBDL_ECOLI (P77806) (386 aa) fasta scores: E(): 0, 85.2% id in 386 aa, and to Thermus aquaticus aspartate aminotransferase aspC SW:AAT_THETH (Q56232) (385 aa) fasta scores: E(): 3e-31, 32.2% id in 379 aa; Orthologue of E. coli YBDL_ECOLI; Fasta hit to YBDL_ECOLI (386 aa), 85% identity in 386 aa overlap. (386 aa)
STY0752Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap. (218 aa)
STY0753Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap. (310 aa)
STY0754Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (244 aa)
STY0801Phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthetase) phenylalanine repressible; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (350 aa)
STY0977Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa)
STY09783-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa)
STY1078Orthologue of E. coli pepN (AMPN_ECOLI); Fasta hit to AMPN_ECOLI (869 aa), 94% identity in 869 aa overlap. (870 aa)
STY1159Proline dehydrogenase (proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1320 aa)
STY1160Sodium/proline symporter (proline permease); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (502 aa)
STY1324Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa)
STY1325Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
STY1326Indole-3-glycerol phosphate synthase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity). (452 aa)
STY1327Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (531 aa)
STY1328Anthranilate synthase component I; Orthologue of E. coli trpE (TRPE_ECOLI); Fasta hit to TRPE_ECOLI (520 aa), 90% identity in 520 aa overlap. (520 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of Lys-170 at the active site; Belongs to the type-I 3-dehydroquinase family. (252 aa)
STY17633-deoxy-D-arabinoheptulosonate 7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (348 aa)
STY1815NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. (447 aa)
aroQPutative chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (181 aa)
gdhASimilar to Thermotoga maritima glutamate dehydrogenase gdha or gdh or tm1015 SW:DHE3_THEMA (P96110) (415 aa) fasta scores: E(): 0, 55.9% id in 388 aa, and to Clostridium difficile NAD-specific glutamate dehydrogenase gluD SW:DHE2_CLODI (P27346) (421 aa) fasta scores: E(): 0, 47.8% id in 391 aa; Paralogue of E. coli gdhA (DHE4_ECOLI); Fasta hit to DHE4_ECOLI (447 aa), 34% identity in 363 aa overlap; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (389 aa)
STY1954Para-aminobenzoate synthase component I; Orthologue of E. coli pabB (PABB_ECOLI); Fasta hit to PABB_ECOLI (453 aa), 76% identity in 452 aa overlap. (454 aa)
STY1978Similar to Escherichia coli hypothetical 20.3 kDa protein in prc-pphA intergenic region SW:YEBR_ECOLI (P76270) (183 aa) fasta scores: E(): 0, 83.8% id in 173 aa, and to Zymomonas mobilis hypothetical 17.7 kDa protein in lpd 3'region SW:YLP6_ZYMMO (O66116) (161 aa) fasta scores: E(): 2e-22, 41.5% id in 147 aa. (194 aa)
STY2280ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (299 aa)
STY2281Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa)
STY2282Similar to Salmonella typhimurium histidinol-phosphate aminotransferase hisC SW:HIS8_SALTY (P10369) (359 aa) fasta scores: E(): 0, 98.6% id in 359 aa; Orthologue of E. coli hisC (HIS8_ECOLI); Fasta hit to HIS8_ECOLI (356 aa), 89% identity in 355 aa overlap; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa)
STY2283Imidazoleglycerol-phosphate dehydratase; Similar to Salmonella typhimurium histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase hisB SW:HIS7_SALTY (P10368) (354 aa) fasta scores: E(): 0, 97.5% id in 355 aa; Orthologue of E. coli hisB (HIS7_ECOLI); Fasta hit to HIS7_ECOLI (355 aa), 96% identity in 355 aa overlap; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (355 aa)
STY2284Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity). (196 aa)
STY2285Similar to Salmonella typhimurium phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA SW:HIS4_SALTY (P10372) (246 aa) fasta scores: E(): 0, 96.3% id in 246 aa; Orthologue of E. coli hisA (HIS4_ECOLI); Fasta hit to HIS4_ECOLI (245 aa), 94% identity in 244 aa overlap. (245 aa)
STY2286Cyclase HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). (258 aa)
STY2287phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; Similar to Salmonella typhimurium histidine biosynthesis bifunctional protein HisI [includes: phosphoribosyl-AMP cyclohydrolase hisI SW:HIS2_SALTY (P10367) (203 aa) fasta scores: E(): 0, 97.5% id in 203 aa; Orthologue of E. coli hisI (HIS2_ECOLI); Fasta hit to HIS2_ECOLI (203 aa), 91% identity in 203 aa overlap; In the C-terminal section; belongs to the PRA-PH family. (203 aa)
STY2416Putative oxidoreductase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). (413 aa)
STY2431Putative hydrolase; Similar, except at N-terminus, to phosphoserine phosphatases e.g. Escherichia coli phosphoserine phosphatase serB SW:SERB_ECOLI (P06862) (322 aa) fasta scores: E(): 4.2e-22, 41.0% id in 188 aa. (295 aa)
STY2595DedD protein; Non-essential cell division protein that could be required for efficient cell constriction. (224 aa)
STY2596Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. (422 aa)
STY2598DedA protein (dsg-1 protein); Fasta hit to YQJA_ECOLI (220 aa), 32% identity in 195 aa overlap; Orthologue of E. coli dedA (DEDA_ECOLI); Fasta hit to DEDA_ECOLI (219 aa), 97% identity in 219 aa overlap. (219 aa)
STY2599tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (270 aa)
STY2600Putative semialdehyde dehydrogenase; Orthologue of E. coli usg (USG_ECOLI); Fasta hit to USG_ECOLI (337 aa), 89% identity in 337 aa overlap; Belongs to the aspartate-semialdehyde dehydrogenase family. (337 aa)
STY2601Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (378 aa)
STY2602Div protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system. (333 aa)
STY2616Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa)
STY2721Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa)
STY2727Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
STY2782Peptidase B (leucyl aminopeptidase); Probably plays an important role in intracellular peptide degradation. (427 aa)
STY2854Chorismate mutase-P/prephenate dehydratase; Orthologue of E. coli pheA (PHEA_ECOLI); Fasta hit to PHEA_ECOLI (386 aa), 91% identity in 385 aa overlap. (386 aa)
STY2856Chorismate mutase/prephenate dehydrogenase; Orthologue of E. coli tyrA (TYRA_ECOLI); Fasta hit to TYRA_ECOLI (373 aa), 95% identity in 372 aa overlap. (373 aa)
STY2857Phospho-2-dehydro-3-deoxyheptonate aldolase, tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP); Belongs to the class-I DAHP synthase family. (356 aa)
STY2944Gamma-glutamylcysteine synthetase; Similar to Salmonella typhimurium LT2 glutamate--cysteine ligase SW:GSH1_SALTY (O68838) (518 aa) fasta scores: E(): 0, 98.6% id in 518 aa; Orthologue of E. coli gshA (GSH1_ECOLI); Fasta hit to GSH1_ECOLI (518 aa), 93% identity in 518 aa overlap; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (518 aa)
STY3130N-acetylglutamate synthase; Orthologue of E. coli argA (ARGA_ECOLI); Fasta hit to ARGA_ECOLI (443 aa), 94% identity in 443 aa overlap; Belongs to the acetyltransferase family. ArgA subfamily. (443 aa)
STY3157Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa)
STY3218D-3-phosphoglycerate dehydrogenase; Orthologue of E. coli serA (SERA_ECOLI); Fasta hit to SERA_ECOLI (409 aa), 96% identity in 409 aa overlap; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa)
STY3228D-erythrose 4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (348 aa)
STY3243S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (384 aa)
STY3248Glutathione synthetase; Orthologue of E. coli gshB (GSHB_ECOLI); Fasta hit to GSHB_ECOLI (316 aa), 90% identity in 315 aa overlap. (315 aa)
STY3333Beta-cystathionase; Fasta hit to METB_ECOLI (386 aa), 32% identity in 398 aa overlap; Orthologue of E. coli metC (METC_ECOLI); Fasta hit to METC_ECOLI (395 aa), 87% identity in 395 aa overlap. (395 aa)
STY3470Argininosuccinate synthetase; Orthologue of E. coli argG (ASSY_ECOLI); Fasta hit to ASSY_ECOLI (446 aa), 96% identity in 446 aa overlap; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (469 aa)
STY3510Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 95.4% id in 1486 aa and to Pseudomonas aeruginosa glutamate synthase large subunit GltB TR:P95456 (EMBL:U81261) (1482 aa) fasta scores: E(): 0, 60.9% id in 1476 aa. (1486 aa)
STY3511Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap. (472 aa)
STY35945-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (754 aa)
STY3595Trans-activator of metE and metH; Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. It is also a negative regulator of its own expression (By similarity). Belongs to the LysR transcriptional regulatory family. (317 aa)
STY3612Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa)
STY3750Argininosuccinate lyase; Orthologue of E. coli argH (ARLY_ECOLI); Fasta hit to ARLY_ECOLI (457 aa), 95% identity in 456 aa overlap. (458 aa)
STY3751Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa)
STY3752N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa)
STY3753Acetylornithine deacetylase; Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde. (383 aa)
STY37615,10 methylenetetrahydrofolate reductase; Orthologue of E. coli metF (METF_ECOLI); Fasta hit to METF_ECOLI (296 aa), 96% identity in 296 aa overlap; Belongs to the methylenetetrahydrofolate reductase family. (296 aa)
STY3768Bifunctional aspartokinase II/homoserine dehydrogenase IIcan I write; Fasta hit to AK1H_ECOLI (820 aa), 30% identity in 823 aa overlap; Orthologue of E. coli metL (AK2H_ECOLI); Fasta hit to AK2H_ECOLI (809 aa), 94% identity in 809 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa)
STY3769Cystathionine gamma-synthase; Fasta hit to METC_ECOLI (395 aa), 31% identity in 394 aa overlap; Orthologue of E. coli metB (METB_ECOLI); Fasta hit to METB_ECOLI (386 aa), 96% identity in 386 aa overlap. (386 aa)
STY3770Repressor of the methionine regulon; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. It is also autoregulated (By similarity); Belongs to the MetJ family. (105 aa)
STY3874Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (469 aa)
STY3924Putative shikimate 5-dehydrogenase; Similar to Haemophilus influenzae hypothetical protein SW:YDIB_HAEIN () (271 aa) fasta scores: E(): 4.9e-27, 51.7% id in 267 aa, and in parts to several others including: Nicotiana tabacum dehydroquinate dehydratase/shikimate dehydrogenase precursor TR:Q42947 (EMBL:L32794) (579 aa) fasta scores: E(): 6.8e-07, 26.0% id in 289 aa. (256 aa)
ggtSimilar to Escherichia coli gamma-glutamyltranspeptidase precursor ggt SW:GGT_ECOLI (P18956) (580 aa) fasta scores: E(): 0, 91.4% id in 580 aa, and to Helicobacter pylori J99 gamma-glutamyltranspeptidase ggt TR:Q9ZK95 (EMBL:AE001532) (567 aa) fasta scores: E(): 0, 52.7% id in 537 aa. Contains N-terminal signal sequence, probable secreted protein. (580 aa)
STY4271Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (362 aa)
pabASimilar to Salmonella typhimurium para-aminobenzoate synthase glutamine amidotransferase component ii pabA SW:PABA_SALTY (P06193) (187 aa) fasta scores: E(): 0, 99.5% id in 187 aa, and to Escherichia coli para-aminobenzoate synthase glutamine amidotransferase component ii pabA SW:PABA_ECOLI (P00903) (187 aa) fasta scores: E(): 0, 85.0% id in 187 aa. (187 aa)
argDAcetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways. (405 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa)
metAHomoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (309 aa)
STY4405B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa)
STY4416Similar to Escherichia coli lysine-sensitive aspartokinase III LysC SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 93.3% id in 449 aa; Belongs to the aspartokinase family. (449 aa)
STY4444Similar to Salmonella typhimurium aromatic-amino-acid aminotransferase SW:TYRB_SALTY (P74861) (397 aa) fasta scores: E(): 0, 98.0% id in 397 aa, and to Escherichia coli aromatic-amino-acid aminotransferase tyrB SW:TYRB_ECOLI (P04693) (397 aa) fasta scores: E(): 0, 88.9% id in 397 aa. (397 aa)
STY4816Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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