(6 nodes) Mixed, incl. Cyclophilin-like domain superfamily, and Glutamate dehydrogenase network (Salmonella enterica Typhi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STY0752	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap. (218 aa)
	STY0753	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap. (310 aa)
	STY0754	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (244 aa)
	STY1815	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. (447 aa)
	STY3511	Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap. (472 aa)
	STY3874	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (469 aa)

Your Current Organism:

Salmonella enterica Typhi

NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
STY0752	STY0753	gene:17584761	gene:17584762	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	0.999
STY0752	STY0754	gene:17584761	gene:17584763	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	0.999
STY0752	STY1815	gene:17584761	gene:17585747	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	0.800
STY0752	STY3511	gene:17584761	gene:17587361	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap.	0.800
STY0752	STY3874	gene:17584761	gene:17587730	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.	0.808
STY0753	STY0752	gene:17584762	gene:17584761	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	0.999
STY0753	STY0754	gene:17584762	gene:17584763	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	0.999
STY0753	STY1815	gene:17584762	gene:17585747	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	0.800
STY0753	STY3511	gene:17584762	gene:17587361	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap.	0.800
STY0753	STY3874	gene:17584762	gene:17587730	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.	0.808
STY0754	STY0752	gene:17584763	gene:17584761	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	0.999
STY0754	STY0753	gene:17584763	gene:17584762	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	0.999
STY0754	STY1815	gene:17584763	gene:17585747	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	0.800
STY0754	STY3511	gene:17584763	gene:17587361	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap.	0.800
STY0754	STY3874	gene:17584763	gene:17587730	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.	0.802
STY1815	STY0752	gene:17585747	gene:17584761	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	Conserved hypothetical protein; Orthologue of E. coli YBGJ_ECOLI; Fasta hit to YBGJ_ECOLI (218 aa), 86% identity in 218 aa overlap.	0.800
STY1815	STY0753	gene:17585747	gene:17584762	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap.	0.800
STY1815	STY0754	gene:17585747	gene:17584763	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	0.800
STY1815	STY3511	gene:17585747	gene:17587361	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap.	0.944
STY1815	STY3874	gene:17585747	gene:17587730	NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.	Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.	0.966

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