STRINGSTRING
STY1242 STY1242 STY1785 STY1785 STY2439 STY2439 STY2441 STY2441 STY2442 STY2442 STY2667 STY2667 STY2670 STY2670 STY3436 STY3436 STY3437 STY3437 STY3438 STY3438 STY3925 STY3925 STY4004 STY4004
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STY1242PTS system, glucose-specific IIBC component; Fasta hit to PTOA_ECOLI (530 aa), 37% identity in 513 aa overlap; Orthologue of E. coli ptsG (PTGB_ECOLI); Fasta hit to PTGB_ECOLI (477 aa), 97% identity in 476 aa overlap. (477 aa)
STY17856-phosphofructokinase isozyme; Fasta hit to K1PF_ECOLI (312 aa), 31% identity in 311 aa overlap; Orthologue of E. coli pfkB (K6P2_ECOLI); Fasta hit to K6P2_ECOLI (309 aa), 93% identity in 308 aa overlap; Belongs to the carbohydrate kinase PfkB family. (310 aa)
STY2439PTS system, fructose-specific IIBC component; Fasta hit to PTVB_ECOLI (485 aa), 34% identity in 478 aa overlap; Orthologue of E. coli fruA (PTFB_ECOLI); Fasta hit to PTFB_ECOLI (563 aa), 94% identity in 507 aa overlap. (562 aa)
STY24411-phosphofructokinase; Fasta hit to K6P2_ECOLI (309 aa), 31% identity in 310 aa overlap; Orthologue of E. coli fruK (K1PF_ECOLI); Fasta hit to K1PF_ECOLI (312 aa), 98% identity in 312 aa overlap; Belongs to the carbohydrate kinase PfkB family. (312 aa)
STY2442Pts system, fructose-specific IIA/FPR component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport. (376 aa)
STY2667Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. (85 aa)
STY2670Pts system, glucose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. (169 aa)
STY3436Possible carbohydrate kinase; Similar to Bacillus subtilis 1-phosphofructokinase fruk or fruB SW:K1PF_BACSU (O31714) (303 aa) fasta scores: E(): 9.9e-28, 31.8% id in 305 aa; Belongs to the carbohydrate kinase PfkB family. (304 aa)
STY3437Similar to Escherichia coli PTS system, fructose-like-1 IIBC component FrvB SW:PTVB_ECOLI (P32154) (485 aa) fasta scores: E(): 0, 32.4% id in 475 aa. Note, like the example given, the predicted product of this CDS contains only one hydrophilic IIB domain. Contains possible membrane spanning hydrophobic domains; Fasta hit to PTVB_ECOLI (485 aa), 32% identity in 474 aa overlap; Paralogue of E. coli fruA (PTFB_ECOLI); Fasta hit to PTFB_ECOLI (563 aa), 42% identity in 471 aa overlap. (475 aa)
STY3438This CDS is similar to the phosphotransferase enzyme IIA and HPr (phosphoryl carrier protein) domains of PTF family sugar transport proteins, e.g. the N-terminus of Xanthomonas campestris multiphosphoryl transfer protein FruB SW:PTF1_XANCP (P45597) (837 aa) fasta scores: E(): 2.9e-22, 36.0% id in 225 aa; Paralogue of E. coli fruB (PTFA_ECOLI); Fasta hit to PTFA_ECOLI (376 aa), 36% identity in 372 aa overlap. (268 aa)
STY3925Similar to Escherichia coli PTS system, fructose-specific IIBC component SW:PTFB_ECOLI () (563 aa) fasta scores: E(): 0, 65.5% id in 458 aa. Note the product of this CDS lacks the first of the two E. coli EIIB transferase domains; Fasta hit to PTVB_ECOLI (485 aa), 35% identity in 450 aa overlap; Paralogue of E. coli fruA (PTFB_ECOLI); Fasta hit to PTFB_ECOLI (563 aa), 66% identity in 458 aa overlap. (457 aa)
STY4004Similar to Mycoplasma capricolum phosphocarrier protein ptsH SW:PTHP_MYCCA (P45611) (88 aa) fasta scores: E(): 3.3e-06, 32.9% id in 76 aa, and to Alcaligenes eutrophus phosphocarrier protein SW:PTHP_ALCEU (P23537) (89 aa) fasta scores: E(): 7.5e-06, 33.7% id in 89 aa. (89 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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