STRINGSTRING
STY0917 STY0917 STY0918 STY0918 STY2572 STY2572 STY2573 STY2573 STY2574 STY2574 STY4119 STY4119 STY4120 STY4120 STY4121 STY4121 STY4122 STY4122 yjfQ yjfQ yjfR yjfR sgaT sgaT sgaB sgaB sgaA sgaA sgaH sgaH sgaU sgaU sgaE sgaE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STY0917Possible transport protein; Similar to Escherichia coli putative transport protein SgaT sgaT SW:SGAT_ECOLI (P39301) (484 aa) fasta scores: E(): 0, 39.0% id in 431 aa, and to Mycoplasma pneumoniae sgat protein homolog SW:SGAT_MYCPN (P75291) (660 aa) fasta scores: E(): 4e-09, 29.0% id in 428 aa; Paralogue of E. coli yjfS (SGAT_ECOLI); Fasta hit to SGAT_ECOLI (484 aa), 39% identity in 431 aa overlap. (447 aa)
STY0918Similar to Escherichia coli unknown pentitol phosphotransferase enzyme ii, b component sgaB SW:PTXB_ECOLI (P39302) (101 aa) fasta scores: E(): 0.00016, 25.3% id in 99 aa, and to Borrelia burgdorferi pts system, cellobiose-specific iib component bbb06 TR:O50982 (EMBL:AE000792) (105 aa) fasta scores: E(): 0.92, 28.6% id in 105 aa. (106 aa)
STY2572Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCJ21.17C TR:Q9S1Z0 (EMBL:AL109747) (516 aa) fasta scores: E(): 0, 47.3% id in 457 aa and Escherichia coli putative transport protein SgaT sgaT SW:SGAT_ECOLI (P39301) (484 aa) fasta scores: E(): 0, 27.6% id in 460 aa. Contains hydrophobic, probable membrane-spanning regions. (463 aa)
STY2573Similar to Escherichia coli unknown pentitol phosphotransferase enzyme II, B component sgaB SW:PTXB_ECOLI (P39302) (101 aa) fasta scores: E(): 0.0058, 28.7% id in 87 aa, and to the C-termini of pts system proteins e.g. Escherichia coli pts system, mannitol cmtA SW:PTYC_ECOLI (P32059) (462 aa) fasta scores: E(): 0.061, 30.9% id in 81 aa. (90 aa)
STY2574Putative sugar phosphotransferase component II A; Fasta hit to PTYA_ECOLI (147 aa), 41% identity in 146 aa overlap; Paralogue of E. coli ptxA (PTXA_ECOLI); Fasta hit to PTXA_ECOLI (154 aa), 40% identity in 140 aa overlap. (147 aa)
STY4119Putative sugar isomerase; Similar to Salmonella typhimurium L-ribulose-5-phosphate 4-epimerase araD SW:ARAD_SALTY (P06190) (231 aa) fasta scores: E(): 0, 76.2% id in 231 aa; Fasta hit to SGAE_ECOLI (228 aa), 63% identity in 230 aa overlap; Fasta hit to ARAD_ECOLI (231 aa), 77% identity in 231 aa overlap; Orthologue of E. coli yiaS (SGBE_ECOLI); Fasta hit to SGBE_ECOLI (231 aa), 93% identity in 231 aa overlap. (231 aa)
STY4120Putative sugar-phosphate isomerase; Fasta hit to SGAU_ECOLI (284 aa), 59% identity in 279 aa overlap; Orthologue of E. coli yiaR (SGBU_ECOLI); Fasta hit to SGBU_ECOLI (286 aa), 91% identity in 286 aa overlap. (286 aa)
STY4121Similar to Methylomonas aminofaciens hexulose-6-phosphate synthase hps SW:HUMS_METAM (Q48907) (208 aa) fasta scores: E(): 5.9e-17, 34.6% id in 205 aa; Fasta hit to SGAH_ECOLI (216 aa), 45% identity in 216 aa overlap; Orthologue of E. coli yiaQ (SGBH_ECOLI); Fasta hit to SGBH_ECOLI (220 aa), 90% identity in 220 aa overlap. (220 aa)
STY4122Putative L-xylulose kinase; Orthologue of E. coli lyxK (LYXK_ECOLI); Fasta hit to LYXK_ECOLI (498 aa), 86% identity in 498 aa overlap. (498 aa)
yjfQProbable transcriptional regulator; Represses ulaG and the ulaABCDEF operon. (251 aa)
yjfRConserved hypothetical protein; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family. (354 aa)
sgaTPutative transport protein SgaT; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (476 aa)
sgaBPutative PTS system IIB protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (101 aa)
sgaAProbable sugar phosphotransferase; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (154 aa)
sgaHPutative hexulose-6-phosphate synthase; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization. Belongs to the HPS/KGPDC family. KGPDC subfamily. (216 aa)
sgaUConserved hypothetical protein; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the L-ribulose-5-phosphate 3-epimerase family. (284 aa)
sgaEProbable class II aldolase; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization. (228 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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