STRINGSTRING
STY0155 STY0155 STY0182 STY0182 STY0189 STY0189 STY0197 STY0197 STY0233 STY0233 STY0262 STY0262 yaeP yaeP STY0264 STY0264 STY0265 STY0265 STY0266 STY0266 STY0271 STY0271 STY0279 STY0279 STY0363 STY0363 STY0364 STY0364 STY0365 STY0365 sbmA sbmA yaiW yaiW STY0423 STY0423 STY0451 STY0451 STY0487 STY0487 STY0516 STY0516 STY0517 STY0517 STY0522 STY0522 STY0613 STY0613 STY0726 STY0726 STY0789 STY0789 STY0860 STY0860 STY0861 STY0861 ompX ompX ybiP ybiP STY0928 STY0928 STY0991 STY0991 STY0994 STY0994 STY0995 STY0995 mukB mukB STY1002 STY1002 STY1080 STY1080 STY1090 STY1090 STY1091 STY1091 STY1094 STY1094 STY1097 STY1097 STY1102 STY1102 STY1173 STY1173 STY1174 STY1174 STY1175 STY1175 STY1186 STY1186 STY1199 STY1199 STY1202 STY1202 STY1245 STY1245 STY1246 STY1246 STY1247 STY1247 STY1250 STY1250 STY1252 STY1252 STY1299 STY1299 STY1311 STY1311 STY1315 STY1315 ispZ ispZ STY1317 STY1317 STY1318 STY1318 STY1319 STY1319 STY1342 STY1342 STY1343 STY1343 STY1378 STY1378 STY1383 STY1383 STY1402 STY1402 STY1423 STY1423 STY1424 STY1424 STY1425 STY1425 STY1544 STY1544 STY1545 STY1545 STY1558 STY1558 STY1560 STY1560 STY1561 STY1561 STY1590 STY1590 STY1646 STY1646 STY1649 STY1649 STY1652 STY1652 STY1661 STY1661 STY1662 STY1662 STY1745 STY1745 lppB lppB STY1788 STY1788 STY1790 STY1790 STY1805 STY1805 STY1830 STY1830 STY1949 STY1949 STY1953 STY1953 STY2078 STY2078 STY2079 STY2079 STY2080 STY2080 STY2081 STY2081 STY2086 STY2086 STY2115 STY2115 STY2116 STY2116 STY2121 STY2121 STY2145 STY2145 STY2156 STY2156 STY2157 STY2157 STY2172 STY2172 STY2173 STY2173 STY2174 STY2174 STY2190 STY2190 ompS1 ompS1 STY2265 STY2265 STY2277 STY2277 STY2333 STY2333 insB insB STY2420 STY2420 STY2488 STY2488 ompC ompC STY2494 STY2494 STY2495 STY2495 rcsC rcsC STY2563 STY2563 STY2565 STY2565 STY2611 STY2611 STY2622 STY2622 STY2684 STY2684 STY2713 STY2713 STY2722 STY2722 STY2736 STY2736 STY2781 STY2781 STY2846 STY2846 STY2920 STY2920 STY2923 STY2923 STY2924 STY2924 STY2925 STY2925 iap iap STY3123 STY3123 STY3216 STY3216 STY3258 STY3258 STY3262 STY3262 STY3263 STY3263 STY3264 STY3264 STY3406 STY3406 STY3407 STY3407 STY3408 STY3408 STY3409 STY3409 STY3410 STY3410 STY3411 STY3411 STY3460 STY3460 STY3485 STY3485 STY3527 STY3527 STY3542 STY3542 STY3543 STY3543 STY3544 STY3544 STY3545 STY3545 STY3546 STY3546 STY3546a STY3546a STY3746 STY3746 STY3777 STY3777 STY3782 STY3782 STY3787 STY3787 STY3788 STY3788 STY3862 STY3862 STY3885 STY3885 STY3899 STY3899 STY3900 STY3900 STY3906 STY3906 STY3968 STY3968 STY4045 STY4045 STY4124 STY4124 insB-2 insB-2 STY4135 STY4135 STY4155 STY4155 yhjJ yhjJ STY4193 STY4193 STY4194 STY4194 STY4195 STY4195 STY4212 STY4212 STY4213 STY4213 STY4237 STY4237 yrfF yrfF damX damX yhfC yhfC STY4406 STY4406 STY4440 STY4440 STY4441 STY4441 yjeI yjeI yjeP yjeP yjeT yjeT yjfN yjfN yjfO yjfO yjfP yjfP yjfY yjfY ytfB ytfB ytfJ ytfJ ytfK ytfK mdoB mdoB smp smp trpR trpR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STY0155Conserved hypothetical protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family. (142 aa)
STY0182Similar to Escherichia coli hypothetical 13.9 kda protein in acnb-sped intergenic region yacl SW:YACL_ECOLI (P45567; P75653) fasta scores: E(): 0, 84.9% id in 119 aa, and to Haemophilus influenzae hypothetical protein hi1724 hi1724 SW:YACL_HAEIN (P44297) fasta scores: E(): 4.9e-13, 38.0% id in 121 aa; Belongs to the UPF0231 family. (120 aa)
STY0189Conserved hypothetical protein; Orthologue of E. coli yacC (YACC_ECOLI); Fasta hit to YACC_ECOLI (115 aa), 96% identity in 115 aa overlap. (115 aa)
STY0197Conserved hypothetical protein; Similar to Staphylococcus epidermidis IcaB icaB TR:Q54067 (EMBL:U43366) (289 aa) fasta scores: E(): 3.3e-13, 27.8% id in 245 aa, and to Escherichia coli ShF shF TR:Q9X692 (EMBL:AF134403) (280 aa) fasta scores: E(): 9.7e-07, 26.1% id in 257 aa, and to Shigella flexneri Shf1 shf1 TR:P72436 (EMBL:U61977) (132 aa) fasta scores: E(): 1.7e-06, 31.9% id in 113 aa; Orthologue of E. coli yadE (YADE_ECOLI); Fasta hit to YADE_ECOLI (409 aa), 81% identity in 406 aa overlap. (407 aa)
STY0233Conserved hypothetical protein; Orthologue of E. coli yaeH (YAEH_ECOLI); Fasta hit to YAEH_ECOLI (128 aa), 95% identity in 128 aa overlap; Belongs to the UPF0325 family. (128 aa)
STY0262ROF protein; Orthologue of E. coli yaeO (ROF_ECOLI); Fasta hit to ROF_ECOLI (84 aa), 81% identity in 84 aa overlap. (84 aa)
yaePSimilar to Escherichia coli hypothetical 7.2 kDa protein in mesj-cutf intergenic region yaeP SW:YAEP_ECOLI (P52099) (66 aa) fasta scores: E(): 1.2e-23, 92.4% id in 66 aa; Belongs to the UPF0253 family. (72 aa)
STY0264Conserved hypothetical protein; Orthologue of E. coli yaeQ (YAEQ_ECOLI); Fasta hit to YAEQ_ECOLI (181 aa), 89% identity in 181 aa overlap. (181 aa)
STY0265Putative release factor; Similar to Escherichia coli hypothetical 15.6 kDa protein in mesj-cutf intergenic region yaeJ SW:YAEJ_ECOLI (P40711) (140 aa) fasta scores: E(): 0, 84.6% id in 136 aa, and to Pseudomonas putida hypothetical 15.2 kDa protein in pcaj 3'region SW:YAEJ_PSEPU (P45388) (137 aa) fasta scores: E(): 9.5e-27, 57.0% id in 135 aa and to Salmonella typhimurium peptide chain release factor 2 prfB SW:RF2_SALTY (P28353) (365 aa) fasta scores: E(): 0.45, 29.6% id in 108 aa; Orthologue of E. coli yaeJ (YAEJ_ECOLI); Fasta hit to YAEJ_ECOLI (140 aa), 85% identity in 136 aa overlap. (140 aa)
STY0266Copper homeostasis protein CutF precursor (lipoprotein nlpE); Orthologue of E. coli CutF (CUTF_ECOLI); Fasta hit to CUTF_ECOLI (236 aa), 76% identity in 232 aa overlap. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (233 aa)
STY0271RcsF protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. (134 aa)
STY0279Conserved hypothetical protein; Orthologue of E. coli yafD (YAFD_ECOLI); Fasta hit to YAFD_ECOLI (259 aa), 97% identity in 259 aa overlap. (259 aa)
STY0363Conserved hypothetical protein; Displays esterase activity toward pNP-butyrate. (414 aa)
STY0364Curlin genes transcriptional activator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (133 aa)
STY0365Outer membrane pore protein E precursor; Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes; Belongs to the Gram-negative porin family. (350 aa)
sbmASbmA protein; Similar to Escherichia coli SbmA protein sbmA SW:SBMA_ECOLI (P24212; P75702; P71313) (406 aa) fasta scores: E(): 0, 91.6% id in 406 aa, and to Rhizobium meliloti bacteroid development protein BacA bacA SW:BACA_RHIME (Q08120) (420 aa) fasta scores: E(): 0, 64.1% id in 409 aa, and to membrane domains of e.g. Escherichia coli hypothetical ABC transporter ATP-binding protein in pqql-hipa intergenic region yddA SW:YDDA_ECOLI (P31826; P76133; P76876) (561 aa) fasta scores: E(): 1.5e-05, 24.7% id in 365 aa; Orthologue of E. coli sbmA (SBMA_ECOLI); Fasta hit to SBMA_ECOLI (406 aa [...] (406 aa)
yaiWPutative lipoprotein; Similar to Escherichia coli hypothetical 40.4 kDa protein in sbma-ddla intergenic region yaiW SW:YAIW_ECOLI (P77562) (364 aa) fasta scores: E(): 0, 85.1% id in 362 aa, and to Chlorobium vibrioforme hypothetical 42.0 kDa protein TR:O50315 (EMBL:Z83933) (368 aa) fasta scores: E(): 3.7e-29, 30.6% id in 373 aa; Orthologue of E. coli YAIW_ECOLI; Fasta hit to YAIW_ECOLI (364 aa), 85% identity in 362 aa overlap. (364 aa)
STY0423AroM protein; Orthologue of E. coli aroM (AROM_ECOLI); Fasta hit to AROM_ECOLI (225 aa), 77% identity in 225 aa overlap. (225 aa)
STY0451Nucleoside-specific channel-forming protein tsx precursor; Functions as substrate-specific channel for nucleosides and deoxynucleosides; Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. (287 aa)
STY0487Putative lipoprotein; Orthologue of E. coli yajG (YAJG_ECOLI); Fasta hit to YAJG_ECOLI (192 aa), 90% identity in 192 aa overlap. (192 aa)
STY0516Haemolysin expression modulating protein; Fasta hit to YDGT_ECOLI (71 aa), 38% identity in 71 aa overlap; Orthologue of E. coli hha (HHA_ECOLI); Fasta hit to HHA_ECOLI (72 aa), 99% identity in 72 aa overlap. (72 aa)
STY0517Conserved hypothetical protein; Orthologue of E. coli ybaJ (YBAJ_ECOLI); Fasta hit to YBAJ_ECOLI (124 aa), 95% identity in 124 aa overlap. (124 aa)
STY0522Integral membrane protein AefA; Orthologue of E. coli AEFA_ECOLI; Fasta hit to AEFA_ECOLI (1120 aa), 89% identity in 1118 aa overlap. (1120 aa)
STY0613Similar to Escherichia coli hypothetical 9.1 kDa protein in eaeh-beta intergenic region. hypothetical 8.5 kda protein in eaeh-beta intergenic region precursor SW:YKGI_ECOLI () (83 aa) fasta scores: E(): 3.8e-12, 53.8% id in 78 aa, and to N-terminus of Escherichia coli, Klebsiella pneumoniae, beta-lactamase shv-2 precursor SW:BLA2_ECOLI () (286 aa) fasta scores: E(): 7, 36.1% id in 61 aa. Contains probable N-terminal signal sequence; Fasta hit to YHCN_ECOLI (87 aa), 32% identity in 78 aa overlap; Fasta hit to YCFR_ECOLI (85 aa), 32% identity in 85 aa overlap; Fasta hit to YJFN_ECOLI (10 [...] (78 aa)
STY0726Putative lipoprotein; Orthologue of E. coli YBFN_ECOLI; Fasta hit to YBFN_ECOLI (108 aa), 84% identity in 107 aa overlap; Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (110 aa)
STY0789Putative membrane protein; Similar to Escherichia coli 10.9 kDa protein in cydb-tolq intergenic region SW:YBGE_ECOLI (P37343) (97 aa) fasta scores: E(): 0, 86.7% id in 90 aa, and to Vibrio cholerae hypothetical protein Vc1841 vc1841 TR:Q9KR06 (EMBL:AE004260) (105 aa) fasta scores: E(): 1.2e-09, 38.5% id in 78 aa. (93 aa)
STY0860Putative exported protein; Fasta hit to YHCN_ECOLI (87 aa), 48% identity in 88 aa overlap; Fasta hit to YCFR_ECOLI (85 aa), 45% identity in 86 aa overlap; Fasta hit to YAHO_ECOLI (91 aa), 32% identity in 91 aa overlap; Orthologue of E. coli ybiJ (YBIJ_ECOLI); Fasta hit to YBIJ_ECOLI (86 aa), 80% identity in 86 aa overlap. Contains probable N-terminal signal sequence. (86 aa)
STY0861Hypothetical protein; No database matches. (46 aa)
ompXSimilar to Escherichia coli outer membrane protein x precursor ompX SW:OMPX_ECOLI (P36546) (171 aa) fasta scores: E(): 0, 91.2% id in 171 aa, and to Yersinia enterocolitica attachment invasion locus protein precursor aiL SW:AIL_YEREN (P16454) (178 aa) fasta scores: E(): 6.1e-22, 43.3% id in 180 aa; Orthologue of E. coli ompX (OMPX_ECOLI); Fasta hit to OMPX_ECOLI (171 aa), 91% identity in 171 aa overlap. (171 aa)
ybiPPutative membrane protein; Similar to Escherichia coli hypothetical 59.7 kDa protein in ompx-moeb intergenic region ybiP SW:YBIP_ECOLI (P75785) (527 aa) fasta scores: E(): 0, 83.8% id in 526 aa; Orthologue of E. coli YBIP_ECOLI; Fasta hit to YBIP_ECOLI (527 aa), 84% identity in 526 aa overlap. (526 aa)
STY0928Putative oxidoreductase; Similar to Escherichia coli from bases 898938 to 910366 TR:P75821 (EMBL:AE000188) (349 aa) fasta scores: E(): 0, 93.2% id in 337 aa, and to Yersinia pestis similar to ecae000188_9 escherichia coli k-12 mg1655 TR:Q9ZC81 (EMBL:AL031866) (338 aa) fasta scores: E(): 0, 43.8% id in 331 aa, and to Homo sapiens NAD(P)-dependent steroid dehydrogenase-like protein SW:NSDL_HUMAN (Q15738) (373 aa) fasta scores: E(): 2.3e-15, 25.4% id in 339 aa, and to Mus musculus NAD(P)-dependent steroid dehydrogenase-like protein SW:NSDL_MOUSE (Q9R1J0) (362 aa) fasta scores: E(): 2e-14, [...] (337 aa)
STY0991Conserved hypothetical protein; Orthologue of E. coli P75845; Fasta hit to P75845 (297 aa), 91% identity in 297 aa overlap. (297 aa)
STY0994Killing factor KicB; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa)
STY0995KicA protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. (225 aa)
mukBCell division protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1488 aa)
STY1002Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. (363 aa)
STY1080Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (181 aa)
STY1090Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. (150 aa)
STY1091Outer membrane protein A; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. (350 aa)
STY1094Conserved hypothetical protein; Orthologue of E. coli YCCR_ECOLI; Fasta hit to YCCR_ECOLI (209 aa), 75% identity in 199 aa overlap. (201 aa)
STY1097Helicase IV (75 kD helicase); Orthologue of E. coli helD (HELD_ECOLI); Fasta hit to HELD_ECOLI (684 aa), 84% identity in 684 aa overlap. (684 aa)
STY1102Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. (105 aa)
STY1173Conserved hypothetical protein; Orthologue of E. coli YCDX_ECOLI; Fasta hit to YCDX_ECOLI (245 aa), 89% identity in 245 aa overlap; Belongs to the PHP family. (245 aa)
STY1174Conserved hypothetical protein; Orthologue of E. coli YCDY_ECOLI; Fasta hit to YCDY_ECOLI (184 aa), 86% identity in 184 aa overlap. (184 aa)
STY1175Putative membrane protein; Fasta hit to YAHC_ECOLI (165 aa), 30% identity in 156 aa overlap; Orthologue of E. coli YCDZ_ECOLI; Fasta hit to YCDZ_ECOLI (179 aa), 84% identity in 179 aa overlap. (176 aa)
STY1186Glucans biosynthesis protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (384 aa)
STY1199Conserved hypothetical protein; Orthologue of E. coli YCEP_ECOLI; Fasta hit to YCEP_ECOLI (84 aa), 93% identity in 84 aa overlap. (85 aa)
STY1202Conserved hypothetical protein; Orthologue of E. coli yceB (YCEB_ECOLI); Fasta hit to YCEB_ECOLI (186 aa), 88% identity in 184 aa overlap. Note difference in translational start site. (208 aa)
STY1245Similar to Gallus gallus protein kinase C inhibitor chpkcI TR:BAA93455 (EMBL:AB026676) (126 aa) fasta scores: E(): 2.3e-19, 49.1% id in 108 aa; Orthologue of E. coli ycfF (YCFF_ECOLI); Fasta hit to YCFF_ECOLI (119 aa), 98% identity in 119 aa overlap. (119 aa)
STY1246Putative lipoprotein; Orthologue of E. coli YCFL_ECOLI; Fasta hit to YCFL_ECOLI (125 aa), 81% identity in 125 aa overlap. (124 aa)
STY1247Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. (212 aa)
STY1250Conserved hypothetical protein; Orthologue of E. coli YCFP_ECOLI; Fasta hit to YCFP_ECOLI (199 aa), 94% identity in 180 aa overlap; Belongs to the UPF0227 family. (180 aa)
STY1252Putative secreted protein; Orthologue of E. coli ycfJ (YCFJ_ECOLI); Fasta hit to YCFJ_ECOLI (179 aa), 95% identity in 178 aa overlap. (179 aa)
STY1299DNA-binding protein (histone-like protein Hlp-II); A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome. As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes. A subset of genes are repressed by H-NS in association with other proteins (By similarity). (137 aa)
STY1311Similar to Haemophilus influenzae hypothetical protein Hi1450 hi1450 SW:YCIU_HAEIN (P44199) (107 aa) fasta scores: E(): 3.1e-19, 46.1% id in 102 aa; Orthologue of E. coli YCIU_ECOLI; Fasta hit to YCIU_ECOLI (109 aa), 94% identity in 109 aa overlap; Belongs to the UPF0263 family. (109 aa)
STY1315Putative acyl-coA hydrolase; Catalyzes the hydrolysis of the thioester bond in palmitoyl- CoA and malonyl-CoA. (133 aa)
ispZPutative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa)
STY1317Putative membrane protein; Similar to Escherichia coli YciC protein TR:BAA14787 (EMBL:D90763) (247 aa) fasta scores: E(): 0, 86.6% id in 247 aa, and to Buchnera aphidicola hypothetical protein BU276 homolog SW:Y276_BUCAP (P42396) (247 aa) fasta scores: E(): 7.5e-21, 29.5% id in 244 aa. (247 aa)
STY1318Conserved hypothetical protein; Similar to Acinetobacter calcoaceticus putative ferredoxin SW:FERX_ACICA (P31004) (121 aa) fasta scores: E(): 1.4e-18, 48.6% id in 107 aa; Orthologue of E. coli YKGJ_ECOLI; Fasta hit to YKGJ_ECOLI (109 aa), 74% identity in 109 aa overlap. (134 aa)
STY1319Putative outer membrane protein; Orthologue of E. coli yciD (OMPW_ECOLI); Fasta hit to OMPW_ECOLI (212 aa), 89% identity in 212 aa overlap. (212 aa)
STY1342Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa)
STY1343Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa)
STY1378Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] (513 aa)
STY1383Conserved hypothetical protein; Orthologue of E. coli YCJI_ECOLI; Fasta hit to YCJI_ECOLI (262 aa), 91% identity in 242 aa overlap. (242 aa)
STY1402Putative membrane protein; Orthologue of E. coli YNAJ_ECOLI; Fasta hit to YNAJ_ECOLI (85 aa), 88% identity in 84 aa overlap. (84 aa)
STY1423Putative exported protein; Orthologue of E. coli YDBH_ECOLI; Fasta hit to YDBH_ECOLI (879 aa), 79% identity in 878 aa overlap. (878 aa)
STY1424Putative lipoprotein; Orthologue of E. coli YNBE_ECOLI; Fasta hit to YNBE_ECOLI (61 aa), 75% identity in 63 aa overlap. (63 aa)
STY1425Putative secreted protein; Orthologue of E. coli YDBL_ECOLI; Fasta hit to YDBL_ECOLI (108 aa), 70% identity in 107 aa overlap. (107 aa)
STY1544Putative membrane protein; Orthologue of E. coli ydeF (YDEE_ECOLI); Fasta hit to YDEE_ECOLI (395 aa), 77% identity in 395 aa overlap. (395 aa)
STY1545Putative periplasmic protein; Orthologue of E. coli ydeI (YDEI_ECOLI); Fasta hit to YDEI_ECOLI (130 aa), 80% identity in 107 aa overlap. (118 aa)
STY1558Putative membrane protein; Similar to Synechocystis sp hypothetical 12.0 kDa protein Sll0793 sll0793 SW:Y793_SYNY3 (Q55939) (108 aa) fasta scores: E(): 3.2e-15, 46.6% id in 103 aa; Orthologue of E. coli YNFA_ECOLI; Fasta hit to YNFA_ECOLI (108 aa), 88% identity in 108 aa overlap. (108 aa)
STY1560Putative secreted protein; Orthologue of E. coli YNFB_ECOLI; Fasta hit to YNFB_ECOLI (113 aa), 81% identity in 113 aa overlap; Belongs to the UPF0482 family. (113 aa)
STY1561Spermidine N1-acetyltransferase; Orthologue of E. coli speG (ATDA_ECOLI); Fasta hit to ATDA_ECOLI (185 aa), 91% identity in 184 aa overlap. (186 aa)
STY1590Putative exported protein; Orthologue of E. coli YDGH_ECOLI; Fasta hit to YDGH_ECOLI (314 aa), 90% identity in 314 aa overlap. (314 aa)
STY1646Putative membrane protein; Orthologue of E. coli YDGC_ECOLI; Fasta hit to YDGC_ECOLI (111 aa), 81% identity in 111 aa overlap. (111 aa)
STY1649Outer membrane protein; Forms pores that allow passive diffusion of small molecules across the outer membrane. (383 aa)
STY1652DNA replication terminus site-binding protein; Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence; Belongs to the Tus family. (309 aa)
STY1661Conserved hypothetical protein; Binds to H-NS and modified the range of genes it silences; H- NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer. Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity). The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity); Belongs to the Hha/YmoA/Cnu family. (71 aa)
STY1662Putative membrane protein; Orthologue of E. coli YDGK_ECOLI; Fasta hit to YDGK_ECOLI (146 aa), 83% identity in 146 aa overlap. (146 aa)
STY1745Major outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane; Belongs to the Lpp family. (78 aa)
lppBMajor outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane; Belongs to the Lpp family. (79 aa)
STY1788Putative membrane protein; Similar to Escherichia coli hypothetical 20.4 kDa protein in pfkB-cedA intergenic region yniB SW:YNIB_ECOLI (P76208) (178 aa) fasta scores: E(): 0, 83.7% id in 178 aa, and to Yersinia pestis putative yfeABCD regulator YfeE yfeE SW:YFEE_YERPE (Q56956) (184 aa) fasta scores: E(): 0, 67.4% id in 181 aa; Orthologue of E. coli YNIB_ECOLI; Fasta hit to YNIB_ECOLI (178 aa), 84% identity in 178 aa overlap. (178 aa)
STY1790Similar to Escherichia coli hypothetical 22.8 kDa protein in pfkb-ceda intergenic region precursor ydjM SW:YDJM_ECOLI (P76209) (200 aa) fasta scores: E(): 0, 85.9% id in 199 aa, and to Bacillus subtilis hypothetical 17.6 kDa protein in sspj-secg intergenic region precursor yvsG SW:YVSG_BACSU (O32205) (160 aa) fasta scores: E(): 4.3e-10, 33.3% id in 156 aa. (199 aa)
STY1805Putative exported protein; Similar to Escherichia coli spheroplast protein Y precursor spy SW:SPY_ECOLI (P77754) (161 aa) fasta scores: E(): 0, 88.2% id in 161 aa, and to Escherichia coli periplasmic protein CpxP precursor. periplasmic protein CpxP precursor SW:CPXP_ECOLI () (166 aa) fasta scores: E(): 3.1e-08, 30.4% id in 148 aa; Fasta hit to CPXP_ECOLI (166 aa), 30% identity in 148 aa overlap. (161 aa)
STY1830Putative outer membrane protein; Similar to Escherichia coli hypothetical 27.8 kDa protein in gapA-rnd intergenic region precursor. protein yeaF precursor SW:YEAF_ECOLI () (248 aa) fasta scores: E(): 0, 83.9% id in 248 aa, and to Escherichia coli hypothetical 27.4 kDa protein in avtA-selB intergenic region precursor yiaT SW:YIAT_ECOLI (P37681) (246 aa) fasta scores: E(): 0, 41.6% id in 243 aa, and to Vibrio cholerae outer membrane protein ompV precursor. outer membrane protein ompV precursor SW:OMPV_VIBCH () (257 aa) fasta scores: E(): 3e-09, 23.4% id in 209 aa. (248 aa)
STY1949Putative lipoprotein; Similar to Escherichia coli from bases 1886020 to 1896397 TR:P76255 (EMBL:AE000275) (193 aa) fasta scores: E(): 0, 90.2% id in 193 aa, and to Escherichia coli outer membrane protein SlP precursor slP SW:SLP_ECOLI (P37194) (188 aa) fasta scores: E(): 2.8e-22, 43.1% id in 174 aa. (193 aa)
STY1953Similar to Escherichia coli hypothetical 6.6 kDa protein in fadD-pabB intergenic region yoaH SW:YOAH_ECOLI (P76260) (59 aa) fasta scores: E(): 1.5e-18, 89.8% id in 59 aa, and to Salmonella typhimurium hypothetical protein in fadD-pabB intergenic region SW:YOAH_SALTY (P56505) (42 aa) fasta scores: E(): 4.7e-13, 100.0% id in 42 aa, and to Haemophilus influenzae hypothetical protein Hi1434.2 hi1434.2 SW:YOAH_HAEIN (P56507) (52 aa) fasta scores: E(): 1.2e-06, 65.1% id in 43 aa; Belongs to the UPF0181 family. (59 aa)
STY2078Hypothetical protein; Unknown function. (38 aa)
STY2079Putative exported protein; Orthologue of E. coli P76277; Fasta hit to P76277 (113 aa), 81% identity in 112 aa overlap; Unknown function. Contains a probable N-terminal signal sequence. (117 aa)
STY2080Putative cation transporter; Similar to Pseudomonas syringae copper resistance protein D copD SW:COPD_PSESM (P12377) (310 aa) fasta scores: E(): 1.3e-12, 28.4% id in 299 aa and Xanthomonas campestris juglandis copper-resistance protein TR:Q56798 (EMBL:L19222) (307 aa) fasta scores: E(): 2e-12, 26.3% id in 304 aa. Contains hydrophobic, possible membrane-spanning regions; Orthologue of E. coli P76278; Fasta hit to P76278 (290 aa), 65% identity in 290 aa overlap. (291 aa)
STY2081Similar to Xanthomonas campestris copper resistance protein C precursor SW:COPC_XANCJ (Q56797) (127 aa) fasta scores: E(): 1.6e-09, 34.7% id in 118 aa, and to Escherichia coli copper resistance protein C precursor pcoC SW:COPC_ECOLI (Q47454) (126 aa) fasta scores: E(): 2.9e-08, 41.1% id in 112 aa. Contains a probable N-terminal signal sequence; Orthologue of E. coli YOBA_ECOLI; Fasta hit to YOBA_ECOLI (124 aa), 73% identity in 124 aa overlap. (126 aa)
STY2086Similar to Yersinia enterocolitica hypothetical protein SW:YEBE_YEREN (P45462) (139 aa) fasta scores: E(): 0, 63.5% id in 137 aa. Also shows weaker similarity to Neisseria meningitidis (serogroup A) hypothetical protein NMA2201 TR:Q9JSP5 (204 aa) fasta scores: E(): 7.1e-07, 30.0% id in 210 aa overlap and Neisseria meningitidis (serogroup B) hypothetical protein NMB0286 TR:Q9K182 (204 aa) fasta scores: E(): 1.5e-06, 29.5% id in 210 aa overlap; Orthologue of E. coli yebE (YEBE_ECOLI); Fasta hit to YEBE_ECOLI (219 aa), 87% identity in 217 aa overlap. (219 aa)
STY2115Putative copper homeostasis protein; Participates in the control of copper homeostasis. (259 aa)
STY2116Similar to Haemophilus influenzae hypothetical protein Hi1582/1581 hi1582/1581 SW:YECM_HAEIN (P44262; P44261) (191 aa) fasta scores: E(): 2.5e-21, 38.0% id in 184 aa; Orthologue of E. coli YECM_ECOLI; Fasta hit to YECM_ECOLI (188 aa), 85% identity in 188 aa overlap. (189 aa)
STY2121Flagellar protein FlhE precursor; Not essential for flagellar formation and function. (130 aa)
STY2145Tyrosine-specific transport protein; Fasta hit to TNAB_ECOLI (415 aa), 32% identity in 409 aa overlap; Fasta hit to MTR_ECOLI (414 aa), 34% identity in 399 aa overlap; Orthologue of E. coli tyrP (TYRP_ECOLI); Fasta hit to TYRP_ECOLI (403 aa), 89% identity in 403 aa overlap. (403 aa)
STY2156Hypothetical protein; Unknown function. (51 aa)
STY2157Conserved hypothetical protein; Orthologue of E. coli yecF (YECF_ECOLI); Fasta hit to YECF_ECOLI (74 aa), 88% identity in 74 aa overlap. (74 aa)
STY2172Putative lipoprotein; Similar to Salmonella typhimurium hypothetical protein yedD SW:YEDD_SALTY (Q06399) (141 aa) fasta scores: E(): 0, 98.5% id in 137 aa. Contains a probable N-terminal signal sequnce; Orthologue of E. coli yedD (YEDD_ECOLI); Fasta hit to YEDD_ECOLI (137 aa), 84% identity in 137 aa overlap. (137 aa)
STY2173Putative membrane protein; Similar to Salmonella typhimurium hypothetical protein yedE SW:YEDE_SALTY (Q06400) (401 aa) fasta scores: E(): 0, 99.3% id in 401 aa. Contains hydrophobic, probable membrane-spanning regions; Orthologue of E. coli yedE (YEDE_ECOLI); Fasta hit to YEDE_ECOLI (401 aa), 92% identity in 399 aa overlap. (421 aa)
STY2174Conserved hypothetical protein; Fasta hit to YHHP_ECOLI (81 aa), 31% identity in 72 aa overlap; Orthologue of E. coli yedF (YEDF_ECOLI); Fasta hit to YEDF_ECOLI (77 aa), 100% identity in 77 aa overlap; Belongs to the sulfur carrier protein TusA family. (77 aa)
STY2190Colanic acid capsullar biosynthesis activation protein A; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes. (207 aa)
ompS1Outer membrane protein S1; Forms pores that allow passive diffusion of small molecules across the outer membrane. (394 aa)
STY2265Putative membrane protein; Similar to Neisseria meningitidis putative integral membrane protein NMA0079 TR:Q9JX36 (EMBL:AL162752) (375 aa) fasta scores: E(): 4.7e-20, 27.3% id in 352 aa and Neisseria meningitidis hypothetical protein NMB0188 TR:Q9K1G5 (EMBL:AE002376) (375 aa) fasta scores: E(): 6.3e-20, 27.0% id in 352 aa. N-terminal half contains hydrophobic, possible membrane-spanning regions; Orthologue of E. coli yeeA (YEEA_ECOLI); Fasta hit to YEEA_ECOLI (352 aa), 78% identity in 352 aa overlap. (352 aa)
STY2277Putative amino acid transporter protein; Fasta hit to YCJJ_ECOLI (461 aa), 64% identity in 446 aa overlap; Orthologue of E. coli yeeF (YEEF_ECOLI); Fasta hit to YEEF_ECOLI (454 aa), 99% identity in 452 aa overlap. (454 aa)
STY2333Putative outer membrane assembly protein; Orthologue of E. coli yegA (ASMA_ECOLI); Fasta hit to ASMA_ECOLI (617 aa), 76% identity in 618 aa overlap. Contains probable N-terminal signal sequence. (618 aa)
insBSimilar to Escherichia coli insertion element IS1 protein InsB insB SW:INSB_ECOLI (P03830; P77707) (167 aa) fasta scores: E(): 0, 97.0% id in 167 aa. (167 aa)
STY2420Insertion element IS1 protein InsA; Absolutely required for transposition of IS1. (91 aa)
STY2488Ecotin precursor; General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. (164 aa)
ompCOuter membrane protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. (378 aa)
STY2494Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (889 aa)
STY2495Regulator of capsule synthesis B component; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (216 aa)
rcsCSensor protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa)
STY2563Putative sodium/sulphate transporter; Similar to e.g. Chlamydomonas reinhardtii putative sulphur deprivation response regulator sac1 SW:SAC1_CHLRE (Q39593) (585 aa) fasta scores: E(): 3.7e-24, 25.8% id in 597 aa. Mutants in sac1 are unable to synthesise arylsulphatase and are defficient in sulphate uptake compared to wild type. Contains hydrophobic, probable membrane-spanning regions; Orthologue of E. coli YFBS_ECOLI; Fasta hit to YFBS_ECOLI (610 aa), 91% identity in 610 aa overlap. (608 aa)
STY2565Similar to Escherichia coli hypothetical protein yfbU SW:YFBU_ECOLI (P76492) (164 aa) fasta scores: E(): 0, 95.7% id in 164 aa and Vibrio cholerae hypothetical protein VC1871 vc1871 TR:Q9KQX6 (EMBL:AE004263) (170 aa) fasta scores: E(): 0, 64.5% id in 166 aa. Shows weaker similarity to Methanococcus jannaschii hypothetical protein MJECS11 SW:YY11_METJA (Q60310) (195 aa) fasta scores: E(): 3.3e-13, 30.5% id in 177 aa; Belongs to the UPF0304 family. (164 aa)
STY2611Conserved hypothetical protein; Orthologue of E. coli YFCL_ECOLI; Fasta hit to YFCL_ECOLI (92 aa), 86% identity in 91 aa overlap. (91 aa)
STY2622Conserved hypothetical protein; Fasta hit to YIIS_ECOLI (99 aa), 41% identity in 96 aa overlap; Orthologue of E. coli YFCZ_ECOLI; Fasta hit to YFCZ_ECOLI (94 aa), 94% identity in 94 aa overlap. (94 aa)
STY2684Putative lipoprotein; Orthologue of E. coli P76537; Fasta hit to P76537 (191 aa), 81% identity in 191 aa overlap. Contains probable N-terminal signal sequence. (191 aa)
STY2713Putative exported protein; Orthologue of E. coli YPFG_ECOLI; Fasta hit to YPFG_ECOLI (347 aa), 78% identity in 347 aa overlap. Contains probable N-terminal signal sequence. (347 aa)
STY2722Putative membrane protein; Similar to Escherichia coli similar to TR:P77259 (EMBL:D90875) (66 aa) fasta scores: E(): 1e-27, 95.5% id in 66 aa. Contains hydrophobic, possible membrane-spanning region. (66 aa)
STY2736Putative arsenate reductase (arsenical pump modifier); Fasta hit to ARSC_ECOLI (141 aa), 40% identity in 114 aa overlap; Orthologue of E. coli YFGD_ECOLI; Fasta hit to YFGD_ECOLI (119 aa), 83% identity in 119 aa overlap. (119 aa)
STY2781SseB protein; Orthologue of E. coli sseB (SSEB_ECOLI); Fasta hit to SSEB_ECOLI (261 aa), 89% identity in 261 aa overlap. (261 aa)
STY2846Conserved hypothetical protein; Orthologue of E. coli yfiM (YFIM_ECOLI); Fasta hit to YFIM_ECOLI (90 aa), 80% identity in 90 aa overlap. (107 aa)
STY2920DNA-binding protein StpA; A DNA-binding protein that acts in a fashion similar to H-NS, repressing gene transcription. A subset of H-NS/StpA-regulated genes require auxillary proteins for repression; these auxillary proteins (Hha and other similar proteins) may also modulate oligomerization of the H-NS/StpA complex (By similarity). (133 aa)
STY2923Putative membrane protein; Exports L-alanine; Belongs to the AlaE exporter family. (149 aa)
STY2924Conserved hypothetical protein; Orthologue of E. coli ygaC (YGAC_ECOLI); Fasta hit to YGAC_ECOLI (114 aa), 88% identity in 112 aa overlap. (116 aa)
STY2925Conserved hypothetical protein; Fasta hit to YQJD_ECOLI (101 aa), 40% identity in 95 aa overlap; Fasta hit to ELAB_ECOLI (101 aa), 34% identity in 96 aa overlap; Orthologue of E. coli YGAM_ECOLI; Fasta hit to YGAM_ECOLI (113 aa), 87% identity in 108 aa overlap. (108 aa)
iapAlkaline phosphatase isozyme conversion protein; Orthologue of E. coli iap (IAP_ECOLI); Fasta hit to IAP_ECOLI (345 aa), 85% identity in 344 aa overlap. (348 aa)
STY3123Possible lipoprotein; Similar to Escherichia coli hypothetical lipoprotein YgdI SW:YGDI_ECOLI (Q46924) (75 aa) fasta scores: E(): 1.7e-25, 93.2% id in 74 aa and to Escherichia coli hypothetical lipoprotein YgdR SW:YGDR_ECOLI (Q46932) (72 aa) fasta scores: E(): 6.5e-13, 59.2% id in 71 aa. Contains a possible N-terminal signal sequence and an appropriately positioned Prokaryotic membrane lipoprotein lipid attachment site. (75 aa)
STY3216Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa)
STY3258Conserved hypothetical protein; Orthologue of E. coli yggM (YGGM_ECOLI); Fasta hit to YGGM_ECOLI (335 aa), 65% identity in 333 aa overlap. Note rich in the amino acids Gln, Glu and Lys. (335 aa)
STY3262Conserved hypothetical protein; Orthologue of E. coli yggN (YGGN_ECOLI); Fasta hit to YGGN_ECOLI (239 aa), 88% identity in 239 aa overlap. (239 aa)
STY3263Conserved hypothetical protein; Orthologue of E. coli yggL (YGGL_ECOLI); Fasta hit to YGGL_ECOLI (108 aa), 96% identity in 108 aa overlap. (108 aa)
STY3264Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (239 aa)
STY3406Putative membrane protein; Fasta hit to YGHB_ECOLI (219 aa), 63% identity in 216 aa overlap; Fasta hit to DEDA_ECOLI (219 aa), 30% identity in 223 aa overlap; Orthologue of E. coli YQJA_ECOLI; Fasta hit to YQJA_ECOLI (220 aa), 95% identity in 220 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. (220 aa)
STY3407Putative exported protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. (127 aa)
STY3408Putative exported protein; Orthologue of E. coli yqjC (YQJC_ECOLI); Fasta hit to YQJC_ECOLI (127 aa), 84% identity in 122 aa overlap. Contains a possible N-terminal signal sequence and possible coiled-coils between residues 51..114. (122 aa)
STY3409Conserved hypothetical protein; Fasta hit to YGAM_ECOLI (113 aa), 41% identity in 99 aa overlap; Fasta hit to ELAB_ECOLI (101 aa), 44% identity in 101 aa overlap; Fasta hit to HNS_ECOLI (136 aa), 31% identity in 110 aa overlap; Orthologue of E. coli yqjD (YQJD_ECOLI); Fasta hit to YQJD_ECOLI (101 aa), 90% identity in 101 aa overlap. (101 aa)
STY3410Putative membrane protein; Orthologue of E. coli yqjE (YQJE_ECOLI); Fasta hit to YQJE_ECOLI (134 aa), 89% identity in 130 aa overlap. Contains possible membrane spanning hydrophobic domains. (132 aa)
STY3411Conserved hypothetical protein; Orthologue of E. coli YQJK_ECOLI; Fasta hit to YQJK_ECOLI (99 aa), 88% identity in 99 aa overlap. (99 aa)
STY3460Probable amino acid permease; Fasta hit to TNAB_ECOLI (415 aa), 54% identity in 406 aa overlap; Fasta hit to TYRP_ECOLI (403 aa), 35% identity in 401 aa overlap; Orthologue of E. coli mtr (MTR_ECOLI); Fasta hit to MTR_ECOLI (414 aa), 95% identity in 414 aa overlap. (414 aa)
STY3485Orthologue of E. coli Ner-like protein (Nlp) involved in the regulation of sugar metabolism (NLP_ECOLI); Fasta hit to NLP_ECOLI (92 aa), 87% identity in 92 aa overlap. (95 aa)
STY3527Conserved hypothetical protein; Orthologue of E. coli yhcB (YHCB_ECOLI); Fasta hit to YHCB_ECOLI (134 aa), 96% identity in 132 aa overlap. (134 aa)
STY3542Conserved hypothetical protein; Fasta hit to YCFR_ECOLI (85 aa), 34% identity in 88 aa overlap; Fasta hit to YJFN_ECOLI (100 aa), 34% identity in 93 aa overlap; Fasta hit to YAHO_ECOLI (91 aa), 31% identity in 91 aa overlap; Fasta hit to YJFY_ECOLI (91 aa), 33% identity in 87 aa overlap; Fasta hit to YBIJ_ECOLI (86 aa), 47% identity in 88 aa overlap; Orthologue of E. coli YHCN_ECOLI; Fasta hit to YHCN_ECOLI (87 aa), 78% identity in 87 aa overlap. (87 aa)
STY3543Conserved hypothetical protein; Fasta hit to YCFR_ECOLI (85 aa), 34% identity in 89 aa overlap; Fasta hit to YJFN_ECOLI (100 aa), 34% identity in 93 aa overlap; Fasta hit to YJFY_ECOLI (91 aa), 30% identity in 86 aa overlap; Fasta hit to YKGI_ECOLI (83 aa), 35% identity in 80 aa overlap; Fasta hit to YBIJ_ECOLI (86 aa), 37% identity in 90 aa overlap; Paralogue of E. coli YHCN_ECOLI; Fasta hit to YHCN_ECOLI (87 aa), 53% identity in 88 aa overlap. (88 aa)
STY3544Conserved hypothetical protein; Orthologue of E. coli YHCO_ECOLI; Fasta hit to YHCO_ECOLI (90 aa), 77% identity in 90 aa overlap. (90 aa)
STY3545Putative membrane protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. (655 aa)
STY3546Possible exported protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (310 aa)
STY3546aSimilar to Escherichia coli hypothetical protein YhcR SW:YHCR_ECOLI (P46478) (90 aa) fasta scores: E(): 5.6e-29, 98.5% id in 67 aa. (67 aa)
STY3746Putative membrane protein; Similar to Escherichia coli hypothetical 13.0 kDa protein in udha-trma intergenic region yijD SW:YIJD_ECOLI (P27308) (119 aa) fasta scores: E(): 0, 89.9% id in 119 aa. Contains possible membrane spanning hydrophobic domains. (119 aa)
STY3777Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (330 aa)
STY3782Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (79 aa)
STY3787Putative membrane protein; Orthologue of E. coli yiiR (YIIR_ECOLI); Fasta hit to YIIR_ECOLI (146 aa), 90% identity in 141 aa overlap. Contains possible membrane spanning hydrophobic domains. (142 aa)
STY3788Conserved hypothetical protein; Orthologue of E. coli yiiQ (YIIQ_ECOLI); Fasta hit to YIIQ_ECOLI (199 aa), 82% identity in 198 aa overlap. (198 aa)
STY3862Conserved hypothetical protein; Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown (By similarity); Belongs to the oligogalacturonate-specific porin KdgM (TC 1.B.35) family. OmpL subfamily. (230 aa)
STY3885Conserved hypothetical protein; Orthologue of E. coli yihD (YIHD_ECOLI); Fasta hit to YIHD_ECOLI (89 aa), 94% identity in 89 aa overlap. (89 aa)
STY3899Conserved hypothetical protein; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (498 aa)
STY3900Conserved hypothetical protein; Orthologue of E. coli YIEM_ECOLI; Fasta hit to YIEM_ECOLI (427 aa), 89% identity in 427 aa overlap. Note the predicted product of this CDS is 56 residues longer than the E. coli orthologue. (483 aa)
STY3906ATP synthase protein I; Orthologue of E. coli atpI (ATPZ_ECOLI); Fasta hit to ATPZ_ECOLI (125 aa), 91% identity in 124 aa overlap. Contains possible membrane spanning hydrophobic domains. (126 aa)
STY3968Putative lipoprotein; Orthologue of E. coli o135 (YIDQ_ECOLI); Fasta hit to YIDQ_ECOLI (135 aa), 84% identity in 109 aa overlap. Contains a possible N-terminal signal sequence. (111 aa)
STY4045Putative exported protein; Similar to Escherichia coli hypothetical 62.3 kDa protein in glts-selc intergenic region yicH SW:YICH_ECOLI (P31433) (569 aa) fasta scores: E(): 0, 79.9% id in 567 aa. (569 aa)
STY4124Insertion element IS1 protein InsA; Fasta hit to ISA2_ECOLI (91 aa), 90% identity in 91 aa overlap; Paralogue of E. coli insA_5 (ISA1_ECOLI); Fasta hit to ISA1_ECOLI (91 aa), 98% identity in 91 aa overlap. (91 aa)
insB-2Similar to Escherichia coli insertion element IS1 protein InsB insB SW:INSB_ECOLI (P03830) (167 aa) fasta scores: E(): 0, 97.0% id in 167 aa. (167 aa)
STY4135Putative exported amidase; Orthologue of E. coli BAX_ECOLI; Fasta hit to BAX_ECOLI (274 aa), 89% identity in 274 aa overlap. Contains a probable N-terminal signal sequence. (274 aa)
STY4155Conserved hypothetical protein; Orthologue of E. coli yiaF (YIAF_ECOLI); Fasta hit to YIAF_ECOLI (276 aa), 86% identity in 256 aa overlap. (236 aa)
yhjJPutative zinc-protease precursor; Similar to Escherichia coli protein YhjJ precursor yhjJ SW:YHJJ_ECOLI (P37648) (498 aa) fasta scores: E(): 0, 85.7% id in 498 aa, and to Escherichia coli probable zinc protease PqqL pqqL SW:PQQL_ECOLI (P31828) (931 aa) fasta scores: E(): 9.4e-16, 23.2% id in 504 aa; Orthologue of E. coli yhjJ (YHJJ_ECOLI); Fasta hit to YHJJ_ECOLI (498 aa), 86% identity in 498 aa overlap; Belongs to the peptidase M16 family. (495 aa)
STY4193Putative membrane protein; Orthologue of E. coli YHJG_ECOLI; Fasta hit to YHJG_ECOLI (691 aa), 92% identity in 686 aa overlap. (686 aa)
STY4194Hypothetical metabolite transport protein; Fasta hit to KGTP_ECOLI (432 aa), 32% identity in 434 aa overlap; Fasta hit to PROP_ECOLI (500 aa), 34% identity in 429 aa overlap; Fasta hit to SHIA_ECOLI (438 aa), 35% identity in 443 aa overlap; Orthologue of E. coli yhjE (YHJE_ECOLI); Fasta hit to YHJE_ECOLI (440 aa), 94% identity in 440 aa overlap. (440 aa)
STY4195Putative membrane protein; Orthologue of E. coli yhjD (YHJD_ECOLI); Fasta hit to YHJD_ECOLI (337 aa), 86% identity in 341 aa overlap. (342 aa)
STY4212Universal stress protein A; Required for resistance to DNA-damaging agents. (144 aa)
STY4213Similar to Escherichia coli universal stress protein B UspB SW:USPB_ECOLI (P37632) (111 aa) fasta scores: E(): 0, 95.5% id in 111 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (111 aa)
STY4237Putative membrane protein; Similar to Escherichia coli hypothetical 13.5 kDa protein in ftsY-nikA intergenic region YhhM SW:YHHM_ECOLI (P37615) (119 aa) fasta scores: E(): 0, 85.3% id in 116 aa. N-terminal hydrophobic region, probable membrane spanning domain. (123 aa)
yrfFPutative membrane protein; Similar to Escherichia coli hypothetical 79.5 kDa protein in mrcA-pckA intergenic region YrfF SW:YRFF_ECOLI (P45800) (711 aa) fasta scores: E(): 0, 83.9% id in 710 aa, and to Proteus mirabilis UmoB TR:O86988 (EMBL:U66822) (702 aa) fasta scores: E(): 0, 39.2% id in 701 aa. This CDS contains a signal sequence and several transmembrane regions. (710 aa)
damXDamX protein; Non-essential cell division protein. (425 aa)
yhfCPutative membrane protein; Similar to Escherichia coli hypothetical 43.2 kDa protein in ppia-nirb intergenic region yhfC SW:YHFC_ECOLI (P21229) (393 aa) fasta scores: E(): 0, 91.3% id in 393 aa. (393 aa)
STY4406Putative membrane protein; Similar to Escherichia coli hypothetical 59.5 kDa protein in metH-pepE intergenic region YjbB SW:YJBB_ECOLI (P32683) (543 aa) fasta scores: E(): 0, 92.8% id in 543 aa, and to Agrobacterium tumefaciens hypothetical 58.9 kDa protein TR:Q9WWA8 (EMBL:AF065245) (547 aa) fasta scores: E(): 0, 35.2% id in 537 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (543 aa)
STY4440Putative membrane protein; Similar to Escherichia coli hypothetical protein YjbO SW:YJBO_ECOLI (P32696) (80 aa) fasta scores: E(): 1.9e-23, 82.5% id in 80 aa. Contains predicted transmembrane helices. (80 aa)
STY4441Similar to Escherichia coli quinone oxidoreductase qor SW:QOR_ECOLI (P28304) (327 aa) fasta scores: E(): 0, 90.2% id in 327 aa, and to Pseudomonas aeruginosa quinone oxidoreductase qor SW:QOR_PSEAE (P43903) (325 aa) fasta scores: E(): 0, 60.9% id in 327 aa. (327 aa)
yjeIPutative membrane protein; Similar to Escherichia coli hypothetical protein YjeI yjeI SW:YJEI_ECOLI (P39278) (128 aa) fasta scores: E(): 0, 89.4% id in 123 aa. (123 aa)
yjePPutative membrane protein; Similar to Escherichia coli hypothetical 123.8 kDa protein in genx-psd intergenic region precursor yjeP SW:YJEP_ECOLI (P39285) (1107 aa) fasta scores: E(): 0, 89.0% id in 1108 aa.Contains possible membrane spanning hydrophobic domains. (1108 aa)
yjeTPutative membrane protein; Similar to Escherichia coli hypothetical 7.2 kDa protein in hflc-pura intergenic region yjeT SW:YJET_ECOLI (P39289) (65 aa) fasta scores: E(): 4.1e-22, 89.2% id in 65 aa Contains possible membrane spanning hydrophobic domains. (65 aa)
yjfNSimilar to Escherichia coli hypothetical protein YjfN yjfN SW:YJFN_ECOLI (P39296) (100 aa) fasta scores: E(): 1.6e-27, 79.8% id in 94 aa. (107 aa)
yjfOPutative exported protein; Similar to Escherichia coli hypothetical protein YjfO yjfO SW:YJFO_ECOLI (P39297) (142 aa) fasta scores: E(): 4.4e-31, 77.1% id in 109 aa. Contains a probable N-terminal signal sequence. (109 aa)
yjfPSimilar to Escherichia coli hypothetical 27.6 kDa protein in aidb-sgat intergenic region yjfP SW:YJFP_ECOLI (P39298) (249 aa) fasta scores: E(): 0, 71.9% id in 249 aa. (249 aa)
yjfYSimilar to Escherichia coli hypothetical 10.1 kDa protein in sgae-rpsf intergenic region precursor yjfY SW:YJFY_ECOLI (P39307) (91 aa) fasta scores: E(): 1.6e-26, 70.3% id in 91 aa. (91 aa)
ytfBSimilar to Escherichia coli hypothetical protein YtfB ytfB SW:YTFB_ECOLI (P39310) (212 aa) fasta scores: E(): 0, 85.8% id in 212 aa and to the carboxy terminal of Haemophilus influenzae opacity associated proteins OapA or HI0330 SW:OAPA_HAEIN (P44415) (431 aa) fasta scores: E(): 6.4e-05, 28.4% id in 148 aa. (211 aa)
ytfJPutative exported protein; Similar to Escherichia coli protein YtfJ precursor ytfJ SW:YTFJ_ECOLI (P39187) (184 aa) fasta scores: E(): 0, 85.2% id in 183 aa, and to Haemophilus influenzae hypothetical protein Hi0045 precursor hi0045 SW:YTFJ_HAEIN (P44478) (184 aa) fasta scores: E(): 2.2e-28, 43.3% id in 180 aa. Contains a possible N-terminal signal sequence. (185 aa)
ytfKSimilar to Escherichia coli hypothetical 8.1 kDa protein in cysq-msra intergenic region ytfK SW:YTFK_ECOLI (P39318) (68 aa) fasta scores: E(): 1.4e-25, 97.1% id in 68 aa. (90 aa)
mdoBPutative phosphoglycerol transferase; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa)
smpPutative membrane protein; Similar to Escherichia coli smp protein precursor SW:SMP_ECOLI (P18838) (214 aa) fasta scores: E(): 0, 91.1% id in 214 aa. (214 aa)
trpRProbable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). (108 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (18%) [HD]