STRINGSTRING
STY1378 STY1378 STY2145 STY2145 STY3460 STY3460 STY4441 STY4441 trpR trpR
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Your Input:
STY1378Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] (513 aa)
STY2145Tyrosine-specific transport protein; Fasta hit to TNAB_ECOLI (415 aa), 32% identity in 409 aa overlap; Fasta hit to MTR_ECOLI (414 aa), 34% identity in 399 aa overlap; Orthologue of E. coli tyrP (TYRP_ECOLI); Fasta hit to TYRP_ECOLI (403 aa), 89% identity in 403 aa overlap. (403 aa)
STY3460Probable amino acid permease; Fasta hit to TNAB_ECOLI (415 aa), 54% identity in 406 aa overlap; Fasta hit to TYRP_ECOLI (403 aa), 35% identity in 401 aa overlap; Orthologue of E. coli mtr (MTR_ECOLI); Fasta hit to MTR_ECOLI (414 aa), 95% identity in 414 aa overlap. (414 aa)
STY4441Similar to Escherichia coli quinone oxidoreductase qor SW:QOR_ECOLI (P28304) (327 aa) fasta scores: E(): 0, 90.2% id in 327 aa, and to Pseudomonas aeruginosa quinone oxidoreductase qor SW:QOR_PSEAE (P43903) (325 aa) fasta scores: E(): 0, 60.9% id in 327 aa. (327 aa)
trpRProbable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). (108 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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