node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY1378 | STY2145 | gene:17585336 | gene:17586052 | Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] | Tyrosine-specific transport protein; Fasta hit to TNAB_ECOLI (415 aa), 32% identity in 409 aa overlap; Fasta hit to MTR_ECOLI (414 aa), 34% identity in 399 aa overlap; Orthologue of E. coli tyrP (TYRP_ECOLI); Fasta hit to TYRP_ECOLI (403 aa), 89% identity in 403 aa overlap. | 0.803 |
STY1378 | trpR | gene:17585336 | gene:17588748 | Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | 0.668 |
STY2145 | STY1378 | gene:17586052 | gene:17585336 | Tyrosine-specific transport protein; Fasta hit to TNAB_ECOLI (415 aa), 32% identity in 409 aa overlap; Fasta hit to MTR_ECOLI (414 aa), 34% identity in 399 aa overlap; Orthologue of E. coli tyrP (TYRP_ECOLI); Fasta hit to TYRP_ECOLI (403 aa), 89% identity in 403 aa overlap. | Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] | 0.803 |
STY2145 | trpR | gene:17586052 | gene:17588748 | Tyrosine-specific transport protein; Fasta hit to TNAB_ECOLI (415 aa), 32% identity in 409 aa overlap; Fasta hit to MTR_ECOLI (414 aa), 34% identity in 399 aa overlap; Orthologue of E. coli tyrP (TYRP_ECOLI); Fasta hit to TYRP_ECOLI (403 aa), 89% identity in 403 aa overlap. | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | 0.517 |
STY3460 | trpR | gene:17587310 | gene:17588748 | Probable amino acid permease; Fasta hit to TNAB_ECOLI (415 aa), 54% identity in 406 aa overlap; Fasta hit to TYRP_ECOLI (403 aa), 35% identity in 401 aa overlap; Orthologue of E. coli mtr (MTR_ECOLI); Fasta hit to MTR_ECOLI (414 aa), 95% identity in 414 aa overlap. | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | 0.644 |
STY4441 | trpR | gene:17588273 | gene:17588748 | Similar to Escherichia coli quinone oxidoreductase qor SW:QOR_ECOLI (P28304) (327 aa) fasta scores: E(): 0, 90.2% id in 327 aa, and to Pseudomonas aeruginosa quinone oxidoreductase qor SW:QOR_PSEAE (P43903) (325 aa) fasta scores: E(): 0, 60.9% id in 327 aa. | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | 0.735 |
trpR | STY1378 | gene:17588748 | gene:17585336 | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] | 0.668 |
trpR | STY2145 | gene:17588748 | gene:17586052 | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | Tyrosine-specific transport protein; Fasta hit to TNAB_ECOLI (415 aa), 32% identity in 409 aa overlap; Fasta hit to MTR_ECOLI (414 aa), 34% identity in 399 aa overlap; Orthologue of E. coli tyrP (TYRP_ECOLI); Fasta hit to TYRP_ECOLI (403 aa), 89% identity in 403 aa overlap. | 0.517 |
trpR | STY3460 | gene:17588748 | gene:17587310 | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | Probable amino acid permease; Fasta hit to TNAB_ECOLI (415 aa), 54% identity in 406 aa overlap; Fasta hit to TYRP_ECOLI (403 aa), 35% identity in 401 aa overlap; Orthologue of E. coli mtr (MTR_ECOLI); Fasta hit to MTR_ECOLI (414 aa), 95% identity in 414 aa overlap. | 0.644 |
trpR | STY4441 | gene:17588748 | gene:17588273 | Probable trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | Similar to Escherichia coli quinone oxidoreductase qor SW:QOR_ECOLI (P28304) (327 aa) fasta scores: E(): 0, 90.2% id in 327 aa, and to Pseudomonas aeruginosa quinone oxidoreductase qor SW:QOR_PSEAE (P43903) (325 aa) fasta scores: E(): 0, 60.9% id in 327 aa. | 0.735 |