STRINGSTRING
slyA slyA ssrA ssrA ssrB ssrB ompR ompR envZ envZ
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
slyATranscriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (144 aa)
ssrAPutative two-component sensor kinase; Similar to Salmonella typhimurium SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 98.1% id in 823 aa, and to Escherichia coli sensor protein TorS SW:TORS_ECOLI (P39453; P75887) (904 aa) fasta scores: E(): 1.3e-26, 27.8% id in 598 aa. (920 aa)
ssrBPutative two-component response regulator; Similar to Salmonella typhimurium SsrB TR:O54305 (EMBL:Z95891) (193 aa) fasta scores: E(): 0, 100.0% id in 193 aa, and to Streptococcus pneumoniae response regulator rr03 TR:Q9S1J7 (EMBL:AJ006393) (210 aa) fasta scores: E(): 1.4e-19, 34.5% id in 206 aa; Fasta hit to UHPA_ECOLI (196 aa), 33% identity in 202 aa overlap; Fasta hit to NARL_ECOLI (216 aa), 32% identity in 198 aa overlap; Paralogue of E. coli uvrY (UVRY_ECOLI); Fasta hit to UVRY_ECOLI (218 aa), 31% identity in 206 aa overlap. (212 aa)
ompRTwo-component response regulator OmpR; Member of the two-component regulatory system EnvZ/OmpR involved in regulating expression of the outer membrane porins OmpC and OmpF as well as other genes. Unlike E.coli or S.typhimurium both porins are expressed constitutively. Involved in regulation of the biosynthesis of Vi polysaccharide, a capsular antigen thought to be involved in the virulence of S.typhi. Vi antigen is synthesized at low NaCl concentrations (under 0.4 M). Binds to the promoter of both ompC and ompF (By similarity). (239 aa)
envZTwo-component sensor kinase EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in regulating expression of the outer membrane porins OmpC and OmpF as well as other genes. Unlike E.coli or S.typhimurium both porins are expressed constitutively. Involved in regulation of the biosynthesis of Vi polysaccharide, a capsular antigen thought to be involved in the virulence of S.typhi. Vi antigen is synthesized at low NaCl concentrations (under 0.4 M). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals (By sim [...] (450 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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