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bcfA bcfA bcfB bcfB bcfD bcfD bcfE bcfE bcfF bcfF bcfG bcfG STY0033 STY0033 STY0034 STY0034 safB safB safC safC safD safD stbE stbE stbD stbD stbC stbC stbB stbB stbA stbA stcD stcD stcC stcC stcB stcB stcA stcA stdC stdC stdB stdB stdA stdA stgA stgA stgB stgB sefB sefB sefC sefC sthB sthB sthA sthA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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bcfAFimbrial subunit; Similar to Salmonella typhimurium fimbrial subunit BCFA TR:Q9X604 (EMBL:AF130422) fasta scores: E(): 0, 99.4% id in 180 aa, and to Klebsiella pneumoniae fimbrial subunit type 1 precursor FIM SW:FM12_KLEPN (P12903) fasta scores: E(): 2.7e-22, 48.4% id in 184 aa; Fasta hit to YCBQ_ECOLI (182 aa), 40% identity in 180 aa overlap; Fasta hit to FIMF_ECOLI (176 aa), 30% identity in 152 aa overlap; Fasta hit to SFMA_ECOLI (191 aa), 39% identity in 179 aa overlap; Fasta hit to FIMG_ECOLI (167 aa), 34% identity in 164 aa overlap; Paralogue of E. coli fimA (FM1A_ECOLI); Fasta hi [...] (180 aa)
bcfBFimbrial chaperone; Similar to Salmonella typhimurium fimbrial chaperone BCFB TR:Q9X605 (EMBL:AF130422) fasta scores: E(): 0, 98.7% id in 228 aa, and to Salmonella typhimurium chaperone protein fimc precursor FIMC SW:FIMC_SALTY (P37923) fasta scores: E(): 0, 49.5% id in 220 aa; Fasta hit to YCBR_ECOLI (233 aa), 45% identity in 231 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 35% identity in 225 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 46% identity in 237 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 33% identity in 225 aa overlap; Fasta hit to YCBF_ECOLI (245 aa), 33% identity in [...] (228 aa)
bcfDFimbrial subunit; Similar to Salmonella typhimurium fimbrial subunit BCFD TR:Q9X606 (EMBL:AF130422) fasta scores: E(): 0, 99.1% id in 335 aa, and to Salmonella typhimurium fimh protein precursor FIMH SW:FIMH_SALTY (P37925) fasta scores: E(): 0, 48.2% id in 332 aa; Fasta hit to YCBT_ECOLI (356 aa), 32% identity in 337 aa overlap; Paralogue of E. coli SFMH_ECOLI; Fasta hit to SFMH_ECOLI (325 aa), 45% identity in 317 aa overlap. (335 aa)
bcfEFimbrial subunit; Similar to Salmonella typhimurium fimbrial subunit BCFE TR:Q9X607 (EMBL:AF130422) fasta scores: E(): 0, 98.9% id in 181 aa, and to Salmonella typhimurium type-1 fimbrial protein, a chain precursor FIMA SW:FM1A_SALTY (P37921) fasta scores: E(): 1.1e-12, 35.1% id in 154 aa; Fasta hit to FIMF_ECOLI (176 aa), 33% identity in 151 aa overlap; Fasta hit to FM1A_ECOLI (182 aa), 31% identity in 155 aa overlap; Fasta hit to SFMA_ECOLI (191 aa), 33% identity in 154 aa overlap; Fasta hit to P77789 (176 aa), 31% identity in 163 aa overlap; Fasta hit to P75860 (187 aa), 30% identit [...] (181 aa)
bcfFFimbrial subunit; Similar to Salmonella typhimurium fimbrial subunit BCFF TR:Q9X608 (EMBL:AF130422) fasta scores: E(): 0, 98.8% id in 172 aa, and to Escherichia coli fimf protein precursor FIMF SW:FIMF_ECOLI (P08189) fasta scores: E(): 7.1e-18, 39.0% id in 177 aa; Fasta hit to FIMF_ECOLI (176 aa), 39% identity in 177 aa overlap; Fasta hit to FM1A_ECOLI (182 aa), 32% identity in 163 aa overlap; Fasta hit to SFMA_ECOLI (191 aa), 34% identity in 169 aa overlap; Fasta hit to P77789 (176 aa), 34% identity in 173 aa overlap; Fasta hit to YGIL_ECOLI (183 aa), 30% identity in 179 aa overlap; F [...] (172 aa)
bcfGFimbrial chaperone; Similar to Salmonella typhimurium fimbrial chaperone BCFG TR:Q9X609 (EMBL:AF130422) fasta scores: E(): 0, 96.9% id in 229 aa, and to Escherichia coli hypothetical fimbrial chaperone in pepn-pyrd intergenic region precursor YCBF SW:YCBF_ECOLI (P40876; P75861) fasta scores: E(): 0, 41.9% id in 234 aa; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 223 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 32% identity in 216 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 33% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 36% identity in 223 aa overlap; Fasta h [...] (234 aa)
STY0033Putative exported protein; Similar to Salmonella typhimurium hypothetical 42.7 kda protein TR:Q9RH97 (EMBL:AF053353) fasta scores: E(): 0, 94.7% id in 281 aa, and to Salmonella typhi putative outer membrane protein R0135 TR:AAF69973 (EMBL:AF250878) fasta scores: E(): 4.2e-23, 30.5% id in 282 aa, and to Coxiella burnetii outer membrane protein precursor COM1 TR:Q57333 (EMBL:Z11828) fasta scores: E(): 4.6e-13, 33.2% id in 274 aa. (281 aa)
STY0034Putative membrane protein; Similar to Escherichia coli hypothetical 11.2 kda protein in csgc-mdog intergenic region precursor YMDA SW:YMDA_ECOLI (P75917) fasta scores: E(): 0.12, 29.3% id in 92 aa. Contains probable N-terminal signal sequence. (95 aa)
safBSimilar to Escherichia coli chaperone protein AggD precursor SW:AGGD_ECOLI (P46004) (252 aa) fasta scores: E(): 0, 50.9% id in 216 aa, and to Escherichia coli chaperone protein AfaB precursor afaB SW:AFAB_ECOLI (P53516) (247 aa) fasta scores: E(): 0, 48.9% id in 227 aa; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 203 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 31% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 35% identity in 199 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 30% identity in 198 aa overlap; Paralogue of E. coli yraI (YRAI_ECOLI); Fasta hit to YRAI [...] (246 aa)
safCSimilar to Escherichia coli aggregative adherence fimbria I usher protein AafC TR:Q9X4L5 (EMBL:AF114828) (856 aa) fasta scores: E(): 0, 49.9% id in 844 aa, and to Escherichia coli outer membrane usher protein AfaC precursor afaC SW:AFAC_ECOLI (P53517) (859 aa) fasta scores: E(): 0, 49.9% id in 849 aa; Fasta hit to YCBS_ECOLI (866 aa), 35% identity in 859 aa overlap; Fasta hit to YRAJ_ECOLI (838 aa), 36% identity in 843 aa overlap; Fasta hit to SFMD_ECOLI (867 aa), 35% identity in 846 aa overlap; Paralogue of E. coli fimD (FIMD_ECOLI); Fasta hit to FIMD_ECOLI (878 aa), 36% identity in 8 [...] (836 aa)
safDPutative fimbrial structural subunit; Similar to Escherichia coli AfaD protein precursor SW:AFAD_ECOLI (Q47038; Q47039; Q47040) (147 aa) fasta scores: E(): 4e-07, 28.6% id in 154 aa, and to Salmonella enteritidis SEF14 fimbrial structural subunit sefD TR:Q53997 (EMBL:U07129) (148 aa) fasta scores: E(): 7.1e-06, 22.8% id in 136 aa. (156 aa)
stbESimilar to Klebsiella pneumoniae chaperone protein MrkB precursor mrkB SW:MRKB_KLEPN (P21646) (233 aa) fasta scores: E(): 9.3e-21, 32.4% id in 204 aa, and to Bordetella pertussis chaperone protein fimb/fhad precursor fimb or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 1.8e-18, 31.7% id in 221 aa; Fasta hit to YRAI_ECOLI (231 aa), 32% identity in 222 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 32% identity in 213 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 30% identity in 207 aa overlap; Fasta hit to YBGP_ECOLI (242 aa), 31% identity in 229 aa overlap; Paralogue of E. co [...] (252 aa)
stbDPutative fimbrial protein; Similar to Yersinia pestis protein showing similarity with pilin TR:Q9ZC29 (EMBL:AL031866) (449 aa) fasta scores: E(): 1.3e-16, 28.6% id in 420 aa. (441 aa)
stbCSimilar to Escherichia coli outer membrane usher protein FimD precursor fimD SW:FIMD_ECOLI (P30130) (878 aa) fasta scores: E(): 0, 31.7% id in 877 aa, and to Salmonella typhimurium outer membrane usher protein FimD precursor fimD SW:FIMD_SALTY (P37924) (870 aa) fasta scores: E(): 0, 32.7% id in 860 aa; Fasta hit to YCBS_ECOLI (866 aa), 31% identity in 872 aa overlap; Fasta hit to YRAJ_ECOLI (838 aa), 32% identity in 840 aa overlap; Fasta hit to HTRE_ECOLI (865 aa), 31% identity in 853 aa overlap; Fasta hit to SFMD_ECOLI (867 aa), 32% identity in 856 aa overlap; Paralogue of E. coli fim [...] (853 aa)
stbBSimilar to Escherichia coli chaperone protein EcpD precursor ecpD SW:ECPD_ECOLI (P33128) (246 aa) fasta scores: E(): 7.4e-32, 40.3% id in 248 aa, and to Bordetella pertussis chaperone protein fimb/fhad precursor fimb or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 3.2e-24, 38.5% id in 208 aa; Fasta hit to YEHC_ECOLI (239 aa), 39% identity in 258 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 34% identity in 233 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 33% identity in 236 aa overlap; Paralogue of E. coli ecpD (ECPD_ECOLI); Fasta hit to ECPD_ECOLI (246 aa), 40% identity in [...] (253 aa)
stbAProbable fimbrial protein; Similar to Yersinia pestis similar to pilin precursor f17d-a TR:Q9ZC32 (EMBL:AL031866) (176 aa) fasta scores: E(): 2.2e-24, 45.5% id in 176 aa, and to Escherichia coli F17A fimbrial subunit precursor f17A TR:Q9RH94 (EMBL:AF055308) (181 aa) fasta scores: E(): 6.7e-16, 39.9% id in 183 aa. (178 aa)
stcDPutative exported protein; Orthologue of E. coli yehA (YEHA_ECOLI); Fasta hit to YEHA_ECOLI (344 aa), 50% identity in 342 aa overlap. Contains possible N-terminal signal sequence. (335 aa)
stcCSimilar to many e.g. Escherichia coli outer membrane usher protein HtrE precursor htrE SW:HTRE_ECOLI (P33129) (865 aa) fasta scores: E(): 0, 33.0% id in 854 aa. Contains probable N-terminbal signal sequence; Fasta hit to YCBS_ECOLI (866 aa), 31% identity in 804 aa overlap; Fasta hit to FIMD_ECOLI (878 aa), 31% identity in 835 aa overlap; Fasta hit to HTRE_ECOLI (865 aa), 33% identity in 855 aa overlap; Fasta hit to SFMD_ECOLI (867 aa), 31% identity in 828 aa overlap; Orthologue of E. coli yehB (YEHB_ECOLI); Fasta hit to YEHB_ECOLI (826 aa), 75% identity in 829 aa overlap. (829 aa)
stcBSimilar to many e.g. Klebsiella pneumoniae chaperone protein MrkB precursor mrkB SW:MRKB_KLEPN (P21646) (233 aa) fasta scores: E(): 6.1e-26, 35.7% id in 235 aa and Bordetella pertussis chaperone protein precursor fimB or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 8.7e-23, 33.8% id in 231 aa; Fasta hit to YRAI_ECOLI (231 aa), 30% identity in 220 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 33% identity in 216 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 35% identity in 222 aa overlap; Orthologue of E. coli yehC (YEHC_ECOLI); Fasta hit to YEHC_ECOLI (239 aa), 64% identity [...] (227 aa)
stcAPutative fimbrial subunit protein; Shows very weak similarity to e.g. Klebsiella pneumoniae fimbrial subunit type 1 precursor fim SW:FM12_KLEPN (P12903) (182 aa) fasta scores: E(): 0.11, 26.5% id in 189 aa. Contains probable N-terminal signal sequence; Orthologue of E. coli yehD (YEHD_ECOLI); Fasta hit to YEHD_ECOLI (180 aa), 32% identity in 182 aa overlap. (176 aa)
stdCWeakly similar to Escherichia coli chaperone protein PapD involved in pili assembly SW:PAPD_ECOLI (P15319) (239 aa) fasta scores: E(): 5.9e-33, 37.8% id in 238 aa; Paralogue of E. coli YBGP_ECOLI; Fasta hit to YBGP_ECOLI (242 aa), 40% identity in 222 aa overlap. (247 aa)
stdBSimilar to Escherichia coli hypothetical outer membrane usher protein YqiG SW:YQIG_ECOLI (P76655) (821 aa) fasta scores: E(): 0, 42.2% id in 812 aa. (829 aa)
stdAProbable fimbrial protein; Similar to Escherichia coli hypothetical fimbrial-like protein precursor YbgD SW:YBGD_ECOLI (P37909; P75751) (188 aa) fasta scores: E(): 4.9e-11, 31.5% id in 200 aa; Fasta hit to FIMF_ECOLI (176 aa), 32% identity in 160 aa overlap; Fasta hit to YFCP_ECOLI (179 aa), 31% identity in 159 aa overlap. (193 aa)
stgAProbable fimbrial subunit protein; Similar to several including: Klebsiella pneumoniae Fimbrial subunit type 1 precursor Fim SW:FM12_KLEPN (P12903) (182 aa) fasta scores: E(): 8e-10, 38.2% id in 191 aa and Serratia marcescens type-1 fimbrial protein subunit precursor fimA SW:FM1A_SERMA (P22595) (180 aa) fasta scores: E(): 5.3e-09, 39.2% id in 194 aa; Fasta hit to SFMF_ECOLI (171 aa), 32% identity in 173 aa overlap; Fasta hit to FM1A_ECOLI (182 aa), 37% identity in 191 aa overlap; Fasta hit to FIMF_ECOLI (176 aa), 31% identity in 177 aa overlap; Paralogue of E. coli SFMA_ECOLI; Fasta hi [...] (191 aa)
stgBSimilar to Escherichia coli chaperone protein precursor FocC SW:FOCC_ECOLI (P46008) (227 aa) fasta scores: E(): 1.1e-24, 34.9% id in 215 aa; Fasta hit to YRAI_ECOLI (231 aa), 38% identity in 219 aa overlap; Fasta hit to YBGP_ECOLI (242 aa), 34% identity in 224 aa overlap; Fasta hit to YEHC_ECOLI (239 aa), 32% identity in 226 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 34% identity in 231 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 35% identity in 226 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 36% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 34% identity in 215 a [...] (232 aa)
sefBSimilar to Salmonella enteritidis chaperone protein SefB precursor SW:SEFB_SALEN (P33387) (246 aa) fasta scores: E(): 0, 99.2% id in 246 aa, and to Yersinia pestis, and Yersinia pseudotuberculosis chaperone protein PsaB precursor SW:PSAB_YERPE (P31523) (273 aa) fasta scores: E(): 4e-25, 33.5% id in 257 aa, and to Escherichia coli chaperone protein AggD precursor SW:AGGD_ECOLI (P46004) (252 aa) fasta scores: E(): 2.1e-23, 33.5% id in 209 aa. CDS DNA has a low GC content, 28.81%. (250 aa)
sefCSimilar to Salmonella enteritidis outer membrane usher protein SefC precursor SW:SEFC_SALEN (P33388) (814 aa) fasta scores: E(): 0, 96.7% id in 838 aa, and to Salmonella typhimurium outer membrane usher protein FimD precursor fimD SW:FIMD_SALTY (P37924) (870 aa) fasta scores: E(): 0, 31.0% id in 836 aa. Identity with SefC is distrupted with Glycine-Valine repeat between codons 301 and 330. TTGGTG repeated 14 times. Possible effect on function. CDS DNA has a low GC content,35.71%. (838 aa)
sthBSimilar to Escherichia coli chaperone protein FimC SW:FIMC_ECOLI (P31697; P71220) (241 aa) fasta scores: E(): 6.3e-23, 32.6% id in 218 aa, and to Proteus mirabilis type 1 fimbrial chaperone AtfB TR:P72210 (EMBL:Z78535) (225 aa) fasta scores: E(): 7.1e-24, 33.0% id in 221 aa, and to Salmonella typhi FinC gene finC TR:Q56085 (EMBL:X74602) (237 aa) fasta scores: E(): 5.3e-23, 33.0% id in 215 aa. (227 aa)
sthAPutative fimbrial protein; Similar to Escherichia coli major fimbrial subunit protein precursor f17d-A TR:Q47196 (EMBL:L77091) (181 aa) fasta scores: E(): 2.3e-10, 33.0% id in 188 aa, and to Escherichia coli minor fimbrial subunit, precursor polypeptide fimF TR:O87737 (EMBL:AJ225176) (176 aa) fasta scores: E(): 5.5e-10, 31.0% id in 184 aa. (181 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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