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ttrR ttrR ttrB ttrB ttrC ttrC ttrA ttrA phsC phsC phsB phsB phsA phsA asrA asrA asrB asrB asrC asrC glpE glpE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ttrRPutative two-component response regulator; Similar to Salmonella typhimurium TtrR TR:Q9Z4T0 (EMBL:AJ224978) (206 aa) fasta scores: E(): 0, 100.0% id in 206 aa, and to Rhodobacter capsulatus c4-dicarboxylate transport transcriptional regulatory protein DctR SW:DCTR_RHOCA (P37740) (197 aa) fasta scores: E(): 2.1e-22, 39.1% id in 192 aa; Fasta hit to NARL_ECOLI (216 aa), 30% identity in 200 aa overlap; Paralogue of E. coli uhpA (UHPA_ECOLI); Fasta hit to UHPA_ECOLI (196 aa), 34% identity in 196 aa overlap. (206 aa)
ttrBSimilar to Salmonella typhimurium tetrathionate reductase subunit B TtrB TR:Q9Z4S8 (EMBL:AJ224978) (250 aa) fasta scores: E(): 0, 100.0% id in 250 aa and to Salmonella typhimurium thiosulfate reductase electron transport protein PhsB SW:PHSB_SALTY (P37601) (192 aa) fasta scores: E(): 1.1e-25, 46.4% id in 151 aa; Fasta hit to P77375 (239 aa), 33% identity in 228 aa overlap; Paralogue of E. coli nrfC (NRFC_ECOLI); Fasta hit to NRFC_ECOLI (223 aa), 41% identity in 222 aa overlap. (250 aa)
ttrCSimilar to Salmonella typhimurium tetrathionate reductase subunit C TtrC TR:Q9Z4S7 (EMBL:AJ224978) (340 aa) fasta scores: E(): 0, 98.2% id in 340 aa. (340 aa)
ttrASimilar to Salmonella typhimurium tetrathionate reductase subunit A TtrA TR:Q9Z4S6 (EMBL:AJ224978) (1020 aa) fasta scores: E(): 0, 99.7% id in 1020 aa and to Archaeoglobus fulgidus molybdopterin oxidoreductase, molybdopterin binding subunit, putative af0159 TR:O30078 (EMBL:AE001095) (1134 aa) fasta scores: E(): 6.4e-33, 31.1% id in 1000 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1020 aa)
phsCSimilar to Salmonella typhimurium thiosulfate reductase cytochrome b subunit phsC SW:PHSC_SALTY (P37602; P37603; Q56120) (254 aa) fasta scores: E(): 0, 99.6% id in 254 aa; Orthologue of E. coli PHSC_ECOLI; Fasta hit to PHSC_ECOLI (261 aa), 57% identity in 242 aa overlap. Contains hydrophobic, probable membrane-spanning regions. (254 aa)
phsBThiosulfate reductase electron transport protein PhsB; Component of the PhsABC thiosulfate reductase that catalyzes the reduction of thiosulfate to sulfite and hydrogen sulfide, with menaquinol as the sole electron donor. Proton motive force (PMF) is required to drive transmembrane electron transfer within the reductase. The PhsB subunit transfers electrons between PhsC and PhsA. (192 aa)
phsASimilar to Salmonella typhimurium thiosulfate reductase precursor phsA SW:PHSA_SALTY (P37600) (758 aa) fasta scores: E(): 0, 99.6% id in 758 aa. Contains a probable N-terminal signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (758 aa)
asrASimilar to Salmonella typhimurium anaerobic sulfite reductase subunit A asrA SW:ASRA_SALTY (P26474) (347 aa) fasta scores: E(): 0, 99.1% id in 347 aa. (347 aa)
asrBSimilar to Salmonella typhimurium anaerobic sulfite reductase subunit B SW:ASRB_SALTY (P26475) (272 aa) fasta scores: E(): 0, 99.3% id in 272 aa. (272 aa)
asrCAnaerobic sulfite reductase subunit C; This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine (By similarity). (337 aa)
glpEConserved hypothetical protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (108 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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