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phnV phnV phnU phnU phnT phnT phnS phnS phnR phnR phnW phnW phnX phnX STY0910 STY0910 STY0911 STY0911 STY0912 STY0912 STY0913 STY0913 STY0914 STY0914 ybjF ybjF STY0916 STY0916 STY0919 STY0919 STY1262 STY1262 STY1263 STY1263 STY1265 STY1265 STY1266 STY1266 STY4230 STY4230
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phnVProbable membrane component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). Belongs to the binding-protein-dependent transport system permease family. (263 aa)
phnUProbable membrane component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). Belongs to the binding-protein-dependent transport system permease family. (289 aa)
phnTProbable ATP-binding component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system (By similarity). (369 aa)
phnSProbable periplasmic binding component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import; Belongs to the bacterial solute-binding protein 1 family. (337 aa)
phnRProbable regulator of 2-aminoethylphosphonate uptake and metabolism operon; Previously sequenced as Salmonella typhimurium phnr TR:P96061 (EMBL:U69493) (239 aa) fasta scores: E(): 0, 100.0% id in 239 aa, and to Escherichia coli hypothetical transcriptional regulator in glnA-rbn intergenic region yihL SW:YIHL_ECOLI (P32133) (236 aa) fasta scores: E(): 4.7e-23, 33.0% id in 224 aa; Paralogue of E. coli YIHL_ECOLI; Fasta hit to YIHL_ECOLI (236 aa), 33% identity in 225 aa overlap. (239 aa)
phnW2-aminoethylphosphonate:pyruvate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (367 aa)
phnXPhosphonoacetaldehyde phosphonohydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. (269 aa)
STY0910Putrescine-binding periplasmic protein precursor; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (370 aa)
STY0911Putrescine transport ATP-binding protein PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
STY0912Putrescine transport system permease protein PotH; Fasta hit to POTB_ECOLI (275 aa), 42% identity in 268 aa overlap; Orthologue of E. coli potH (POTH_ECOLI); Fasta hit to POTH_ECOLI (317 aa), 92% identity in 317 aa overlap. (317 aa)
STY0913Putrescine transport system permease protein PotI; Fasta hit to POTC_ECOLI (264 aa), 41% identity in 248 aa overlap; Fasta hit to YDCV_ECOLI (264 aa), 33% identity in 260 aa overlap; Orthologue of E. coli potI (POTI_ECOLI); Fasta hit to POTI_ECOLI (281 aa), 94% identity in 281 aa overlap. (281 aa)
STY0914Putative membrane protein; Orthologue of E. coli YBJO_ECOLI; Fasta hit to YBJO_ECOLI (162 aa), 80% identity in 157 aa overlap. (157 aa)
ybjFHypothetical RNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily. (375 aa)
STY0916Putative membrane protein; No database matches. (69 aa)
STY0919Probable sulfatase; Similar to Prevotella spRS2. mucin-desulfating sulfatase MdsA precursor mdsA TR:AAF72520 (EMBL:AF248951) (517 aa) fasta scores: E(): 4.4e-08, 25.0% id in 480 aa, and to Escherichia coli hypothetical 57.3 kDa protein in emrd-glvg intergenic region. putative sulfatase yidj SW:YIDJ_ECOLI (P31447) (497 aa) fasta scores: E(): 1.1e-07, 24.3% id in 379 aa, and to Rhizobium meliloti choline-sulfatase betC SW:BETC_RHIME (O69787) (512 aa) fasta scores: E(): 3.1e-07, 24.4% id in 443 aa. (495 aa)
STY1262Spermidine/putrescine-binding periplasmic protein precursor; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein (By similarity); Belongs to the bacterial solute-binding protein PotD/PotF family. (348 aa)
STY1263Spermidine/putrescine transport system permease protein PotC; Fasta hit to POTI_ECOLI (281 aa), 41% identity in 255 aa overlap; Orthologue of E. coli potC (POTC_ECOLI); Fasta hit to POTC_ECOLI (264 aa), 97% identity in 258 aa overlap. (259 aa)
STY1265Spermidine/putrescine transport system permease protein PotB; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (287 aa)
STY1266Spermidine/putrescine transport ATP-binding protein PotA (ABC superfamily); Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
STY4230Putative membrane protein; Similar to Escherichia coli hypothetical 43.8 kDa protein in ftsY-nikA intergenic region YhhS SW:YHHS_ECOLI (P37621) (419 aa) fasta scores: E(): 0, 90.6% id in 405 aa, and to Escherichia coli from bases 2434445 to 2447012 YhhS TR:P77549 (EMBL:AE000321) (392 aa) fasta scores: E(): 0, 42.2% id in 372 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (405 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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