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| | STY0103 | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (282 aa) |
| | STY0104 | CorD protein; Similar to Salmonella typhimurium ApaG protein SW:APAG_SALTY (Q56017) fasta scores: E(): 0, 97.6% id in 125 aa, and to Escherichia coli ApaG protein APAG SW:APAG_ECOLI (P05636) fasta scores: E(): 0, 92.8% id in 125 aa, and to C-terminus of Homo sapiens f-box protein fbx3 TR:Q9UK99 (EMBL:AF176702) fasta scores: E(): 2.1e-09, 35.8% id in 123 aa. (125 aa) |
| | STY0105 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (273 aa) |
| | STY0106 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa) |
| | STY0107 | Survival protein SurA precursor; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (428 aa) |
| | STY0108 | Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Belongs to the LptD family. (784 aa) |
| | STY0139 | Conserved hypothetical protein; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster. (152 aa) |
| | STY0140 | Conserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa) |
| | STY0141 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (121 aa) |
| | STY0142 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (588 aa) |
| | STY0143 | UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopim ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa) |
| | STY0144 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diami nopimelate--D-alan alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (452 aa) |
| | STY0145 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | STY0146 | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (438 aa) |
| | STY0147 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (414 aa) |
| | STY0148 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa) |
| | STY0149 | UDP-N-acetylmuramate:alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (491 aa) |
| | STY0150 | D-alanine:D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa) |
| | STY0151 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (276 aa) |
| | STY0152 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (420 aa) |
| | STY0153 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (383 aa) |
| | STY0154 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa) |
| | STY0168 | Similar to Escherichia coli ampd protein AMPD SW:AMPD_ECOLI (P13016) fasta scores: E(): 0, 91.1% id in 179 aa, and to Enterobacter cloacae anhydro-N-acetylmuramyl-tripeptide amidase AMPD TR:Q46957 (EMBL:U40785) fasta scores: E(): 0, 83.9% id in 186 aa; Orthologue of E. coli ampD (AMPD_ECOLI); Fasta hit to AMPD_ECOLI (183 aa), 91% identity in 179 aa overlap. (187 aa) |
| | STY0169 | AmpE protein; Orthologue of E. coli ampE (AMPE_ECOLI); Fasta hit to AMPE_ECOLI (284 aa), 85% identity in 284 aa overlap. (284 aa) |
| | STY0173 | Aromatic amino acid transport protein AroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (456 aa) |
| | STY0215 | Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (840 aa) |
| | STY0231 | Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. (475 aa) |
| | yaeT | Outer membrane protein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (803 aa) |
| | ompH | Outer membrane protein OmpH precursor; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. (161 aa) |
| | lpxD | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (341 aa) |
| | STY0250 | (3R)-hydroxymyristol acyl carrier protein dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity). (151 aa) |
| | STY0251 | acyl-[acyl-carrier-protein]:UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa) |
| | STY0252 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa) |
| | mltD | Similar to Escherichia coli membrane-bound lytic murein transglycosylase d precursor mltd or dniR SW:MLTD_ECOLI (P23931; P32982; P77350) (452 aa) fasta scores: E(): 0, 91.4% id in 455 aa, and to Neisseria meningitidis |+++ unknown: ox in cab84739 +++| putative membrane bound murein transglycosylase TR:CAB84739 (EMBL:AL162756) (658 aa) fasta scores: E(): 4.4e-32, 35.2% id in 341 aa, and to Bacteriophage phi-LC3 LysB lysB TR:Q37969 (EMBL:U04309) (429 aa) fasta scores: E(): 3.9e-06, 30.4% id in 161 aa; Orthologue of E. coli dniR (MLTD_ECOLI); Fasta hit to MLTD_ECOLI (452 aa), 91% identity [...] (455 aa) |
| | STY0338 | Conserved hypothetical protein; Similar to Escherichia coli ShF TR:Q9X692 (EMBL:AF134403) (280 aa) fasta scores: E(): 0, 63.7% id in 267 aa, and to Shigella flexneri Shf1 TR:P72436 (EMBL:U61977) (132 aa) fasta scores: E(): 4.3e-29, 61.0% id in 118 aa. (273 aa) |
| | STY0357 | Putative exported protein; Orthologue of E. coli yafK (YAFK_ECOLI); Fasta hit to YAFK_ECOLI (246 aa), 91% identity in 246 aa overlap. (246 aa) |
| | STY0412 | D-alanine:D-alanine ligase A; Cell wall formation. (364 aa) |
| | STY0486 | AmpG protein; Orthologue of E. coli ampG (AMPG_ECOLI); Fasta hit to AMPG_ECOLI (491 aa), 91% identity in 490 aa overlap. (491 aa) |
| | STY0583 | Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa) |
| | STY0584 | Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa) |
| | STY0587 | Conserved hypothetical protein; Orthologue of E. coli ybcJ (YBCJ_ECOLI); Fasta hit to YBCJ_ECOLI (70 aa), 93% identity in 70 aa overlap. (70 aa) |
| | tatE | Sec-independent protein translocase protein TatE; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. (67 aa) |
| | STY0688 | D-alanine carboxypeptidase; Fasta hit to DACC_ECOLI (400 aa), 60% identity in 401 aa overlap; Fasta hit to DACD_ECOLI (388 aa), 48% identity in 390 aa overlap; Orthologue of E. coli dacA (DACA_ECOLI); Fasta hit to DACA_ECOLI (403 aa), 95% identity in 403 aa overlap; Belongs to the peptidase S11 family. (403 aa) |
| | STY0690 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa) |
| | pbpA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (633 aa) |
| | STY0698 | Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (196 aa) |
| | STY0704 | Conserved hypothetical protein; Orthologue of E. coli ybeL (YBEL_ECOLI); Fasta hit to YBEL_ECOLI (160 aa), 91% identity in 160 aa overlap. (157 aa) |
| | STY0735 | seqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. (180 aa) |
| | STY0790 | Conserved hypothetical protein; Orthologue of E. coli ybgC (YBGC_ECOLI); Fasta hit to YBGC_ECOLI (134 aa), 92% identity in 134 aa overlap. (134 aa) |
| | STY0791 | TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa) |
| | STY0792 | tolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa) |
| | STY0793 | tolA protein; Orthologue of E. coli tolA (TOLA_ECOLI); Fasta hit to TOLA_ECOLI (421 aa), 68% identity in 421 aa overlap. (376 aa) |
| | STY0794 | tolB protein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa) |
| | STY0795 | Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (174 aa) |
| | STY0796 | Putative exported protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (262 aa) |
| | STY0835 | Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (302 aa) |
| | ybiS | Putative exported protein; Similar to Escherichia coli protein YbiS precursor ybiS SW:YBIS_ECOLI (P75789) (306 aa) fasta scores: E(): 0, 92.5% id in 306 aa, and to Escherichia coli protein ErfK/srfk precursor erfK SW:ERFK_ECOLI (P39176) (310 aa) fasta scores: E(): 0, 65.8% id in 295 aa, and to Escherichia coli hypothetical 34.6 kDa protein in ndh-mfd intergenic region precursor ycfS SW:YCFS_ECOLI (P75954) (320 aa) fasta scores: E(): 0, 51.7% id in 302 aa. Contains probable N-terminal signal sequence; Fasta hit to YNHG_ECOLI (334 aa), 47% identity in 305 aa overlap; Fasta hit to YCFS_EC [...] (306 aa) |
| | STY0896 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6 precursor); Fasta hit to DACD_ECOLI (388 aa), 47% identity in 384 aa overlap; Fasta hit to DACA_ECOLI (403 aa), 61% identity in 397 aa overlap; Orthologue of E. coli dacC (DACC_ECOLI); Fasta hit to DACC_ECOLI (400 aa), 92% identity in 400 aa overlap; Belongs to the peptidase S11 family. (400 aa) |
| | STY0958 | Cell division protein FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA [...] (1343 aa) |
| | STY0959 | Outer membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa) |
| | STY0979 | Putative lipoprotein; Fasta hit to YGGG_ECOLI (252 aa), 56% identity in 251 aa overlap; Orthologue of E. coli YCAL_ECOLI; Fasta hit to YCAL_ECOLI (254 aa), 70% identity in 254 aa overlap. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (253 aa) |
| | STY0985 | Probable transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (325 aa) |
| | STY0990 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (248 aa) |
| | STY0997 | Putative exported protein; Orthologue of E. coli ycbB (YCBB_ECOLI); Fasta hit to YCBB_ECOLI (615 aa), 85% identity in 618 aa overlap. (615 aa) |
| | STY0998 | Putative exported protein; Orthologue of E. coli YCBK_ECOLI; Fasta hit to YCBK_ECOLI (182 aa), 95% identity in 182 aa overlap. Contains a possible N-terminal signal sequence. (182 aa) |
| | STY1184 | Conserved hypothetical protein; Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation; Belongs to the YmdB family. (186 aa) |
| | STY1192 | Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) (heat shock protein); Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) |
| | STY1228 | Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (194 aa) |
| | STY1249 | Putative glycosyl hydrolase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (341 aa) |
| | STY1257 | ABC transporter integral membrane subunit; Orthologue of E. coli YCFU_ECOLI; Fasta hit to YCFU_ECOLI (399 aa), 94% identity in 399 aa overlap. (436 aa) |
| | STY1258 | ABC transporter ATP-binding subunit; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa) |
| | STY1259 | ABC transporter integral membrane subunit; Orthologue of E. coli YCFW_ECOLI; Fasta hit to YCFW_ECOLI (414 aa), 93% identity in 414 aa overlap. (414 aa) |
| | STY1482 | Hypothetical protein; No significant database matches. (210 aa) |
| | STY1483 | Similar to Salmonella typhimurium N-hydroxyarylamine O-acetyltransferase SW:NHOA_SALTY () (281 aa) fasta scores: E(): 0, 98.6% id in 281 aa, and to Mycobacterium smegmatis arylamine N-acetyltransferase naT SW:NAT_MYCSM (O86309) (275 aa) fasta scores: E(): 3e-26, 35.1% id in 271 aa; Orthologue of E. coli NHOA_ECOLI; Fasta hit to NHOA_ECOLI (281 aa), 75% identity in 281 aa overlap. (281 aa) |
| | STY1656 | Conserved hypothetical protein; Fasta hit to YIHF_ECOLI (490 aa), 33% identity in 484 aa overlap; Orthologue of E. coli YDGA_ECOLI; Fasta hit to YDGA_ECOLI (502 aa), 80% identity in 502 aa overlap. (502 aa) |
| | STY1690 | Putative secreted protein; Fasta hit to YAFL_ECOLI (249 aa), 35% identity in 267 aa overlap; Orthologue of E. coli YDHO_ECOLI; Fasta hit to YDHO_ECOLI (271 aa), 73% identity in 275 aa overlap. (284 aa) |
| | STY1897 | 2-dehydro-3-deoxyphosphooctonate aldolase; Orthologue of E. coli kdsA (KDSA_ECOLI); Fasta hit to KDSA_ECOLI (284 aa), 94% identity in 282 aa overlap; Belongs to the KdsA family. (284 aa) |
| | STY1904 | Outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (207 aa) |
| | STY1930 | Alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. (356 aa) |
| | STY1931 | D-amino acid dehydrogenase; Oxidative deamination of D-amino acids. (432 aa) |
| | STY1934 | Fatty acid-fatty acyl responsive DNA-binding protein; Multifunctional regulator of fatty acid metabolism. Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE. Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the glyoxylate shunt enzymes. Binding of FadR is specifically inhibited by long chain fatty acyl-CoA compounds (By similarity). (239 aa) |
| | STY1941 | Similar to Escherichia coli hypothetical 17.9 kDa protein in minc-shea intergenic region ycgN SW:YCGN_ECOLI (P76005) (153 aa) fasta scores: E(): 0, 91.5% id in 153 aa, and to Rhodobacter capsulatus hypothetical 17.4 kDa protein TR:O68068 (EMBL:AF010496) (149 aa) fasta scores: E(): 4.5e-28, 51.1% id in 139 aa; Belongs to the UPF0260 family. (153 aa) |
| | ftsI2 | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa) |
| | STY1976 | Tail-specific protease precursor; Orthologue of E. coli prc (PRC_ECOLI); Fasta hit to PRC_ECOLI (682 aa), 93% identity in 682 aa overlap; Belongs to the peptidase S41A family. (682 aa) |
| | proP | ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. (228 aa) |
| | STY2098 | Conserved hypothetical protein; Unknown function. Similar to many bacterial hypothetical proteins; Orthologue of E. coli yebA (YEBA_ECOLI); Fasta hit to YEBA_ECOLI (419 aa), 92% identity in 419 aa overlap. (439 aa) |
| | STY2198 | Putative membrane protein; Orthologue of E. coli yedA (YEDA_ECOLI); Fasta hit to YEDA_ECOLI (306 aa), 88% identity in 306 aa overlap. Contains a possible N-terminal signal sequence and possible membrane spanning hydrophobic domains. (306 aa) |
| | STY2218 | Putative exported protein; Similar to Salmonella typhimurium protein erfK/srfK precursor SW:ERFK_SALTY (P40680) (309 aa) fasta scores: E(): 0, 99.0% id in 309 aa. Contains probable N-terminal signal sequence; Fasta hit to YNHG_ECOLI (334 aa), 47% identity in 288 aa overlap; Fasta hit to YCFS_ECOLI (320 aa), 48% identity in 307 aa overlap; Fasta hit to YBIS_ECOLI (306 aa), 66% identity in 283 aa overlap; Orthologue of E. coli erfK (ERFK_ECOLI); Fasta hit to ERFK_ECOLI (310 aa), 79% identity in 305 aa overlap. (309 aa) |
| | STY2264 | Conserved hypothetical protein; Orthologue of E. coli YEEX_ECOLI; Fasta hit to YEEX_ECOLI (109 aa), 94% identity in 109 aa overlap; Belongs to the UPF0265 family. (111 aa) |
| | yejK | Nucleoid-asociated protein; Similar to Escherichia coli 37 kDa nucleoid-associated protein yejK SW:NA37_ECOLI (P33920) (334 aa) fasta scores: E(): 0, 96.4% id in 333 aa and Haemophilus influenzae 37 kDa nucleoid-associated protein homolog HI0839 SW:NA37_HAEIN (P44896) (341 aa) fasta scores: E(): 0, 53.2% id in 333 aa. (335 aa) |
| | STY2465 | Conserved hypothetical protein; Orthologue of E. coli yejL (YEJL_ECOLI); Fasta hit to YEJL_ECOLI (75 aa), 91% identity in 75 aa overlap; Belongs to the UPF0352 family. (75 aa) |
| | STY2466 | Putative sulphatase; Orthologue of E. coli yejM (YEJM_ECOLI); Fasta hit to YEJM_ECOLI (586 aa), 87% identity in 586 aa overlap. Contains hydrophobic, probable membrane-spanning regions in the N-terminal half. (586 aa) |
| | STY2566 | Similar to Vibrio cholerae hypothetical protein VC1099 TR:Q9KT06 (EMBL:AE004191) (152 aa) fasta scores: E(): 1.1e-24, 46.6% id in 146 aa and Haemophilus influenzae hypothetical protein HIL205 SW:YC05_HAEIN (P44127) (147 aa) fasta scores: E(): 7.5e-22, 44.1% id in 145 aa; Orthologue of E. coli P77496; Fasta hit to P77496 (151 aa), 95% identity in 151 aa overlap. (151 aa) |
| | STY2618 | Conserved hypothetical protein; Orthologue of E. coli YFCN_ECOLI; Fasta hit to YFCN_ECOLI (183 aa), 94% identity in 183 aa overlap; Belongs to the UPF0115 family. (183 aa) |
| | STY2619 | Phosphohistidine phosphatase; Orthologue of E. coli SIXA_ECOLI; Fasta hit to SIXA_ECOLI (161 aa), 89% identity in 161 aa overlap. (161 aa) |
| | STY2624 | VacJ lipoprotein precursor; Orthologue of E. coli vacJ (VACJ_ECOLI); Fasta hit to VACJ_ECOLI (251 aa), 94% identity in 251 aa overlap. (251 aa) |
| | STY2639 | Putative acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (306 aa) |
| | STY2664 | Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (328 aa) |
| | STY2687 | Similar to Salmonella typhimurium probable N-acetylmuramoyl-L-alanine amidase amiA precursor SW:AMIA_SALTY (P33772) (289 aa) fasta scores: E(): 0, 99.7% id in 289 aa; Orthologue of E. coli amiA (AMIA_ECOLI); Fasta hit to AMIA_ECOLI (289 aa), 93% identity in 289 aa overlap. (289 aa) |
| | STY2716 | Putative exported protein; Possible orthologue of E. coli YFEW_ECOLI; Fasta hit to YFEW_ECOLI (434 aa), 73% identity in 432 aa overlap. Contains probable N-terminal signal sequence; Belongs to the peptidase S12 family. YfeW subfamily. (432 aa) |
| | STY2726 | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (344 aa) |
| | STY2728 | Glycine cleavage system transcriptional repressor; Orthologue of E. coli gcvR (GCVR_ECOLI); Fasta hit to GCVR_ECOLI (189 aa), 91% identity in 189 aa overlap. (212 aa) |
| | STY2734 | Putative membrane protein; Orthologue of E. coli PERM_ECOLI; Fasta hit to PERM_ECOLI (353 aa), 95% identity in 350 aa overlap. Contains hydrophobic, probable membrane-spanning regions. (355 aa) |
| | STY2735 | Putative exported protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (487 aa) |
| | STY2765 | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (392 aa) |
| | STY2769 | Putative DNA-binding protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. (324 aa) |
| | STY2813 | Putative exported protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (475 aa) |
| | STY2852 | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (245 aa) |
| | STY2871 | Small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (112 aa) |
| | STY2952 | Membrane-bound lytic transglycosylase B precursor; Orthologue of E. coli mltB (MLTB_ECOLI); Fasta hit to MLTB_ECOLI (361 aa), 92% identity in 361 aa overlap. (359 aa) |
| | STY3106 | Syd protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. (181 aa) |
| | STY3120 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (366 aa) |
| | STY3121 | Conserved hypothetical protein; Orthologue of E. coli ygdD (YGDD_ECOLI); Fasta hit to YGDD_ECOLI (131 aa), 90% identity in 131 aa overlap. (131 aa) |
| | STY3122 | Regulatory protein for glycine cleavage pathway; Fasta hit to PERR_ECOLI (297 aa), 35% identity in 286 aa overlap; Fasta hit to DSDC_ECOLI (311 aa), 31% identity in 294 aa overlap; Fasta hit to YAFC_ECOLI (304 aa), 31% identity in 281 aa overlap; Fasta hit to YEAT_ECOLI (307 aa), 33% identity in 258 aa overlap; Orthologue of E. coli gcvA (GCVA_ECOLI); Fasta hit to GCVA_ECOLI (305 aa), 98% identity in 305 aa overlap; Belongs to the LysR transcriptional regulatory family. (305 aa) |
| | STY3128 | Membrane-bound lytic murein transglycosylase A precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (365 aa) |
| | STY3129 | Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiC precursor SW:AMIC_ECOLI () (417 aa) fasta scores: E(): 0, 94.2% id in 416 aa. Contains a possible N-terminal signal sequence; Fasta hit to AMIB_ECOLI (445 aa), 31% identity in 414 aa overlap; Orthologue of E. coli AMIC_ECOLI; Fasta hit to AMIC_ECOLI (417 aa), 94% identity in 416 aa overlap. (417 aa) |
| | STY3148 | DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. (231 aa) |
| | STY3194 | Possible lipoprotein; Similar to Escherichia coli TR:Q46798 (EMBL:U28375) (259 aa) fasta scores: E(): 0, 85.7% id in 252 aa, and to Salmonella dublin NlpD protein TR:CAA06881 (EMBL:AJ006131) (377 aa) fasta scores: E(): 8.2e-28, 43.7% id in 270 aa. Contains a possible N-terminal signal sequence; Orthologue of E. coli Q46798; Fasta hit to Q46798 (259 aa), 86% identity in 252 aa overlap. (250 aa) |
| | STY3200 | Site-specific integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically e [...] (298 aa) |
| | STY3201 | Flavodoxin II; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (173 aa) |
| | STY3223 | Putative membrane protein; Orthologue of E. coli yggB (YGGB_ECOLI); Fasta hit to YGGB_ECOLI (286 aa), 92% identity in 285 aa overlap. Contains possible membrane spanning hydrophobic domains. (286 aa) |
| | mltC | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (361 aa) |
| | STY3349 | SufI protein; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress. (470 aa) |
| | STY3380 | Adenyl-transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) [...] (947 aa) |
| | STY3381 | Conserved hypothetical protein; Orthologue of E. coli ygiF (YGIF_ECOLI); Fasta hit to YGIF_ECOLI (433 aa), 85% identity in 433 aa overlap. (433 aa) |
| | STY3405 | Probable membrane transport protein; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (414 aa) |
| | STY3462 | Conserved hypothetical protein; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). (294 aa) |
| | STY3476 | Conserved hypothetical protein; Orthologue of E. coli yhbY (YHBY_ECOLI); Fasta hit to YHBY_ECOLI (97 aa), 96% identity in 97 aa overlap. Note codon 14 offers an alternative translational start site. (110 aa) |
| | STY3479 | Penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase); Orthologue of E. coli dacB (PBP4_ECOLI); Fasta hit to PBP4_ECOLI (477 aa), 94% identity in 477 aa overlap. (477 aa) |
| | STY3486 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | STY3487 | Conserved hypothetical protein; Similar to Escherichia coli protein YrbA SW:YRBA_ECOLI (P43781; P76672) (84 aa) fasta scores: E(): 0, 97.6% id in 84 aa. Weakly similar to several BolA-like proteins involved in the general stress response e.g.and to Pseudomonas fluorescens BolA protein TR:Q9XAV4 (EMBL:AJ243174) (99 aa) fasta scores: E(): 1.3e-07, 37.5% id in 72 aa. Note codon 14 offers an alternative translational start site; Belongs to the BolA/IbaG family. (97 aa) |
| | STY3488 | Possible anti-sigma factor antagonist; Similar to the C-terminus of Escherichia coli hypothetical 14.4 kDa protein in YrbB SW:YRBB_ECOLI (P45389) (129 aa) fasta scores: E(): 1.3e-25, 69.1% id in 97 aa. Also similar to several anti-sigma factor antagonists e.g. Listeria monocytogenes anti-sigma B factor antagonist RsbV SW:RSBV_LISMO (O85016) (114 aa) fasta scores: E(): 0.38, 25.6% id in 90 aa. (98 aa) |
| | STY3489 | Possible exported protein; Orthologue of E. coli yrbC (YRBC_ECOLI); Fasta hit to YRBC_ECOLI (211 aa), 94% identity in 211 aa overlap. Contains a possible N-terminal signal sequence. (211 aa) |
| | STY3490 | Possible exported protein; Orthologue of E. coli YRBD_ECOLI; Fasta hit to YRBD_ECOLI (183 aa), 87% identity in 183 aa overlap. Contains a possible N-terminal signal sequence. (183 aa) |
| | STY3491 | Putative membrane protein; Orthologue of E. coli yrbE (YRBE_ECOLI); Fasta hit to YRBE_ECOLI (260 aa), 96% identity in 260 aa overlap. Contains possible membrane spanning hydrophobic domains. (260 aa) |
| | STY3492 | Possible ABC-transport protein, ATP-binding component; Fasta hit to ARTP_ECOLI (242 aa), 30% identity in 234 aa overlap; Fasta hit to YHBG_ECOLI (240 aa), 33% identity in 228 aa overlap; Fasta hit to GLTL_ECOLI (241 aa), 30% identity in 242 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 31% identity in 228 aa overlap; Fasta hit to YECC_ECOLI (250 aa), 34% identity in 229 aa overlap; Fasta hit to GLNQ_ECOLI (240 aa), 32% identity in 245 aa overlap; Fasta hit to PSTB_ECOLI (257 aa), 31% identity in 256 aa overlap; Orthologue of E. coli YRBF_ECOLI; Fasta hit to YRBF_ECOLI (269 aa), 95% ide [...] (270 aa) |
| | STY3493 | Putative membrane protein; Similar to Escherichia coli hypothetical protein YrbG SW:YRBG_ECOLI (P45394) (325 aa) fasta scores: E(): 0, 87.3% id in 324 aa. Also similar in parts to Eukaryotic sodium/calcium exchange proteins e.g. Drosophila melanogaster potassium-dependent sodium/calcium exchanger TR:Q9U6A0 (EMBL:AF190455) (856 aa) fasta scores: E(): 9.2e-07, 30.1% id in 153 aa. Contains multiple possible membrane spanning hydrophobic domains; Orthologue of E. coli yrbG (YRBG_ECOLI); Fasta hit to YRBG_ECOLI (325 aa), 87% identity in 324 aa overlap. (325 aa) |
| | STY3494 | Conserved hypothetical protein; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity). (328 aa) |
| | STY3495 | Conserved hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate in vitro. Also catalyzes the dephosphorylation of phospho- tyrosine in vitro; Belongs to the KdsC family. (188 aa) |
| | STY3496 | Possible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa) |
| | STY3497 | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (172 aa) |
| | STY3498 | Probable ABC transport protein, ATP-binding component; Fasta hit to ARTP_ECOLI (242 aa), 30% identity in 212 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 30% identity in 203 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 33% identity in 233 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 35% identity in 229 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 31% identity in 237 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 32% identity in 238 aa overlap; Fasta hit to LIVG_ECOLI (255 aa), 32% identity in 249 aa overlap; Fasta hit to FTSE_ECOLI (222 aa), 30% identity in 216 aa overlap; Fasta hit [...] (241 aa) |
| | STY3502 | Conserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (284 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (242 aa) |
| | STY3506 | Conserved hypothetical protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. (217 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (156 aa) |
| | STY3549 | Possible exported protein; This CDS is similar to two adjoining E. coli hypothetical proteins. The N-terminus is similar to yhdR SW:YHDR_ECOLI (P46476) (282 aa) fasta scores: E(): 0, 82.0% id in 272 aa and the C-terminus is similar to yhdP SW:YHDP_ECOLI (P46474; P76676; P46475) (986 aa) fasta scores: E(): 0, 79.9% id in 987 aa. Contains a possible N-terminal signal sequence. (1266 aa) |
| | rnG | Ribonuclease G; Similar to Escherichia coli ribonuclease G cafA r rnG SW:RNG_ECOLI (P25537; P76677) (488 aa) fasta scores: E(): 0, 96.7% id in 488 aa. (489 aa) |
| | STY3551 | Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (197 aa) |
| | STY3552 | Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (163 aa) |
| | STY3553 | Rod shape-determining protein; Involved in formation and maintenance of cell shape. (350 aa) |
| | mreB | Rod shape-determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature. (347 aa) |
| | tatD | Putative deoxyribonuclease; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. (260 aa) |
| | tatC | Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (259 aa) |
| | tatB | Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (182 aa) |
| | tatA | Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (84 aa) |
| | STY3707 | Conserved hypothetical protein; Orthologue of E. coli yifE (YIFE_ECOLI); Fasta hit to YIFE_ECOLI (111 aa), 96% identity in 111 aa overlap; Belongs to the UPF0438 family. (112 aa) |
| | STY3714 | Conserved hypothetical protein; Orthologue of E. coli yjaH (YJAH_ECOLI); Fasta hit to YJAH_ECOLI (231 aa), 77% identity in 231 aa overlap. (230 aa) |
| | STY3715 | Histone like DNA-binding protein HU-alpha (NS2) (HU-2); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. (90 aa) |
| | STY3716 | Conserved hypothetical protein; Orthologue of E. coli YjaG (YJAG_ECOLI); Fasta hit to YJAG_ECOLI (196 aa), 95% identity in 196 aa overlap; To H.influenzae HI_0431. (196 aa) |
| | nfi | Putative endonuclease; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (223 aa) |
| | STY3742 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (342 aa) |
| | STY3743 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (260 aa) |
| | STY3747 | Possible TetR-family trancriptional regulatory protein; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (211 aa) |
| | STY3763 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (368 aa) |
| | STY3781 | Menaquinone biosynthesis protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. (161 aa) |
| | STY3878 | Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. (171 aa) |
| | radC | Similar to Escherichia coli DNA repair protein RadC radC SW:RADC_ECOLI (P25531) (222 aa) fasta scores: E(): 0, 83.7% id in 215 aa, and to Haemophilus influenzae DNA repair protein SW:RADC_HAEIN (P44952) (234 aa) fasta scores: E(): 0, 51.2% id in 217 aa; Belongs to the UPF0758 family. YicR subfamily. (221 aa) |
| | STY4070 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa) |
| | STY4089 | Putative exported protein; Similar to Escherichia coli hypothetical 30.7 kDa protein in secB-tdh intergenic region yibQ SW:YIBQ_ECOLI (P37691) (277 aa) fasta scores: E(): 0, 81.4% id in 279 aa, and to Haemophilus influenzae hypothetical protein Hi0755 hi0755 SW:YIBQ_HAEIN (P44863) (280 aa) fasta scores: E(): 9.3e-33, 41.0% id in 271 aa. (320 aa) |
| | STY4090 | Similar to Escherichia coli hypothetical 46.6 kDa protein in secB-tdh intergenic region yibP SW:YIBP_ECOLI (P37690) (419 aa) fasta scores: E(): 0, 91.6% id in 419 aa, and to Haemophilus influenzae hypothetical protein Hi0756 hi0756 SW:YIBP_HAEIN (P44864) (410 aa) fasta scores: E(): 0, 41.7% id in 403 aa. Contains coiled-coil regions. (427 aa) |
| | STY4092 | Putative secreted protein; Similar to Escherichia coli hypothetical 15.6 kDa protein in secB-tdh intergenic region yibN SW:YIBN_ECOLI (P37688) (143 aa) fasta scores: E(): 0, 93.7% id in 143 aa, and to Haemophilus influenzae hypothetical protein Hi0744 hi0744 SW:YIBN_HAEIN (P44854) (148 aa) fasta scores: E(): 1.4e-26, 49.7% id in 145 aa. (143 aa) |
| | STY4093 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (83 aa) |
| | secB | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (155 aa) |
| | STY4238 | Putative membrane protein; Similar to Escherichia coli hypothetical 10.3 kDa protein in ftsY-nikA intergenic region YhhL SW:YHHL_ECOLI (P37614) (89 aa) fasta scores: E(): 4.4e-32, 85.4% id in 89 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (90 aa) |
| | STY4239 | Conserved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (198 aa) |
| | ftsE | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (222 aa) |
| | ftsX | Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (351 aa) |
| | STY4292 | Possible RNA binding protein. Similar to Bordetella pertussis transcription accessory tex protein SW:TEX_BORPE (Q45388) (791 aa) fasta scores: E(): 0, 60.7% id in 768 aa, and to Escherichia coli 85.1 kDa protein in greB-feoA intergenic region YhgF SW:YHGF_ECOLI (P46837) (773 aa) fasta scores: E(): 0, 94.1% id in 776 aa. (776 aa) |
| | mrcA | Similar to Escherichia coli penicillin-binding protein 1A mrca or ponA SW:PBPA_ECOLI (P02918) (850 aa) fasta scores: E(): 0, 92.5% id in 850 aa, and to Pseudomonas aeruginosa penicillin-binding protein 1A ponA TR:Q07806 (EMBL:U73780) (822 aa) fasta scores: E(): 0, 42.1% id in 860 aa. (858 aa) |
| | prkB | Phosphoribulokinase; Similar to Escherichia coli probable phosphoribulokinase prkB SW:KPPR_ECOLI (P37307) (289 aa) fasta scores: E(): 0, 97.2% id in 289 aa, and to Alcaligenes eutrophus phosphoribulokinase, plasmid cfxP SW:KPPP_ALCEU (P19924) (291 aa) fasta scores: E(): 0, 57.1% id in 287 aa. (289 aa) |
| | yheU | Similar to Haemophilus influenzae hypothetical protein HI0956 SW:YHEU_HAEIN (P44954) (56 aa) fasta scores: E(): 1.2e-06, 65.8% id in 38 aa; Orthologue of E. coli yheU (YHEU_ECOLI); Fasta hit to YHEU_ECOLI (72 aa), 88% identity in 72 aa overlap; Belongs to the UPF0270 family. (72 aa) |
| | slyX | Conserved hypothetical protein; Similar to Escherichia coli SlyX protein slyX SW:SLYX_ECOLI (P30857) (72 aa) fasta scores: E(): 2.8e-25, 93.1% id in 72 aa, and to Haemophilus influenzae slyx protein homolog slyx or hi0573 SW:SLYX_HAEIN (P44759) (73 aa) fasta scores: E(): 4.1e-10, 49.3% id in 67 aa; Belongs to the SlyX family. (72 aa) |
| | fkpA | Similar to Escherichia coli fkbp-type peptidyl-prolyl cis-trans isomerase FkpA precursor fkpA SW:FKBA_ECOLI (P45523) (270 aa) fasta scores: E(): 0, 89.7% id in 272 aa, and to Aeromonas hydrophila fkbp-type peptidyl-prolyl cis-trans isomerase FkpA precursor fkpA SW:FKBA_AERHY (O08437) (268 aa) fasta scores: E(): 0, 44.0% id in 266 aa. (272 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis (By similarity). (359 aa) |
| | amiB | Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase amib precursor SW:AMIB_ECOLI (P26365) (445 aa) fasta scores: E(): 0, 83.7% id in 435 aa. (439 aa) |
| | yjga | Similar to Escherichia coli hypothetical 21.4 kDa protein in fbp-pmba intergenic region yjga or x96 SW:YJGA_ECOLI (P26650) (183 aa) fasta scores: E(): 0, 95.1% id in 183 aa, and to Haemophilus influenzae hypothetical protein Hi1151 hi1151 SW:YJGA_HAEIN (P45076) (178 aa) fasta scores: E(): 1e-31, 61.6% id in 164 aa; Belongs to the UPF0307 family. (183 aa) |
| | STY4808 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. (138 aa) |
| | STY4817 | Probable inner membrane protein. Similar to Escherichia coli hypothetical protein YjgP SW:YJGP_ECOLI (P39340) (366 aa) fasta scores: E(): 0, 95.3% id in 359 aa and to Haemophilus influenzae hypothetical protein HI1704 SW:YJGP_HAEIN (P45333) (372 aa) fasta scores: E(): 0, 47.8% id in 358 aa. (366 aa) |
| | STY4818 | Probable inner membrane protein. Similar to Escherichia coli hypothetical 39.8 kDa protein in pepA-gntV intergenic region YjgQ SW:YJGQ_ECOLI (P39341) (361 aa) fasta scores: E(): 0, 96.9% id in 360 aa, and to Haemophilus influenzae hypothetical protein HI1703 HI1703 SW:YJGQ_HAEIN (P45332) (358 aa) fasta scores: E(): 0, 53.8% id in 353 aa. (360 aa) |
| | slt | Similar to Escherichia coli soluble lytic murein transglycosylase precursor slt or sltY SW:SLT_ECOLI (P03810; P76820) (645 aa) fasta scores: E(): 0, 91.2% id in 627 aa. (627 aa) |
