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| | STY0052 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa) |
| | STY0055 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (944 aa) |
| | STY0210 | glutamyl-tRNA synthetase-related protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (298 aa) |
| | STY0239 | 30S ribosomal protein S2; Orthologue of E. coli rpsB (RS2_ECOLI); Fasta hit to RS2_ECOLI (240 aa), 98% identity in 240 aa overlap; Belongs to the universal ribosomal protein uS2 family. (241 aa) |
| | STY0240 | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (283 aa) |
| | STY0242 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | STY0265 | Putative release factor; Similar to Escherichia coli hypothetical 15.6 kDa protein in mesj-cutf intergenic region yaeJ SW:YAEJ_ECOLI (P40711) (140 aa) fasta scores: E(): 0, 84.6% id in 136 aa, and to Pseudomonas putida hypothetical 15.2 kDa protein in pcaj 3'region SW:YAEJ_PSEPU (P45388) (137 aa) fasta scores: E(): 9.5e-27, 57.0% id in 135 aa and to Salmonella typhimurium peptide chain release factor 2 prfB SW:RF2_SALTY (P28353) (365 aa) fasta scores: E(): 0.45, 29.6% id in 108 aa; Orthologue of E. coli yaeJ (YAEJ_ECOLI); Fasta hit to YAEJ_ECOLI (140 aa), 85% identity in 136 aa overlap. (140 aa) |
| | STY0269 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa) |
| | prfH | Similar to Escherichia coli peptide chain release factor homologue prfH SW:RFH_ECOLI (P28369; P77246) (141 aa) fasta scores: E(): 0, 81.9% id in 138 aa, and to Treponema pallidum peptide chain release factor 2 PrfB SW:RF2_TREPA (O83585) (368 aa) fasta scores: E(): 2.8e-12, 33.0% id in 206 aa, and to Haemophilus influenzae peptide chain release factor 2 prfb or hi1212 SW:RF2_HAEIN (P43918) (365 aa) fasta scores: E(): 9.8e-10, 37.2% id in 129 aa. (204 aa) |
| | rpmE2 | Putative 50s ribosomal protein L31 (second copy); Similar to Escherichia coli hypothetical 9.9 kDa protein in intf-eaeh intergenic region ykgM SW:YKGM_ECOLI (P71302) (87 aa) fasta scores: E(): 1.6e-27, 74.4% id in 86 aa, and to Listeria monocytogenes 50s ribosomal protein l31 rpmE SW:RL31_LISMO (Q9ZH28) (81 aa) fasta scores: E(): 7.9e-12, 48.1% id in 79 aa, and to Borrelia burgdorferi 50s ribosomal protein l31 rpme or bb0229 SW:RL31_BORBU (O51247) (81 aa) fasta scores: E(): 7.8e-11, 43.6% id in 78 aa; Fasta hit to RL31_ECOLI (70 aa), 33% identity in 84 aa overlap; Orthologue of E. coli [...] (86 aa) |
| | STY0513 | Similar to Guillardia theta chloroplast 50s ribosomal protein l36 rpl36 SW:RK36_GUITH (P28528; O46911) (48 aa) fasta scores: E(): 1.6e-09, 56.5% id in 46 aa, and to Rickettsia prowazekii 50s ribosomal protein l36 rpmj or rp456 SW:RL36_RICPR (Q9ZD87) (41 aa) fasta scores: E(): 4.9e-08, 56.1% id in 41 aa. (46 aa) |
| | STY0541 | Conserved hypothetical protein; Orthologue of E. coli YBAK_ECOLI; Fasta hit to YBAK_ECOLI (159 aa), 91% identity in 159 aa overlap; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | STY0585 | cysteinyl-tRNA synthetase; Orthologue of E. coli cysS (SYC_ECOLI); Fasta hit to SYC_ECOLI (461 aa), 94% identity in 461 aa overlap; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | STY0699 | leucyl-tRNA synthetase; Orthologue of E. coli leuS (SYL_ECOLI); Fasta hit to SYL_ECOLI (860 aa), 95% identity in 860 aa overlap; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | STY0724 | glutaminyl-tRNA synthetase; Orthologue of E. coli glnS (SYQ_ECOLI); Fasta hit to SYQ_ECOLI (553 aa), 96% identity in 554 aa overlap. (555 aa) |
| | STY0908 | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. (300 aa) |
| | STY0951 | Initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | STY0961 | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | STY0981 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (557 aa) |
| | asnS | Similar to Escherichia coli asparaginyl-tRNA synthetase SW:SYN_ECOLI (P17242) fasta scores: E(): 0, 94.6% id in 465 aa. (466 aa) |
| | STY1230 | 50S ribosomal protein L32; Orthologue of E. coli rpmF (RL32_ECOLI); Fasta hit to RL32_ECOLI (56 aa), 100% identity in 56 aa overlap; Belongs to the bacterial ribosomal protein bL32 family. (57 aa) |
| | STY1345 | Similar to Archaeoglobus fulgidus protein translation factor sui1 homolog af0914 SW:SUI1_ARCFU (O29348) (101 aa) fasta scores: E(): 4.5e-05, 47.5% id in 59 aa; Orthologue of E. coli yciH (YCIH_ECOLI); Fasta hit to YCIH_ECOLI (108 aa), 90% identity in 108 aa overlap; Belongs to the SUI1 family. (108 aa) |
| | STY1495 | 30S ribosomal protein S22; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family. (47 aa) |
| | STY1673 | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa) |
| | STY1772 | phenylalanyl-tRNA synthetase beta chain; Orthologue of E. coli pheT (SYFB_ECOLI); Fasta hit to SYFB_ECOLI (795 aa), 92% identity in 795 aa overlap; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa) |
| | STY1773 | phenylalanyl-tRNA synthetase alpha chain; Orthologue of E. coli pheS (SYFA_ECOLI); Fasta hit to SYFA_ECOLI (327 aa), 98% identity in 327 aa overlap; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa) |
| | STY1775 | 50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). (118 aa) |
| | STY1776 | 50S ribosomal subunit protein L35; Orthologue of E. coli rpmI (RL35_ECOLI); Fasta hit to RL35_ECOLI (64 aa), 100% identity in 64 aa overlap; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (180 aa) |
| | STY1778 | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (642 aa) |
| | prfA | Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | STY1909 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death. (202 aa) |
| | STY2019 | Putative bacteriophage protein; Unknown function. C-terminus is similar to that of bacteriophage phi CTX ORF16 TR:Q9ZXL0 (EMBL:AB008550) (190 aa) fasta scores: E(): 0.0033, 39.4% id in 99 aa. (251 aa) |
| | STY2109 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa) |
| | STY2117 | arginyl-tRNA synthetase; Orthologue of E. coli argS (SYR_ECOLI); Fasta hit to SYR_ECOLI (577 aa), 95% identity in 577 aa overlap. (577 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa) |
| | STY2460 | Putative helicase; Orthologue of E. coli yejH (YEJH_ECOLI); Fasta hit to YEJH_ECOLI (586 aa), 95% identity in 586 aa overlap. (586 aa) |
| | STY2461 | 50s ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) |
| | STY2654 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (474 aa) |
| | STY2767 | Similar to Salmonella typhimurium histidyl-tRNA synthetase SW:SYH_SALTY (O52765) (423 aa) fasta scores: E(): 0, 99.3% id in 423 aa; Orthologue of E. coli hisS (SYH_ECOLI); Fasta hit to SYH_ECOLI (423 aa), 95% identity in 423 aa overlap. (424 aa) |
| | STY2829 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | STY2860 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | STY2863 | 30S ribosomal subunit protein S16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity. (82 aa) |
| | STY2874 | SsrA (tmRNA)-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then swi [...] (160 aa) |
| | STY2948 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (876 aa) |
| | STY3196 | Lysyl tRNA synthetase (LysRS); Fasta hit to SYK2_ECOLI (504 aa), 90% identity in 504 aa overlap; Orthologue of E. coli lysS (SYK1_ECOLI); Fasta hit to SYK1_ECOLI (504 aa), 95% identity in 504 aa overlap; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | STY3197 | Peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (365 aa) |
| | STY3388 | 30S ribosomal subunit protein S21; Orthologue of E. coli rpsU (RS21_ECOLI); Fasta hit to RS21_ECOLI (70 aa), 100% identity in 70 aa overlap; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | STY3464 | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | STY3467 | Protein chain initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (892 aa) |
| | STY3482 | 50S ribosomal subunit protein L27; Orthologue of E. coli rpmA (RL27_ECOLI); Fasta hit to RL27_ECOLI (84 aa), 95% identity in 84 aa overlap; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | STY3483 | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | STY3524 | 30S ribosomal subunit protein S9; Orthologue of E. coli rpsI (RS9_ECOLI); Fasta hit to RS9_ECOLI (129 aa), 99% identity in 129 aa overlap; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | STY3525 | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | STY3733 | 50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. (121 aa) |
| | STY3734 | 50S ribosomal subunit protein L10; Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA (By similarity); Belongs to the universal ribosomal protein uL10 family. (165 aa) |
| | STY3735 | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | STY3736 | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa) |
| | tufB | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | STY3774 | 50S ribosomal protein L31; Binds the 23S rRNA. (70 aa) |
| | rpmH | Similar to Escherichia coli 50s ribosomal protein l34 RpmH SW:RL34_ECOLI (P02437) (46 aa) fasta scores: E(): 1.5e-19, 100.0% id in 46 aa; Belongs to the bacterial ribosomal protein bL34 family. (46 aa) |
| | STY4066 | 50S ribosomal subunit protein L28; Orthologue of E. coli rpmB (RL28_ECOLI); Fasta hit to RL28_ECOLI (77 aa), 96% identity in 77 aa overlap; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | STY4067 | 50S ribosomal subunit protein L33; Orthologue of E. coli rpmG (RL33_ECOLI); Fasta hit to RL33_ECOLI (54 aa), 100% identity in 54 aa overlap; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | STY4113 | L-seryl-tRNA(Ser) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa) |
| | STY4114 | Selenocysteine-specific elongation factor; Orthologue of E. coli selB (SELB_ECOLI); Fasta hit to SELB_ECOLI (614 aa), 85% identity in 615 aa overlap. (616 aa) |
| | STY4143 | glycine-tRNA synthetase, alpha subunit; Orthologue of E. coli glyQ (SYGA_ECOLI); Fasta hit to SYGA_ECOLI (303 aa), 99% identity in 303 aa overlap. (303 aa) |
| | STY4144 | glycine-tRNA synthetase, beta subunit; Orthologue of E. coli glyS (SYGB_ECOLI); Fasta hit to SYGB_ECOLI (688 aa), 94% identity in 688 aa overlap. (689 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa) |
| | rpsL | 30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa) |
| | rpsG | 30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (704 aa) |
| | tufA | Elongation factor Tu; Identical to Salmonella typhimurium elongation factor Tu tufa and tufB SW:EFTU_SALTY (P21694) (393 aa) fasta scores: E(): 0, 100.0% id in 393 aa, and to Escherichia coli elongation factor tu SW:EFTU_ECOLI (P02990) (393 aa) fasta scores: E(): 0, 99.7% id in 392 aa. (394 aa) |
| | rpsJ | 30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | rplC | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | rplD | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. (201 aa) |
| | rplW | 50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | 50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa) |
| | rpsS | 30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | rplV | 50S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (110 aa) |
| | rpsC | 30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity). Belongs to the universal ribosomal protein uS3 family. (233 aa) |
| | rplP | 50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpmC | 50S ribosomal subunit protein L29; Orthologue of E. coli rpmC (RL29_ECOLI); Fasta hit to RL29_ECOLI (63 aa), 98% identity in 63 aa overlap; Belongs to the universal ribosomal protein uL29 family. (63 aa) |
| | rpsQ | 30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rplN | 50S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa) |
| | rplX | 50S ribosomal subunit protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa) |
| | rplE | 50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rpsN | 30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rpsH | 30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rplF | 50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rplR | 50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rpsE | 30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (167 aa) |
| | rpmD | 50S ribosomal subunit protein L30; Orthologue of E. coli rpmD (RL30_ECOLI); Fasta hit to RL30_ECOLI (58 aa), 97% identity in 58 aa overlap. (59 aa) |
| | rplO | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) |
| | rpmJ | 50S ribosomal subunit protein L36; Orthologue of E. coli rpmJ (RL36_ECOLI); Fasta hit to RL36_ECOLI (38 aa), 100% identity in 38 aa overlap; Belongs to the bacterial ribosomal protein bL36 family. (38 aa) |
| | rpsM | 30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa) |
| | rpsK | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsD | 30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rplQ | 50S ribosomal subunit protein L17; Orthologue of E. coli rplQ (RL17_ECOLI); Fasta hit to RL17_ECOLI (127 aa), 99% identity in 127 aa overlap. (127 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. (315 aa) |
| | fms | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (169 aa) |
| | efp | Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa) |
| | STY4704 | lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta- lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF- P 'Lys-34'; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (325 aa) |
| | rpsF | 30s ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (131 aa) |
| | rpsR | 30s ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rplI | 50s ribosomal subunit protein L9; Binds to the 23S rRNA. (149 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (951 aa) |
| | trpS2 | Similar to Clostridium longisporum tryptophanyl-tRNA synthetase TrpS or TrsA SW:SYW_CLOLO (Q46127) (341 aa) fasta scores: E(): 0, 54.8% id in 330 aa, and to Thermotoga maritima tryptophanyl-tRNA synthetase TrpS SW:SYW_THEMA (Q9WYW2) (328 aa) fasta scores: E(): 0, 36.5% id in 329 aa. Note that the E.coli trpS ortholog is STY4315; Belongs to the class-I aminoacyl-tRNA synthetase family. (337 aa) |
| | STY4910 | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | STY4928 | Similar to Escherichia coli ABC transporter ATP-binding protein YjjK SW:YJJK_ECOLI (P37797) (554 aa) fasta scores: E(): 0, 97.1% id in 554 aa, and to Haemophilus influenzae ABC transporter ATP-binding protein HI1252 SW:YJJK_HAEIN (P45127) (556 aa) fasta scores: E(): 0, 86.8% id in 554 aa. (555 aa) |
