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| | STY4910 | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | STY0052 | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa) |
| | STY0055 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (944 aa) |
| | citX2 | Citx protein; Similar to Escherichia coli citx protein CITX SW:CITX_ECOLI (P77563) fasta scores: E(): 1.5e-26, 43.9% id in 164 aa, and to Leuconostoc mesenteroides citg protein CITG SW:CITG_LEUMC (O53080) fasta scores: E(): 1.1e-11, 28.5% id in 179 aa; Paralogue of E. coli CITX_ECOLI; Fasta hit to CITX_ECOLI (183 aa), 44% identity in 164 aa overlap. (183 aa) |
| | STY0078 | Transcriptional activator CaiF; Orthologue of E. coli caiF (CAIF_ECOLI); Fasta hit to CAIF_ECOLI (131 aa), 76% identity in 131 aa overlap. (131 aa) |
| | STY0112 | DNA polymerase II; Orthologue of E. coli polB (DPO2_ECOLI); Fasta hit to DPO2_ECOLI (782 aa), 90% identity in 782 aa overlap. (783 aa) |
| | STY0142 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (588 aa) |
| | STY0143 | UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopim ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa) |
| | STY0144 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diami nopimelate--D-alan alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (452 aa) |
| | STY0145 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | STY0146 | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (438 aa) |
| | STY0147 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (414 aa) |
| | STY0148 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa) |
| | STY0149 | UDP-N-acetylmuramate:alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (491 aa) |
| | STY0150 | D-alanine:D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa) |
| | STY0210 | glutamyl-tRNA synthetase-related protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (298 aa) |
| | STY0215 | Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (840 aa) |
| | STY0239 | 30S ribosomal protein S2; Orthologue of E. coli rpsB (RS2_ECOLI); Fasta hit to RS2_ECOLI (240 aa), 98% identity in 240 aa overlap; Belongs to the universal ribosomal protein uS2 family. (241 aa) |
| | STY0240 | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (283 aa) |
| | STY0242 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | STY0244 | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (252 aa) |
| | STY0254 | DNA polymerase III, alpha chain; Orthologue of E. coli dnaE (DP3A_ECOLI); Fasta hit to DP3A_ECOLI (1160 aa), 97% identity in 1160 aa overlap. (1160 aa) |
| | STY0265 | Putative release factor; Similar to Escherichia coli hypothetical 15.6 kDa protein in mesj-cutf intergenic region yaeJ SW:YAEJ_ECOLI (P40711) (140 aa) fasta scores: E(): 0, 84.6% id in 136 aa, and to Pseudomonas putida hypothetical 15.2 kDa protein in pcaj 3'region SW:YAEJ_PSEPU (P45388) (137 aa) fasta scores: E(): 9.5e-27, 57.0% id in 135 aa and to Salmonella typhimurium peptide chain release factor 2 prfB SW:RF2_SALTY (P28353) (365 aa) fasta scores: E(): 0.45, 29.6% id in 108 aa; Orthologue of E. coli yaeJ (YAEJ_ECOLI); Fasta hit to YAEJ_ECOLI (140 aa), 85% identity in 136 aa overlap. (140 aa) |
| | STY0269 | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa) |
| | STY0275 | Conserved hypothetical protein; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position in vitro. Also catalyzes the dephosphorylation of D-glycero-alpha-D-manno-heptose 1,7- bisphosphate and 2-deoxy-D-manno-2-octoulosonate-8-phosphate in vitro. Belongs to the GmhB family. (188 aa) |
| | STY0285 | DNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contains the editing function and is a proofreading 3'- 5' exonuclease (By similarity). (243 aa) |
| | STY0355 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (192 aa) |
| | STY0357 | Putative exported protein; Orthologue of E. coli yafK (YAFK_ECOLI); Fasta hit to YAFK_ECOLI (246 aa), 91% identity in 246 aa overlap. (246 aa) |
| | STY0358 | Hypothetical protein DinP (DNA damage-inducible protein); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (351 aa) |
| | prfH | Similar to Escherichia coli peptide chain release factor homologue prfH SW:RFH_ECOLI (P28369; P77246) (141 aa) fasta scores: E(): 0, 81.9% id in 138 aa, and to Treponema pallidum peptide chain release factor 2 PrfB SW:RF2_TREPA (O83585) (368 aa) fasta scores: E(): 2.8e-12, 33.0% id in 206 aa, and to Haemophilus influenzae peptide chain release factor 2 prfb or hi1212 SW:RF2_HAEIN (P43918) (365 aa) fasta scores: E(): 9.8e-10, 37.2% id in 129 aa. (204 aa) |
| | STY0412 | D-alanine:D-alanine ligase A; Cell wall formation. (364 aa) |
| | STY0457 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (139 aa) |
| | rpmE2 | Putative 50s ribosomal protein L31 (second copy); Similar to Escherichia coli hypothetical 9.9 kDa protein in intf-eaeh intergenic region ykgM SW:YKGM_ECOLI (P71302) (87 aa) fasta scores: E(): 1.6e-27, 74.4% id in 86 aa, and to Listeria monocytogenes 50s ribosomal protein l31 rpmE SW:RL31_LISMO (Q9ZH28) (81 aa) fasta scores: E(): 7.9e-12, 48.1% id in 79 aa, and to Borrelia burgdorferi 50s ribosomal protein l31 rpme or bb0229 SW:RL31_BORBU (O51247) (81 aa) fasta scores: E(): 7.8e-11, 43.6% id in 78 aa; Fasta hit to RL31_ECOLI (70 aa), 33% identity in 84 aa overlap; Orthologue of E. coli [...] (86 aa) |
| | STY0513 | Similar to Guillardia theta chloroplast 50s ribosomal protein l36 rpl36 SW:RK36_GUITH (P28528; O46911) (48 aa) fasta scores: E(): 1.6e-09, 56.5% id in 46 aa, and to Rickettsia prowazekii 50s ribosomal protein l36 rpmj or rp456 SW:RL36_RICPR (Q9ZD87) (41 aa) fasta scores: E(): 4.9e-08, 56.1% id in 41 aa. (46 aa) |
| | STY0528 | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (642 aa) |
| | STY0541 | Conserved hypothetical protein; Orthologue of E. coli YBAK_ECOLI; Fasta hit to YBAK_ECOLI (159 aa), 91% identity in 159 aa overlap; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | STY0585 | cysteinyl-tRNA synthetase; Orthologue of E. coli cysS (SYC_ECOLI); Fasta hit to SYC_ECOLI (461 aa), 94% identity in 461 aa overlap; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | gtrA | Bactoprenol-linked glucose translocase; Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane. (120 aa) |
| | STY0669 | Conserved hypothetical protein; Similar to, but shorter than Escherichia coli CitX protein SW:CITX_ECOLI (P77563) (183 aa) fasta scores: E(): 0, 74.8% id in 135 aa, and to the N-terminus of Haemophilus influenzae citg protein HI0021 SW:CITG_HAEIN (P44458) (416 aa) fasta scores: E(): 1.1e-11, 33.1% id in 130 aa. (139 aa) |
| | STY0688 | D-alanine carboxypeptidase; Fasta hit to DACC_ECOLI (400 aa), 60% identity in 401 aa overlap; Fasta hit to DACD_ECOLI (388 aa), 48% identity in 390 aa overlap; Orthologue of E. coli dacA (DACA_ECOLI); Fasta hit to DACA_ECOLI (403 aa), 95% identity in 403 aa overlap; Belongs to the peptidase S11 family. (403 aa) |
| | STY0690 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa) |
| | pbpA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (633 aa) |
| | STY0697 | DNA polymerase III, delta subunit; Orthologue of E. coli holA (HOLA_ECOLI); Fasta hit to HOLA_ECOLI (343 aa), 90% identity in 343 aa overlap. (343 aa) |
| | STY0699 | leucyl-tRNA synthetase; Orthologue of E. coli leuS (SYL_ECOLI); Fasta hit to SYL_ECOLI (860 aa), 95% identity in 860 aa overlap; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | STY0711 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (512 aa) |
| | STY0724 | glutaminyl-tRNA synthetase; Orthologue of E. coli glnS (SYQ_ECOLI); Fasta hit to SYQ_ECOLI (553 aa), 96% identity in 554 aa overlap. (555 aa) |
| | ybiS | Putative exported protein; Similar to Escherichia coli protein YbiS precursor ybiS SW:YBIS_ECOLI (P75789) (306 aa) fasta scores: E(): 0, 92.5% id in 306 aa, and to Escherichia coli protein ErfK/srfk precursor erfK SW:ERFK_ECOLI (P39176) (310 aa) fasta scores: E(): 0, 65.8% id in 295 aa, and to Escherichia coli hypothetical 34.6 kDa protein in ndh-mfd intergenic region precursor ycfS SW:YCFS_ECOLI (P75954) (320 aa) fasta scores: E(): 0, 51.7% id in 302 aa. Contains probable N-terminal signal sequence; Fasta hit to YNHG_ECOLI (334 aa), 47% identity in 305 aa overlap; Fasta hit to YCFS_EC [...] (306 aa) |
| | STY0896 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6 precursor); Fasta hit to DACD_ECOLI (388 aa), 47% identity in 384 aa overlap; Fasta hit to DACA_ECOLI (403 aa), 61% identity in 397 aa overlap; Orthologue of E. coli dacC (DACC_ECOLI); Fasta hit to DACC_ECOLI (400 aa), 92% identity in 400 aa overlap; Belongs to the peptidase S11 family. (400 aa) |
| | STY0908 | Ribosomal protein S6 modification protein; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. Belongs to the RimK family. (300 aa) |
| | STY0951 | Initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | STY0961 | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | STY0981 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (557 aa) |
| | STY0990 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (248 aa) |
| | STY0997 | Putative exported protein; Orthologue of E. coli ycbB (YCBB_ECOLI); Fasta hit to YCBB_ECOLI (615 aa), 85% identity in 618 aa overlap. (615 aa) |
| | asnS | Similar to Escherichia coli asparaginyl-tRNA synthetase SW:SYN_ECOLI (P17242) fasta scores: E(): 0, 94.6% id in 465 aa. (466 aa) |
| | STY1186 | Glucans biosynthesis protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (384 aa) |
| | STY1187 | Periplasmic glucans biosynthesis protein MdoG precursor; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (511 aa) |
| | STY1188 | Periplasmic glucans biosynthesis protein MdoH; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (847 aa) |
| | STY1192 | Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) (heat shock protein); Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) |
| | mviN | Virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (497 aa) |
| | STY1230 | 50S ribosomal protein L32; Orthologue of E. coli rpmF (RL32_ECOLI); Fasta hit to RL32_ECOLI (56 aa), 100% identity in 56 aa overlap; Belongs to the bacterial ribosomal protein bL32 family. (57 aa) |
| | STY1238 | Putative secreted protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (338 aa) |
| | STY1240 | DNA polymerase III, delta' subunit; Orthologue of E. coli holB (HOLB_ECOLI); Fasta hit to HOLB_ECOLI (334 aa), 79% identity in 334 aa overlap. (334 aa) |
| | STY1247 | Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. (212 aa) |
| | STY1249 | Putative glycosyl hydrolase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (341 aa) |
| | STY1255 | Putative exported protein; Fasta hit to ERFK_ECOLI (310 aa), 52% identity in 254 aa overlap; Fasta hit to YBIS_ECOLI (306 aa), 52% identity in 262 aa overlap; Orthologue of E. coli YCFS_ECOLI; Fasta hit to YCFS_ECOLI (320 aa), 87% identity in 263 aa overlap. Contains a possible N-terminal signal sequence. Short C-terminal truncation relative to E. coli. (263 aa) |
| | STY1301 | Thymidine kinase; Orthologue of E. coli tdk (KITH_ECOLI); Fasta hit to KITH_ECOLI (205 aa), 93% identity in 204 aa overlap. (205 aa) |
| | STY1345 | Similar to Archaeoglobus fulgidus protein translation factor sui1 homolog af0914 SW:SUI1_ARCFU (O29348) (101 aa) fasta scores: E(): 4.5e-05, 47.5% id in 59 aa; Orthologue of E. coli yciH (YCIH_ECOLI); Fasta hit to YCIH_ECOLI (108 aa), 90% identity in 108 aa overlap; Belongs to the SUI1 family. (108 aa) |
| | STY1442 | Putative exported protein; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs); Belongs to the OpgD/OpgG family. (541 aa) |
| | STY1495 | 30S ribosomal protein S22; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family. (47 aa) |
| | STY1673 | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa) |
| | STY1772 | phenylalanyl-tRNA synthetase beta chain; Orthologue of E. coli pheT (SYFB_ECOLI); Fasta hit to SYFB_ECOLI (795 aa), 92% identity in 795 aa overlap; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa) |
| | STY1773 | phenylalanyl-tRNA synthetase alpha chain; Orthologue of E. coli pheS (SYFA_ECOLI); Fasta hit to SYFA_ECOLI (327 aa), 98% identity in 327 aa overlap; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa) |
| | STY1775 | 50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). (118 aa) |
| | STY1776 | 50S ribosomal subunit protein L35; Orthologue of E. coli rpmI (RL35_ECOLI); Fasta hit to RL35_ECOLI (64 aa), 100% identity in 64 aa overlap; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (180 aa) |
| | STY1778 | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (642 aa) |
| | rfc | O-antigen polymerase; May link the O-antigen tetrasaccharide units into long chains, giving rise to typical smooth LPS. (407 aa) |
| | STY1897 | 2-dehydro-3-deoxyphosphooctonate aldolase; Orthologue of E. coli kdsA (KDSA_ECOLI); Fasta hit to KDSA_ECOLI (284 aa), 94% identity in 282 aa overlap; Belongs to the KdsA family. (284 aa) |
| | prfA | Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | STY1909 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death. (202 aa) |
| | ftsI2 | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa) |
| | STY2019 | Putative bacteriophage protein; Unknown function. C-terminus is similar to that of bacteriophage phi CTX ORF16 TR:Q9ZXL0 (EMBL:AB008550) (190 aa) fasta scores: E(): 0.0033, 39.4% id in 99 aa. (251 aa) |
| | STY2082 | DNA polymerase III, theta subunit; Orthologue of E. coli holE (HOLE_ECOLI); Fasta hit to HOLE_ECOLI (76 aa), 88% identity in 76 aa overlap. (76 aa) |
| | STY2097 | Lipid A acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (323 aa) |
| | STY2109 | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa) |
| | STY2117 | arginyl-tRNA synthetase; Orthologue of E. coli argS (SYR_ECOLI); Fasta hit to SYR_ECOLI (577 aa), 95% identity in 577 aa overlap. (577 aa) |
| | fliA | RNA polymerase sigma transcription factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (239 aa) |
| | STY2194 | Putative membrane protein; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity). (567 aa) |
| | STY2205 | UmuC protein; Similar to Salmonella typhimurium UmuC protein umuC SW:UMUC_SALTY (P22494) (422 aa) fasta scores: E(): 0, 98.8% id in 422 aa; Orthologue of E. coli umuC (UMUC_ECOLI); Fasta hit to UMUC_ECOLI (422 aa), 83% identity in 422 aa overlap; Belongs to the DNA polymerase type-Y family. (422 aa) |
| | STY2206 | UmuD protein; Similar to Salmonella typhimurium UmuD protein umuD SW:UMUD_SALTY (P22493) (139 aa) fasta scores: E(): 0, 99.3% id in 139 aa; Orthologue of E. coli umuD (UMUD_ECOLI); Fasta hit to UMUD_ECOLI (139 aa), 73% identity in 138 aa overlap; Belongs to the peptidase S24 family. (139 aa) |
| | STY2218 | Putative exported protein; Similar to Salmonella typhimurium protein erfK/srfK precursor SW:ERFK_SALTY (P40680) (309 aa) fasta scores: E(): 0, 99.0% id in 309 aa. Contains probable N-terminal signal sequence; Fasta hit to YNHG_ECOLI (334 aa), 47% identity in 288 aa overlap; Fasta hit to YCFS_ECOLI (320 aa), 48% identity in 307 aa overlap; Fasta hit to YBIS_ECOLI (306 aa), 66% identity in 283 aa overlap; Orthologue of E. coli erfK (ERFK_ECOLI); Fasta hit to ERFK_ECOLI (310 aa), 79% identity in 305 aa overlap. (309 aa) |
| | cld | Similar to Salmonella typhimurium chain length determinant protein wzzB or cld or rol SW:WZZB_SALTY (Q04866) (327 aa) fasta scores: E(): 0, 99.1% id in 327 aa. Contains hydrophobic, probable membrane-spanning regions; Orthologue of E. coli WZB1_ECOLI; Fasta hit to WZB1_ECOLI (326 aa), 72% identity in 326 aa overlap. (327 aa) |
| | ugd | Identical to Salmonella typhimurium UDP-glucose 6-dehydrogenase Ugd or Udg SW:UDG_SALTY (Q04873) (388 aa) fasta scores: E(): 0, 98.5% id in 388 aa; Orthologue of E. coli UDG_ECOLI; Fasta hit to UDG_ECOLI (388 aa), 88% identity in 388 aa overlap. (388 aa) |
| | rfbP | Similar to many e.g. Salmonella typhimurium undecaprenyl-phosphate galactosephosphotransferase rfbP SW:RFBP_SALTY (P26406) (476 aa) fasta scores: E(): 0, 98.3% id in 476 aa and Salmonella typhimurium galactosyl-1-phosphate transferase RFBP4452 TR:Q54016 (EMBL:U35435) (476 aa) fasta scores: E(): 0, 98.1% id in 476 aa. Contains hydrophobic, probable membrane-spanning regions. (476 aa) |
| | STY2293 | Similar to many e.g. Salmonella typhimurium mannose-1-phosphate guanylyltransferase SW:RFBM_SALTY (P26404) (479 aa) fasta scores: E(): 0, 98.7% id in 479 aa; Paralogue of E. coli cpsB (MANC_ECOLI); Fasta hit to MANC_ECOLI (478 aa), 59% identity in 469 aa overlap; Belongs to the mannose-6-phosphate isomerase type 2 family. (479 aa) |
| | rfbX | Putative O-antigen transporter; May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units. (432 aa) |
| | rfbE | CDP-tyvelose-2-epimerase; Catalyzes the isomeration of CDP-paratose to CDP-tyvelose. (338 aa) |
| | rfbS | Paratose synthase; Catalyzes synthesis of paratose and tyvelose, unusual 3,6- dideoxyhexose sugars that form part of the O-antigen in the lipopolysaccharides of several enteric bacteria; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (279 aa) |
| | rfbF | Glucose-1-phosphate cytidylyltransferase; Involved in the biosynthesis of the tyvelose, a 3,6- dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucleotide donor; Belongs to the glucose-1-phosphate cytidylyltransferase family. (257 aa) |
| | STY2305 | TDP-glucose pyrophosphorylase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (292 aa) |
| | STY2306 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (299 aa) |
| | STY2308 | UTP-glucose-1-phosphate uridylyltransferase; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family. (297 aa) |
| | manC | Similar to Salmonella typhimurium mannose-1-phosphate guanylyltransferase manC or cpsB or rfbM SW:MANC_SALTY (P26340) (480 aa) fasta scores: E(): 0, 99.8% id in 480 aa; Orthologue of E. coli cpsB (MANC_ECOLI); Fasta hit to MANC_ECOLI (478 aa), 91% identity in 478 aa overlap; Belongs to the mannose-6-phosphate isomerase type 2 family. (480 aa) |
| | wzc | Putative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family. (719 aa) |
| | wzb | Putative protein-tyrosine phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI). (149 aa) |
| | wza | Putative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. (379 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa) |
| | STY2449 | Putative membrane protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (239 aa) |
| | STY2460 | Putative helicase; Orthologue of E. coli yejH (YEJH_ECOLI); Fasta hit to YEJH_ECOLI (586 aa), 95% identity in 586 aa overlap. (586 aa) |
| | STY2461 | 50s ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) |
| | STY2527 | Putative lipopolysaccharide biosynthesis protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (385 aa) |
| | pmrF | Putative lipopolysaccharide modification protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (327 aa) |
| | STY2529 | Putative lipopolysaccharide modification protein; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (660 aa) |
| | STY2530 | Conserved hypothetical protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (299 aa) |
| | pqaB | Melittin resistance protein PqaB; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the glycosyltransferase 83 family. (548 aa) |
| | STY2532 | Putative membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (111 aa) |
| | STY2533 | Putative membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (125 aa) |
| | gtrA2 | Bactoprenol-linked glucose transferase; Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane. (129 aa) |
| | STY2639 | Putative acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (306 aa) |
| | STY2654 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (474 aa) |
| | STY2767 | Similar to Salmonella typhimurium histidyl-tRNA synthetase SW:SYH_SALTY (O52765) (423 aa) fasta scores: E(): 0, 99.3% id in 423 aa; Orthologue of E. coli hisS (SYH_ECOLI); Fasta hit to SYH_ECOLI (423 aa), 95% identity in 423 aa overlap. (424 aa) |
| | pbpC | Penicillin-binding protein 1C; Orthologue of E. coli PBPC_ECOLI; Fasta hit to PBPC_ECOLI (770 aa), 83% identity in 762 aa overlap. (771 aa) |
| | STY2829 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | STY2833 | RNA polymerase sigma-E factor (sigma-24); Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as acid stress, heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity). (191 aa) |
| | STY2860 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | STY2863 | 30S ribosomal subunit protein S16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity. (82 aa) |
| | STY2874 | SsrA (tmRNA)-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then swi [...] (160 aa) |
| | STY2879 | Putative reverse transcriptase; Shows very weak similarity to Escherichia coli RNA-directed DNA polymerase from retron EC86 SW:RT86_ECOLI (P23070) (320 aa) fasta scores: E(): 0.0026, 23.8% id in 210 aa. (257 aa) |
| | STY2948 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (876 aa) |
| | STY2960 | Putative phosphosugar binding protein; Catalyzes the reversible aldol-ketol isomerization between D- ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). It is also able of sustaining the biosynthetic pathway of 3-deoxy-D-manno- octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs) (By similarity). (321 aa) |
| | rpoS | RNA polymerase sigma subunit RpoS (sigma-38); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (330 aa) |
| | STY3143 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (291 aa) |
| | STY3173 | Hypothetical protein; No significant database hits. (170 aa) |
| | STY3196 | Lysyl tRNA synthetase (LysRS); Fasta hit to SYK2_ECOLI (504 aa), 90% identity in 504 aa overlap; Orthologue of E. coli lysS (SYK1_ECOLI); Fasta hit to SYK1_ECOLI (504 aa), 95% identity in 504 aa overlap; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | STY3197 | Peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (365 aa) |
| | rfaE | ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (477 aa) |
| | STY3384 | Bacitracin resistance protein (putative undecaprenol kinase); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (273 aa) |
| | STY3388 | 30S ribosomal subunit protein S21; Orthologue of E. coli rpsU (RS21_ECOLI); Fasta hit to RS21_ECOLI (70 aa), 100% identity in 70 aa overlap; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | STY3389 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (581 aa) |
| | STY3390 | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (660 aa) |
| | STY3447 | Possible exported protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. (683 aa) |
| | STY3464 | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | STY3467 | Protein chain initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (892 aa) |
| | STY3468 | L factor; Participates in both transcription termination and antitermination. (500 aa) |
| | STY3482 | 50S ribosomal subunit protein L27; Orthologue of E. coli rpmA (RL27_ECOLI); Fasta hit to RL27_ECOLI (84 aa), 95% identity in 84 aa overlap; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | STY3483 | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | STY3486 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | STY3494 | Conserved hypothetical protein; Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs). Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity). (328 aa) |
| | STY3495 | Conserved hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate in vitro. Also catalyzes the dephosphorylation of phospho- tyrosine in vitro; Belongs to the KdsC family. (188 aa) |
| | STY3499 | RNA polymerase sigma-54 factor (sigma-N); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (242 aa) |
| | STY3524 | 30S ribosomal subunit protein S9; Orthologue of E. coli rpsI (RS9_ECOLI); Fasta hit to RS9_ECOLI (129 aa), 99% identity in 129 aa overlap; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | STY3525 | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | STY3626 | Probable UDP-N-acetyl-D-mannosaminuronic acid transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. (246 aa) |
| | STY3627 | Probable 4-alpha-l-fucosyltransferase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. (452 aa) |
| | STY3628 | Conserved hypothetical protein; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. (359 aa) |
| | STY3629 | Putative lipopolysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. (416 aa) |
| | STY3630 | Lipopolysaccharide biosynthesis protein; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. (376 aa) |
| | STY3631 | Lipopolysaccharide biosynthesis protein; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. (182 aa) |
| | STY3632 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa) |
| | STY3634 | UDP-ManNAc dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa) |
| | wecB | UDP-N-acetyl-D-glucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa) |
| | STY3636 | Lipopolysaccharide biosynthesis protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (348 aa) |
| | STY3637 | Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (367 aa) |
| | STY3638 | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | STY3731 | DNA-directed RNA polymerase, beta'-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa) |
| | STY3732 | DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa) |
| | STY3733 | 50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. (121 aa) |
| | STY3734 | 50S ribosomal subunit protein L10; Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA (By similarity); Belongs to the universal ribosomal protein uL10 family. (165 aa) |
| | STY3735 | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | STY3736 | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa) |
| | STY3737 | Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Bel [...] (181 aa) |
| | tufB | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | STY3742 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (342 aa) |
| | STY3743 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (260 aa) |
| | STY4928 | Similar to Escherichia coli ABC transporter ATP-binding protein YjjK SW:YJJK_ECOLI (P37797) (554 aa) fasta scores: E(): 0, 97.1% id in 554 aa, and to Haemophilus influenzae ABC transporter ATP-binding protein HI1252 SW:YJJK_HAEIN (P45127) (556 aa) fasta scores: E(): 0, 86.8% id in 554 aa. (555 aa) |
| | STY3774 | 50S ribosomal protein L31; Binds the 23S rRNA. (70 aa) |
| | STY3775 | Primosomal protein replication factor; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa) |
| | STY3881 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (928 aa) |
| | STY3916 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (456 aa) |
| | rpmH | Similar to Escherichia coli 50s ribosomal protein l34 RpmH SW:RL34_ECOLI (P02437) (46 aa) fasta scores: E(): 1.5e-19, 100.0% id in 46 aa; Belongs to the bacterial ribosomal protein bL34 family. (46 aa) |
| | STY3941 | DNA polymerase III beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa) |
| | rpoZ | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). (91 aa) |
| | STY4066 | 50S ribosomal subunit protein L28; Orthologue of E. coli rpmB (RL28_ECOLI); Fasta hit to RL28_ECOLI (77 aa), 96% identity in 77 aa overlap; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | STY4067 | 50S ribosomal subunit protein L33; Orthologue of E. coli rpmG (RL33_ECOLI); Fasta hit to RL33_ECOLI (54 aa), 100% identity in 54 aa overlap; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | STY4070 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa) |
| | waaP | Lipopolysaccharide core biosynthesis protein; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family. (265 aa) |
| | waaB | Similar to Salmonella typhimurium lipopolysaccharide 1,6-galactosyltransferase rfab or waaB SW:RFAB_SALTY (Q06994) (359 aa) fasta scores: E(): 0, 98.1% id in 359 aa, and to Escherichia coli lipopolysaccharide 1,6-galactosyltransferase rfab or waaB SW:RFAB_ECOLI (P27127) (369 aa) fasta scores: E(): 0, 63.8% id in 359 aa. (359 aa) |
| | waaI | Similar to Salmonella typhimurium lipopolysaccharide 1,3-galactosyltransferase SW:RFAI_SALTY (P19816) (338 aa) fasta scores: E(): 0, 97.0% id in 338 aa, and to Escherichia coli lipopolysaccharide 1,3-galactosyltransferase SW:RFAI_ECOLI (P27128) (339 aa) fasta scores: E(): 0, 54.9% id in 337 aa. (337 aa) |
| | waaJ | Similar to Salmonella typhimurium lipopolysaccharide 1,2-glucosyltransferase SW:RFAJ_SALTY (P19817) (336 aa) fasta scores: E(): 0, 99.1% id in 336 aa, and to Escherichia coli lipopolysaccharide 1,2-glucosyltransferase SW:RFAJ_ECOLI (P27129) (338 aa) fasta scores: E(): 0, 58.4% id in 339 aa. (336 aa) |
| | waaK | Similar to Salmonella typhimurium lipopolysaccharide 1,2-N-acetylglucosaminetransferase SW:RFAK_SALTY (P26470) (381 aa) fasta scores: E(): 0, 99.2% id in 381 aa, and to Escherichia coli glcnac transferase waaK TR:O68201 (EMBL:AF019375) (380 aa) fasta scores: E(): 0, 73.6% id in 379 aa. (381 aa) |
| | waaC | Similar to Salmonella typhimurium lipopolysaccharide heptosyltransferase-1 rfaC or waaC SW:RFAC_SALTY (P26469) (317 aa) fasta scores: E(): 0, 98.7% id in 317 aa, and to Escherichia coli lipopolysaccharide heptosyltransferase-1 rfaC or waaC or rfa-2 SW:RFAC_ECOLI (P24173) (319 aa) fasta scores: E(): 0, 84.2% id in 316 aa. (317 aa) |
| | waaF | Similar to Salmonella typhimurium ADP-heptose-LPS heptosyltransferase II rfaF or waaF SW:RFAF_SALTY (P37421) (348 aa) fasta scores: E(): 0, 99.1% id in 348 aa, and to Escherichia coli ADP-heptose-LPS heptosyltransferase II rfaF or waaF SW:RFAF_ECOLI (P37692) (348 aa) fasta scores: E(): 0, 92.2% id in 346 aa. (348 aa) |
| | rfaD | ADP-L-Glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose. (310 aa) |
| | STY4108 | Hypothetical protein; Unknown function. (68 aa) |
| | STY4113 | L-seryl-tRNA(Ser) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa) |
| | STY4114 | Selenocysteine-specific elongation factor; Orthologue of E. coli selB (SELB_ECOLI); Fasta hit to SELB_ECOLI (614 aa), 85% identity in 615 aa overlap. (616 aa) |
| | STY4143 | glycine-tRNA synthetase, alpha subunit; Orthologue of E. coli glyQ (SYGA_ECOLI); Fasta hit to SYGA_ECOLI (303 aa), 99% identity in 303 aa overlap. (303 aa) |
| | STY4144 | glycine-tRNA synthetase, beta subunit; Orthologue of E. coli glyS (SYGB_ECOLI); Fasta hit to SYGB_ECOLI (688 aa), 94% identity in 688 aa overlap. (689 aa) |
| | yhjO | Putative polysaccharide biosynthesis protein catalytic subunit; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix (By similarity). (874 aa) |
| | STY4182 | Putative polysaccharide biosynthesis protein subunit B; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. (766 aa) |
| | rpoH | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (284 aa) |
| | glgB | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (728 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. (431 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (477 aa) |
| | mrcA | Similar to Escherichia coli penicillin-binding protein 1A mrca or ponA SW:PBPA_ECOLI (P02918) (850 aa) fasta scores: E(): 0, 92.5% id in 850 aa, and to Pseudomonas aeruginosa penicillin-binding protein 1A ponA TR:Q07806 (EMBL:U73780) (822 aa) fasta scores: E(): 0, 42.1% id in 860 aa. (858 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa) |
| | rpsL | 30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa) |
| | rpsG | 30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (704 aa) |
| | tufA | Elongation factor Tu; Identical to Salmonella typhimurium elongation factor Tu tufa and tufB SW:EFTU_SALTY (P21694) (393 aa) fasta scores: E(): 0, 100.0% id in 393 aa, and to Escherichia coli elongation factor tu SW:EFTU_ECOLI (P02990) (393 aa) fasta scores: E(): 0, 99.7% id in 392 aa. (394 aa) |
| | rpsJ | 30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | rplC | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | rplD | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. (201 aa) |
| | rplW | 50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | 50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa) |
| | rpsS | 30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | rplV | 50S ribosomal subunit protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (110 aa) |
| | rpsC | 30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity). Belongs to the universal ribosomal protein uS3 family. (233 aa) |
| | rplP | 50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpmC | 50S ribosomal subunit protein L29; Orthologue of E. coli rpmC (RL29_ECOLI); Fasta hit to RL29_ECOLI (63 aa), 98% identity in 63 aa overlap; Belongs to the universal ribosomal protein uL29 family. (63 aa) |
| | rpsQ | 30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rplN | 50S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa) |
| | rplX | 50S ribosomal subunit protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa) |
| | rplE | 50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rpsN | 30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rpsH | 30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rplF | 50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rplR | 50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rpsE | 30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (167 aa) |
| | rpmD | 50S ribosomal subunit protein L30; Orthologue of E. coli rpmD (RL30_ECOLI); Fasta hit to RL30_ECOLI (58 aa), 97% identity in 58 aa overlap. (59 aa) |
| | rplO | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) |
| | rpmJ | 50S ribosomal subunit protein L36; Orthologue of E. coli rpmJ (RL36_ECOLI); Fasta hit to RL36_ECOLI (38 aa), 100% identity in 38 aa overlap; Belongs to the bacterial ribosomal protein bL36 family. (38 aa) |
| | rpsM | 30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa) |
| | rpsK | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsD | 30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rpoA | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa) |
| | rplQ | 50S ribosomal subunit protein L17; Orthologue of E. coli rplQ (RL17_ECOLI); Fasta hit to RL17_ECOLI (127 aa), 99% identity in 127 aa overlap. (127 aa) |
| | zntR | Putative Zn(II)-responsive regulator; Similar to Escherichia coli zn zntR SW:ZNTR_ECOLI (P36676) (141 aa) fasta scores: E(): 0, 92.9% id in 141 aa. (141 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. (315 aa) |
| | fms | Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (169 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. (471 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis (By similarity). (359 aa) |
| | STY4522 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (454 aa) |
| | samB | UV protection protein; Similar to Salmonella typhimurium cryptic 60-MDa plasmid SamB protein SW:SAMB_SALTY (P23832) (424 aa) fasta scores: E(): 0, 89.6% id in 423 aa, and to Shigella flexneri ImpB impB TR:Q9ZA91 (EMBL:AF079316) (423 aa) fasta scores: E(): 0, 71.7% id in 421 aa; Paralogue of E. coli umuC (UMUC_ECOLI); Fasta hit to UMUC_ECOLI (422 aa), 63% identity in 420 aa overlap. (424 aa) |
| | tviE | Vi polysaccharide biosynthesis protein TviE, Glycosyl transferases group 1; Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipC or TviE SW:VIPC_SALTI (Q04975) (578 aa) fasta scores: E(): 0, 99.5% id in 578 aa. (578 aa) |
| | tviD | Vi polysaccharide biosynthesis protein; May be required for maturation of the Vi polysaccharide. (831 aa) |
| | tviC | Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipB or TviC SW:VIPB_SALTI (Q04973) (348 aa) fasta scores: E(): 0, 100.0% id in 348 aa, and to Pseudomonas aeruginosa WbpP TR:Q9RHD6 (EMBL:AF035937) (341 aa) fasta scores: E(): 0, 66.6% id in 338 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa) |
| | tviB | Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipA or TviB SW:VIPA_SALTI (Q04972) (425 aa) fasta scores: E(): 0, 99.8% id in 425 aa, and to Pseudomonas aeruginosa WbpO TR:Q9RHD7 (EMBL:AF035937) (422 aa) fasta scores: E(): 0, 66.8% id in 422 aa; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (425 aa) |
| | tviA | Similar to Salmonella typhi Vi polysaccharide biosynthesis protein TviA SW:TVIA_SALTI (Q04971) (179 aa) fasta scores: E(): 0, 100.0% id in 179 aa and to Salmonella paratyphi C VipR protein TR:BAA24231 (EMBL:AB006131) (179 aa) fasta scores: E(): 0, 100.0% id in 179 aa. (179 aa) |
| | efp | Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa) |
| | STY4704 | lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta- lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF- P 'Lys-34'; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (325 aa) |
| | rpsF | 30s ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (131 aa) |
| | priB | Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS). During primosome assembly it facilitates the complex formation between PriA and DnaT; Belongs to the PriB family. (104 aa) |
| | rpsR | 30s ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rplI | 50s ribosomal subunit protein L9; Binds to the 23S rRNA. (149 aa) |
| | mpl | Murein peptide ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (457 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (951 aa) |
| | holC | Similar to Escherichia coli DNA polymerase III, chi subunit HolC SW:HOLC_ECOLI (P28905) (147 aa) fasta scores: E(): 0, 95.2% id in 147 aa and to Haemophilus influenzae DNA polymerase III, chi subunit HolC SW:HOLC_HAEIN (P43749) (144 aa) fasta scores: E(): 1.4e-26, 48.6% id in 142 aa. (160 aa) |
| | STY4832 | Similar to Bacteriophage P4 putative P4-specific DNA primase alpha SW:PRIM_BPP4 (P10277) (777 aa) fasta scores: E(): 0, 86.2% id in 774 aa, and to Haemophilus influenzae phage phi-R73 primase-like protein TR:AAF27348 (EMBL:Q9L8P2) (589 aa) fasta scores: E(): 0, 37.5% id in 432 aa. (777 aa) |
| | trpS2 | Similar to Clostridium longisporum tryptophanyl-tRNA synthetase TrpS or TrsA SW:SYW_CLOLO (Q46127) (341 aa) fasta scores: E(): 0, 54.8% id in 330 aa, and to Thermotoga maritima tryptophanyl-tRNA synthetase TrpS SW:SYW_THEMA (Q9WYW2) (328 aa) fasta scores: E(): 0, 36.5% id in 329 aa. Note that the E.coli trpS ortholog is STY4315; Belongs to the class-I aminoacyl-tRNA synthetase family. (337 aa) |
| | mdoB | Putative phosphoglycerol transferase; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa) |
| | dnaT | Primosomal protein I; This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'. (179 aa) |
| | holD | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (145 aa) |
