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| | STY2181 | Flagellar FliJ protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. (147 aa) |
| | STY2182 | Similar to Salmonella typhimurium flagellar hook-length control protein fliK or FlaE or flaR SW:FLIK_SALTY (P26416) (405 aa) fasta scores: E(): 0, 97.3% id in 409 aa; Orthologue of E. coli fliK (FLIK_ECOLI); Fasta hit to FLIK_ECOLI (375 aa), 49% identity in 414 aa overlap. (409 aa) |
| | STY2186 | Flagellar protein FliO; Identical to Salmonella typhimurium flagellar protein FliO fliO or flbD or flaP SW:FLIO_SALTY (P54699) (125 aa) fasta scores: E(): 0, 100.0% id in 125 aa. Contains hydrophobic, probable membrane-spanning region; Orthologue of E. coli fliO (FLIO_ECOLI); Fasta hit to FLIO_ECOLI (101 aa), 71% identity in 104 aa overlap. (125 aa) |
| | STY2187 | Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (245 aa) |
| | STY2188 | Flagellar biosynthetic protein FliQ; Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family. (89 aa) |
| | STY2189 | Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (264 aa) |
| | stcC | Similar to many e.g. Escherichia coli outer membrane usher protein HtrE precursor htrE SW:HTRE_ECOLI (P33129) (865 aa) fasta scores: E(): 0, 33.0% id in 854 aa. Contains probable N-terminbal signal sequence; Fasta hit to YCBS_ECOLI (866 aa), 31% identity in 804 aa overlap; Fasta hit to FIMD_ECOLI (878 aa), 31% identity in 835 aa overlap; Fasta hit to HTRE_ECOLI (865 aa), 33% identity in 855 aa overlap; Fasta hit to SFMD_ECOLI (867 aa), 31% identity in 828 aa overlap; Orthologue of E. coli yehB (YEHB_ECOLI); Fasta hit to YEHB_ECOLI (826 aa), 75% identity in 829 aa overlap. (829 aa) |
| | stcB | Similar to many e.g. Klebsiella pneumoniae chaperone protein MrkB precursor mrkB SW:MRKB_KLEPN (P21646) (233 aa) fasta scores: E(): 6.1e-26, 35.7% id in 235 aa and Bordetella pertussis chaperone protein precursor fimB or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 8.7e-23, 33.8% id in 231 aa; Fasta hit to YRAI_ECOLI (231 aa), 30% identity in 220 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 33% identity in 216 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 35% identity in 222 aa overlap; Orthologue of E. coli yehC (YEHC_ECOLI); Fasta hit to YEHC_ECOLI (239 aa), 64% identity [...] (227 aa) |
| | STY2383 | Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa) |
| | STY2389 | Putative two-component system sensor kinase; Orthologue of E. coli yehU (YEHU_ECOLI); Fasta hit to YEHU_ECOLI (561 aa), 92% identity in 561 aa overlap. (561 aa) |
| | STY2449 | Putative membrane protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (239 aa) |
| | dsbE1 | Thiol:disulfide interchange protein; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily. (185 aa) |
| | ccmF1 | Cytochrome c-type biogenesis protein F1; Fasta hit to NRFE_ECOLI (552 aa), 38% identity in 611 aa overlap; Orthologue of E. coli ccmF (CCMF_ECOLI); Fasta hit to CCMF_ECOLI (647 aa), 85% identity in 646 aa overlap. (643 aa) |
| | ccmE1 | Cytochrome c-type biogenesis protein E1; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (159 aa) |
| | ccmD1 | Heme exporter protein D1; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (70 aa) |
| | ccmC1 | Heme exporter protein C1; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (245 aa) |
| | ccmB1 | Heme exporter protein B1; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (219 aa) |
| | ccmA1 | Heme exporter protein A1; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa) |
| | STY2499 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (878 aa) |
| | STY2664 | Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (328 aa) |
| | STY2726 | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (344 aa) |
| | STY2765 | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (392 aa) |
| | STY2783 | Conserved hypothetical protein; Orthologue of E. coli yfhJ (YFHJ_ECOLI); Fasta hit to YFHJ_ECOLI (66 aa), 92% identity in 66 aa overlap. (66 aa) |
| | STY2785 | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. (616 aa) |
| | STY2786 | Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (171 aa) |
| | STY2787 | Conserved hypothetical protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. (107 aa) |
| | nifU | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa) |
| | STY2789 | Putative L-cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate; Belongs to the class-V pyridoxal-phosphate-dependent am [...] (404 aa) |
| | STY2813 | Putative exported protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (475 aa) |
| | STY2836 | ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (444 aa) |
| | STY2852 | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (245 aa) |
| | corE | Putative membrane protein; Similar to Salmonella typhimurium CorE corE TR:Q9X619 (EMBL:AF130857) (288 aa) fasta scores: E(): 0, 98.5% id in 263 aa. Shares a region of similarity with e.g. Chlamydomonas reinhardtii cytochrome C biogenesis protein CcsA ccsA SW:CCSA_CHLRE (P48269) (353 aa) fasta scores: E(): 2.4e-05, 24.2% id in 207 aa. Contains hydrophobic, probable membrane-spanning regions; Orthologue of E. coli P76599; Fasta hit to P76599 (288 aa), 94% identity in 263 aa overlap. (263 aa) |
| | STY2871 | Small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (112 aa) |
| | STY3065 | Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (305 aa) |
| | STY3067 | Hypothetical protein; Similar to the N-terminus of Escherichia coli orf_f226 TR:Q46898 (EMBL:U29579) (226 aa) fasta scores: E(): 2.6e-16, 41.4% id in 169 aa. (241 aa) |
| | steB | Similar to Salmonella typhimurium outer membrane usher protein StfC TR:O87658 (EMBL:AF093503) (885 aa) fasta scores: E(): 0, 53.3% id in 891 aa. Contains a possible N-terminal signal sequence. (899 aa) |
| | steC | Similar to Salmonella typhimurium periplasmic fimbrial chaperone StfD TR:O87659 (EMBL:AF093503) (250 aa) fasta scores: E(): 0, 52.4% id in 250 aa and to Escherichia coli hypothetical fimbrial chaperone SW:YFCS_ECOLI (250 aa) fasta scores: E(): 0, 52.1% id in 238 aa; Orthologue of E. coli YFCS_ECOLI; Fasta hit to YFCS_ECOLI (250 aa), 52% identity in 238 aa overlap. (257 aa) |
| | STY3124 | Similar to many NifS-like aminotransferases e.g. Synechocystis sp NifS TR:Q55793 (EMBL:D64004) (420 aa) fasta scores: E(): 0, 40.4% id in 403 aa; Fasta hit to P77444 (406 aa), 44% identity in 404 aa overlap; Orthologue of E. coli Q46925; Fasta hit to Q46925 (401 aa), 89% identity in 401 aa overlap. (401 aa) |
| | STY3128 | Membrane-bound lytic murein transglycosylase A precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (365 aa) |
| | recD | Exonuclease V alpha-subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Hol [...] (611 aa) |
| | recB | Exonuclease V subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzym [...] (1181 aa) |
| | recC | Exonuclease V subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzym [...] (1123 aa) |
| | stdC | Weakly similar to Escherichia coli chaperone protein PapD involved in pili assembly SW:PAPD_ECOLI (P15319) (239 aa) fasta scores: E(): 5.9e-33, 37.8% id in 238 aa; Paralogue of E. coli YBGP_ECOLI; Fasta hit to YBGP_ECOLI (242 aa), 40% identity in 222 aa overlap. (247 aa) |
| | stdB | Similar to Escherichia coli hypothetical outer membrane usher protein YqiG SW:YQIG_ECOLI (P76655) (821 aa) fasta scores: E(): 0, 42.2% id in 812 aa. (829 aa) |
| | STY3197 | Peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (365 aa) |
| | STY3216 | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa) |
| | mltC | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (361 aa) |
| | STY3351 | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (752 aa) |
| | STY3359 | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (630 aa) |
| | STY3384 | Bacitracin resistance protein (putative undecaprenol kinase); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (273 aa) |
| | STY3461 | ATP-dependent RNA helicase (dead-box protein); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (646 aa) |
| | STY3486 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | STY3496 | Possible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa) |
| | STY3497 | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (172 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (242 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (156 aa) |
| | recQ | Similar to Escherichia coli ATP-dependent DNA helicase RecQ SW:RECQ_ECOLI (P15043; P76762) (607 aa) fasta scores: E(): 0, 94.6% id in 608 aa. (609 aa) |
| | STY3608 | DNA helicase II; Fasta hit to REP_ECOLI (673 aa), 38% identity in 666 aa overlap; Orthologue of E. coli uvrD (UVRD_ECOLI); Fasta hit to UVRD_ECOLI (720 aa), 98% identity in 720 aa overlap. (720 aa) |
| | STY3616 | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (106 aa) |
| | STY3637 | Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (367 aa) |
| | STY3642 | ATP-dependent DNA helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (674 aa) |
| | cI | Repressor protein; Similar to Bacteriophage 186 repressor protein cI SW:RPC1_BP186 (P08707) (192 aa) fasta scores: E(): 2.6e-19, 32.0% id in 175 aa. (189 aa) |
| | STY3715 | Histone like DNA-binding protein HU-alpha (NS2) (HU-2); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. (90 aa) |
| | STY3742 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (342 aa) |
| | STY3743 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (260 aa) |
| | STY3775 | Primosomal protein replication factor; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa) |
| | STY3777 | Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (330 aa) |
| | STY3782 | Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (79 aa) |
| | STY3871 | GTP-binding protein; Similar to Escherichia coli GTP-binding protein implicated in virulence in EPEC strains, TypA SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 0, 97.0% id in 591 aa. (607 aa) |
| | STY3880 | ATP/GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (210 aa) |
| | STY3916 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (456 aa) |
| | stgB | Similar to Escherichia coli chaperone protein precursor FocC SW:FOCC_ECOLI (P46008) (227 aa) fasta scores: E(): 1.1e-24, 34.9% id in 215 aa; Fasta hit to YRAI_ECOLI (231 aa), 38% identity in 219 aa overlap; Fasta hit to YBGP_ECOLI (242 aa), 34% identity in 224 aa overlap; Fasta hit to YEHC_ECOLI (239 aa), 32% identity in 226 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 34% identity in 231 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 35% identity in 226 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 36% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 34% identity in 215 a [...] (232 aa) |
| | STY3943 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (804 aa) |
| | STY3957 | TorD protein; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily. (210 aa) |
| | ccmA2 | Similar to Escherichia coli heme exporter protein A SW:CCMA_ECOLI () (205 aa) fasta scores: E(): 0, 79.5% id in 200 aa; Fasta hit to YBBA_ECOLI (228 aa), 32% identity in 203 aa overlap; Fasta hit to BTUD_ECOLI (249 aa), 31% identity in 206 aa overlap. (205 aa) |
| | ccmB2 | Similar to Escherichia coli heme exporter protein B CcmB SW:CCMB_ECOLI (P33930) (220 aa) fasta scores: E(): 0, 86.2% id in 217 aa. (218 aa) |
| | ccmC2 | Heme exporter protein C2; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (248 aa) |
| | ccmD2 | Heme exporter protein D2; Orthologue of E. coli ccmD (CCMD_ECOLI); Fasta hit to CCMD_ECOLI (69 aa), 77% identity in 70 aa overlap. (70 aa) |
| | ccmE2 | Cytochrome c-type biogenesis protein E2; Orthologue of E. coli ccmE (CCME_ECOLI); Fasta hit to CCME_ECOLI (159 aa), 84% identity in 159 aa overlap. (159 aa) |
| | ccmF2 | Similar to Escherichia coli cytochrome c-type biogenesis protein CcmF SW:CCMF_ECOLI (P33927) (647 aa) fasta scores: E(): 0, 85.1% id in 646 aa; Fasta hit to NRFE_ECOLI (552 aa), 38% identity in 611 aa overlap. (643 aa) |
| | dsbE2 | Similar to Escherichia coli thiol:disulfide interchange protein DsbE or CcmG precursor SW:DSBE_ECOLI (P33926) (185 aa) fasta scores: E(): 0, 85.9% id in 185 aa. (185 aa) |
| | STY4048 | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | secB | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (155 aa) |
| | STY4285 | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa) |
| | yrdD | Conserved hypothetical protein; Orthologue of E. coli yrdD (YRDD_ECOLI); Fasta hit to YRDD_ECOLI (169 aa), 80% identity in 167 aa overlap. It also shows some smilarity to the C-terminus of some bacterial topoisomerase I. (180 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. (471 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis (By similarity). (359 aa) |
| | STY4479 | Similar to Escherichia coli cytochrome c-type biogenesis protein CcmF SW:CCMF_ECOLI (P33927) (647 aa) fasta scores: E(): 0, 38.3% id in 637 aa, and to Pseudomonas fluorescens inner membrane or periplasmic protein PFCYT4 TR:Q51753 (EMBL:Z47979) (714 aa) fasta scores: E(): 0, 36.0% id in 702 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (578 aa) |
| | STY4522 | DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (454 aa) |
| | topB | Topoisomerase B; Previously sequenced Salmonella typhi topoisomerase B TopB TR:Q9RHF5 (EMBL:AF000001) (664 aa) fasta scores: E(): 0, 100.0% id in 664 aa. Also similar to Escherichia coli DNA topoisomerase III TopB SW:TOP3_ECOLI (P14294) (653 aa) fasta scores: E(): 0, 40.7% id in 619 aa. (664 aa) |
| | sopE | Invasion-associated secreted protein; Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non- phagocytic cells (By similarity). (240 aa) |
| | cI-2 | Similar to Bacteriophage 186 repressor protein cI SW:RPC1_BP186 (P08707) (192 aa) fasta scores: E(): 6.2e-07, 32.1% id in 193 aa. Also similar to Escherichia coli hypothetical protein SW:YR7I_ECOLI (P21323) (198 aa) fasta scores: E(): 6.6e-16, 41.2% id in 199 aa. Contains helix-turn-helix motif, residues 26 to 47, score 975 (+2.51 SD). (210 aa) |
| | tviE | Vi polysaccharide biosynthesis protein TviE, Glycosyl transferases group 1; Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipC or TviE SW:VIPC_SALTI (Q04975) (578 aa) fasta scores: E(): 0, 99.5% id in 578 aa. (578 aa) |
| | tviD | Vi polysaccharide biosynthesis protein; May be required for maturation of the Vi polysaccharide. (831 aa) |
| | tviC | Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipB or TviC SW:VIPB_SALTI (Q04973) (348 aa) fasta scores: E(): 0, 100.0% id in 348 aa, and to Pseudomonas aeruginosa WbpP TR:Q9RHD6 (EMBL:AF035937) (341 aa) fasta scores: E(): 0, 66.6% id in 338 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa) |
| | tviB | Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipA or TviB SW:VIPA_SALTI (Q04972) (425 aa) fasta scores: E(): 0, 99.8% id in 425 aa, and to Pseudomonas aeruginosa WbpO TR:Q9RHD7 (EMBL:AF035937) (422 aa) fasta scores: E(): 0, 66.8% id in 422 aa; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (425 aa) |
| | tviA | Similar to Salmonella typhi Vi polysaccharide biosynthesis protein TviA SW:TVIA_SALTI (Q04971) (179 aa) fasta scores: E(): 0, 100.0% id in 179 aa and to Salmonella paratyphi C VipR protein TR:BAA24231 (EMBL:AB006131) (179 aa) fasta scores: E(): 0, 100.0% id in 179 aa. (179 aa) |
| | STY4664 | Putative DNA helicase; Similar to Escherichia coli helicase IV HelD SW:HELD_ECOLI (P15038) (684 aa) fasta scores: E(): 0.067, 27.5% id in 320 aa and to Salmonella typhi putative DNA helicase TrhI TR:AAF69842 (EMBL:UNNKOWN ACCESSION) (594 aa) fasta scores: E(): 0.24, 19.4% id in 454 aa. (503 aa) |
| | dsbD | Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (567 aa) |
| | mpl | Murein peptide ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (457 aa) |
| | STY4801 | Putative transcriptional regulator; Regulates arginine biosynthesis genes. (162 aa) |
| | sefB | Similar to Salmonella enteritidis chaperone protein SefB precursor SW:SEFB_SALEN (P33387) (246 aa) fasta scores: E(): 0, 99.2% id in 246 aa, and to Yersinia pestis, and Yersinia pseudotuberculosis chaperone protein PsaB precursor SW:PSAB_YERPE (P31523) (273 aa) fasta scores: E(): 4e-25, 33.5% id in 257 aa, and to Escherichia coli chaperone protein AggD precursor SW:AGGD_ECOLI (P46004) (252 aa) fasta scores: E(): 2.1e-23, 33.5% id in 209 aa. CDS DNA has a low GC content, 28.81%. (250 aa) |
| | sefC | Similar to Salmonella enteritidis outer membrane usher protein SefC precursor SW:SEFC_SALEN (P33388) (814 aa) fasta scores: E(): 0, 96.7% id in 838 aa, and to Salmonella typhimurium outer membrane usher protein FimD precursor fimD SW:FIMD_SALTY (P37924) (870 aa) fasta scores: E(): 0, 31.0% id in 836 aa. Identity with SefC is distrupted with Glycine-Valine repeat between codons 301 and 330. TTGGTG repeated 14 times. Possible effect on function. CDS DNA has a low GC content,35.71%. (838 aa) |
| | STY4910 | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | slt | Similar to Escherichia coli soluble lytic murein transglycosylase precursor slt or sltY SW:SLT_ECOLI (P03810; P76820) (645 aa) fasta scores: E(): 0, 91.2% id in 627 aa. (627 aa) |
| | sthB | Similar to Escherichia coli chaperone protein FimC SW:FIMC_ECOLI (P31697; P71220) (241 aa) fasta scores: E(): 6.3e-23, 32.6% id in 218 aa, and to Proteus mirabilis type 1 fimbrial chaperone AtfB TR:P72210 (EMBL:Z78535) (225 aa) fasta scores: E(): 7.1e-24, 33.0% id in 221 aa, and to Salmonella typhi FinC gene finC TR:Q56085 (EMBL:X74602) (237 aa) fasta scores: E(): 5.3e-23, 33.0% id in 215 aa. (227 aa) |
| | STY1092 | Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (169 aa) |
| | STY1097 | Helicase IV (75 kD helicase); Orthologue of E. coli helD (HELD_ECOLI); Fasta hit to HELD_ECOLI (684 aa), 84% identity in 684 aa overlap. (684 aa) |
| | scsB | Similar to Salmonella typhimurium suppressor for copper-sensitivity B precursor ScsB TR:O33918 (EMBL:U75949) fasta scores: E(): 0, 95.4% id in 628 aa. (628 aa) |
| | mviN | Virulence factor MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (497 aa) |
| | STY1210 | Flagella synthesis protein FlgN; Required for the efficient initiation of filament assembly. Belongs to the FlgN family. (140 aa) |
| | STY1211 | Negative regulator of flagellin synthesis (anti-sigma factor); Orthologue of E. coli flgM (FLGM_ECOLI); Fasta hit to FLGM_ECOLI (97 aa), 80% identity in 96 aa overlap. (97 aa) |
| | STY1212 | Flagellar basal body P-ring protein FlgA precursor; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (219 aa) |
| | STY1215 | Flagellar hook formation protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein (By similarity). (232 aa) |
| | STY1221 | Flagellar protein FlgJ; Orthologue of E. coli flgJ (FLGJ_ECOLI); Fasta hit to FLGJ_ECOLI (313 aa), 83% identity in 316 aa overlap. (316 aa) |
| | STY1222 | Flagellar hook-associated protein 1; Orthologue of E. coli flgK (FLGK_ECOLI); Fasta hit to FLGK_ECOLI (546 aa), 80% identity in 554 aa overlap. (553 aa) |
| | STY1238 | Putative secreted protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (338 aa) |
| | STY1249 | Putative glycosyl hydrolase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (341 aa) |
| | STY1256 | Transcription-repair coupling factor (TrcF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1148 aa) |
| | STY1290 | Respiratory nitrate reductase 1 delta chain; Fasta hit to NARW_ECOLI (231 aa), 55% identity in 233 aa overlap; Orthologue of E. coli narJ (NARJ_ECOLI); Fasta hit to NARJ_ECOLI (236 aa), 88% identity in 236 aa overlap. (236 aa) |
| | STY1336 | DNA topoisomerase I, omega protein I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus [...] (865 aa) |
| | STY1383 | Conserved hypothetical protein; Orthologue of E. coli YCJI_ECOLI; Fasta hit to YCJI_ECOLI (262 aa), 91% identity in 242 aa overlap. (242 aa) |
| | pcgL | D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (256 aa) |
| | STY1486 | Respiratory nitrate reductase 2 delta chain; Fasta hit to NARJ_ECOLI (236 aa), 58% identity in 233 aa overlap; Orthologue of E. coli narW (NARW_ECOLI); Fasta hit to NARW_ECOLI (231 aa), 82% identity in 231 aa overlap. (231 aa) |
| | STY1745 | Major outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane; Belongs to the Lpp family. (78 aa) |
| | lppB | Major outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane; Belongs to the Lpp family. (79 aa) |
| | STY1749 | Conserved hypothetical protein; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family. (138 aa) |
| | STY1751 | Similar to Escherichia coli hypothetical 46.8 kDa protein in lpp-arod intergenic region ynhC SW:YNHC_ECOLI (P77689) (423 aa) fasta scores: E(): 0, 78.4% id in 421 aa, and to Synechocystis sp hypothetical 50.0 kDa protein Slr0076 slr0076 SW:Y076_SYNY3 (Q55792) (453 aa) fasta scores: E(): 4e-22, 28.4% id in 401 aa; Orthologue of E. coli YNHC_ECOLI; Fasta hit to YNHC_ECOLI (423 aa), 78% identity in 421 aa overlap. (423 aa) |
| | STY1753 | Conserved hypothetical protein; Orthologue of E. coli YNHE_ECOLI; Fasta hit to YNHE_ECOLI (495 aa), 96% identity in 495 aa overlap. (495 aa) |
| | STY1754 | Conserved hypothetical protein; Similar to Azotobacter vinelandii IscA iscA TR:O31271 (EMBL:AF010139) (107 aa) fasta scores: E(): 2.4e-17, 48.1% id in 106 aa; Fasta hit to YADR_ECOLI (114 aa), 33% identity in 107 aa overlap; Fasta hit to YFHF_ECOLI (107 aa), 47% identity in 105 aa overlap; Orthologue of E. coli YDIC_ECOLI; Fasta hit to YDIC_ECOLI (122 aa), 86% identity in 122 aa overlap; Belongs to the HesB/IscA family. (122 aa) |
| | STY1775 | 50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). (118 aa) |
| | STY1816 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] (649 aa) |
| | prfA | Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | mltE | Membrane-bound lytic murein transglycosylase E; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain. (203 aa) |
| | STY1929 | Putative Na+/H+ exchanger; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily. (577 aa) |
| | STY1944 | Septum site determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (235 aa) |
| | ftsI2 | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa) |
| | STY2102 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa) |
| | ruvA | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa) |
| | STY2121 | Flagellar protein FlhE precursor; Not essential for flagellar formation and function. (130 aa) |
| | STY2122 | Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (692 aa) |
| | STY2180 | Similar to Salmonella typhimurium flagellum-specific ATP synthase fliI or flaC SW:FLII_SALTY (P26465) (456 aa) fasta scores: E(): 0, 99.6% id in 456 aa; Fasta hit to ATPB_ECOLI (459 aa), 30% identity in 416 aa overlap; Orthologue of E. coli fliI (FLII_ECOLI); Fasta hit to FLII_ECOLI (457 aa), 93% identity in 456 aa overlap. (456 aa) |
| | flhB | Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (383 aa) |
| | STY2133 | Flagellar transcriptional activator; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (194 aa) |
| | STY2134 | Flagellar transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (116 aa) |
| | fliS | Flagellar protein FliS; Similar to Salmonella typhimurium flagellar protein FliS fliS SW:FLIS_SALTY (P26609) (135 aa) fasta scores: E(): 0, 99.3% id in 135 aa; Orthologue of E. coli fliS (FLIS_ECOLI); Fasta hit to FLIS_ECOLI (136 aa), 62% identity in 129 aa overlap. (135 aa) |
| | fliT | Flagellar protein FliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (122 aa) |
| | STY2179 | Similar to Salmonella typhimurium flagellar assembly protein FliH fliH SW:FLIH_SALTY (P15934) (235 aa) fasta scores: E(): 0, 99.6% id in 235 aa; Orthologue of E. coli fliH (FLIH_ECOLI); Fasta hit to FLIH_ECOLI (228 aa), 82% identity in 235 aa overlap. (235 aa) |
| | bcfB | Fimbrial chaperone; Similar to Salmonella typhimurium fimbrial chaperone BCFB TR:Q9X605 (EMBL:AF130422) fasta scores: E(): 0, 98.7% id in 228 aa, and to Salmonella typhimurium chaperone protein fimc precursor FIMC SW:FIMC_SALTY (P37923) fasta scores: E(): 0, 49.5% id in 220 aa; Fasta hit to YCBR_ECOLI (233 aa), 45% identity in 231 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 35% identity in 225 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 46% identity in 237 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 33% identity in 225 aa overlap; Fasta hit to YCBF_ECOLI (245 aa), 33% identity in [...] (228 aa) |
| | bcfG | Fimbrial chaperone; Similar to Salmonella typhimurium fimbrial chaperone BCFG TR:Q9X609 (EMBL:AF130422) fasta scores: E(): 0, 96.9% id in 229 aa, and to Escherichia coli hypothetical fimbrial chaperone in pepn-pyrd intergenic region precursor YCBF SW:YCBF_ECOLI (P40876; P75861) fasta scores: E(): 0, 41.9% id in 234 aa; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 223 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 32% identity in 216 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 33% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 36% identity in 223 aa overlap; Fasta h [...] (234 aa) |
| | STY0107 | Survival protein SurA precursor; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (428 aa) |
| | STY0108 | Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Belongs to the LptD family. (784 aa) |
| | STY0111 | Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa) |
| | STY0142 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (588 aa) |
| | STY0143 | UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopim ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa) |
| | STY0144 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diami nopimelate--D-alan alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (452 aa) |
| | STY0145 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | STY0146 | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (438 aa) |
| | STY0147 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (414 aa) |
| | STY0148 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa) |
| | STY0149 | UDP-N-acetylmuramate:alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (491 aa) |
| | STY0150 | D-alanine:D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa) |
| | STY0151 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (276 aa) |
| | STY0153 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (383 aa) |
| | STY0161 | Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (247 aa) |
| | staC | Outer membrane usher protein HtrE precursor; Fasta hit to YCBS_ECOLI (866 aa), 32% identity in 873 aa overlap; Fasta hit to YRAJ_ECOLI (838 aa), 34% identity in 841 aa overlap; Fasta hit to FIMD_ECOLI (878 aa), 33% identity in 881 aa overlap; Fasta hit to YEHB_ECOLI (826 aa), 32% identity in 833 aa overlap; Fasta hit to SFMD_ECOLI (867 aa), 31% identity in 866 aa overlap; Orthologue of E. coli htrE (HTRE_ECOLI); Fasta hit to HTRE_ECOLI (865 aa), 60% identity in 852 aa overlap. (863 aa) |
| | staB | Chaperone protein EcpD precursor; Fasta hit to YEHC_ECOLI (239 aa), 34% identity in 237 aa overlap; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 233 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 36% identity in 213 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 33% identity in 215 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 33% identity in 234 aa overlap; Fasta hit to YCBF_ECOLI (245 aa), 30% identity in 216 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 31% identity in 239 aa overlap; Fasta hit to YQIH_ECOLI (252 aa), 31% identity in 239 aa overlap; Fasta hit to YBGP_ECOLI (242 a [...] (244 aa) |
| | STY0215 | Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (840 aa) |
| | STY0226 | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. (129 aa) |
| | STY0242 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | STY0244 | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (252 aa) |
| | yaeT | Outer membrane protein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (803 aa) |
| | STY0265 | Putative release factor; Similar to Escherichia coli hypothetical 15.6 kDa protein in mesj-cutf intergenic region yaeJ SW:YAEJ_ECOLI (P40711) (140 aa) fasta scores: E(): 0, 84.6% id in 136 aa, and to Pseudomonas putida hypothetical 15.2 kDa protein in pcaj 3'region SW:YAEJ_PSEPU (P45388) (137 aa) fasta scores: E(): 9.5e-27, 57.0% id in 135 aa and to Salmonella typhimurium peptide chain release factor 2 prfB SW:RF2_SALTY (P28353) (365 aa) fasta scores: E(): 0.45, 29.6% id in 108 aa; Orthologue of E. coli yaeJ (YAEJ_ECOLI); Fasta hit to YAEJ_ECOLI (140 aa), 85% identity in 136 aa overlap. (140 aa) |
| | mltD | Similar to Escherichia coli membrane-bound lytic murein transglycosylase d precursor mltd or dniR SW:MLTD_ECOLI (P23931; P32982; P77350) (452 aa) fasta scores: E(): 0, 91.4% id in 455 aa, and to Neisseria meningitidis |+++ unknown: ox in cab84739 +++| putative membrane bound murein transglycosylase TR:CAB84739 (EMBL:AL162756) (658 aa) fasta scores: E(): 4.4e-32, 35.2% id in 341 aa, and to Bacteriophage phi-LC3 LysB lysB TR:Q37969 (EMBL:U04309) (429 aa) fasta scores: E(): 3.9e-06, 30.4% id in 161 aa; Orthologue of E. coli dniR (MLTD_ECOLI); Fasta hit to MLTD_ECOLI (452 aa), 91% identity [...] (455 aa) |
| | safB | Similar to Escherichia coli chaperone protein AggD precursor SW:AGGD_ECOLI (P46004) (252 aa) fasta scores: E(): 0, 50.9% id in 216 aa, and to Escherichia coli chaperone protein AfaB precursor afaB SW:AFAB_ECOLI (P53516) (247 aa) fasta scores: E(): 0, 48.9% id in 227 aa; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 203 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 31% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 35% identity in 199 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 30% identity in 198 aa overlap; Paralogue of E. coli yraI (YRAI_ECOLI); Fasta hit to YRAI [...] (246 aa) |
| | safC | Similar to Escherichia coli aggregative adherence fimbria I usher protein AafC TR:Q9X4L5 (EMBL:AF114828) (856 aa) fasta scores: E(): 0, 49.9% id in 844 aa, and to Escherichia coli outer membrane usher protein AfaC precursor afaC SW:AFAC_ECOLI (P53517) (859 aa) fasta scores: E(): 0, 49.9% id in 849 aa; Fasta hit to YCBS_ECOLI (866 aa), 35% identity in 859 aa overlap; Fasta hit to YRAJ_ECOLI (838 aa), 36% identity in 843 aa overlap; Fasta hit to SFMD_ECOLI (867 aa), 35% identity in 846 aa overlap; Paralogue of E. coli fimD (FIMD_ECOLI); Fasta hit to FIMD_ECOLI (878 aa), 36% identity in 8 [...] (836 aa) |
| | tcfA | Putative fimbrial protein; Previously sequenced Salmonella typhi and Salmonella enterica fimbrial subunit proteins TsaA or TcfA TR:Q9XDS4 (EMBL:AB029403) (236 aa) fasta scores: E(): 0, 100.0% id in 236 aa, and to Escherichia coli cs1 fimbrial subunit B precursor CsoB or CooB SW:CSOB_ECOLI (P25731) (238 aa) fasta scores: E(): 5.3e-14, 34.6% id in 205 aa, and to Escherichia coli cfa/i fimbrial subunit A precursor cfaA SW:CFAA_ECOLI (P25732) (206 aa) fasta scores: E(): 1.4e-13, 32.8% id in 189 aa. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryoti [...] (236 aa) |
| | prfH | Similar to Escherichia coli peptide chain release factor homologue prfH SW:RFH_ECOLI (P28369; P77246) (141 aa) fasta scores: E(): 0, 81.9% id in 138 aa, and to Treponema pallidum peptide chain release factor 2 PrfB SW:RF2_TREPA (O83585) (368 aa) fasta scores: E(): 2.8e-12, 33.0% id in 206 aa, and to Haemophilus influenzae peptide chain release factor 2 prfb or hi1212 SW:RF2_HAEIN (P43918) (365 aa) fasta scores: E(): 9.8e-10, 37.2% id in 129 aa. (204 aa) |
| | stbE | Similar to Klebsiella pneumoniae chaperone protein MrkB precursor mrkB SW:MRKB_KLEPN (P21646) (233 aa) fasta scores: E(): 9.3e-21, 32.4% id in 204 aa, and to Bordetella pertussis chaperone protein fimb/fhad precursor fimb or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 1.8e-18, 31.7% id in 221 aa; Fasta hit to YRAI_ECOLI (231 aa), 32% identity in 222 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 32% identity in 213 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 30% identity in 207 aa overlap; Fasta hit to YBGP_ECOLI (242 aa), 31% identity in 229 aa overlap; Paralogue of E. co [...] (252 aa) |
| | stbC | Similar to Escherichia coli outer membrane usher protein FimD precursor fimD SW:FIMD_ECOLI (P30130) (878 aa) fasta scores: E(): 0, 31.7% id in 877 aa, and to Salmonella typhimurium outer membrane usher protein FimD precursor fimD SW:FIMD_SALTY (P37924) (870 aa) fasta scores: E(): 0, 32.7% id in 860 aa; Fasta hit to YCBS_ECOLI (866 aa), 31% identity in 872 aa overlap; Fasta hit to YRAJ_ECOLI (838 aa), 32% identity in 840 aa overlap; Fasta hit to HTRE_ECOLI (865 aa), 31% identity in 853 aa overlap; Fasta hit to SFMD_ECOLI (867 aa), 32% identity in 856 aa overlap; Paralogue of E. coli fim [...] (853 aa) |
| | stbB | Similar to Escherichia coli chaperone protein EcpD precursor ecpD SW:ECPD_ECOLI (P33128) (246 aa) fasta scores: E(): 7.4e-32, 40.3% id in 248 aa, and to Bordetella pertussis chaperone protein fimb/fhad precursor fimb or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 3.2e-24, 38.5% id in 208 aa; Fasta hit to YEHC_ECOLI (239 aa), 39% identity in 258 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 34% identity in 233 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 33% identity in 236 aa overlap; Paralogue of E. coli ecpD (ECPD_ECOLI); Fasta hit to ECPD_ECOLI (246 aa), 40% identity in [...] (253 aa) |
| | STY0412 | D-alanine:D-alanine ligase A; Cell wall formation. (364 aa) |
| | STY0493 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. (90 aa) |
| | fimC | Fimbrial chaperone protein; Similar to Salmonella typhi FimC gene fimC TR:Q56085 (EMBL:X74602) (237 aa) fasta scores: E(): 0, 100.0% id in 237 aa, and to Salmonella typhimurium chaperone protein FimC precursor fimC SW:FIMC_SALTY (P37923) (230 aa) fasta scores: E(): 0, 98.3% id in 230 aa; Fasta hit to YEHC_ECOLI (239 aa), 30% identity in 231 aa overlap; Fasta hit to YCBR_ECOLI (233 aa), 41% identity in 219 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 40% identity in 228 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 34% identity in 242 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 48% i [...] (230 aa) |
| | fimD | Similar to Salmonella typhimurium outer membrane usher protein FimD precursor fimD SW:FIMD_SALTY (P37924) (870 aa) fasta scores: E(): 0, 98.0% id in 870 aa, and to Escherichia coli outer membrane usher protein SfmD precursor sfmD SW:SFMD_ECOLI (P77468) (867 aa) fasta scores: E(): 0, 70.0% id in 853 aa, and to Escherichia coli outer membrane usher protein FimD precursor fimD SW:FIMD_ECOLI (P30130) (878 aa) fasta scores: E(): 0, 47.6% id in 867 aa; Fasta hit to YCBS_ECOLI (866 aa), 48% identity in 869 aa overlap; Fasta hit to YRAJ_ECOLI (838 aa), 38% identity in 848 aa overlap; Fasta hit [...] (870 aa) |
| | STY0688 | D-alanine carboxypeptidase; Fasta hit to DACC_ECOLI (400 aa), 60% identity in 401 aa overlap; Fasta hit to DACD_ECOLI (388 aa), 48% identity in 390 aa overlap; Orthologue of E. coli dacA (DACA_ECOLI); Fasta hit to DACA_ECOLI (403 aa), 95% identity in 403 aa overlap; Belongs to the peptidase S11 family. (403 aa) |
| | STY0689 | Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. (377 aa) |
| | STY0690 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa) |
| | pbpA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (633 aa) |
| | STY0693 | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (105 aa) |
| | STY0698 | Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (196 aa) |
| | STY0796 | Putative exported protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (262 aa) |
| | STY0819 | Similar to Erwinia chrysanthemi pectinesterase b precursor pemB SW:PMEB_ERWCH (Q47474) (433 aa) fasta scores: E(): 0, 44.8% id in 429 aa, and to Escherichia coli hypothetical 46.1 kDa protein in modc-bioa intergenic region precursor. putative lipoprotein ybhc precursor SW:YBHC_ECOLI () (427 aa) fasta scores: E(): 0, 86.7% id in 427 aa. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site; Orthologue of E. coli ybhC (YBHC_ECOLI); Fasta hit to YBHC_ECOLI (427 aa), 87% identity in 427 aa overlap. (427 aa) |
| | STY0855 | Putative ATP-dependent RNA helicase rhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (455 aa) |
| | STY0870 | DNA protection during starvation protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. (167 aa) |
| | STY0896 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6 precursor); Fasta hit to DACD_ECOLI (388 aa), 47% identity in 384 aa overlap; Fasta hit to DACA_ECOLI (403 aa), 61% identity in 397 aa overlap; Orthologue of E. coli dacC (DACC_ECOLI); Fasta hit to DACC_ECOLI (400 aa), 92% identity in 400 aa overlap; Belongs to the peptidase S11 family. (400 aa) |
| | STY0994 | Killing factor KicB; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa) |
| | STY0995 | KicA protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. (225 aa) |
| | mukB | Cell division protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1488 aa) |
| | STY1080 | Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (181 aa) |
