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| | STY0187 | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (264 aa) |
| | STY0181 | Aconitate hydratase 2 (citrate hydro-lyase 2); Orthologue of E. coli acnB (ACO2_ECOLI); Fasta hit to ACO2_ECOLI (865 aa), 96% identity in 865 aa overlap; Belongs to the aconitase/IPM isomerase family. (865 aa) |
| | ilvI | Similar to Escherichia coli acetolactate synthase isozyme iii large subunit ILVI SW:ILVI_ECOLI (P00893; P78045) fasta scores: E(): 0, 92.2% id in 574 aa, and to Buchnera aphidicola acetolactate synthase large subunit ILVI SW:ILVI_BUCAP (O85293) fasta scores: E(): 0, 70.5% id in 572 aa. (574 aa) |
| | STY0130 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | STY0129 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | STY0080 | Carnitine racemase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. (261 aa) |
| | citX2 | Citx protein; Similar to Escherichia coli citx protein CITX SW:CITX_ECOLI (P77563) fasta scores: E(): 1.5e-26, 43.9% id in 164 aa, and to Leuconostoc mesenteroides citg protein CITG SW:CITG_LEUMC (O53080) fasta scores: E(): 1.1e-11, 28.5% id in 179 aa; Paralogue of E. coli CITX_ECOLI; Fasta hit to CITX_ECOLI (183 aa), 44% identity in 164 aa overlap. (183 aa) |
| | citF2 | Similar to Klebsiella pneumoniae citrate lyase alpha chain CITF SW:CILA_KLEPN (P45413) fasta scores: E(): 0, 91.3% id in 505 aa, and to Escherichia coli citrate lyase alpha chain CITF SW:CILA_ECOLI (P75726; P77102) fasta scores: E(): 0, 72.1% id in 480 aa; Paralogue of E. coli CILA_ECOLI; Fasta hit to CILA_ECOLI (510 aa), 72% identity in 480 aa overlap. (506 aa) |
| | citE2 | Similar to Klebsiella pneumoniae citrate lyase beta chain CITE SW:CILB_KLEPN (P17725) fasta scores: E(): 0, 89.6% id in 289 aa, and to Escherichia coli citrate lyase beta chain CITE SW:CILB_ECOLI (P77770; O54335) fasta scores: E(): 0, 63.4% id in 290 aa; Paralogue of E. coli CILB_ECOLI; Fasta hit to CILB_ECOLI (302 aa), 63% identity in 290 aa overlap; Belongs to the HpcH/HpaI aldolase family. (289 aa) |
| | STY0067 | [citrate (PRO-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (347 aa) |
| | oadG | Oxaloacetate decarboxylase gamma chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (79 aa) |
| | oadA | Oxaloacetate decarboxylase alpha chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (591 aa) |
| | oadB | Oxaloacetate decarboxylase beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (433 aa) |
| | STY0004 | Threonine synthase; Orthologue of E. coli thrC (THRC_ECOLI); Fasta hit to THRC_ECOLI (428 aa), 93% identity in 428 aa overlap. (428 aa) |
| | STY0700 | Putative hydrolase N-terminus; Similar to Campylobacter jejuni putative altronate hydrolase N-terminus uxaa' TR:Q9PI27 (EMBL:AL139075) (87 aa) fasta scores: E(): 1.7e-08, 35.9% id in 92 aa, and to N-terminus of Escherichia coli altronate hydrolase SW:UXAA_ECOLI () (495 aa) fasta scores: E(): 7.6e-06, 38.6% id in 83 aa, and Escherichia coli D-galactarate dehydratase gard or b3128 SW:GARD_ECOLI (P39829) (523 aa) fasta scores: E(): 0.001, 35.0% id in 100 aa. (113 aa) |
| | slt | Similar to Escherichia coli soluble lytic murein transglycosylase precursor slt or sltY SW:SLT_ECOLI (P03810; P76820) (645 aa) fasta scores: E(): 0, 91.2% id in 627 aa. (627 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. (265 aa) |
| | STY4786 | Hypothetical protein; No database matches. (246 aa) |
| | STY4785 | Hypothetical protein; No database matches. (372 aa) |
| | sgaH | Putative hexulose-6-phosphate synthase; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization. Belongs to the HPS/KGPDC family. KGPDC subfamily. (216 aa) |
| | yjeF | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] (515 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (322 aa) |
| | aspA | Similar to Escherichia coli Aspartate ammonia-lyase aspA SW:ASPA_ECOLI (P04422) (478 aa) fasta scores: E(): 0, 97.1% id in 478 aa, and to Serratia marcescens Aspartate ammonia-lyase aspA SW:ASPA_SERMA (P33109) (478 aa) fasta scores: E(): 0, 89.7% id in 478 aa. (478 aa) |
| | tviC | Similar to Salmonella typhi Vi polysaccharide biosynthesis protein VipB or TviC SW:VIPB_SALTI (Q04973) (348 aa) fasta scores: E(): 0, 100.0% id in 348 aa, and to Pseudomonas aeruginosa WbpP TR:Q9RHD6 (EMBL:AF035937) (341 aa) fasta scores: E(): 0, 66.6% id in 338 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa) |
| | fumB | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | adi | Arginine decarboxylase; Similar to Escherichia coli biodegradative arginine decarboxylase SW:ADI_ECOLI (P28629) (755 aa) fasta scores: E(): 0, 93.1% id in 755 aa, and to Escherichia coli lysine decarboxylase, constitutive SW:DCLZ_ECOLI (P52095) (713 aa) fasta scores: E(): 0, 36.2% id in 737 aa. (756 aa) |
| | STY4481 | NrfG protein; Similar to Escherichia coli NrfG SW:NRFG_ECOLI (P32712) (198 aa) fasta scores: E(): 0, 70.2% id in 191 aa and to Yersinia enterocolitica YfrE TR:Q56924 (EMBL:X76082) (257 aa) fasta scores: E(): 4.8e-21, 39.0% id in 182 aa. Contains a predicted transmembrane helix. It also shows some similarity to cytochrome c-type biogenesis proteins from several organisms. (206 aa) |
| | STY4479 | Similar to Escherichia coli cytochrome c-type biogenesis protein CcmF SW:CCMF_ECOLI (P33927) (647 aa) fasta scores: E(): 0, 38.3% id in 637 aa, and to Pseudomonas fluorescens inner membrane or periplasmic protein PFCYT4 TR:Q51753 (EMBL:Z47979) (714 aa) fasta scores: E(): 0, 36.0% id in 702 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (578 aa) |
| | STY4429 | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. (165 aa) |
| | STY4402 | Isocitrate lyase; Similar to Escherichia coli isocitrate lyase AceA SW:ACEA_ECOLI (P05313) (434 aa) fasta scores: E(): 0, 95.6% id in 434 aa, and to Vibrio cholerae isocitrate lyase VC0736 TR:Q9KTZ4 (EMBL:AE004159) (437 aa) fasta scores: E(): 0, 79.4% id in 433 aa. (434 aa) |
| | STY4401 | Similar to Escherichia coli malate synthase A AceB SW:MASY_ECOLI (P08997) (533 aa) fasta scores: E(): 0, 90.8% id in 533 aa, and to Myxococcus xanthus malate synthase mls SW:MASY_MYXXA (P95329) (541 aa) fasta scores: E(): 0, 56.2% id in 511 aa. (533 aa) |
| | pabA | Similar to Salmonella typhimurium para-aminobenzoate synthase glutamine amidotransferase component ii pabA SW:PABA_SALTY (P06193) (187 aa) fasta scores: E(): 0, 99.5% id in 187 aa, and to Escherichia coli para-aminobenzoate synthase glutamine amidotransferase component ii pabA SW:PABA_ECOLI (P00903) (187 aa) fasta scores: E(): 0, 85.0% id in 187 aa. (187 aa) |
| | cysG | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (457 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (362 aa) |
| | STY4296 | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa) |
| | STY4121 | Similar to Methylomonas aminofaciens hexulose-6-phosphate synthase hps SW:HUMS_METAM (Q48907) (208 aa) fasta scores: E(): 5.9e-17, 34.6% id in 205 aa; Fasta hit to SGAH_ECOLI (216 aa), 45% identity in 216 aa overlap; Orthologue of E. coli yiaQ (SGBH_ECOLI); Fasta hit to SGBH_ECOLI (220 aa), 90% identity in 220 aa overlap. (220 aa) |
| | STY4068 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (269 aa) |
| | STY4064 | Conserved hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa) |
| | STY4017 | Putative transferase; Weakly similar to Aquifex aeolicus L-seryl-tRNA selA TR:O67140 (EMBL:AE000719) (452 aa) fasta scores: E(): 0.37, 24.6% id in 403 aa, and to Azotobacter vinelandii dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SW:ODO2_AZOVI (P20708) (398 aa) fasta scores: E(): 0.91, 23.2% id in 285 aa. (369 aa) |
| | STY3977 | D-serine dehydratase; Orthologue of E. coli dsdA (SDHD_ECOLI); Fasta hit to SDHD_ECOLI (442 aa), 89% identity in 442 aa overlap. (440 aa) |
| | ccmF2 | Similar to Escherichia coli cytochrome c-type biogenesis protein CcmF SW:CCMF_ECOLI (P33927) (647 aa) fasta scores: E(): 0, 85.1% id in 646 aa; Fasta hit to NRFE_ECOLI (552 aa), 38% identity in 611 aa overlap. (643 aa) |
| | STY3856 | Putative aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family. (292 aa) |
| | STY3792 | Putative aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family. (291 aa) |
| | STY3769 | Cystathionine gamma-synthase; Fasta hit to METC_ECOLI (395 aa), 31% identity in 394 aa overlap; Orthologue of E. coli metB (METB_ECOLI); Fasta hit to METB_ECOLI (386 aa), 96% identity in 386 aa overlap. (386 aa) |
| | STY3758 | Putative transaldolase; Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction; Belongs to the transaldolase family. Type 3A subfamily. (220 aa) |
| | STY3754 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (883 aa) |
| | STY3750 | Argininosuccinate lyase; Orthologue of E. coli argH (ARLY_ECOLI); Fasta hit to ARLY_ECOLI (457 aa), 95% identity in 456 aa overlap. (458 aa) |
| | STY3726 | Thiamine biosynthesis protein; Orthologue of E. coli thiH (THIH_ECOLI); Fasta hit to THIH_ECOLI (377 aa), 90% identity in 375 aa overlap. (377 aa) |
| | STY3721 | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (631 aa) |
| | STY3718 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa) |
| | STY3653 | Dihydroxyacid dehydratase; Similar to Escherichia coli dihydroxy-acid dehydratase SW:ILVD_ECOLI () (605 aa) fasta scores: E(): 0, 93.9% id in 602 aa and to Haemophilus influenzae dihydroxy-acid dehydratase IlvD SW:ILVD_HAEIN (P44851) (612 aa) fasta scores: E(): 0, 76.9% id in 614 aa. Note that the N-terminus of this CDS is more similar to the H. influenzae IlvD; Fasta hit to YAGF_ECOLI (655 aa), 30% identity in 543 aa overlap; Orthologue of E. coli ilvD (ILVD_ECOLI); Fasta hit to ILVD_ECOLI (605 aa), 94% identity in 602 aa overlap; Belongs to the IlvD/Edd family. (616 aa) |
| | STY3652 | Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (514 aa) |
| | STY3633 | UDP-N-acetylglucosamine epimerase (UDP-GlcNAc-2-epimerase); Fasta hit to RBB1_ECOLI (361 aa), 73% identity in 353 aa overlap; Orthologue of E. coli rffG (RFFG_ECOLI); Fasta hit to RFFG_ECOLI (355 aa), 89% identity in 354 aa overlap; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (355 aa) |
| | STY3622 | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | STY3620 | Adenylate cyclase; Orthologue of E. coli cyaA (CYAA_ECOLI); Fasta hit to CYAA_ECOLI (848 aa), 96% identity in 848 aa overlap; Belongs to the adenylyl cyclase class-1 family. (848 aa) |
| | STY3581 | Conserved hypothetical protein; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (492 aa) |
| | STY3577 | Large (alpha) subunit of the fatty acid-oxidizing multienzyme complex; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa) |
| | STY3535 | Tartrate dehydratase; Orthologue of E. coli ttdA (TTDA_ECOLI); Fasta hit to TTDA_ECOLI (303 aa), 54% identity in 294 aa overlap. (299 aa) |
| | STY3534 | Tartrate dehydratase; Orthologue of E. coli ttdB (TTDB_ECOLI); Fasta hit to TTDB_ECOLI (201 aa), 67% identity in 203 aa overlap. (205 aa) |
| | oadG-2 | Oxaloacetate decarboxylase gamma chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (80 aa) |
| | oadA-2 | Similar to Salmonella typhimurium oxaloacetate decarboxylase alpha chain OadA SW:DCOA_SALTY (Q03030) (590 aa) fasta scores: E(): 0, 98.6% id in 590 aa. (591 aa) |
| | oadB-2 | Oxaloacetate decarboxylase beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (433 aa) |
| | STY3520 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. (297 aa) |
| | STY3506 | Conserved hypothetical protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. (217 aa) |
| | STY3435 | Tagatose-bisphosphate aldolase; Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol. (284 aa) |
| | garD | D-galactarate dehydratase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate. (523 aa) |
| | garL | 5-keto-4-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. (256 aa) |
| | STY3427 | Catabolic threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (329 aa) |
| | tdcE | Probable formate acetyltransferase; Fasta hit to PFLB_ECOLI (759 aa), 79% identity in 752 aa overlap; Orthologue of E. coli yhaS (TDCE_ECOLI); Fasta hit to TDCE_ECOLI (746 aa), 93% identity in 741 aa overlap. (764 aa) |
| | tdcG | Similar to Escherichia coli L-serine dehydratase TdcG SW:TDCG_ECOLI () (454 aa) fasta scores: E(): 0, 86.6% id in 454 aa; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) |
| | STY3373 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (217 aa) |
| | STY3333 | Beta-cystathionase; Fasta hit to METB_ECOLI (386 aa), 32% identity in 398 aa overlap; Orthologue of E. coli metC (METC_ECOLI); Fasta hit to METC_ECOLI (395 aa), 87% identity in 395 aa overlap. (395 aa) |
| | STY3306 | D-mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (394 aa) |
| | mltC | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (361 aa) |
| | speA | Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (658 aa) |
| | STY3226 | Fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | STY3157 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | STY3128 | Membrane-bound lytic murein transglycosylase A precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (365 aa) |
| | STY3113 | Fuculose-1-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (215 aa) |
| | STY3110 | L-serine dehydratase 2 (L-serine deaminase 2); Fasta hit to TDCG_ECOLI (454 aa), 73% identity in 454 aa overlap; Fasta hit to SDHL_ECOLI (454 aa), 77% identity in 455 aa overlap; Orthologue of E. coli sdaB (SDHM_ECOLI); Fasta hit to SDHM_ECOLI (455 aa), 94% identity in 455 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa) |
| | ygcY | Similar to Escherichia coli probable glucarate dehydratase 2 ygcY SW:GUD2_ECOLI (Q46915) (446 aa) fasta scores: E(): 0, 95.1% id in 446 aa; Fasta hit to GUD1_ECOLI (446 aa), 65% identity in 448 aa overlap; Orthologue of E. coli GUD2_ECOLI; Fasta hit to GUD2_ECOLI (446 aa), 95% identity in 446 aa overlap. (446 aa) |
| | ygcX | Similar to Escherichia coli probable glucarate dehydratase 1 ygcX SW:GUD1_ECOLI (P76637; Q46914) (446 aa) fasta scores: E(): 0, 96.4% id in 446 aa; Fasta hit to GUD2_ECOLI (446 aa), 64% identity in 449 aa overlap; Orthologue of E. coli GUD1_ECOLI; Fasta hit to GUD1_ECOLI (446 aa), 96% identity in 446 aa overlap. (446 aa) |
| | STY3081 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | STY3080 | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (223 aa) |
| | STY3077 | Highly similar to Escherichia coli putative 6-pyruvoyl tetrahydrobiopterin synthase YgcM SW:PTPS_ECOLI (Q46903) (121 aa) fasta scores: E(): 0, 94.2% id in 120 aa; Orthologue of E. coli PTPS_ECOLI; Fasta hit to PTPS_ECOLI (121 aa), 94% identity in 120 aa overlap. (120 aa) |
| | ygbB | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa) |
| | STY3047 | Conserved hypothetical protein; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. (475 aa) |
| | STY3041 | Possible sugar aldolase; Weakly similar to a number of aldolases e.g. Escherichia coli L-fuculose phosphate aldolase FucA SW:FUCA_ECOLI (P11550) (215 aa) fasta scores: E(): 6.3e-13, 32.0% id in 206 aa; Fasta hit to FUCA_ECOLI (215 aa), 32% identity in 206 aa overlap; Orthologue of E. coli YGBL_ECOLI; Fasta hit to YGBL_ECOLI (212 aa), 86% identity in 211 aa overlap. (212 aa) |
| | STY2981 | Transcriptional activator of the formate hydrogenlyase system; Fasta hit to HYFR_ECOLI (670 aa), 50% identity in 564 aa overlap; Orthologue of E. coli fhlA (FHLA_ECOLI); Fasta hit to FHLA_ECOLI (692 aa), 90% identity in 691 aa overlap. (692 aa) |
| | STY2975 | Formate hydrogenlyase regulatory protein; Orthologue of E. coli hycA (HYCA_ECOLI); Fasta hit to HYCA_ECOLI (153 aa), 89% identity in 152 aa overlap. (153 aa) |
| | STY2974 | Formate hydrogenlyase subunit 2; Fasta hit to YSAA_ECOLI (157 aa), 38% identity in 187 aa overlap; Fasta hit to YGFS_ECOLI (162 aa), 36% identity in 181 aa overlap; Fasta hit to HYFA_ECOLI (205 aa), 51% identity in 186 aa overlap; Fasta hit to HYDN_ECOLI (175 aa), 39% identity in 190 aa overlap; Orthologue of E. coli hycB (HYCB_ECOLI); Fasta hit to HYCB_ECOLI (203 aa), 96% identity in 202 aa overlap. (202 aa) |
| | STY2973 | Formate hydrogenlyase subunit 3; Fasta hit to HYFB_ECOLI (672 aa), 38% identity in 607 aa overlap; Orthologue of E. coli hycC (HYCC_ECOLI); Fasta hit to HYCC_ECOLI (608 aa), 89% identity in 608 aa overlap. (608 aa) |
| | STY2972 | Formate hydrogenlyase subunit 4; Fasta hit to HYFC_ECOLI (315 aa), 54% identity in 301 aa overlap; Orthologue of E. coli hycD (HYCD_ECOLI); Fasta hit to HYCD_ECOLI (307 aa), 91% identity in 307 aa overlap. (307 aa) |
| | STY2971 | Formate hydrogenlyase subunit 5; Fasta hit to HYFG_ECOLI (555 aa), 72% identity in 563 aa overlap; Orthologue of E. coli hycE (HYCE_ECOLI); Fasta hit to HYCE_ECOLI (569 aa), 97% identity in 569 aa overlap. (569 aa) |
| | STY2970 | Formate hydrogenlyase subunit 6; Fasta hit to HYFH_ECOLI (181 aa), 47% identity in 172 aa overlap; Orthologue of E. coli hycF (HYCF_ECOLI); Fasta hit to HYCF_ECOLI (180 aa), 97% identity in 178 aa overlap. (180 aa) |
| | STY2969 | Formate hydrogenlyase subunit 7; Fasta hit to HYFI_ECOLI (252 aa), 62% identity in 250 aa overlap; Orthologue of E. coli hycG (HYCG_ECOLI); Fasta hit to HYCG_ECOLI (255 aa), 97% identity in 255 aa overlap. (255 aa) |
| | STY2968 | Formate hydrogenlyase maturation protein; Fasta hit to P76566 (158 aa), 48% identity in 131 aa overlap; Orthologue of E. coli hycH (HYCH_ECOLI); Fasta hit to HYCH_ECOLI (136 aa), 92% identity in 136 aa overlap. (136 aa) |
| | STY2952 | Membrane-bound lytic transglycosylase B precursor; Orthologue of E. coli mltB (MLTB_ECOLI); Fasta hit to MLTB_ECOLI (361 aa), 92% identity in 361 aa overlap. (359 aa) |
| | luxS | Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa) |
| | STY2854 | Chorismate mutase-P/prephenate dehydratase; Orthologue of E. coli pheA (PHEA_ECOLI); Fasta hit to PHEA_ECOLI (386 aa), 91% identity in 385 aa overlap. (386 aa) |
| | STY2817 | Putative phophosugar binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (297 aa) |
| | STY2813 | Putative exported protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (475 aa) |
| | STY2806 | Similar to Salmonella typhimurium lysine decarboxylase, inducible SW:DCLY_SALTY (Q60002) (715 aa) fasta scores: E(): 0, 97.5% id in 715 aa; Fasta hit to DCOS_ECOLI (732 aa), 33% identity in 623 aa overlap; Fasta hit to ADI_ECOLI (755 aa), 36% identity in 740 aa overlap; Fasta hit to DCLZ_ECOLI (713 aa), 70% identity in 710 aa overlap; Fasta hit to DCOR_ECOLI (731 aa), 34% identity in 616 aa overlap; Orthologue of E. coli cadA (DCLY_ECOLI); Fasta hit to DCLY_ECOLI (715 aa), 92% identity in 714 aa overlap; Belongs to the Orn/Lys/Arg decarboxylase class-I family. (714 aa) |
| | STY2727 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | maeB | NADP-dependent malate dehydrogenase (decarboxylating); Similar to Escherichia coli NADP-dependent malic enzyme maeB SW:MAO2_ECOLI (P76558) (759 aa) fasta scores: E(): 0, 94.3% id in 759 aa; Orthologue of E. coli MAO2_ECOLI; Fasta hit to MAO2_ECOLI (759 aa), 94% identity in 759 aa overlap. (759 aa) |
| | eutA | Similar to Salmonella typhimurium ethanolamine utilization protein EutA eutA SW:EUTA_SALTY (Q9ZFV2) (467 aa) fasta scores: E(): 0, 99.1% id in 467 aa; Orthologue of E. coli EUTA_ECOLI; Fasta hit to EUTA_ECOLI (467 aa), 90% identity in 467 aa overlap. Shares a region of similarity with EutJ and DnaK/FtsA. (467 aa) |
| | eutB | Similar to Salmonella typhimurium ethanolamine ammonia-lyase heavy chain SW:EUTB_SALTY (P19264) (453 aa) fasta scores: E(): 0, 99.8% id in 453 aa; Orthologue of E. coli eutB (EUTB_ECOLI); Fasta hit to EUTB_ECOLI (453 aa), 98% identity in 453 aa overlap. (453 aa) |
| | eutC | Similar to Salmonella typhimurium ethanolamine ammonia-lyase light chain eutC SW:EUTC_SALTY (P19265) (298 aa) fasta scores: E(): 0, 99.3% id in 298 aa; Orthologue of E. coli eutC (EUTC_ECOLI); Fasta hit to EUTC_ECOLI (295 aa), 91% identity in 298 aa overlap; Belongs to the EutC family. (298 aa) |
| | STY2683 | Similar to hypothetical proteins e.g. Neisseria meningitidis serogroup A hypothetical protein NMA0996 TR:Q9JV47 (EMBL:AL162754) (302 aa) fasta scores: E(): 0, 50.3% id in 302 aa, Neisseria meningitidis serogroup B hypothetical protein NMB0786 TR:Q9K036 (EMBL:AE002432) (302 aa) fasta scores: E(): 0, 50.3% id in 302 aa and Vibrio cholerae TyrA protein VC2145 TR:Q9KQ59 (EMBL:AE004287) (302 aa) fasta scores: E(): 0, 45.6% id in 294 aa; Orthologue of E. coli P76536; Fasta hit to P76536 (308 aa), 94% identity in 299 aa overlap. (299 aa) |
| | STY2677 | Cysteine synthase B; Similar to Salmonella typhimurium LT2 cysteine synthase B cysM SW:CYSM_SALTY (P29848) (303 aa) fasta scores: E(): 0, 98.7% id in 303 aa; Fasta hit to CYSK_ECOLI (322 aa), 44% identity in 307 aa overlap; Orthologue of E. coli cysM (CYSM_ECOLI); Fasta hit to CYSM_ECOLI (303 aa), 93% identity in 303 aa overlap; Belongs to the cysteine synthase/cystathionine beta- synthase family. (303 aa) |
| | STY2646 | Putative decarboxylase; Similar to many e.g. Enterobacter cloacae indole-3-pyruvate decarboxylase ipdC SW:DCIP_ENTCL (P23234) (552 aa) fasta scores: E(): 0, 66.7% id in 550 aa and Saccharomyces cerevisiae pyruvate decarboxylase isozyme 3 pdc6 or ygr087C SW:DCP3_YEAST (P26263) (563 aa) fasta scores: E(): 0, 38.1% id in 548 aa. (550 aa) |
| | STY2620 | Putative fatty acid oxidation complex alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa) |
| | STY2616 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | STY2590 | Similar to Bacillus methanolicus diaminopimelate decarboxylase lysA SW:DCDA_BACMT (P41023) (432 aa) fasta scores: E(): 4.8e-21, 28.3% id in 438 aa and to many putative diaminopimelate decarboxylases. (465 aa) |
| | yfbB | Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (252 aa) |
| | menB | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (285 aa) |
| | menC | O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (320 aa) |
| | STY2529 | Putative lipopolysaccharide modification protein; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (660 aa) |
| | STY2521 | Putative MR-MLE-family protein; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR). (405 aa) |
| | STY2519 | Putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 2-keto-3- deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde. Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily. (267 aa) |
| | ccmF1 | Cytochrome c-type biogenesis protein F1; Fasta hit to NRFE_ECOLI (552 aa), 38% identity in 611 aa overlap; Orthologue of E. coli ccmF (CCMF_ECOLI); Fasta hit to CCMF_ECOLI (647 aa), 85% identity in 646 aa overlap. (643 aa) |
| | STY2430 | Putative L-serine dehydratase; Fasta hit to SDHM_ECOLI (455 aa), 50% identity in 452 aa overlap; Fasta hit to TDCG_ECOLI (454 aa), 51% identity in 450 aa overlap; Paralogue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 49% identity in 453 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa) |
| | fbaB | Similar to Escherichia coli fructose-bisphosphate aldolase class I FbaB or DhnA SW:ALF1_ECOLI (P71295) (349 aa) fasta scores: E(): 0, 96.0% id in 349 aa; Orthologue of E. coli ALF1_ECOLI; Fasta hit to ALF1_ECOLI (349 aa), 96% identity in 349 aa overlap. (350 aa) |
| | STY2321 | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa) |
| | STY2307 | dTDP-glucose 4,6-dehydratase; Similar to Salmonella typhimurium strain LT2, group B, dTDP-glucose 4,6-dehydratase rfbB SW:RFBB_SALTY (P26391) (361 aa) fasta scores: E(): 0, 99.4% id in 361 aa; Fasta hit to RFFG_ECOLI (355 aa), 73% identity in 353 aa overlap; Orthologue of E. coli rfbB (RBB1_ECOLI); Fasta hit to RBB1_ECOLI (361 aa), 88% identity in 361 aa overlap; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (361 aa) |
| | rfbG | CDP-glucose 4,6-dehydratase; Similar to Salmonella typhimurium LT2, group B, CDP-glucose 4,6-dehydratase rfbG SW:RFBG_SALTY (P26397) (359 aa) fasta scores: E(): 0, 99.2% id in 359 aa. (359 aa) |
| | STY2286 | Cyclase HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). (258 aa) |
| | STY2284 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity). (196 aa) |
| | STY2283 | Imidazoleglycerol-phosphate dehydratase; Similar to Salmonella typhimurium histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase hisB SW:HIS7_SALTY (P10368) (354 aa) fasta scores: E(): 0, 97.5% id in 355 aa; Orthologue of E. coli hisB (HIS7_ECOLI); Fasta hit to HIS7_ECOLI (355 aa), 96% identity in 355 aa overlap; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (355 aa) |
| | pduC | Similar to Salmonella typhimurium glycerol dehydratase large subunit pduC SW:DHAB_SALTY (P37450) (554 aa) fasta scores: E(): 0, 99.6% id in 554 aa and Klebsiella oxytoca diol dehydratase alpha subunit pddA TR:Q59470 (EMBL:D45071) (554 aa) fasta scores: E(): 0, 99.6% id in 554 aa. (554 aa) |
| | cbiB | CbiB protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate. (319 aa) |
| | STY2161 | Putative deaminase; Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine; Belongs to the ACC deaminase/D-cysteine desulfhydrase family. (328 aa) |
| | STY2093 | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa) |
| | STY1956 | L-serine deaminase 1; Orthologue of E. coli sdaA (SDHL_ECOLI); Fasta hit to SDHL_ECOLI (454 aa), 94% identity in 454 aa overlap; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | mltE | Membrane-bound lytic murein transglycosylase E; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain. (203 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of Lys-170 at the active site; Belongs to the type-I 3-dehydroquinase family. (252 aa) |
| | STY1750 | Putative amintransferase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (406 aa) |
| | ydhZ | Conserved hypothetical protein; In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate; Belongs to the FumD family. (70 aa) |
| | STY1687 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (135 aa) |
| | STY1669 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | fumA | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | STY1653 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa) |
| | STY1494 | NAD-linked malic enzyme; Orthologue of E. coli sfcA (MAO1_ECOLI); Fasta hit to MAO1_ECOLI (574 aa), 92% identity in 572 aa overlap; Belongs to the malic enzymes family. (577 aa) |
| | STY1426 | Hypothetical protein; No significant database matches. (149 aa) |
| | STY1344 | orotidine-5'-P decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (245 aa) |
| | STY1339 | Aconitate hydratase 1 (citrate hydro-lyase 1); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa) |
| | STY1328 | Anthranilate synthase component I; Orthologue of E. coli trpE (TRPE_ECOLI); Fasta hit to TRPE_ECOLI (520 aa), 90% identity in 520 aa overlap. (520 aa) |
| | STY1327 | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (531 aa) |
| | STY1326 | Indole-3-glycerol phosphate synthase; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity). (452 aa) |
| | STY1325 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa) |
| | STY1324 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa) |
| | STY1272 | Adenylosuccinate lyase; Orthologue of E. coli purB (PUR8_ECOLI); Fasta hit to PUR8_ECOLI (456 aa), 94% identity in 456 aa overlap; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | STY1238 | Putative secreted protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (338 aa) |
| | STY1237 | 4-amino-4-deoxychorismate lyase; Orthologue of E. coli pabC (PABC_ECOLI); Fasta hit to PABC_ECOLI (269 aa), 70% identity in 269 aa overlap. (269 aa) |
| | hpcH | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde. (263 aa) |
| | hpcG | Similar to Escherichia coli 2-oxo-hepta-3-ene-1,7-dioic acid hydratase hpcG SW:HPCG_ECOLI (P42270) fasta scores: E(): 0, 90.6% id in 267 aa. (267 aa) |
| | hpaG | Similar to Escherichia coli 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase hpaG SW:HPAG_ECOLI (Q46978) fasta scores: E(): 0, 84.0% id in 430 aa. (429 aa) |
| | STY1098 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (152 aa) |
| | STY1088 | D-3-hydroxydecanoyl-(acyl carrier-protein); Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) |
| | STY0973 | Formate acetyltransferase 1; Fasta hit to TDCE_ECOLI (746 aa), 79% identity in 736 aa overlap; Orthologue of E. coli pflB (PFLB_ECOLI); Fasta hit to PFLB_ECOLI (759 aa), 96% identity in 759 aa overlap. (760 aa) |
| | STY0968 | Pyruvate formate-lyase 1 activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (265 aa) |
| | ybjU | Similar to Escherichia coli L-allo-threonine aldolase ybjU SW:LTAA_ECOLI (P75823) (333 aa) fasta scores: E(): 0, 89.2% id in 333 aa, and to Aeromonas jandaei L-allo-threonine aldolase ltaA SW:LTAA_AERJA (O07051) (338 aa) fasta scores: E(): 0, 53.5% id in 333 aa; Orthologue of E. coli LTAA_ECOLI; Fasta hit to LTAA_ECOLI (333 aa), 89% identity in 333 aa overlap. (333 aa) |
| | ybiY | Similar to Escherichia coli putative pyruvate formate-lyase 3 activating enzyme ybiY SW:PFLE_ECOLI (P75794) (308 aa) fasta scores: E(): 0, 88.0% id in 299 aa, and to Escherichia coli pyruvate formate-lyase 2 activating enzyme pflC SW:PFLC_ECOLI (P32675) (292 aa) fasta scores: E(): 6.6e-19, 35.2% id in 301 aa; Fasta hit to PFLC_ECOLI (292 aa), 35% identity in 301 aa overlap; Orthologue of E. coli PFLE_ECOLI; Fasta hit to PFLE_ECOLI (308 aa), 88% identity in 299 aa overlap. (299 aa) |
| | STY0838 | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa) |
| | STY0836 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | hutH | Similar to Pseudomonas putida histidine ammonia-lyase SW:HUTH_PSEPU (P21310) (509 aa) fasta scores: E(): 0, 77.4% id in 500 aa, and to Rhizobium meliloti histidine ammonia-lyase SW:HUTH_RHIME () (511 aa) fasta scores: E(): 0, 52.6% id in 498 aa; Belongs to the PAL/histidase family. (506 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (561 aa) |
| | STY0771 | Endonuclease VIII, DNA N-glycosylase with an AP lyase activity; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (263 aa) |
| | STY0753 | Conserved hypothetical protein; Orthologue of E. coli YBGK_ECOLI; Fasta hit to YBGK_ECOLI (310 aa), 85% identity in 310 aa overlap. (310 aa) |
| | STY0749 | Deoxyribodipyrimidine photolyase; Orthologue of E. coli phrB (PHR_ECOLI); Fasta hit to PHR_ECOLI (472 aa), 79% identity in 472 aa overlap; Belongs to the DNA photolyase family. (473 aa) |
| | STY0701 | Putative hydrolase C-terminus; Similar to Campylobacter jejuni putative altronate hydrolase c-terminus uxaa' TR:Q9PI26 (EMBL:AL139075) (390 aa) fasta scores: E(): 0, 42.2% id in 389 aa, and to C-terminus of Escherichia coli altronate hydrolase SW:UXAA_ECOLI () (495 aa) fasta scores: E(): 0, 33.4% id in 392 aa, and Escherichia coli D-galactarate dehydratase gard or b3128 SW:GARD_ECOLI (P39829) (523 aa) fasta scores: E(): 0, 33.4% id in 404 aa. (390 aa) |
| | cobD | Putative aminotransferase CobD; Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. (364 aa) |
| | STY0689 | Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides; Belongs to the RlpA family. (377 aa) |
| | citC-2 | [citrate (pro-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (341 aa) |
| | citE | Similar to Escherichia coli citrate lyase beta chain citE SW:CILB_ECOLI (P77770; O54335) (302 aa) fasta scores: E(): 0, 94.7% id in 302 aa, and to Klebsiella pneumoniae citrate lyase beta chain citE SW:CILB_KLEPN (P17725) (289 aa) fasta scores: E(): 0, 63.4% id in 290 aa; Orthologue of E. coli CILB_ECOLI; Fasta hit to CILB_ECOLI (302 aa), 95% identity in 302 aa overlap; Belongs to the HpcH/HpaI aldolase family. (302 aa) |
| | citF | Similar to Escherichia coli citrate lyase alpha chain citF SW:CILA_ECOLI (P75726; P77102) (510 aa) fasta scores: E(): 0, 88.0% id in 510 aa, and to Klebsiella pneumoniae citrate lyase alpha chain citF SW:CILA_KLEPN (P45413) (508 aa) fasta scores: E(): 0, 72.6% id in 468 aa; Orthologue of E. coli CILA_ECOLI; Fasta hit to CILA_ECOLI (510 aa), 88% identity in 510 aa overlap. (509 aa) |
| | STY0666 | Ribonuclease I precursor; Orthologue of E. coli rna (RNI_ECOLI); Fasta hit to RNI_ECOLI (268 aa), 74% identity in 268 aa overlap; Belongs to the RNase T2 family. (268 aa) |
| | STY0582 | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) |
| | STY0581 | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (355 aa) |
| | gcl | Similar to Escherichia coli glyoxylate carboligase SW:GCL_ECOLI () (592 aa) fasta scores: E(): 0, 95.8% id in 592 aa, and to Corynebacterium glutamicum acetolactate synthase large subunit ilvB SW:ILVB_CORGL (P42463) (626 aa) fasta scores: E(): 0, 37.8% id in 561 aa; Belongs to the TPP enzyme family. (593 aa) |
| | STY0541 | Conserved hypothetical protein; Orthologue of E. coli YBAK_ECOLI; Fasta hit to YBAK_ECOLI (159 aa), 91% identity in 159 aa overlap; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | STY0533 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (320 aa) |
| | STY0501 | Putative lyase; Similar to Mycobacterium tuberculosis putative lyase rv3684 or mtv025.032 TR:O69652 (EMBL:AL022121) (346 aa) fasta scores: E(): 0, 61.5% id in 338 aa, and to Cyanidioschyzon merolae O-acetylserine cmoastl2 TR:Q9SSV8 (EMBL:AB031004) (390 aa) fasta scores: E(): 2.3e-16, 27.4% id in 329 aa, and to Emericella nidulans cysteine synthase cysB SW:CYSK_EMENI (P50867) (371 aa) fasta scores: E(): 1.7e-14, 25.6% id in 332 aa. (351 aa) |
| | STY0404 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. (324 aa) |
| | prpD | PrpD protein; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield the cis isomer of 2- methyl-aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate; Belongs to the PrpD family. (483 aa) |
| | prpC | Methylcitrate synthase; Similar to Salmonella typhimurium methylcitrate synthase SW:CISZ_SALTY () (389 aa) fasta scores: E(): 0, 98.7% id in 389 aa, and to Escherichia coli methylcitrate synthase prpC SW:CISZ_ECOLI (P31660; P77217) (389 aa) fasta scores: E(): 0, 96.1% id in 388 aa; Fasta hit to CISY_ECOLI (427 aa), 32% identity in 369 aa overlap; Orthologue of E. coli CISZ_ECOLI; Fasta hit to CISZ_ECOLI (389 aa), 96% identity in 388 aa overlap. (389 aa) |
| | prpB | Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (295 aa) |
| | mltD | Similar to Escherichia coli membrane-bound lytic murein transglycosylase d precursor mltd or dniR SW:MLTD_ECOLI (P23931; P32982; P77350) (452 aa) fasta scores: E(): 0, 91.4% id in 455 aa, and to Neisseria meningitidis |+++ unknown: ox in cab84739 +++| putative membrane bound murein transglycosylase TR:CAB84739 (EMBL:AL162756) (658 aa) fasta scores: E(): 4.4e-32, 35.2% id in 341 aa, and to Bacteriophage phi-LC3 LysB lysB TR:Q37969 (EMBL:U04309) (429 aa) fasta scores: E(): 3.9e-06, 30.4% id in 161 aa; Orthologue of E. coli dniR (MLTD_ECOLI); Fasta hit to MLTD_ECOLI (452 aa), 91% identity [...] (455 aa) |
| | STY0259 | Lysine decarboxylase; Fasta hit to ADI_ECOLI (755 aa), 35% identity in 720 aa overlap; Fasta hit to DCOS_ECOLI (732 aa), 32% identity in 694 aa overlap; Fasta hit to DCOR_ECOLI (731 aa), 35% identity in 626 aa overlap; Fasta hit to DCLY_ECOLI (715 aa), 71% identity in 710 aa overlap; Orthologue of E. coli ldcC (DCLZ_ECOLI); Fasta hit to DCLZ_ECOLI (713 aa), 91% identity in 712 aa overlap. (713 aa) |
| | STY0250 | (3R)-hydroxymyristol acyl carrier protein dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity). (151 aa) |
| | STY0198 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa) |
| | STY0193 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (220 aa) |
