STRINGSTRING
STY2160 STY2160 STY4818 STY4818 STY4817 STY4817 vexB vexB STY4424 STY4424 STY4256 STY4256 STY4224 STY4224 STY4168 STY4168 STY3926 STY3926 STY3793 STY3793 STY3498 STY3498 STY3491 STY3491 sitD sitD sitC sitC STY2937 STY2937 STY2678 STY2678 STY2583 STY2583 STY2582 STY2582 STY2452 STY2452 STY2395 STY2395 cbiQ cbiQ STY2101 STY2101 STY1865 STY1865 STY1571 STY1571 STY1437 STY1437 STY1435 STY1435 STY1384 STY1384 STY1369 STY1369 STY1304 STY1304 STY1266 STY1266 STY0922 STY0922 STY0921 STY0921 STY0911 STY0911 yliB yliB STY0867 STY0867 STY0851 STY0851 STY0850 STY0850 STY0709 STY0709 STY0708 STY0708 phnT phnT STY0195 STY0195
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STY2160Putative ABC transporter membrane protein; Similar to Escherichia coli hypothetical amino-acid ABC transporter permease protein YecS yecS SW:YECS_ECOLI (P76315) (222 aa) fasta scores: E(): 0, 93.2% id in 222 aa, and to Deinococcus radiodurans amino acid ABC transporter, permease protein dr0565 TR:Q9RWV0 (EMBL:AE001914) (226 aa) fasta scores: E(): 0, 50.5% id in 216 aa; Fasta hit to GLTK_ECOLI (224 aa), 38% identity in 212 aa overlap; Fasta hit to ARTQ_ECOLI (238 aa), 34% identity in 236 aa overlap; Fasta hit to ARTM_ECOLI (222 aa), 37% identity in 224 aa overlap; Fasta hit to GLNP_ECOL [...] (222 aa)
STY4818Probable inner membrane protein. Similar to Escherichia coli hypothetical 39.8 kDa protein in pepA-gntV intergenic region YjgQ SW:YJGQ_ECOLI (P39341) (361 aa) fasta scores: E(): 0, 96.9% id in 360 aa, and to Haemophilus influenzae hypothetical protein HI1703 HI1703 SW:YJGQ_HAEIN (P45332) (358 aa) fasta scores: E(): 0, 53.8% id in 353 aa. (360 aa)
STY4817Probable inner membrane protein. Similar to Escherichia coli hypothetical protein YjgP SW:YJGP_ECOLI (P39340) (366 aa) fasta scores: E(): 0, 95.3% id in 359 aa and to Haemophilus influenzae hypothetical protein HI1704 SW:YJGP_HAEIN (P45333) (372 aa) fasta scores: E(): 0, 47.8% id in 358 aa. (366 aa)
vexBVi polysaccharide export inner-membrane protein (ABC-2 type transporter); May form an ATP-driven Vi polysaccharide export apparatus, in association with the VexA, VexC and VexD proteins; Belongs to the ABC-2 integral membrane protein family. (264 aa)
STY4424Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (514 aa)
STY4256sn-Glycerol-3-phosphate transport system permease protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa)
STY4224Similar to Escherichia coli hypothetical ABC transporter ATP-binding protein YhiH SW:YHIH_ECOLI (P37624) (894 aa) fasta scores: E(): 0, 89.3% id in 896 aa, and to Escherichia coli hypothetical ABC transporter ATP-binding protein YbhF SW:YBHF_ECOLI (P75776) (578 aa) fasta scores: E(): 0, 35.9% id in 574 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (913 aa)
STY4168Periplasmic dipeptide transport protein precursor; Fasta hit to SAPA_ECOLI (547 aa), 36% identity in 513 aa overlap; Orthologue of E. coli dppA (DPPA_ECOLI); Fasta hit to DPPA_ECOLI (535 aa), 93% identity in 535 aa overlap. (535 aa)
STY3926Periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
STY3793Putative ABC transport protein, solute-binding component; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity). (340 aa)
STY3498Probable ABC transport protein, ATP-binding component; Fasta hit to ARTP_ECOLI (242 aa), 30% identity in 212 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 30% identity in 203 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 33% identity in 233 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 35% identity in 229 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 31% identity in 237 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 32% identity in 238 aa overlap; Fasta hit to LIVG_ECOLI (255 aa), 32% identity in 249 aa overlap; Fasta hit to FTSE_ECOLI (222 aa), 30% identity in 216 aa overlap; Fasta hit [...] (241 aa)
STY3491Putative membrane protein; Orthologue of E. coli yrbE (YRBE_ECOLI); Fasta hit to YRBE_ECOLI (260 aa), 96% identity in 260 aa overlap. Contains possible membrane spanning hydrophobic domains. (260 aa)
sitDIron transport protein, inner membrane component; Similar to Salmonella typhimurium SitD an iron transport protein located on centisome 63 pathogenicity island TR:Q9XCR9 (EMBL:AF128999) (282 aa) fasta scores: E(): 0, 99.3% id in 282 aa, and to Yersinia pestis chelated iron transport system membrane protein YfeD SW:YFED_YERPE (Q56955) (297 aa) fasta scores: E(): 0, 52.6% id in 266 aa. Contains multiple possible membrane spanning hydrophobic domains. (282 aa)
sitCIron transport protein, inner membrane component; Similar to Salmonella typhimurium SitC an iron transport protein located on centisome 63 pathogenicity island TR:Q9XCS0 (EMBL:AF128999) (286 aa) fasta scores: E(): 0, 99.7% id in 286 aa and to Yersinia pestis chelated iron transport system membrane protein YfeC SW:YFEC_YERPE (Q56954) (294 aa) fasta scores: E(): 0, 66.5% id in 281 aa. Contains multiple possible membrane spanning hydrophobic domains. (286 aa)
STY2937Glycine betaine-binding periplasmic protein precursor; Orthologue of E. coli proX (PROX_ECOLI); Fasta hit to PROX_ECOLI (330 aa), 83% identity in 331 aa overlap. (331 aa)
STY2678Sulphate transport ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (364 aa)
STY2583Histidine transport system permease protein; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity). (228 aa)
STY2582Histidine transport system permease; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity). (235 aa)
STY2452Putative transport system periplasmic binding protein; Orthologue of E. coli yejA (YEJA_ECOLI); Fasta hit to YEJA_ECOLI (604 aa), 86% identity in 601 aa overlap. Contains probable N-terminal signal sequence. (601 aa)
STY2395Putative periplasmic protein; Similar to e.g. Deinococcus radiodurans ABC transporter, periplasmic substrate-binding protein, putative DRA0135 TR:Q9RZ18 (EMBL:AE001862) (369 aa) fasta scores: E(): 0, 51.7% id in 296 aa and Streptomyces coelicolor probable permease binding protein proXL or SCE19A.33 TR:Q9X4J2 (EMBL:AF112365) (322 aa) fasta scores: E(): 1.3e-22, 31.4% id in 287 aa. Contains probable N-terminal signal sequence; Orthologue of E. coli yehZ (YEHZ_ECOLI); Fasta hit to YEHZ_ECOLI (305 aa), 88% identity in 305 aa overlap. (305 aa)
cbiQSimilar to Salmonella typhimurium cobalt transport protein CbiQ cbiQ SW:CBIQ_SALTY (Q05598) (225 aa) fasta scores: E(): 0, 99.1% id in 225 aa. Contains hydrophobic, possible membrane-spanning regions. (225 aa)
STY2101High-affinity zinc uptake system membrane protein; Orthologue of E. coli yebI (ZNUB_ECOLI); Fasta hit to ZNUB_ECOLI (261 aa), 96% identity in 261 aa overlap; Contains hydrophobic, probable membrane-spanning regions. (261 aa)
STY1865Similar to Salmonella typhimurium putative substrate-binding protein oxd-6A TR:O34156 (EMBL:U94729) (528 aa) fasta scores: E(): 0, 98.9% id in 528 aa, and to Escherichia coli hypothetical 36.5 kDa protein in ureR 3'region TR:Q05633 (EMBL:L12007) (336 aa) fasta scores: E(): 0, 63.0% id in 319 aa, and to Streptomyces coelicolor putative substrate binding protein SC9B5.18 TR:Q9ZBG2 (EMBL:AL035206) (542 aa) fasta scores: E(): 6.1e-28, 30.7% id in 515 aa. (544 aa)
STY1571Putative ABC transporter periplasmic binding protein; Similar to Streptomyces coelicolor proxl or sce19a.33 TR:Q9X4J2 (EMBL:AF112365) (322 aa) fasta scores: E(): 1e-32, 39.1% id in 279 aa, and to Bacillus subtilis glycine betaine/carnitine/choline-binding protein precursor opucC SW:OPCC_BACSU (O32243; O31407) (303 aa) fasta scores: E(): 1.4e-14, 30.9% id in 272 aa. (300 aa)
STY1437Putative ABC amino acid transporter permease; Paralogue of E. coli yecC (YECS_ECOLI); Fasta hit to YECS_ECOLI (222 aa), 31% identity in 201 aa overlap. (215 aa)
STY1435Similar to Haemophilus influenzae hypothetical amino-acid ABC transporter permease protein hi0179 hi1079 SW:YA79_HAEIN (P45023) (210 aa) fasta scores: E(): 1.6e-21, 34.8% id in 201 aa; Paralogue of E. coli yecC (YECS_ECOLI); Fasta hit to YECS_ECOLI (222 aa), 35% identity in 208 aa overlap. (226 aa)
STY1384Periplasmic murein peptide-binding protein MppA; Fasta hit to YGIS_ECOLI (535 aa), 43% identity in 527 aa overlap; Fasta hit to OPPA_ECOLI (543 aa), 48% identity in 539 aa overlap; Orthologue of E. coli MPPA_ECOLI; Fasta hit to MPPA_ECOLI (537 aa), 92% identity in 537 aa overlap. (537 aa)
STY1369Peptide transport periplasmic protein SapA precursor; Fasta hit to DPPA_ECOLI (535 aa), 37% identity in 516 aa overlap; Orthologue of E. coli sapA (SAPA_ECOLI); Fasta hit to SAPA_ECOLI (547 aa), 90% identity in 549 aa overlap. (549 aa)
STY1304Periplasmic oligopeptide-binding protein precursor; Fasta hit to YGIS_ECOLI (535 aa), 45% identity in 530 aa overlap; Fasta hit to MPPA_ECOLI (537 aa), 49% identity in 523 aa overlap; Orthologue of E. coli oppA (OPPA_ECOLI); Fasta hit to OPPA_ECOLI (543 aa), 84% identity in 543 aa overlap. (582 aa)
STY1266Spermidine/putrescine transport ATP-binding protein PotA (ABC superfamily); Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
STY0922Arginine transport system permease protein ArtQ; Fasta hit to YECS_ECOLI (222 aa), 32% identity in 240 aa overlap; Fasta hit to HISQ_ECOLI (228 aa), 33% identity in 228 aa overlap; Orthologue of E. coli artQ (ARTQ_ECOLI); Fasta hit to ARTQ_ECOLI (238 aa), 95% identity in 237 aa overlap. (238 aa)
STY0921Arginine transport system permease protein ArtM; Fasta hit to ARTQ_ECOLI (238 aa), 30% identity in 237 aa overlap; Fasta hit to YECS_ECOLI (222 aa), 35% identity in 223 aa overlap; Fasta hit to HISM_ECOLI (238 aa), 35% identity in 211 aa overlap; Orthologue of E. coli artM (ARTM_ECOLI); Fasta hit to ARTM_ECOLI (222 aa), 94% identity in 222 aa overlap. (222 aa)
STY0911Putrescine transport ATP-binding protein PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
yliBPutative ABC transporter periplasmic binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Binds glutathione. (512 aa)
STY0867Glutamine transport system permease protein GlnP; Fasta hit to GLTK_ECOLI (224 aa), 32% identity in 224 aa overlap; Fasta hit to YECS_ECOLI (222 aa), 37% identity in 216 aa overlap; Fasta hit to ARTQ_ECOLI (238 aa), 30% identity in 217 aa overlap; Fasta hit to HISM_ECOLI (238 aa), 31% identity in 206 aa overlap; Orthologue of E. coli glnP (GLNP_ECOLI); Fasta hit to GLNP_ECOLI (219 aa), 96% identity in 219 aa overlap. (219 aa)
STY0851Putative inner membrane protein; Orthologue of E. coli YBHS_ECOLI; Fasta hit to YBHS_ECOLI (377 aa), 94% identity in 372 aa overlap. (376 aa)
STY0850Putative inner membrane protein; Orthologue of E. coli YBHR_ECOLI; Fasta hit to YBHR_ECOLI (368 aa), 95% identity in 368 aa overlap. (368 aa)
STY0709Glutamate/aspartate transport system permease protein GltJ; Fasta hit to YECS_ECOLI (222 aa), 32% identity in 216 aa overlap; Orthologue of E. coli gltJ (GLTJ_ECOLI); Fasta hit to GLTJ_ECOLI (246 aa), 95% identity in 246 aa overlap. (246 aa)
STY0708Glutamate/aspartate transport system permease protein GltK; Fasta hit to YECS_ECOLI (222 aa), 37% identity in 214 aa overlap; Fasta hit to GLNP_ECOLI (219 aa), 32% identity in 224 aa overlap; Orthologue of E. coli gltK (GLTK_ECOLI); Fasta hit to GLTK_ECOLI (224 aa), 96% identity in 223 aa overlap. (224 aa)
phnTProbable ATP-binding component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system (By similarity). (369 aa)
STY0195ABC transporter integral membrane protein; Orthologue of E. coli yadH (YADH_ECOLI); Fasta hit to YADH_ECOLI (256 aa), 94% identity in 256 aa overlap. (256 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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