STRINGSTRING
STY0052 STY0052 STY0239 STY0239 STY0981 STY0981 STY1495 STY1495 STY2853 STY2853 STY2863 STY2863 STY3464 STY3464 STY3524 STY3524 STY4224 STY4224 rpsL rpsL rpsG rpsG rpsC rpsC rpsQ rpsQ rpsN rpsN rpsH rpsH rpsE rpsE rpsM rpsM rpsK rpsK rpsD rpsD rpsF rpsF rpsR rpsR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STY005230S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa)
STY023930S ribosomal protein S2; Orthologue of E. coli rpsB (RS2_ECOLI); Fasta hit to RS2_ECOLI (240 aa), 98% identity in 240 aa overlap; Belongs to the universal ribosomal protein uS2 family. (241 aa)
STY098130S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (557 aa)
STY149530S ribosomal protein S22; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family. (47 aa)
STY2853Putative sigma(54) modulation protein; Fasta hit to RP5M_ECOLI (95 aa), 40% identity in 96 aa overlap; Orthologue of E. coli yfiA (YFIA_ECOLI); Fasta hit to YFIA_ECOLI (112 aa), 92% identity in 111 aa overlap. (112 aa)
STY286330S ribosomal subunit protein S16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity. (82 aa)
STY346430S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
STY352430S ribosomal subunit protein S9; Orthologue of E. coli rpsI (RS9_ECOLI); Fasta hit to RS9_ECOLI (129 aa), 99% identity in 129 aa overlap; Belongs to the universal ribosomal protein uS9 family. (130 aa)
STY4224Similar to Escherichia coli hypothetical ABC transporter ATP-binding protein YhiH SW:YHIH_ECOLI (P37624) (894 aa) fasta scores: E(): 0, 89.3% id in 896 aa, and to Escherichia coli hypothetical ABC transporter ATP-binding protein YbhF SW:YBHF_ECOLI (P75776) (578 aa) fasta scores: E(): 0, 35.9% id in 574 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (913 aa)
rpsL30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa)
rpsG30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsC30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity). Belongs to the universal ribosomal protein uS3 family. (233 aa)
rpsQ30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa)
rpsN30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpsH30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpsE30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (167 aa)
rpsM30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa)
rpsK30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsD30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa)
rpsF30s ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (131 aa)
rpsR30s ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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