STRINGSTRING
yhjJ yhjJ bcfB bcfB bcfG bcfG STY0033 STY0033 STY0040 STY0040 STY0107 STY0107 STY0125 STY0125 STY0127 STY0127 yacK yacK staB staB STY0220 STY0220 btuF btuF STY0231 STY0231 ompH ompH gloB gloB safB safB tcfA tcfA STY0352 STY0352 stbE stbE stbB stbB phnS phnS STY0498 STY0498 STY0542 STY0542 STY0552 STY0552 fimC fimC STY0638 STY0638 dsbG dsbG STY0666 STY0666 STY0688 STY0688 STY0710 STY0710 STY0711 STY0711 STY0729 STY0729 STY0744 STY0744 STY0794 STY0794 STY0796 STY0796 STY0814 STY0814 STY0868 STY0868 ybiS ybiS STY0886 STY0886 yliB yliB yliI yliI STY0896 STY0896 STY0910 STY0910 STY0920 STY0920 STY0923 STY0923 STY0925 STY0925 STY0959 STY0959 STY0998 STY0998 STY1085 STY1085 STY1086 STY1086 scsC scsC STY1153 STY1153 STY1167 STY1167 STY1182 STY1182 STY1187 STY1187 STY1194 STY1194 STY1212 STY1212 STY1221 STY1221 STY1255 STY1255 STY1257 STY1257 STY1262 STY1262 STY1304 STY1304 STY1369 STY1369 STY1375 STY1375 STY1384 STY1384 STY1421 STY1421 STY1438 STY1438 STY1442 STY1442 STY1501 STY1501 STY1522 STY1522 STY1533 STY1533 STY1549 STY1549 STY1571 STY1571 STY1582 STY1582 STY1682 STY1682 ssaJ ssaJ ttrB ttrB STY1805 STY1805 aroQ aroQ STY1858 STY1858 STY1865 STY1865 STY1976 STY1976 STY1980 STY1980 STY2004 STY2004 STY2081 STY2081 STY2099 STY2099 fliY fliY STY2218 STY2218 yohN yohN stcB stcB STY2395 STY2395 STY2396 STY2396 STY2424 STY2424 STY2452 STY2452 STY2482 STY2482 STY2485 STY2485 STY2488 STY2488 rcsC rcsC STY2511 STY2511 STY2584 STY2584 STY2585 STY2585 STY2615 STY2615 pgtC pgtC STY2681 STY2681 STY2687 STY2687 STY2735 STY2735 STY2810 STY2810 STY2831 STY2831 STY2906 STY2906 STY2937 STY2937 STY2940 STY2940 STY2952 STY2952 sitA sitA prgK prgK iap iap STY3078 STY3078 steC steC STY3128 STY3128 STY3129 STY3129 stdC stdC STY3199 STY3199 STY3246 STY3246 STY3259 STY3259 STY3312 STY3312 STY3313 STY3313 STY3320 STY3320 STY3349 STY3349 dsbA dsbA STY3479 STY3479 STY3489 STY3489 STY3496 STY3496 STY3497 STY3497 degQ degQ STY3557 STY3557 STY3713 STY3713 STY3765 STY3765 STY3808 STY3808 STY3811 STY3811 STY3813 STY3813 STY3883 STY3883 STY3894 STY3894 stgB stgB STY3923 STY3923 STY3926 STY3926 STY3952 STY3952 yhjA yhjA STY3967 STY3967 STY4090 STY4090 STY4134 STY4134 bisC bisC STY4168 STY4168 STY4200 STY4200 STY4237 STY4237 STY4248 STY4248 STY4254 STY4254 ggt ggt envZ envZ ppiA ppiA fkpA fkpA STY4420 STY4420 STY4421 STY4421 STY4428 STY4428 aphA aphA STY4475 STY4475 STY4476 STY4476 STY4477 STY4477 phoN phoN artJ artJ cpdB cpdB sefB sefB mdoB mdoB STY4911 STY4911 slt slt sthB sthB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yhjJPutative zinc-protease precursor; Similar to Escherichia coli protein YhjJ precursor yhjJ SW:YHJJ_ECOLI (P37648) (498 aa) fasta scores: E(): 0, 85.7% id in 498 aa, and to Escherichia coli probable zinc protease PqqL pqqL SW:PQQL_ECOLI (P31828) (931 aa) fasta scores: E(): 9.4e-16, 23.2% id in 504 aa; Orthologue of E. coli yhjJ (YHJJ_ECOLI); Fasta hit to YHJJ_ECOLI (498 aa), 86% identity in 498 aa overlap; Belongs to the peptidase M16 family. (495 aa)
bcfBFimbrial chaperone; Similar to Salmonella typhimurium fimbrial chaperone BCFB TR:Q9X605 (EMBL:AF130422) fasta scores: E(): 0, 98.7% id in 228 aa, and to Salmonella typhimurium chaperone protein fimc precursor FIMC SW:FIMC_SALTY (P37923) fasta scores: E(): 0, 49.5% id in 220 aa; Fasta hit to YCBR_ECOLI (233 aa), 45% identity in 231 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 35% identity in 225 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 46% identity in 237 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 33% identity in 225 aa overlap; Fasta hit to YCBF_ECOLI (245 aa), 33% identity in [...] (228 aa)
bcfGFimbrial chaperone; Similar to Salmonella typhimurium fimbrial chaperone BCFG TR:Q9X609 (EMBL:AF130422) fasta scores: E(): 0, 96.9% id in 229 aa, and to Escherichia coli hypothetical fimbrial chaperone in pepn-pyrd intergenic region precursor YCBF SW:YCBF_ECOLI (P40876; P75861) fasta scores: E(): 0, 41.9% id in 234 aa; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 223 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 32% identity in 216 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 33% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 36% identity in 223 aa overlap; Fasta h [...] (234 aa)
STY0033Putative exported protein; Similar to Salmonella typhimurium hypothetical 42.7 kda protein TR:Q9RH97 (EMBL:AF053353) fasta scores: E(): 0, 94.7% id in 281 aa, and to Salmonella typhi putative outer membrane protein R0135 TR:AAF69973 (EMBL:AF250878) fasta scores: E(): 4.2e-23, 30.5% id in 282 aa, and to Coxiella burnetii outer membrane protein precursor COM1 TR:Q57333 (EMBL:Z11828) fasta scores: E(): 4.6e-13, 33.2% id in 274 aa. (281 aa)
STY0040Putative secreted 5'-nucleotidase; Similar to Bacillus subtilis hypothetical 132.7 kda protein in cspb-glpp intergenic region YHCR SW:YHCR_BACSU (P54602) fasta scores: E(): 1.3e-17, 26.4% id in 508 aa, and to Discopyge ommata 5'-nucleotidase precursor SW:5NTD_DISOM (P29240) fasta scores: E(): 2.2e-14, 27.9% id in 559 aa. Contains probable N-terminal signal sequence. (523 aa)
STY0107Survival protein SurA precursor; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (428 aa)
STY0125Thiamine-binding periplasmic protein precursor; Orthologue of E. coli tbpA (TBPA_ECOLI); Fasta hit to TBPA_ECOLI (327 aa), 91% identity in 327 aa overlap. (327 aa)
STY0127Putative ABC transporter periplasmic solute binding protein; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain. (552 aa)
yacKPossible multicopper oxidase precursor; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm (By similarity). (536 aa)
staBChaperone protein EcpD precursor; Fasta hit to YEHC_ECOLI (239 aa), 34% identity in 237 aa overlap; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 233 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 36% identity in 213 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 33% identity in 215 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 33% identity in 234 aa overlap; Fasta hit to YCBF_ECOLI (245 aa), 30% identity in 216 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 31% identity in 239 aa overlap; Fasta hit to YQIH_ECOLI (252 aa), 31% identity in 239 aa overlap; Fasta hit to YBGP_ECOLI (242 a [...] (244 aa)
STY0220Ferrichrome-binding periplasmic protein precursor; Orthologue of E. coli fhuD (FHUD_ECOLI); Fasta hit to FHUD_ECOLI (296 aa), 84% identity in 292 aa overlap. (296 aa)
btuFCobalamin periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa)
STY0231Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. (475 aa)
ompHOuter membrane protein OmpH precursor; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. (161 aa)
gloBProbable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (251 aa)
safBSimilar to Escherichia coli chaperone protein AggD precursor SW:AGGD_ECOLI (P46004) (252 aa) fasta scores: E(): 0, 50.9% id in 216 aa, and to Escherichia coli chaperone protein AfaB precursor afaB SW:AFAB_ECOLI (P53516) (247 aa) fasta scores: E(): 0, 48.9% id in 227 aa; Fasta hit to YCBR_ECOLI (233 aa), 33% identity in 203 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 31% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 35% identity in 199 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 30% identity in 198 aa overlap; Paralogue of E. coli yraI (YRAI_ECOLI); Fasta hit to YRAI [...] (246 aa)
tcfAPutative fimbrial protein; Previously sequenced Salmonella typhi and Salmonella enterica fimbrial subunit proteins TsaA or TcfA TR:Q9XDS4 (EMBL:AB029403) (236 aa) fasta scores: E(): 0, 100.0% id in 236 aa, and to Escherichia coli cs1 fimbrial subunit B precursor CsoB or CooB SW:CSOB_ECOLI (P25731) (238 aa) fasta scores: E(): 5.3e-14, 34.6% id in 205 aa, and to Escherichia coli cfa/i fimbrial subunit A precursor cfaA SW:CFAA_ECOLI (P25732) (206 aa) fasta scores: E(): 1.4e-13, 32.8% id in 189 aa. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryoti [...] (236 aa)
STY0352Probable secreted protein; No database matches. Contains N-terminal signal sequence. (135 aa)
stbESimilar to Klebsiella pneumoniae chaperone protein MrkB precursor mrkB SW:MRKB_KLEPN (P21646) (233 aa) fasta scores: E(): 9.3e-21, 32.4% id in 204 aa, and to Bordetella pertussis chaperone protein fimb/fhad precursor fimb or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 1.8e-18, 31.7% id in 221 aa; Fasta hit to YRAI_ECOLI (231 aa), 32% identity in 222 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 32% identity in 213 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 30% identity in 207 aa overlap; Fasta hit to YBGP_ECOLI (242 aa), 31% identity in 229 aa overlap; Paralogue of E. co [...] (252 aa)
stbBSimilar to Escherichia coli chaperone protein EcpD precursor ecpD SW:ECPD_ECOLI (P33128) (246 aa) fasta scores: E(): 7.4e-32, 40.3% id in 248 aa, and to Bordetella pertussis chaperone protein fimb/fhad precursor fimb or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 3.2e-24, 38.5% id in 208 aa; Fasta hit to YEHC_ECOLI (239 aa), 39% identity in 258 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 34% identity in 233 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 33% identity in 236 aa overlap; Paralogue of E. coli ecpD (ECPD_ECOLI); Fasta hit to ECPD_ECOLI (246 aa), 40% identity in [...] (253 aa)
phnSProbable periplasmic binding component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import; Belongs to the bacterial solute-binding protein 1 family. (337 aa)
STY0498Putative solute-binding protein; Similar to Escherichia coli hypothetical protein YbaE SW:YBAE_ECOLI (P46890; P77158) (566 aa) fasta scores: E(): 0, 79.1% id in 565 aa. Also shows some similarity many ABC transporter periplasmic binding proteins e.g. to Bacillus subtilis oligopeptide-binding protein OppA or spo0kA SW:OPPA_BACSU (P24141; P23399) (545 aa) fasta scores: E(): 0.17, 40.0% id in 70 aa. Does not appear to contain an N-terminal signal sequence; Orthologue of E. coli ybaE (YBAE_ECOLI); Fasta hit to YBAE_ECOLI (566 aa), 79% identity in 565 aa overlap. (566 aa)
STY0542Conserved hypothetical protein; Orthologue of E. coli YBAP_ECOLI; Fasta hit to YBAP_ECOLI (264 aa), 65% identity in 264 aa overlap. (264 aa)
STY0552acyl-coA thioesterase I; Orthologue of E. coli tesA (TESA_ECOLI); Fasta hit to TESA_ECOLI (208 aa), 89% identity in 204 aa overlap. (204 aa)
fimCFimbrial chaperone protein; Similar to Salmonella typhi FimC gene fimC TR:Q56085 (EMBL:X74602) (237 aa) fasta scores: E(): 0, 100.0% id in 237 aa, and to Salmonella typhimurium chaperone protein FimC precursor fimC SW:FIMC_SALTY (P37923) (230 aa) fasta scores: E(): 0, 98.3% id in 230 aa; Fasta hit to YEHC_ECOLI (239 aa), 30% identity in 231 aa overlap; Fasta hit to YCBR_ECOLI (233 aa), 41% identity in 219 aa overlap; Fasta hit to YRAI_ECOLI (231 aa), 40% identity in 228 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 34% identity in 242 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 48% i [...] (230 aa)
STY0638Ferrienterobactin-binding periplasmic protein precursor; Orthologue of E. coli fepB (FEPB_ECOLI); Fasta hit to FEPB_ECOLI (318 aa), 79% identity in 318 aa overlap. (318 aa)
dsbGThiol:disulfide interchange protein DsbG precursor; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (248 aa)
STY0666Ribonuclease I precursor; Orthologue of E. coli rna (RNI_ECOLI); Fasta hit to RNI_ECOLI (268 aa), 74% identity in 268 aa overlap; Belongs to the RNase T2 family. (268 aa)
STY0688D-alanine carboxypeptidase; Fasta hit to DACC_ECOLI (400 aa), 60% identity in 401 aa overlap; Fasta hit to DACD_ECOLI (388 aa), 48% identity in 390 aa overlap; Orthologue of E. coli dacA (DACA_ECOLI); Fasta hit to DACA_ECOLI (403 aa), 95% identity in 403 aa overlap; Belongs to the peptidase S11 family. (403 aa)
STY0710Similar to Escherichia coli amino-acid ABC transporter binding protein YbeJ precursor ybeJ SW:YBEJ_ECOLI (P37902; P41408; P77612) (302 aa) fasta scores: E(): 0, 93.0% id in 302 aa, and to Bacillus stearothermophilus glutamine-binding protein precursor glnH SW:GLNH_BACST (P27676) (262 aa) fasta scores: E(): 3.6e-14, 30.4% id in 263 aa; Orthologue of E. coli ybeJ (YBEJ_ECOLI); Fasta hit to YBEJ_ECOLI (302 aa), 93% identity in 302 aa overlap. (308 aa)
STY0711Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (512 aa)
STY0729Similar to Salmonella typhi plasmid R27 hypothetical protein r0146 TR:Q9L5J6 (EMBL:AF250878) (467 aa) fasta scores: E(): 0, 93.1% id in 467 aa, and to Rhodobacter capsulatus hypothetical 86.4 kDa protein TR:O68107 (EMBL:AF010496) (828 aa) fasta scores: E(): 0, 37.8% id in 465 aa, and to Caenorhabditis elegans hypothetical 50.0 kDa protein F48e8.3 in chromosome iii f48e8.3 TR:Q09567 (EMBL:U23514) (474 aa) fasta scores: E(): 5.2e-07, 24.7% id in 478 aa. (467 aa)
STY0744Sensor protein KdpD; Orthologue of E. coli kdpD (KDPD_ECOLI); Fasta hit to KDPD_ECOLI (894 aa), 89% identity in 902 aa overlap. (902 aa)
STY0794tolB protein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa)
STY0796Putative exported protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (262 aa)
STY0814Molybdate-binding periplasmic protein precursor; Orthologue of E. coli modA (MODA_ECOLI); Fasta hit to MODA_ECOLI (257 aa), 86% identity in 257 aa overlap. (257 aa)
STY0868Glutamine-binding periplasmic protein precursor; Fasta hit to FLIY_ECOLI (266 aa), 34% identity in 257 aa overlap; Fasta hit to HISJ_ECOLI (260 aa), 32% identity in 257 aa overlap; Fasta hit to ARTI_ECOLI (243 aa), 33% identity in 244 aa overlap; Fasta hit to ARGT_ECOLI (260 aa), 35% identity in 254 aa overlap; Fasta hit to ARTJ_ECOLI (243 aa), 30% identity in 244 aa overlap; Orthologue of E. coli glnH (GLNH_ECOLI); Fasta hit to GLNH_ECOLI (248 aa), 97% identity in 248 aa overlap; Belongs to the bacterial solute-binding protein 3 family. (248 aa)
ybiSPutative exported protein; Similar to Escherichia coli protein YbiS precursor ybiS SW:YBIS_ECOLI (P75789) (306 aa) fasta scores: E(): 0, 92.5% id in 306 aa, and to Escherichia coli protein ErfK/srfk precursor erfK SW:ERFK_ECOLI (P39176) (310 aa) fasta scores: E(): 0, 65.8% id in 295 aa, and to Escherichia coli hypothetical 34.6 kDa protein in ndh-mfd intergenic region precursor ycfS SW:YCFS_ECOLI (P75954) (320 aa) fasta scores: E(): 0, 51.7% id in 302 aa. Contains probable N-terminal signal sequence; Fasta hit to YNHG_ECOLI (334 aa), 47% identity in 305 aa overlap; Fasta hit to YCFS_EC [...] (306 aa)
STY0886Similar to Escherichia coli putative L-asparaginase precursor ybiK SW:ASGX_ECOLI (P37595; P75795) (321 aa) fasta scores: E(): 0, 88.2% id in 313 aa, and to Arabidopsis thaliana L-asparaginase SW:ASPG_ARATH (P50287) (315 aa) fasta scores: E(): 0, 44.8% id in 299 aa, and to Lupinus luteus L-asparaginase SW:ASPG_LUPLU (Q9ZSD6) (325 aa) fasta scores: E(): 6.5e-16, 45.5% id in 308 aa; Orthologue of E. coli ybiK (ASGX_ECOLI); Fasta hit to ASGX_ECOLI (321 aa), 88% identity in 313 aa overlap. (313 aa)
yliBPutative ABC transporter periplasmic binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Binds glutathione. (512 aa)
yliIPutative oxidoreductase; Similar to Escherichia coli hypothetical 41.1 kDa protein in moea-dacc intergenic region precursor yliI SW:YLII_ECOLI (P75804) (371 aa) fasta scores: E(): 0, 77.2% id in 369 aa, and to Acinetobacter calcoaceticus glucose dehydrogenase-b [pyrroloquinoline-quinone] precursor gdhB SW:DHGB_ACICA (P13650) (478 aa) fasta scores: E(): 8.9e-08, 27.2% id in 452 aa; Orthologue of E. coli YLII_ECOLI; Fasta hit to YLII_ECOLI (371 aa), 77% identity in 369 aa overlap. (373 aa)
STY0896D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6 precursor); Fasta hit to DACD_ECOLI (388 aa), 47% identity in 384 aa overlap; Fasta hit to DACA_ECOLI (403 aa), 61% identity in 397 aa overlap; Orthologue of E. coli dacC (DACC_ECOLI); Fasta hit to DACC_ECOLI (400 aa), 92% identity in 400 aa overlap; Belongs to the peptidase S11 family. (400 aa)
STY0910Putrescine-binding periplasmic protein precursor; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (370 aa)
STY0920Arginine-binding periplasmic protein 2 precursor; Fasta hit to HISJ_ECOLI (260 aa), 41% identity in 256 aa overlap; Fasta hit to FLIY_ECOLI (266 aa), 33% identity in 220 aa overlap; Fasta hit to ARTI_ECOLI (243 aa), 63% identity in 243 aa overlap; Fasta hit to ARGT_ECOLI (260 aa), 39% identity in 253 aa overlap; Fasta hit to GLNH_ECOLI (248 aa), 32% identity in 244 aa overlap; Orthologue of E. coli artJ (ARTJ_ECOLI); Fasta hit to ARTJ_ECOLI (243 aa), 91% identity in 243 aa overlap; Belongs to the bacterial solute-binding protein 3 family. (243 aa)
STY0923Arginine-binding periplasmic protein 1 precursor; Fasta hit to HISJ_ECOLI (260 aa), 40% identity in 255 aa overlap; Fasta hit to FLIY_ECOLI (266 aa), 31% identity in 252 aa overlap; Fasta hit to ARGT_ECOLI (260 aa), 36% identity in 253 aa overlap; Fasta hit to ARTJ_ECOLI (243 aa), 63% identity in 243 aa overlap; Fasta hit to GLNH_ECOLI (248 aa), 34% identity in 244 aa overlap; Orthologue of E. coli artI (ARTI_ECOLI); Fasta hit to ARTI_ECOLI (243 aa), 95% identity in 243 aa overlap; Belongs to the bacterial solute-binding protein 3 family. (243 aa)
STY0925Probable lipoprotein; Orthologue of E. coli YBJP_ECOLI; Fasta hit to YBJP_ECOLI (171 aa), 84% identity in 171 aa overlap. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (171 aa)
STY0959Outer membrane lipoprotein carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa)
STY0998Putative exported protein; Orthologue of E. coli YCBK_ECOLI; Fasta hit to YCBK_ECOLI (182 aa), 95% identity in 182 aa overlap. Contains a possible N-terminal signal sequence. (182 aa)
STY1085Putative secreted protein; Similar to Neisseria meningitidis hypothetical integral membrane protein NMA1929 TR:CAB85149 (EMBL:AL162757) fasta scores: E(): 0, 35.2% id in 549 aa; Orthologue of E. coli pqiB (PQIB_ECOLI); Fasta hit to PQIB_ECOLI (546 aa), 89% identity in 546 aa overlap. (546 aa)
STY1086Putative lipoprotein; Similar to Neisseria meningitidis putative lipoprotein NMA1930 TR:CAB85150 (EMBL:AL162757) fasta scores: E(): 2e-09, 34.3% id in 178 aa; Orthologue of E. coli YMBA_ECOLI; Fasta hit to YMBA_ECOLI (182 aa), 84% identity in 182 aa overlap. (187 aa)
scsCSimilar to Salmonella typhimurium suppressor for copper-sensitivity C precursor ScsC TR:O33919 (EMBL:U75949) fasta scores: E(): 0, 97.1% id in 207 aa. (207 aa)
STY1153Glucose-1-phosphatase precursor (G1Pase), secreted; Fasta hit to PPA_ECOLI (432 aa), 33% identity in 409 aa overlap; Orthologue of E. coli agp (AGP_ECOLI); Fasta hit to AGP_ECOLI (413 aa), 83% identity in 413 aa overlap. (413 aa)
STY1167Conserved hypothetical protein; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family. (384 aa)
STY1182Conserved hypothetical protein; Orthologue of E. coli CSGC_ECOLI; Fasta hit to CSGC_ECOLI (110 aa), 73% identity in 108 aa overlap. (108 aa)
STY1187Periplasmic glucans biosynthesis protein MdoG precursor; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (511 aa)
STY1194Putative exported protein; Orthologue of E. coli yceI (YCEI_ECOLI); Fasta hit to YCEI_ECOLI (191 aa), 91% identity in 191 aa overlap. Contains a possible N-terminal signal sequence. (191 aa)
STY1212Flagellar basal body P-ring protein FlgA precursor; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (219 aa)
STY1221Flagellar protein FlgJ; Orthologue of E. coli flgJ (FLGJ_ECOLI); Fasta hit to FLGJ_ECOLI (313 aa), 83% identity in 316 aa overlap. (316 aa)
STY1255Putative exported protein; Fasta hit to ERFK_ECOLI (310 aa), 52% identity in 254 aa overlap; Fasta hit to YBIS_ECOLI (306 aa), 52% identity in 262 aa overlap; Orthologue of E. coli YCFS_ECOLI; Fasta hit to YCFS_ECOLI (320 aa), 87% identity in 263 aa overlap. Contains a possible N-terminal signal sequence. Short C-terminal truncation relative to E. coli. (263 aa)
STY1257ABC transporter integral membrane subunit; Orthologue of E. coli YCFU_ECOLI; Fasta hit to YCFU_ECOLI (399 aa), 94% identity in 399 aa overlap. (436 aa)
STY1262Spermidine/putrescine-binding periplasmic protein precursor; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein (By similarity); Belongs to the bacterial solute-binding protein PotD/PotF family. (348 aa)
STY1304Periplasmic oligopeptide-binding protein precursor; Fasta hit to YGIS_ECOLI (535 aa), 45% identity in 530 aa overlap; Fasta hit to MPPA_ECOLI (537 aa), 49% identity in 523 aa overlap; Orthologue of E. coli oppA (OPPA_ECOLI); Fasta hit to OPPA_ECOLI (543 aa), 84% identity in 543 aa overlap. (582 aa)
STY1369Peptide transport periplasmic protein SapA precursor; Fasta hit to DPPA_ECOLI (535 aa), 37% identity in 516 aa overlap; Orthologue of E. coli sapA (SAPA_ECOLI); Fasta hit to SAPA_ECOLI (547 aa), 90% identity in 549 aa overlap. (549 aa)
STY1375Phage shock protein E precursor; Orthologue of E. coli pspE (PSPE_ECOLI); Fasta hit to PSPE_ECOLI (104 aa), 67% identity in 103 aa overlap. (104 aa)
STY1384Periplasmic murein peptide-binding protein MppA; Fasta hit to YGIS_ECOLI (535 aa), 43% identity in 527 aa overlap; Fasta hit to OPPA_ECOLI (543 aa), 48% identity in 539 aa overlap; Orthologue of E. coli MPPA_ECOLI; Fasta hit to MPPA_ECOLI (537 aa), 92% identity in 537 aa overlap. (537 aa)
STY1421Heat shock protein; Orthologue of E. coli hslJ (HSLJ_ECOLI); Fasta hit to HSLJ_ECOLI (140 aa), 70% identity in 138 aa overlap. (136 aa)
STY1438Putative periplasmic amino acid-binding protein; Similar to Escherichia coli glutamine-binding periplasmic protein precursor glnH SW:GLNH_ECOLI (P10344) (248 aa) fasta scores: E(): 1.3e-10, 26.4% id in 235 aa. (253 aa)
STY1442Putative exported protein; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs); Belongs to the OpgD/OpgG family. (541 aa)
STY1501Putative secreted protein; Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. Belongs to the HdeB family. (109 aa)
STY1522Putative secreted hydrolase; Similar to Clostridium perfringens choloylglycine hydrolase SW:CBH_CLOPE (P54965) (329 aa) fasta scores: E(): 1.6e-13, 31.5% id in 238 aa. (363 aa)
STY1533Putative exported protein; No significant database matches. (180 aa)
STY1549Dipeptidyl carboxypeptidase II; Fasta hit to OPDA_ECOLI (680 aa), 32% identity in 685 aa overlap; Orthologue of E. coli dcp (DCP_ECOLI); Fasta hit to DCP_ECOLI (680 aa), 79% identity in 678 aa overlap. (680 aa)
STY1571Putative ABC transporter periplasmic binding protein; Similar to Streptomyces coelicolor proxl or sce19a.33 TR:Q9X4J2 (EMBL:AF112365) (322 aa) fasta scores: E(): 1e-32, 39.1% id in 279 aa, and to Bacillus subtilis glycine betaine/carnitine/choline-binding protein precursor opucC SW:OPCC_BACSU (O32243; O31407) (303 aa) fasta scores: E(): 1.4e-14, 30.9% id in 272 aa. (300 aa)
STY1582Putative secreted stress response protein; Required for growth and/or survival at acidic conditions. (93 aa)
STY1682Copper-zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (173 aa)
ssaJPutative pathogenicity island lipoprotein; Similar to Salmonella typhimurium secretion system apparatus lipoprotein SsaJ SW:SSAJ_SALTY () (249 aa) fasta scores: E(): 0, 98.8% id in 249 aa. (249 aa)
ttrBSimilar to Salmonella typhimurium tetrathionate reductase subunit B TtrB TR:Q9Z4S8 (EMBL:AJ224978) (250 aa) fasta scores: E(): 0, 100.0% id in 250 aa and to Salmonella typhimurium thiosulfate reductase electron transport protein PhsB SW:PHSB_SALTY (P37601) (192 aa) fasta scores: E(): 1.1e-25, 46.4% id in 151 aa; Fasta hit to P77375 (239 aa), 33% identity in 228 aa overlap; Paralogue of E. coli nrfC (NRFC_ECOLI); Fasta hit to NRFC_ECOLI (223 aa), 41% identity in 222 aa overlap. (250 aa)
STY1805Putative exported protein; Similar to Escherichia coli spheroplast protein Y precursor spy SW:SPY_ECOLI (P77754) (161 aa) fasta scores: E(): 0, 88.2% id in 161 aa, and to Escherichia coli periplasmic protein CpxP precursor. periplasmic protein CpxP precursor SW:CPXP_ECOLI () (166 aa) fasta scores: E(): 3.1e-08, 30.4% id in 148 aa; Fasta hit to CPXP_ECOLI (166 aa), 30% identity in 148 aa overlap. (161 aa)
aroQPutative chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (181 aa)
STY1858Similar to Escherichia coli hypothetical 24.8 kDa protein in dcm-shia intergenic region yodA SW:YODA_ECOLI (P76344) (216 aa) fasta scores: E(): 0, 71.8% id in 216 aa, and to Bacillus anthracis pxo1-130 TR:Q9X387 (EMBL:AF065404) (237 aa) fasta scores: E(): 5.5e-33, 43.3% id in 194 aa. (216 aa)
STY1865Similar to Salmonella typhimurium putative substrate-binding protein oxd-6A TR:O34156 (EMBL:U94729) (528 aa) fasta scores: E(): 0, 98.9% id in 528 aa, and to Escherichia coli hypothetical 36.5 kDa protein in ureR 3'region TR:Q05633 (EMBL:L12007) (336 aa) fasta scores: E(): 0, 63.0% id in 319 aa, and to Streptomyces coelicolor putative substrate binding protein SC9B5.18 TR:Q9ZBG2 (EMBL:AL035206) (542 aa) fasta scores: E(): 6.1e-28, 30.7% id in 515 aa. (544 aa)
STY1976Tail-specific protease precursor; Orthologue of E. coli prc (PRC_ECOLI); Fasta hit to PRC_ECOLI (682 aa), 93% identity in 682 aa overlap; Belongs to the peptidase S41A family. (682 aa)
STY1980Similar to Escherichia coli hypothetical 95.0 kDa protein in proQ-pphA intergenic region TR:P76272 (EMBL:AE000277) (879 aa) fasta scores: E(): 0, 90.4% id in 879 aa, and to Haemophilus influenzae hypothetical protein Hi1672 SW:YG72_HAEIN (P44288) (881 aa) fasta scores: E(): 0, 42.6% id in 876 aa. (879 aa)
STY2004Putative hydrolase; Similar to Escherichia coli hypothetical protein yjcS SW:YJCS_ECOLI (P32717) (661 aa) fasta scores: E(): 0, 47.6% id in 660 aa. Similar to hypothetical proteins from eubacteria and eukaryotes e.g. Saccharomyces cerevisiae chromosome XV reading frame ORF yol164W, TR:Q08347 (EMBL:Z74906) (646 aa) fasta scores: E(): 0, 50.3% id in 634 aa and Mycobacterium tuberculosis hypothetical protein Rv3762c, TR:O69728 (EMBL:AL022121) (626 aa) fasta scores: E(): 0, 46.1% id in 631 aa. Also similar to Listeria monocytogenes sepA TR:Q48790 (EMBL:X92423) (391 aa) fasta scores: E(): 0 [...] (659 aa)
STY2081Similar to Xanthomonas campestris copper resistance protein C precursor SW:COPC_XANCJ (Q56797) (127 aa) fasta scores: E(): 1.6e-09, 34.7% id in 118 aa, and to Escherichia coli copper resistance protein C precursor pcoC SW:COPC_ECOLI (Q47454) (126 aa) fasta scores: E(): 2.9e-08, 41.1% id in 112 aa. Contains a probable N-terminal signal sequence; Orthologue of E. coli YOBA_ECOLI; Fasta hit to YOBA_ECOLI (124 aa), 73% identity in 124 aa overlap. (126 aa)
STY2099High-affinity zinc uptake system periplasmic binding protein; Orthologue of E. coli yebL (ZNUA_ECOLI); Fasta hit to ZNUA_ECOLI (328 aa), 87% identity in 319 aa overlap; Contains probable N-terminal signal sequence. (319 aa)
fliYSimilar to Escherichia coli cystine-binding periplasmic protein precursor fliY SW:FLIY_ECOLI (P39174) (266 aa) fasta scores: E(): 0, 92.5% id in 266 aa and Salmonella typhimurium FliY fliY TR:Q9ZNM2 (EMBL:AB010947) (266 aa) fasta scores: E(): 0, 98.9% id in 266 aa. Contains a probable N-terminal signal sequence; Orthologue of E. coli fliY (FLIY_ECOLI); Fasta hit to FLIY_ECOLI (266 aa), 93% identity in 266 aa overlap; Belongs to the bacterial solute-binding protein 3 family. (266 aa)
STY2218Putative exported protein; Similar to Salmonella typhimurium protein erfK/srfK precursor SW:ERFK_SALTY (P40680) (309 aa) fasta scores: E(): 0, 99.0% id in 309 aa. Contains probable N-terminal signal sequence; Fasta hit to YNHG_ECOLI (334 aa), 47% identity in 288 aa overlap; Fasta hit to YCFS_ECOLI (320 aa), 48% identity in 307 aa overlap; Fasta hit to YBIS_ECOLI (306 aa), 66% identity in 283 aa overlap; Orthologue of E. coli erfK (ERFK_ECOLI); Fasta hit to ERFK_ECOLI (310 aa), 79% identity in 305 aa overlap. (309 aa)
yohNSimilar to Escherichia coli hypothetical protein yohN SW:YOHN_ECOLI (P76426) (112 aa) fasta scores: E(): 0, 80.9% id in 110 aa. (104 aa)
stcBSimilar to many e.g. Klebsiella pneumoniae chaperone protein MrkB precursor mrkB SW:MRKB_KLEPN (P21646) (233 aa) fasta scores: E(): 6.1e-26, 35.7% id in 235 aa and Bordetella pertussis chaperone protein precursor fimB or fhaD SW:FIMB_BORPE (P33409) (244 aa) fasta scores: E(): 8.7e-23, 33.8% id in 231 aa; Fasta hit to YRAI_ECOLI (231 aa), 30% identity in 220 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 33% identity in 216 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 35% identity in 222 aa overlap; Orthologue of E. coli yehC (YEHC_ECOLI); Fasta hit to YEHC_ECOLI (239 aa), 64% identity [...] (227 aa)
STY2395Putative periplasmic protein; Similar to e.g. Deinococcus radiodurans ABC transporter, periplasmic substrate-binding protein, putative DRA0135 TR:Q9RZ18 (EMBL:AE001862) (369 aa) fasta scores: E(): 0, 51.7% id in 296 aa and Streptomyces coelicolor probable permease binding protein proXL or SCE19A.33 TR:Q9X4J2 (EMBL:AF112365) (322 aa) fasta scores: E(): 1.3e-22, 31.4% id in 287 aa. Contains probable N-terminal signal sequence; Orthologue of E. coli yehZ (YEHZ_ECOLI); Fasta hit to YEHZ_ECOLI (305 aa), 88% identity in 305 aa overlap. (305 aa)
STY2396Similar to Salmonella typhimurium periplasmic beta-glucosidase precursor SW:BGLX_SALTY (Q56078) (765 aa) fasta scores: E(): 0, 99.0% id in 765 aa. Contains probable N-terminal signal sequence; Orthologue of E. coli bglX (BGLX_ECOLI); Fasta hit to BGLX_ECOLI (765 aa), 93% identity in 765 aa overlap; Belongs to the glycosyl hydrolase 3 family. (765 aa)
STY2424Similar to Salmonella typhimurium D-galactose-binding periplasmic protein precursor mglB SW:DGAL_SALTY (P23905) (332 aa) fasta scores: E(): 0, 99.1% id in 332 aa; Orthologue of E. coli mglB (DGAL_ECOLI); Fasta hit to DGAL_ECOLI (332 aa), 93% identity in 332 aa overlap. (332 aa)
STY2452Putative transport system periplasmic binding protein; Orthologue of E. coli yejA (YEJA_ECOLI); Fasta hit to YEJA_ECOLI (604 aa), 86% identity in 601 aa overlap. Contains probable N-terminal signal sequence. (601 aa)
STY2482Cytochrome c-type protein NapB precursor; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (149 aa)
STY2485Probable nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa)
STY2488Ecotin precursor; General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. (164 aa)
rcsCSensor protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa)
STY2511Glycerophosphoryl diester phosphodiesterase periplasmic precursor; Orthologue of E. coli glpQ (GLPQ_ECOLI); Fasta hit to GLPQ_ECOLI (358 aa), 89% identity in 357 aa overlap. (356 aa)
STY2584Similar to Salmonella typhimurium histidine-binding periplasmic protein precursor hisJ SW:HISJ_SALTY (P02910) (260 aa) fasta scores: E(): 0, 99.2% id in 260 aa; Fasta hit to ARTI_ECOLI (243 aa), 39% identity in 255 aa overlap; Fasta hit to ARGT_ECOLI (260 aa), 67% identity in 259 aa overlap; Fasta hit to ARTJ_ECOLI (243 aa), 41% identity in 255 aa overlap; Fasta hit to GLNH_ECOLI (248 aa), 30% identity in 257 aa overlap; Orthologue of E. coli hisJ (HISJ_ECOLI); Fasta hit to HISJ_ECOLI (260 aa), 97% identity in 260 aa overlap; Belongs to the bacterial solute-binding protein 3 family. (260 aa)
STY2585Similar to Salmonella typhimurium lysine-arginine-ornithine-binding periplasmic protein precursor argT SW:ARGT_SALTY (P02911) (260 aa) fasta scores: E(): 0, 99.2% id in 260 aa; Fasta hit to HISJ_ECOLI (260 aa), 68% identity in 259 aa overlap; Fasta hit to ARTI_ECOLI (243 aa), 34% identity in 255 aa overlap; Fasta hit to ARTJ_ECOLI (243 aa), 36% identity in 254 aa overlap; Fasta hit to GLNH_ECOLI (248 aa), 32% identity in 253 aa overlap; Orthologue of E. coli argT (ARGT_ECOLI); Fasta hit to ARGT_ECOLI (260 aa), 92% identity in 260 aa overlap; Belongs to the bacterial solute-binding prot [...] (260 aa)
STY2615Penicillin-insensitive murein endopeptidase precursor; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. (274 aa)
pgtCPhosphoglycerate transport regulatory protein PgtC precursor; Required for pgtP expression, it may act jointly with the PgtA/PgtB signaling proteins. (397 aa)
STY2681Similar to Salmonella typhimurium thiosulphate-binding protein precursor cysP SW:CYSP_SALTY (P41031) (338 aa) fasta scores: E(): 0, 97.3% id in 338 aa; Fasta hit to SUBI_ECOLI (329 aa), 47% identity in 320 aa overlap; Orthologue of E. coli cysP (CYSP_ECOLI); Fasta hit to CYSP_ECOLI (338 aa), 94% identity in 337 aa overlap. (338 aa)
STY2687Similar to Salmonella typhimurium probable N-acetylmuramoyl-L-alanine amidase amiA precursor SW:AMIA_SALTY (P33772) (289 aa) fasta scores: E(): 0, 99.7% id in 289 aa; Orthologue of E. coli amiA (AMIA_ECOLI); Fasta hit to AMIA_ECOLI (289 aa), 93% identity in 289 aa overlap. (289 aa)
STY2735Putative exported protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (487 aa)
STY2810Putative membrane protein; Orthologue of E. coli yfhG (YFHG_ECOLI); Fasta hit to YFHG_ECOLI (237 aa), 62% identity in 247 aa overlap. The start codon may be at codon 8, in which case this protein has a possible N-terminal signal sequence and may be a lipoprotein as it would then have an appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (254 aa)
STY2831sigma-E factor regulatory protein RseB precursor; Orthologue of E. coli rseB (RSEB_ECOLI); Fasta hit to RSEB_ECOLI (318 aa), 89% identity in 318 aa overlap. Contains a probable N-terminal signal sequence. (318 aa)
STY2906Putative exported protein; Similar to Bacillus subtilis hypothetical YflP protein yflP TR:O34439 (EMBL:Z99108) (259 aa) fasta scores: E(): 1.7e-11, 26.6% id in 222 aa. Similar to ORFs from Comamonas testosteroni 3-(3-hydroxyphenyl)propionic acid degradation pathway and Alcaligenes eutrophus pathway for biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate); Alcaligenes eutrophus hypothetical protein SW:YGB7_ALCEU (Q44018) (327 aa) fasta scores: E(): 3.6e-10, 27.2% id in 217 aa and Comamonas testosteroni ORF5 protein TR:Q9S154 (EMBL:AB024335) (278 aa) fasta scores: E(): 3.4e-06, 2 [...] (269 aa)
STY2937Glycine betaine-binding periplasmic protein precursor; Orthologue of E. coli proX (PROX_ECOLI); Fasta hit to PROX_ECOLI (330 aa), 83% identity in 331 aa overlap. (331 aa)
STY2940Multidrug resistance protein A; Fasta hit to EMRK_ECOLI (387 aa), 50% identity in 377 aa overlap; Orthologue of E. coli emrA (EMRA_ECOLI); Fasta hit to EMRA_ECOLI (390 aa), 90% identity in 390 aa overlap. (390 aa)
STY2952Membrane-bound lytic transglycosylase B precursor; Orthologue of E. coli mltB (MLTB_ECOLI); Fasta hit to MLTB_ECOLI (361 aa), 92% identity in 361 aa overlap. (359 aa)
sitASimilar to Salmonella typhimurium SitA, an iron transport protein located on centisome 63 pathogenicity island TR:Q9XCS2 (EMBL:AF128999) (305 aa) fasta scores: E(): 0, 100.0% id in 305 aa and to Yersinia pestis YfeA TR:Q56952 (EMBL:U50597) (322 aa) fasta scores: E(): 0, 62.2% id in 275 aa; Belongs to the bacterial solute-binding protein 9 family. (305 aa)
prgKPathogenicity 1 island effector protein; Similar to several proteins essential for protein secretion by a type III system: Salmonella typhimurium protein precursor PrgK required for invasion of epithelial cells SW:PRGK_SALTY (P41786) (252 aa) fasta scores: E(): 0, 99.6% id in 252 aa and Shigella flexneri lipoprotein MxiJ secretion protein SW:MXIJ_SHIFL (Q06081) (241 aa) fasta scores: E(): 0, 46.1% id in 243 aa. Contains a possible N-terminal signal sequence. (252 aa)
iapAlkaline phosphatase isozyme conversion protein; Orthologue of E. coli iap (IAP_ECOLI); Fasta hit to IAP_ECOLI (345 aa), 85% identity in 344 aa overlap. (348 aa)
STY3078MBL fold metallo-hydrolase; Similar to hypothetical proteins of archeal origin e.g. Pyrococcus abyssi hypothetical 30.2 kDa protein pab0518 TR:Q9V0M3 (EMBL:AJ248285) (272 aa) fasta scores: E(): 3.5e-26, 38.7% id in 261 aa, and to Methanobacterium thermoautotrophicum conserved protein mth1101 TR:O27173 (EMBL:AE000880) (260 aa) fasta scores: E(): 2.3e-16, 31.5% id in 251 aa, and to Methanococcus jannaschii hypothetical protein Mj0448 mj0448 SW:Y448_METJA (Q57890) (256 aa) fasta scores: E(): 7.3e-15, 29.4% id in 248 aa, and to Archaeoglobus fulgidus conserved hypothetical protein af0719 T [...] (265 aa)
steCSimilar to Salmonella typhimurium periplasmic fimbrial chaperone StfD TR:O87659 (EMBL:AF093503) (250 aa) fasta scores: E(): 0, 52.4% id in 250 aa and to Escherichia coli hypothetical fimbrial chaperone SW:YFCS_ECOLI (250 aa) fasta scores: E(): 0, 52.1% id in 238 aa; Orthologue of E. coli YFCS_ECOLI; Fasta hit to YFCS_ECOLI (250 aa), 52% identity in 238 aa overlap. (257 aa)
STY3128Membrane-bound lytic murein transglycosylase A precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (365 aa)
STY3129Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiC precursor SW:AMIC_ECOLI () (417 aa) fasta scores: E(): 0, 94.2% id in 416 aa. Contains a possible N-terminal signal sequence; Fasta hit to AMIB_ECOLI (445 aa), 31% identity in 414 aa overlap; Orthologue of E. coli AMIC_ECOLI; Fasta hit to AMIC_ECOLI (417 aa), 94% identity in 416 aa overlap. (417 aa)
stdCWeakly similar to Escherichia coli chaperone protein PapD involved in pili assembly SW:PAPD_ECOLI (P15319) (239 aa) fasta scores: E(): 5.9e-33, 37.8% id in 238 aa; Paralogue of E. coli YBGP_ECOLI; Fasta hit to YBGP_ECOLI (242 aa), 40% identity in 222 aa overlap. (247 aa)
STY3199Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (237 aa)
STY3246Orthologue of E. coli endA (END1_ECOLI); Fasta hit to END1_ECOLI (235 aa), 87% identity in 235 aa overlap. (235 aa)
STY3259L-asparaginase; Highly similar to Escherichia coli L-asparaginase II precursor AnsB SW:ASG2_ECOLI (P00805) (348 aa) fasta scores: E(): 0, 92.8% id in 348 aa. Contains a possible N-terminal signal sequence; Belongs to the asparaginase 1 family. (348 aa)
STY3312Hypothetical protein; Weakly similar to Deinococcus radiodurans molybdenum ABC transporter, periplasmic molybdate-binding protein, putative dra0169 TR:Q9RYY4 (EMBL:AE001862) (251 aa) fasta scores: E(): 1.2e-05, 25.1% id in 239 aa. (237 aa)
STY3313Possible ABC-transport protein, periplasmic-binding component; Similar to several including: Haemophilus influenzae hypothetical protein HI1472 SW:YE72_HAEIN (P44206) (351 aa) fasta scores: E(): 0, 57.7% id in 343 aa and Archaeoglobus fulgidus iron (III) ABC transporter, ATP-binding protein AF0432 TR:O29817 (EMBL:AE001075) (366 aa) fasta scores: E(): 2e-12, 29.0% id in 362 aa. Contains a possible N-terminal signal sequence. (350 aa)
STY3320Hydrogenase-2 small subunit; Fasta hit to FDNH_ECOLI (294 aa), 32% identity in 305 aa overlap; Orthologue of E. coli hybA (HYBA_ECOLI); Fasta hit to HYBA_ECOLI (328 aa), 95% identity in 328 aa overlap. (328 aa)
STY3349SufI protein; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress. (470 aa)
dsbADisulfide isomerase; Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT. (223 aa)
STY3479Penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase); Orthologue of E. coli dacB (PBP4_ECOLI); Fasta hit to PBP4_ECOLI (477 aa), 94% identity in 477 aa overlap. (477 aa)
STY3489Possible exported protein; Orthologue of E. coli yrbC (YRBC_ECOLI); Fasta hit to YRBC_ECOLI (211 aa), 94% identity in 211 aa overlap. Contains a possible N-terminal signal sequence. (211 aa)
STY3496Possible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa)
STY3497Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (172 aa)
degQSerine protease; Similar to Escherichia coli protease DegQ SW:DEGQ_ECOLI (P39099) (455 aa) fasta scores: E(): 0, 90.1% id in 455 aa; Belongs to the peptidase S1C family. (455 aa)
STY3557Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The [...] (334 aa)
STY3713Possible exported protein; Binds zinc. Could be an important component of the zinc- balancing mechanism (By similarity); Belongs to the ZraP family. (151 aa)
STY3765Hypothetical protein; Similar to several 5' nucleosidase family proteins e.g. Thermotoga maritima UDP-sugar hydrolase TR:Q9X2J1 (EMBL:AE001824) (508 aa) fasta scores: E(): 1.1e-30, 32.6% id in 509 aa; Belongs to the 5'-nucleotidase family. (518 aa)
STY3808Periplasmic sulphate binding protein; Fasta hit to CYSP_ECOLI (338 aa), 46% identity in 323 aa overlap; Orthologue of E. coli sbp (SUBI_ECOLI); Fasta hit to SUBI_ECOLI (329 aa), 94% identity in 329 aa overlap. (329 aa)
STY3811Extracytoplasmic stress protein for protein-mediated toxicities; Similar to Escherichia coli periplasmic protein CpxP precursor SW:CPXP_ECOLI () (166 aa) fasta scores: E(): 0, 88.6% id in 166 aa. Contains a possible N-terminal signal sequence; Fasta hit to SPY_ECOLI (161 aa), 32% identity in 159 aa overlap. (166 aa)
STY3813Similar to Escherichia coli sensor protein governing extracytoplasmic protein-mediated toxicities CpxA SW:CPXA_ECOLI (P08336) (457 aa) fasta scores: E(): 0, 96.9% id in 457 aa. (457 aa)
STY3883Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis (By similarity). Belongs to the thioredoxin family. DsbA subfamily. (207 aa)
STY3894D-ribose-binding periplasmic protein; Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose. (296 aa)
stgBSimilar to Escherichia coli chaperone protein precursor FocC SW:FOCC_ECOLI (P46008) (227 aa) fasta scores: E(): 1.1e-24, 34.9% id in 215 aa; Fasta hit to YRAI_ECOLI (231 aa), 38% identity in 219 aa overlap; Fasta hit to YBGP_ECOLI (242 aa), 34% identity in 224 aa overlap; Fasta hit to YEHC_ECOLI (239 aa), 32% identity in 226 aa overlap; Fasta hit to YFCS_ECOLI (250 aa), 34% identity in 231 aa overlap; Fasta hit to SFMC_ECOLI (230 aa), 35% identity in 226 aa overlap; Fasta hit to ECPD_ECOLI (246 aa), 36% identity in 226 aa overlap; Fasta hit to FIMC_ECOLI (241 aa), 34% identity in 215 a [...] (232 aa)
STY3923Conserved hypothetical protein; Fasta hit to YBAE_ECOLI (566 aa), 31% identity in 599 aa overlap; Paralogue of E. coli yabN (YABN_ECOLI); Fasta hit to YABN_ECOLI (551 aa), 40% identity in 583 aa overlap. (585 aa)
STY3926Periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
STY3952Solute binding receptor protein; Orthologue of E. coli torT (TORT_ECOLI); Fasta hit to TORT_ECOLI (342 aa), 67% identity in 346 aa overlap. (346 aa)
yhjASimilar to Escherichia coli probable cytochrome c peroxidase yhjA SW:YHJA_ECOLI (P37197) (465 aa) fasta scores: E(): 0, 82.5% id in 462 aa, and to Pseudomonas aeruginosa cytochrome c551 peroxidase precursor ccpa or pa4587 SW:CCPR_PSEAE (P14532) (346 aa) fasta scores: E(): 0, 42.0% id in 305 aa; Orthologue of E. coli yhjA (YHJA_ECOLI); Fasta hit to YHJA_ECOLI (465 aa), 83% identity in 462 aa overlap. (466 aa)
STY3967Putative ATP/GTP-binding protein; Orthologue of E. coli yidR (YIDR_ECOLI); Fasta hit to YIDR_ECOLI (416 aa), 80% identity in 408 aa overlap. (408 aa)
STY4090Similar to Escherichia coli hypothetical 46.6 kDa protein in secB-tdh intergenic region yibP SW:YIBP_ECOLI (P37690) (419 aa) fasta scores: E(): 0, 91.6% id in 419 aa, and to Haemophilus influenzae hypothetical protein Hi0756 hi0756 SW:YIBP_HAEIN (P44864) (410 aa) fasta scores: E(): 0, 41.7% id in 403 aa. Contains coiled-coil regions. (427 aa)
STY4134Alpha-amylase; Orthologue of E. coli malS (AMY1_ECOLI); Fasta hit to AMY1_ECOLI (676 aa), 82% identity in 676 aa overlap. Contains a probable N-terminal signal sequence. (675 aa)
bisCSimilar to Escherichia coli biotin sulfoxide reductase 1 bisC SW:BISC_ECOLI (P20099) (777 aa) fasta scores: E(): 0, 85.5% id in 777 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (777 aa)
STY4168Periplasmic dipeptide transport protein precursor; Fasta hit to SAPA_ECOLI (547 aa), 36% identity in 513 aa overlap; Orthologue of E. coli dppA (DPPA_ECOLI); Fasta hit to DPPA_ECOLI (535 aa), 93% identity in 535 aa overlap. (535 aa)
STY4200Cytoplasmic trehalase; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity. (549 aa)
STY4237Putative membrane protein; Similar to Escherichia coli hypothetical 13.5 kDa protein in ftsY-nikA intergenic region YhhM SW:YHHM_ECOLI (P37615) (119 aa) fasta scores: E(): 0, 85.3% id in 116 aa. N-terminal hydrophobic region, probable membrane spanning domain. (123 aa)
STY4248Leucine-specific binding protein; This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids; Belongs to the leucine-binding protein family. (369 aa)
STY4254Glycerol-3-phosphate-binding periplasmic protein; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa)
ggtSimilar to Escherichia coli gamma-glutamyltranspeptidase precursor ggt SW:GGT_ECOLI (P18956) (580 aa) fasta scores: E(): 0, 91.4% id in 580 aa, and to Helicobacter pylori J99 gamma-glutamyltranspeptidase ggt TR:Q9ZK95 (EMBL:AE001532) (567 aa) fasta scores: E(): 0, 52.7% id in 537 aa. Contains N-terminal signal sequence, probable secreted protein. (580 aa)
envZTwo-component sensor kinase EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in regulating expression of the outer membrane porins OmpC and OmpF as well as other genes. Unlike E.coli or S.typhimurium both porins are expressed constitutively. Involved in regulation of the biosynthesis of Vi polysaccharide, a capsular antigen thought to be involved in the virulence of S.typhi. Vi antigen is synthesized at low NaCl concentrations (under 0.4 M). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals (By sim [...] (450 aa)
ppiAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (190 aa)
fkpASimilar to Escherichia coli fkbp-type peptidyl-prolyl cis-trans isomerase FkpA precursor fkpA SW:FKBA_ECOLI (P45523) (270 aa) fasta scores: E(): 0, 89.7% id in 272 aa, and to Aeromonas hydrophila fkbp-type peptidyl-prolyl cis-trans isomerase FkpA precursor fkpA SW:FKBA_AERHY (O08437) (268 aa) fasta scores: E(): 0, 44.0% id in 266 aa. (272 aa)
STY4420Putative exported protein; Similar to Escherichia coli hypothetical 26.3 kDa protein in pgi-xylE intergenic region YjbG SW:YJBG_ECOLI (P32688) (245 aa) fasta scores: E(): 0, 74.3% id in 245 aa, and to Escherichia coli hypothetical 27.3 kDa protein in appA-cspH intergenic region YmcB SW:YMCB_ECOLI (P75883) (248 aa) fasta scores: E(): 9.4e-32, 40.2% id in 239 aa. Contains N-terminal signal sequence, probable secreted protein. (244 aa)
STY4421Putative lipoprotein; Similar to Escherichia coli hypothetical lipoprotein YjbH SW:YJBH_ECOLI (P32689) (698 aa) fasta scores: E(): 0, 92.3% id in 698 aa and to Escherichia coli hypothetical lipoprotein YmcA precursor SW:YMCA_ECOLI (P75882) (698 aa) fasta scores: E(): 0, 63.6% id in 698 aa. Contains a probable N-terminal signal sequence. (698 aa)
STY4428Similar to Salmonella typhimurium maltose operon periplasmic protein precursor MalM SW:MALM_SALTY (P26478) (305 aa) fasta scores: E(): 0, 99.3% id in 305 aa and to Escherichia coli maltose operon periplasmic protein precursor MalM SW:MALM_ECOLI (P03841) (306 aa) fasta scores: E(): 0, 90.8% id in 306 aa. Contains N-terminal signal sequence, probable secreted protein. (305 aa)
aphAClass B acid phosphatase precursor; Dephosphorylates several organic phosphate monoesters including monophosphate nucleotides (NMPs), coenzyme A (CoA), nicotinamide adenine dinucleotide phosphate (NADP), flavin mononucleotide (FMN) and phosphorylated 5-6 carbon sugars in vitro. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity). (237 aa)
STY4475Cytochrome c552 precursor; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (478 aa)
STY4476Similar to Escherichia coli cytochrome c-type protein NrfB precursor SW:NRFB_ECOLI (P32707) (188 aa) fasta scores: E(): 0, 88.3% id in 188 aa and to Haemophilus influenzae cytochrome c-type protein NrfB precursor HI1068 SW:NRFB_HAEIN (P45016) (226 aa) fasta scores: E(): 6.6e-24, 45.1% id in 153 aa. (188 aa)
STY4477Cytochrome c-type biogenesis protein; Similar to Escherichia coli NrfC protein SW:NRFC_ECOLI (P32708) (223 aa) fasta scores: E(): 0, 90.6% id in 223 aa, and to Haemophilus influenzae NrfC protein homolog HI1067 SW:NRFC_HAEIN (P45015) (225 aa) fasta scores: E(): 0, 61.6% id in 219 aa. Contains N-terminal signal sequence, probable secreted protein. (223 aa)
phoNSimilar to Salmonella typhimurium nonspecific acid phosphatase precursor phoN SW:PHON_SALTY (P26976) (250 aa) fasta scores: E(): 0, 94.8% id in 250 aa. (250 aa)
artJSimilar to Escherichia coli arginine-binding periplasmic protein 2 precursor artJ SW:ARTJ_ECOLI (P30860) (243 aa) fasta scores: E(): 0, 57.1% id in 238 aa and to Haemophilus influenzae arginine-binding periplasmic protein precursor artI or HI1179 SW:ARTI_HAEIN (P45091) (239 aa) fasta scores: E(): 0, 39.2% id in 240 aa; Belongs to the bacterial solute-binding protein 3 family. (239 aa)
cpdBSimilar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor cpdB SW:CN16_ECOLI (P08331) (647 aa) fasta scores: E(): 0, 90.3% id in 647 aa; Belongs to the 5'-nucleotidase family. (647 aa)
sefBSimilar to Salmonella enteritidis chaperone protein SefB precursor SW:SEFB_SALEN (P33387) (246 aa) fasta scores: E(): 0, 99.2% id in 246 aa, and to Yersinia pestis, and Yersinia pseudotuberculosis chaperone protein PsaB precursor SW:PSAB_YERPE (P31523) (273 aa) fasta scores: E(): 4e-25, 33.5% id in 257 aa, and to Escherichia coli chaperone protein AggD precursor SW:AGGD_ECOLI (P46004) (252 aa) fasta scores: E(): 2.1e-23, 33.5% id in 209 aa. CDS DNA has a low GC content, 28.81%. (250 aa)
mdoBPutative phosphoglycerol transferase; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa)
STY4911Putative periplasmic protein; Probable secreted protein. Similar to Escherichia coli osmotically inducible protein y precursor. OsmY SW:OSMY_ECOLI () (201 aa) fasta scores: E(): 0, 89.3% id in 205 aa, and to Escherichia coli hypothetical 20.0 kDa protein in agaI-mtr intergenic region precursor YraP SW:YRAP_ECOLI (P45467) (191 aa) fasta scores: E(): 0.59, 32.6% id in 175 aa. (205 aa)
sltSimilar to Escherichia coli soluble lytic murein transglycosylase precursor slt or sltY SW:SLT_ECOLI (P03810; P76820) (645 aa) fasta scores: E(): 0, 91.2% id in 627 aa. (627 aa)
sthBSimilar to Escherichia coli chaperone protein FimC SW:FIMC_ECOLI (P31697; P71220) (241 aa) fasta scores: E(): 6.3e-23, 32.6% id in 218 aa, and to Proteus mirabilis type 1 fimbrial chaperone AtfB TR:P72210 (EMBL:Z78535) (225 aa) fasta scores: E(): 7.1e-24, 33.0% id in 221 aa, and to Salmonella typhi FinC gene finC TR:Q56085 (EMBL:X74602) (237 aa) fasta scores: E(): 5.3e-23, 33.0% id in 215 aa. (227 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.