STRINGSTRING
trpS2 trpS2 STY0055 STY0055 STY0699 STY0699 STY0724 STY0724 STY1673 STY1673 STY2117 STY2117 metG metG STY2654 STY2654 trpS trpS valS valS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
trpS2Similar to Clostridium longisporum tryptophanyl-tRNA synthetase TrpS or TrsA SW:SYW_CLOLO (Q46127) (341 aa) fasta scores: E(): 0, 54.8% id in 330 aa, and to Thermotoga maritima tryptophanyl-tRNA synthetase TrpS SW:SYW_THEMA (Q9WYW2) (328 aa) fasta scores: E(): 0, 36.5% id in 329 aa. Note that the E.coli trpS ortholog is STY4315; Belongs to the class-I aminoacyl-tRNA synthetase family. (337 aa)
STY0055isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (944 aa)
STY0699leucyl-tRNA synthetase; Orthologue of E. coli leuS (SYL_ECOLI); Fasta hit to SYL_ECOLI (860 aa), 95% identity in 860 aa overlap; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa)
STY0724glutaminyl-tRNA synthetase; Orthologue of E. coli glnS (SYQ_ECOLI); Fasta hit to SYQ_ECOLI (553 aa), 96% identity in 554 aa overlap. (555 aa)
STY1673tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa)
STY2117arginyl-tRNA synthetase; Orthologue of E. coli argS (SYR_ECOLI); Fasta hit to SYR_ECOLI (577 aa), 95% identity in 577 aa overlap. (577 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (677 aa)
STY2654glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (474 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (951 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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