(5 nodes) Signal transduction histidine kinase, phosphotransfer (Hpt) domain network (Salmonella enterica Typhi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STY3951	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap. (911 aa)
	STY3096	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap. (918 aa)
	STY3507	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap. (778 aa)
	STY2494	Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (889 aa)
	STY2130	Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap. (671 aa)

Your Current Organism:

Salmonella enterica Typhi

NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
STY2130	STY3096	gene:17586037	gene:17586982	Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap.	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	0.913
STY2130	STY3507	gene:17586037	gene:17587358	Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap.	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	0.846
STY2130	STY3951	gene:17586037	gene:17587811	Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap.	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	0.813
STY2494	STY3096	gene:17586397	gene:17586982	Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	0.978
STY2494	STY3507	gene:17586397	gene:17587358	Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	0.983
STY2494	STY3951	gene:17586397	gene:17587811	Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	0.948
STY3096	STY2130	gene:17586982	gene:17586037	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap.	0.913
STY3096	STY2494	gene:17586982	gene:17586397	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.	0.978
STY3096	STY3507	gene:17586982	gene:17587358	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	0.998
STY3096	STY3951	gene:17586982	gene:17587811	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	0.994
STY3507	STY2130	gene:17587358	gene:17586037	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap.	0.846
STY3507	STY2494	gene:17587358	gene:17586397	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.	0.983
STY3507	STY3096	gene:17587358	gene:17586982	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	0.998
STY3507	STY3951	gene:17587358	gene:17587811	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	0.996
STY3951	STY2130	gene:17587811	gene:17586037	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap.	0.813
STY3951	STY2494	gene:17587811	gene:17586397	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.	0.948
STY3951	STY3096	gene:17587811	gene:17586982	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap.	0.994
STY3951	STY3507	gene:17587811	gene:17587358	Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap.	Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap.	0.996

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