STRINGSTRING
sfbB sfbB STY0634 STY0634 STY0697 STY0697 STY0703 STY0703 STY0707 STY0707 STY0715 STY0715 STY0744 STY0744 STY0764 STY0764 STY0803 STY0803 STY0811 STY0811 STY0816 STY0816 STY0830 STY0830 STY0831 STY0831 ybhF ybhF STY0855 STY0855 STY0866 STY0866 ybiT ybiT STY0887 STY0887 STY0911 STY0911 STY0924 STY0924 STY0935 STY0935 ybjZ ybjZ STY0943 STY0943 STY0954 STY0954 STY0955 STY0955 STY0958 STY0958 STY0960 STY0960 STY0980 STY0980 STY0985 STY0985 lpxK lpxK mukB mukB STY1023 STY1023 STY1047 STY1047 STY1083 STY1083 STY1089 STY1089 STY1092 STY1092 STY1097 STY1097 STY1162 STY1162 STY1239 STY1239 STY1240 STY1240 STY1256 STY1256 STY1258 STY1258 STY1266 STY1266 STY1301 STY1301 STY1308 STY1308 STY1309 STY1309 STY1332 STY1332 STY1355 STY1355 STY1356 STY1356 STY1370 STY1370 STY1378 STY1378 STY1428 STY1428 STY1436 STY1436 STY1573 STY1573 STY1575 STY1575 STY1615 STY1615 ssaN ssaN STY1752 STY1752 STY1768 STY1768 STY1831 STY1831 STY1861 STY1861 STY1862 STY1862 STY1910 STY1910 STY1945 STY1945 STY1951 STY1951 STY2040 STY2040 STY2062 STY2062 STY2100 STY2100 STY2102 STY2102 STY2159 STY2159 STY2180 STY2180 STY2221 STY2221 cbiP cbiP cbiO cbiO cbiA cbiA pduV pduV wzc wzc STY2335 STY2335 STY2383 STY2383 STY2393 STY2393 STY2448 STY2448 STY2455 STY2455 STY2460 STY2460 ccmA1 ccmA1 STY2489 STY2489 STY2568 STY2568 STY2581 STY2581 STY2591 STY2591 pgtA pgtA STY2678 STY2678 STY2705 STY2705 STY2723 STY2723 STY2737 STY2737 STY2764 STY2764 STY2809 STY2809 STY2826 STY2826 STY2829 STY2829 STY2836 STY2836 STY2849 STY2849 STY2864 STY2864 STY2870 STY2870 STY2877 STY2877 iroC iroC STY2950 STY2950 STY2961 STY2961 STY2977 STY2977 STY2981 STY2981 sitB sitB spaI spaI STY3033 STY3033 cysC cysC cysN cysN STY3071 STY3071 STY3082 STY3082 recD recD recB recB recC recC STY3232 STY3232 STY3233 STY3233 pilT pilT STY3461 STY3461 STY3467 STY3467 STY3474 STY3474 STY3480 STY3480 STY3492 STY3492 STY3498 STY3498 STY3502 STY3502 STY3526 STY3526 recQ recQ STY3608 STY3608 STY3638 STY3638 rhlB rhlB STY3642 STY3642 STY3675 STY3675 STY3711 STY3711 tufB tufB STY3740 STY3740 STY3775 STY3775 STY3779 STY3779 STY3796 STY3796 STY3871 STY3871 STY3876 STY3876 STY3880 STY3880 STY3887 STY3887 STY3896 STY3896 STY3899 STY3899 STY3911 STY3911 STY3913 STY3913 STY3929 STY3929 STY3937 STY3937 STY3940 STY3940 STY3942 STY3942 STY4048 STY4048 STY4052 STY4052 STY4114 STY4114 STY4171 STY4171 STY4172 STY4172 yhjQ yhjQ STY4224 STY4224 ftsY ftsY ftsE ftsE STY4251 STY4251 STY4252 STY4252 STY4257 STY4257 gntK gntK STY4281 STY4281 feoB feoB aroK aroK prkB prkB yheS yheS fusA fusA STY4426 STY4426 dnaB dnaB uvrA uvrA STY4460 STY4460 STY4521 STY4521 STY4522 STY4522 pilQ pilQ STY4562 STY4562 STY4573 STY4573 STY4627 STY4627 vexC vexC STY4664 STY4664 STY4671 STY4671 yjeQ yjeQ yjeE yjeE miaA miaA hflX hflX purA purA STY4832 STY4832 STY4849 STY4849 STY4850 STY4850 STY0214 STY0214 hsdR hsdR STY4888 STY4888 dnaC dnaC STY4910 STY4910 radA radA nadR nadR STY4928 STY4928 STY0111 STY0111 STY0123 STY0123 STY0156 STY0156 STY0162 STY0162 STY0165 STY0165 STY0194 STY0194 STY0219 STY0219 STY0274 STY0274 STY0294 STY0294 prpR prpR STY0553 STY0553 STY0421 STY0421 STY0429 STY0429 phnT phnT STY0491 STY0491 STY0492 STY0492 mdlA mdlA STY0504 STY0504 STY0528 STY0528 STY0532 STY0532 STY0548 STY0548
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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sfbBABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (338 aa)
STY0634Ferric enterobactin transport ATP-binding protein FepC; Fasta hit to SSUB_ECOLI (255 aa), 33% identity in 225 aa overlap; Fasta hit to FHUC_ECOLI (265 aa), 45% identity in 237 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 49% identity in 250 aa overlap; Fasta hit to HISP_ECOLI (257 aa), 31% identity in 229 aa overlap; Fasta hit to PHNC_ECOLI (262 aa), 30% identity in 246 aa overlap; Fasta hit to YECC_ECOLI (250 aa), 31% identity in 225 aa overlap; Fasta hit to YRBF_ECOLI (269 aa), 30% identity in 267 aa overlap; Fasta hit to GLNQ_ECOLI (240 aa), 33% identity in 220 aa overlap; Fasta hi [...] (264 aa)
STY0697DNA polymerase III, delta subunit; Orthologue of E. coli holA (HOLA_ECOLI); Fasta hit to HOLA_ECOLI (343 aa), 90% identity in 343 aa overlap. (343 aa)
STY0703Similar to Bacillus subtilis putative sigma L-dependent transcriptional regulator in mmge-bfmbaa intergenic region yqiR SW:YQIR_BACSU (P54529) (692 aa) fasta scores: E(): 0, 36.5% id in 444 aa, and to Escherichia coli acetoacetate metabolism regulatory protein atoc SW:ATOC_ECOLI () (461 aa) fasta scores: E(): 0, 38.5% id in 358 aa; Paralogue of E. coli YGEV_ECOLI; Fasta hit to YGEV_ECOLI (592 aa), 31% identity in 525 aa overlap. (642 aa)
STY0707Glutamate/aspartate transport ATP-binding protein GltL; Fasta hit to ARTP_ECOLI (242 aa), 43% identity in 242 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 34% identity in 224 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 39% identity in 217 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 31% identity in 222 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 37% identity in 218 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 31% identity in 228 aa overlap; Fasta hit to PHNK_ECOLI (252 aa), 31% identity in 248 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 31% identity in 243 aa overlap; Fasta hi [...] (241 aa)
STY0715PhoH-like ATP-binding protein; Orthologue of E. coli PHOL_ECOLI; Fasta hit to PHOL_ECOLI (359 aa), 96% identity in 359 aa overlap. (361 aa)
STY0744Sensor protein KdpD; Orthologue of E. coli kdpD (KDPD_ECOLI); Fasta hit to KDPD_ECOLI (894 aa), 89% identity in 902 aa overlap. (902 aa)
STY0764Putative polysaccharide export ABC transporter ATP-binding protein; Similar to Mycobacterium tuberculosis hypothetical 30.0 kDa protein cy13d12.15 rv3781 or mtcy13d12.15 TR:P72047 (EMBL:Z80343) (273 aa) fasta scores: E(): 0, 43.8% id in 233 aa, and to Yersinia enterocolitica O-antigen export system ATP-binding protein RfbE rfbE SW:RFBE_YEREN (Q56903) (239 aa) fasta scores: E(): 0, 45.3% id in 225 aa. (236 aa)
STY0803Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC fhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 6.7e-25, 35.7% id in 244 aa, and to Erwinia chrysanthemi achromobactin transport ATP-binding protein CbrD cbrD SW:CBRD_ERWCH (Q47087) (273 aa) fasta scores: E(): 2.9e-24, 35.7% id in 244 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein FepC fepC SW:FEPC_ECOLI (P23878; P75724; P77096) (271 aa) fasta scores: E(): 3e-22, 34.2% id in 240 aa; Fasta hit to YCFV_ECOLI (233 aa), 31% identity in 227 aa overlap; Fasta hit to ZNUC_ECOLI ( [...] (258 aa)
STY0811Putative molybdenum transport ATP-binding protein ModF (photorepair protein PhrA); Orthologue of E. coli modF (MODF_ECOLI); Fasta hit to MODF_ECOLI (490 aa), 89% identity in 485 aa overlap. (491 aa)
STY0816Molybdenum transport ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa)
STY0830Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (228 aa)
STY0831Excision nuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissoc [...] (673 aa)
ybhFSimilar to Escherichia coli hypothetical ABC transporter ATP-binding protein YbhF ybhF SW:YBHF_ECOLI (P75776) (578 aa) fasta scores: E(): 0, 91.3% id in 578 aa, and to Rhizobium sp nodulation ATP-binding protein i nodi or y4hF SW:NODI_RHISN (P55476) (343 aa) fasta scores: E(): 9.4e-25, 37.5% id in 232 aa. (578 aa)
STY0855Putative ATP-dependent RNA helicase rhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (455 aa)
STY0866Glutamine transport ATP-binding protein GlnQ; Fasta hit to ARTP_ECOLI (242 aa), 44% identity in 241 aa overlap; Fasta hit to FEPC_ECOLI (271 aa), 34% identity in 220 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 40% identity in 209 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 39% identity in 226 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 36% identity in 224 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 31% identity in 226 aa overlap; Fasta hit to PHNK_ECOLI (252 aa), 30% identity in 247 aa overlap; Fasta hit to GLTL_ECOLI (241 aa), 53% identity in 239 aa overlap; Fasta hit to TAUB_ [...] (240 aa)
ybiTSimilar to Escherichia coli hypothetical ABC transporter ATP-binding protein YbiT ybiT SW:YBIT_ECOLI (P75790) (530 aa) fasta scores: E(): 0, 96.8% id in 530 aa, and to Haemophilus influenzae hypothetical ABC transporter ATP-binding protein Hi0658 hi0658 SW:YHES_HAEIN (P44808) (638 aa) fasta scores: E(): 0, 32.3% id in 530 aa; Fasta hit to YHES_ECOLI (637 aa), 32% identity in 527 aa overlap; Fasta hit to UUP_ECOLI (635 aa), 33% identity in 526 aa overlap; Orthologue of E. coli YBIT_ECOLI; Fasta hit to YBIT_ECOLI (530 aa), 97% identity in 530 aa overlap. (531 aa)
STY0887Hypothetical ABC transporter ATP-binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family. (623 aa)
STY0911Putrescine transport ATP-binding protein PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
STY0924Arginine transport ATP-binding protein ArtP; Fasta hit to YCFV_ECOLI (233 aa), 35% identity in 205 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 37% identity in 216 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 30% identity in 235 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 36% identity in 213 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 34% identity in 226 aa overlap; Fasta hit to PHNK_ECOLI (252 aa), 31% identity in 226 aa overlap; Fasta hit to GLTL_ECOLI (241 aa), 45% identity in 241 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 36% identity in 216 aa overlap; Fasta hit to HISP_E [...] (242 aa)
STY0935Conserved hypothetical protein; Orthologue of E. coli YBJD_ECOLI; Fasta hit to YBJD_ECOLI (552 aa), 90% identity in 552 aa overlap. (552 aa)
ybjZConserved hypothetical ABC transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa)
STY0943ATP-dependent Clp protease ATP-binding subunit ClpA; Fasta hit to CLPB_ECOLI (857 aa), 36% identity in 863 aa overlap; Orthologue of E. coli clpA (CLPA_ECOLI); Fasta hit to CLPA_ECOLI (758 aa), 97% identity in 758 aa overlap; Belongs to the ClpA/ClpB family. (758 aa)
STY0954Transport ATP-binding protein CydC; Orthologue of E. coli cydC (CYDC_ECOLI); Fasta hit to CYDC_ECOLI (573 aa), 86% identity in 573 aa overlap. (573 aa)
STY0955Transport ATP-binding protein CydD; Orthologue of E. coli cydD (CYDD_ECOLI); Fasta hit to CYDD_ECOLI (588 aa), 91% identity in 588 aa overlap. (588 aa)
STY0958Cell division protein FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA [...] (1343 aa)
STY0960Conserevd hypothetical protein; Orthologue of E. coli ycaJ (YCAJ_ECOLI); Fasta hit to YCAJ_ECOLI (447 aa), 97% identity in 447 aa overlap. (447 aa)
STY0980Cytidylate kinase; Orthologue of E. coli cmk (KCY_ECOLI); Fasta hit to KCY_ECOLI (227 aa), 98% identity in 227 aa overlap. (227 aa)
STY0985Probable transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (325 aa)
mukBCell division protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1488 aa)
STY1023Similar to several including: Escherichia coli DNA replication protein DnaC or DnaD SW:DNAC_ECOLI (P07905) (245 aa) fasta scores: E(): 0, 48.8% id in 244 aa, Streptococcus thermophilus bacteriophage 7201 Orf5 TR:AAF26604 (EMBL:AF145054) (260 aa) fasta scores: E(): 5.1e-06, 23.3% id in 193 aa and Salmonella typhimurium hypothetical 27.6 kda protein TR:O84893 (EMBL:AF001386) fasta scores: E(): 0, 100.0% id in 249 aa; Fasta hit to DNAC_ECOLI (245 aa), 49% identity in 244 aa overlap; Paralogue of E. coli P77546; Fasta hit to P77546 (248 aa), 55% identity in 249 aa overlap. (249 aa)
STY1047Similar to Bacteriophage SPP1 terminase large subunit 2 SW:TERL_BPSPP (P54308) fasta scores: E(): 6.4e-05, 26.7% id in 322 aa, Haemophilus influenzae hypothetical protein HI1410 SW:YE10_HAEIN (P44184) fasta scores: E(): 0, 45.1% id in 397 aa and to Bacteriophage APSE-1 p18 TR:Q9T1T0 (EMBL:AF157835) fasta scores: E(): 1.9e-24, 34.1% id in 455 aa, and to. (467 aa)
STY1083ABC transporter ATP-binding protein; Fasta hit to YBIT_ECOLI (530 aa), 32% identity in 526 aa overlap; Fasta hit to YJJK_ECOLI (554 aa), 34% identity in 524 aa overlap; Orthologue of E. coli UUP_ECOLI; Fasta hit to UUP_ECOLI (635 aa), 94% identity in 634 aa overlap. (635 aa)
STY1089Conserved hypothetical protein; Similar to Haemophilus influenzae protease la homolog LON-B OR HI1324 SW:LONH_HAEIN (P43865) fasta scores: E(): 0, 41.1% id in 584 aa; Orthologue of E. coli P75867; Fasta hit to P75867 (586 aa), 86% identity in 586 aa overlap. (586 aa)
STY1092Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (169 aa)
STY1097Helicase IV (75 kD helicase); Orthologue of E. coli helD (HELD_ECOLI); Fasta hit to HELD_ECOLI (684 aa), 84% identity in 684 aa overlap. (684 aa)
STY1162PhoH protein (phosphate starvation-inducible protein PsiH); Orthologue of E. coli phoH (PHOH_ECOLI); Fasta hit to PHOH_ECOLI (354 aa), 93% identity in 284 aa overlap. (284 aa)
STY1239Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa)
STY1240DNA polymerase III, delta' subunit; Orthologue of E. coli holB (HOLB_ECOLI); Fasta hit to HOLB_ECOLI (334 aa), 79% identity in 334 aa overlap. (334 aa)
STY1256Transcription-repair coupling factor (TrcF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1148 aa)
STY1258ABC transporter ATP-binding subunit; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa)
STY1266Spermidine/putrescine transport ATP-binding protein PotA (ABC superfamily); Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
STY1301Thymidine kinase; Orthologue of E. coli tdk (KITH_ECOLI); Fasta hit to KITH_ECOLI (205 aa), 93% identity in 204 aa overlap. (205 aa)
STY1308Oligopeptide transport ATP-binding protein OppD; Fasta hit to DPPF_ECOLI (334 aa), 37% identity in 336 aa overlap; Fasta hit to SAPD_ECOLI (330 aa), 39% identity in 325 aa overlap; Fasta hit to YDDO_ECOLI (308 aa), 35% identity in 326 aa overlap; Fasta hit to YDDP_ECOLI (328 aa), 45% identity in 327 aa overlap; Fasta hit to OPPF_ECOLI (334 aa), 43% identity in 329 aa overlap; Fasta hit to DPPD_ECOLI (327 aa), 45% identity in 319 aa overlap; Orthologue of E. coli oppD (OPPD_ECOLI); Fasta hit to OPPD_ECOLI (337 aa), 92% identity in 337 aa overlap; Belongs to the ABC transporter superfamily. (335 aa)
STY1309Oligopeptide transport ATP-binding protein OppF; Fasta hit to DPPF_ECOLI (334 aa), 50% identity in 323 aa overlap; Fasta hit to OPPD_ECOLI (337 aa), 40% identity in 337 aa overlap; Fasta hit to SAPD_ECOLI (330 aa), 35% identity in 329 aa overlap; Fasta hit to YDDO_ECOLI (308 aa), 43% identity in 301 aa overlap; Fasta hit to YDDP_ECOLI (328 aa), 36% identity in 316 aa overlap; Fasta hit to DPPD_ECOLI (327 aa), 39% identity in 316 aa overlap; Orthologue of E. coli oppF (OPPF_ECOLI); Fasta hit to OPPF_ECOLI (334 aa), 95% identity in 334 aa overlap; Belongs to the ABC transporter superfamily. (334 aa)
STY1332COB(I) alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (196 aa)
STY1355Peptide transport system ATP-binding protein SapF; Fasta hit to YCFV_ECOLI (233 aa), 32% identity in 232 aa overlap; Fasta hit to YDDO_ECOLI (308 aa), 38% identity in 254 aa overlap; Fasta hit to YDDP_ECOLI (328 aa), 31% identity in 263 aa overlap; Fasta hit to YECC_ECOLI (250 aa), 30% identity in 257 aa overlap; Fasta hit to NIKE_ECOLI (268 aa), 33% identity in 234 aa overlap; Orthologue of E. coli sapF (SAPF_ECOLI); Fasta hit to SAPF_ECOLI (268 aa), 97% identity in 268 aa overlap. (268 aa)
STY1356Peptide transport system ATP-binding protein SapD; Fasta hit to OPPD_ECOLI (337 aa), 37% identity in 324 aa overlap; Fasta hit to YDDO_ECOLI (308 aa), 31% identity in 320 aa overlap; Fasta hit to YDDP_ECOLI (328 aa), 38% identity in 328 aa overlap; Fasta hit to OPPF_ECOLI (334 aa), 34% identity in 329 aa overlap; Fasta hit to DPPD_ECOLI (327 aa), 44% identity in 328 aa overlap; Orthologue of E. coli sapD (SAPD_ECOLI); Fasta hit to SAPD_ECOLI (330 aa), 96% identity in 330 aa overlap; Belongs to the ABC transporter superfamily. (330 aa)
STY1370Psp operon transcriptional activator PspF; Orthologue of E. coli pspF (PSPF_ECOLI); Fasta hit to PSPF_ECOLI (325 aa), 87% identity in 326 aa overlap. (326 aa)
STY1378Transcriptional regulatory protein TyrR; Involved in transcriptional regulation of aromatic amino acid biosynthesis and transport. Modulates the expression of at least 8 unlinked operons. Seven of these operons are regulated in response to changes in the concentration of the three aromatic amino acids (phenylalanine, tyrosine and tryptophan). These amino acids are suggested to act as co-effectors which bind to the TyrR protein to form an active regulatory protein. In most cases TyrR causes negative regulation, but positive effects on the tyrP gene have been observed at high phenylalani [...] (513 aa)
STY1428ATP-dependent helicase HrpA; Orthologue of E. coli hrpA (HRPA_ECOLI); Fasta hit to HRPA_ECOLI (1281 aa), 96% identity in 1280 aa overlap. (1300 aa)
STY1436ABC transporter ATP-binding subunit; Fasta hit to ARTP_ECOLI (242 aa), 37% identity in 222 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 33% identity in 224 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 37% identity in 214 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 34% identity in 218 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 35% identity in 206 aa overlap; Fasta hit to GLTL_ECOLI (241 aa), 42% identity in 225 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 34% identity in 216 aa overlap; Fasta hit to HISP_ECOLI (257 aa), 39% identity in 247 aa overlap; Fasta hit to FTSE_ECOLI (22 [...] (243 aa)
STY1573Putative ABC transporter ATP/GTP-binding protein; Similar to Streptomyces coelicolor ProvL TR:Q9X4J1 (EMBL:AF112365) (429 aa) fasta scores: E(): 0, 46.6% id in 367 aa, and to Bacillus subtilis choline transport ATP-binding protein ProV SW:OPBA_BACSU (Q45460; O34332) (381 aa) fasta scores: E(): 0, 45.9% id in 379 aa; Fasta hit to POTA_ECOLI (378 aa), 34% identity in 320 aa overlap; Paralogue of E. coli proV (PROV_ECOLI); Fasta hit to PROV_ECOLI (400 aa), 34% identity in 371 aa overlap. (382 aa)
STY1575Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (231 aa)
STY1615Similar to Haemophilus influenzae hypothetical protein Hi1500 SW:YF00_HAEIN (P44224) (508 aa) fasta scores: E(): 0, 48.6% id in 477 aa. (531 aa)
ssaNPutative type III secretion ATP synthase; Similar to Salmonella typhimurium probable secretion system apparatus ATP synthase SsaN SW:SSAN_SALTY (P74857) (433 aa) fasta scores: E(): 0, 99.3% id in 433 aa, and to Yersinia enterocolitica probable ATP synthase YscN SW:YSCN_YEREN (P40290) (439 aa) fasta scores: E(): 0, 56.6% id in 401 aa; Paralogue of E. coli fliI (FLII_ECOLI); Fasta hit to FLII_ECOLI (457 aa), 44% identity in 427 aa overlap. (433 aa)
STY1752Putative ABC transport ATP-binding subunit; Orthologue of E. coli YNHD_ECOLI; Fasta hit to YNHD_ECOLI (248 aa), 93% identity in 248 aa overlap. (248 aa)
STY1768Vitamin B12 ABC transport ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa)
STY1831Similar to Escherichia coli hypothetical 74.5 kDa protein in gapa-rnd intergenic region yeaG SW:YEAG_ECOLI (P77391; O07963) (644 aa) fasta scores: E(): 0, 98.1% id in 644 aa, and to Bacillus subtilis PrkA protein prkA SW:PRKA_BACSU (P39134) (631 aa) fasta scores: E(): 0, 32.7% id in 637 aa. (644 aa)
STY1861Putative ABC transport ATP-binding subunit; Similar to Salmonella typhimurium putative ATPase oxd-6E TR:O34160 (EMBL:U94729) (196 aa) fasta scores: E(): 0, 97.4% id in 196 aa, and to Streptococcus pyogenes ATPase protein DppE dppE TR:Q9ZAS2 (EMBL:U78968) (208 aa) fasta scores: E(): 1.5e-26, 40.9% id in 181 aa, and to Escherichia coli hypothetical ABC transporter ATP-binding protein yddo. hypothetical abc transporter ATP-binding protein yddo SW:YDDO_ECOLI () (308 aa) fasta scores: E(): 8.4e-09, 31.5% id in 184 aa. (196 aa)
STY1862Putative ABC transport ATP-binding protein; Similar to Salmonella typhimurium putative ATPase oxd-6D TR:O34159 (EMBL:U94729) (265 aa) fasta scores: E(): 0, 98.9% id in 265 aa, and to Streptococcus pyogenes ATPase protein DppD dppD TR:Q9ZAS3 (EMBL:U78968) (267 aa) fasta scores: E(): 2.7e-20, 29.1% id in 258 aa. (265 aa)
STY1910Putative ATP/GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
STY1945Septum site determining protein; Orthologue of E. coli minD (MIND_ECOLI); Fasta hit to MIND_ECOLI (269 aa), 97% identity in 269 aa overlap. (270 aa)
STY1951Similar to Escherichia coli probable ATP-dependent helicase YoaA SW:YOAA_ECOLI (P76257) (636 aa) fasta scores: E(): 0, 95.1% id in 635 aa, and to Haemophilus influenzae probable ATP-dependent helicase Hi0387 SW:YOAA_HAEIN (P44680) (640 aa) fasta scores: E(): 0, 62.4% id in 633 aa, and to Streptomyces coelicolor putative ATP-dependent helicase SC4H2.23 TR:O69978 (EMBL:AL022268) (664 aa) fasta scores: E(): 2.1e-32, 33.6% id in 660 aa. (636 aa)
STY2040Similar to many bacteriophage putative proteins e.g. Bacteriophage APSE-1 p18 TR:Q9T1T0 (EMBL:AF157835) (469 aa) fasta scores: E(): 7.6e-25, 34.2% id in 462 aa. Similar to Haemophilus influenzae hypothetical protein HI1410 SW:YE10_HAEIN (P44184) (394 aa) fasta scores: E(): 0, 44.9% id in 396 aa. (467 aa)
STY2062Similar to several including: Escherichia coli DNA replication protein DnaC or dnaD SW:DNAC_ECOLI (P07905) (245 aa) fasta scores: E(): 0, 49.2% id in 242 aa, Streptococcus thermophilus bacteriophage 7201 Orf5 TR:AAF26604 (EMBL:AF145054) (260 aa) fasta scores: E(): 6.3e-06, 23.3% id in 189 aa and Salmonella typhimurium hypothetical protein TR:O84893 (EMBL:AF001386) (249 aa) fasta scores: E(): 0, 56.6% id in 249 aa; Fasta hit to DNAC_ECOLI (245 aa), 49% identity in 242 aa overlap; Orthologue of E. coli P77546; Fasta hit to P77546 (248 aa), 96% identity in 248 aa overlap. (248 aa)
STY2100High-affinity zinc uptake system ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa)
STY2102Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa)
STY2159Similar to many ABC-transporter ATP-binding proteins, mostly of amino-acid (or related) transport systeams e.g. Agrobacterium tumefaciens octopine permease ATP-binding protein P SW:OCCP_AGRT6 (P35117) (262 aa) fasta scores: E(): 0, 52.6% id in 249 aa; Fasta hit to ARTP_ECOLI (242 aa), 48% identity in 238 aa overlap; Fasta hit to FEPC_ECOLI (271 aa), 30% identity in 222 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 36% identity in 229 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 37% identity in 217 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 38% identity in 229 aa overlap; Fasta hit [...] (250 aa)
STY2180Similar to Salmonella typhimurium flagellum-specific ATP synthase fliI or flaC SW:FLII_SALTY (P26465) (456 aa) fasta scores: E(): 0, 99.6% id in 456 aa; Fasta hit to ATPB_ECOLI (459 aa), 30% identity in 416 aa overlap; Orthologue of E. coli fliI (FLII_ECOLI); Fasta hit to FLII_ECOLI (457 aa), 93% identity in 456 aa overlap. (456 aa)
STY2221Cobinamide kinase and guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (181 aa)
cbiPPutative cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. (506 aa)
cbiOPutative cobalt transport ATP-binding protein CbiO; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. Presumably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family. (271 aa)
cbiACobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (474 aa)
pduVSimilar to Salmonella typhimurium propanediol utilization protein pduV SW:PDUV_SALTY (Q9XDM6) (150 aa) fasta scores: E(): 0, 97.3% id in 150 aa and Salmonella typhimurium ethanolamine utilization protein eutP SW:EUTP_SALTY (Q9ZFV6) (159 aa) fasta scores: E(): 2.7e-08, 32.2% id in 143 aa; Belongs to the EutP/PduV family. (150 aa)
wzcPutative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family. (719 aa)
STY2335Uridine kinase; Orthologue of E. coli udk (URK_ECOLI); Fasta hit to URK_ECOLI (213 aa), 96% identity in 213 aa overlap. (213 aa)
STY2383Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa)
STY2393ABC transporter ATP-binding protein; Similar to e.g. Bacillus subtilis choline transport ATP-binding protein opuBA or proV SW:OPBA_BACSU (Q45460; O34332) (381 aa) fasta scores: E(): 0, 45.3% id in 296 aa; Fasta hit to AFUC_ECOLI (348 aa), 32% identity in 297 aa overlap; Orthologue of E. coli yehX (YEHX_ECOLI); Fasta hit to YEHX_ECOLI (308 aa), 88% identity in 307 aa overlap. (315 aa)
STY2448Conserved hypothetical protein; Orthologue of E. coli yeiR (YEIR_ECOLI); Fasta hit to YEIR_ECOLI (328 aa), 87% identity in 328 aa overlap. (328 aa)
STY2455Putative ABC-transporter ATP-binding protein; Fasta hit to YLIA_ECOLI (612 aa), 49% identity in 555 aa overlap; Orthologue of E. coli yejF (YEJF_ECOLI); Fasta hit to YEJF_ECOLI (529 aa), 87% identity in 529 aa overlap; Belongs to the ABC transporter superfamily. (529 aa)
STY2460Putative helicase; Orthologue of E. coli yejH (YEJH_ECOLI); Fasta hit to YEJH_ECOLI (586 aa), 95% identity in 586 aa overlap. (586 aa)
ccmA1Heme exporter protein A1; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa)
STY2489Putative ABC transporter ATP-binding protein; Orthologue of E. coli yojI (YOJI_ECOLI); Fasta hit to YOJI_ECOLI (547 aa), 91% identity in 547 aa overlap. Contains hydrophobic, probable membrane-spanning regions. (547 aa)
STY2568Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa)
STY2581Similar to Salmonella typhimurium histidine transport ATP-binding protein HisP hisP SW:HISP_SALTY (P02915) (258 aa) fasta scores: E(): 0, 98.8% id in 258 aa; Fasta hit to ARTP_ECOLI (242 aa), 44% identity in 238 aa overlap; Fasta hit to FEPC_ECOLI (271 aa), 31% identity in 229 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 36% identity in 219 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 35% identity in 238 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 36% identity in 239 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 31% identity in 238 aa overlap; Fasta hit to PHNK_ECOLI (252 aa), 30% [...] (258 aa)
STY2591Similar to many transcriptional regulators e.g. Bacillus subtilis arginine utilization regulatory protein RocR rocR SW:ROCR_BACSU (P38022) (461 aa) fasta scores: E(): 0, 36.1% id in 457 aa and Escherichia coli acetoacetate metabolism regulatory protein AtoC atoC SW:ATOC_ECOLI (Q06065) (461 aa) fasta scores: E(): 0, 40.6% id in 345 aa. (475 aa)
pgtASimilar to Salmonella typhimurium phosphoglycerate transport system transcriptional regulatory protein PgtA pgtA SW:PGTA_SALTY (P06184) (415 aa) fasta scores: E(): 0, 98.1% id in 415 aa. (415 aa)
STY2678Sulphate transport ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (364 aa)
STY2705Similar to Salmonella typhimurium LT2 ethanolamine utilization protein EutP eutP SW:EUTP_SALTY (Q9ZFV6) (159 aa) fasta scores: E(): 0, 100.0% id in 159 aa and to Salmonella typhimurium propanediol utilization protein PduV pduV SW:PDUV_SALTY (Q9XDM6) (150 aa) fasta scores: E(): 4.1e-07, 30.1% id in 143 aa; Orthologue of E. coli EUTP_ECOLI; Fasta hit to EUTP_ECOLI (159 aa), 85% identity in 159 aa overlap. (159 aa)
STY2723Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (671 aa)
STY2737Conserved hypothetical protein; Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity); Belongs to the DnaA family. HdA subfamily. (241 aa)
STY2764Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (490 aa)
STY2809Similar to many e.g. Escherichia coli transcriptional regulatory protein HydG hydG SW:HYDG_ECOLI (P14375) (441 aa) fasta scores: E(): 0, 44.6% id in 439 aa and Pseudomonas aeruginosa type 4 fimbriae expression regulatory protein PilR pilR SW:PILR_PSEAE (Q00934) (446 aa) fasta scores: E(): 0, 40.2% id in 443 aa; Fasta hit to HYDG_ECOLI (441 aa), 45% identity in 439 aa overlap; Fasta hit to NTRC_ECOLI (469 aa), 42% identity in 404 aa overlap; Fasta hit to YGAA_ECOLI (529 aa), 37% identity in 449 aa overlap; Fasta hit to ATOC_ECOLI (461 aa), 41% identity in 454 aa overlap; Orthologue of E [...] (445 aa)
STY2826GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa)
STY2829GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa)
STY2836ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (444 aa)
STY2849ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/Clp [...] (857 aa)
STY2864Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (453 aa)
STY2870DNA repair protein; May be involved in recombinational repair of damaged DNA. (553 aa)
STY2877Putative type I secretion protein, ATP-binding protein; Similar to many including: Actinobacillus pleuropneumoniae RTX-I toxin determinant B ApxIB SW:RT1B_ACTPL (P26760) (707 aa) fasta scores: E(): 0, 28.2% id in 698 aa, Actinobacillus actinomycetemcomitans leukotoxin secretion ATP-binding protein LktB SW:HLYB_ACTAC (P23702) (707 aa) fasta scores: E(): 0, 26.7% id in 707 aa and Escherichia coli hemolysin secretion ATP-binding protein HlyB SW:HLYB_ECOLI () (707 aa) fasta scores: E(): 0, 27.1% id in 643 aa. Contains multiple possible membrane spanning hydrophobic domains. (718 aa)
iroCPutative ABC transporter protein; Similar to many e.g. Salmonella typhi AJB70 ATP binding cassette protein iroC TR:P96057 (EMBL:U62129) (1218 aa) fasta scores: E(): 0, 95.3% id in 1223 aa and Mycobacterium tuberculosis putative ABC transporter Rv0194 or MTV033.02 TR:O53645 (EMBL:AL021928) (1194 aa) fasta scores: E(): 0, 37.8% id in 1203 aa. Conatins hydrophobic, probable membrane spanning regions. (1218 aa)
STY2950RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa)
STY2961Putative sigma-54-dependent transriptional regulator; Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54. (506 aa)
STY2977Hydrogenase isoenzymes formation protein HypB; Orthologue of E. coli hypB (HYPB_ECOLI); Fasta hit to HYPB_ECOLI (290 aa), 95% identity in 290 aa overlap. (290 aa)
STY2981Transcriptional activator of the formate hydrogenlyase system; Fasta hit to HYFR_ECOLI (670 aa), 50% identity in 564 aa overlap; Orthologue of E. coli fhlA (FHLA_ECOLI); Fasta hit to FHLA_ECOLI (692 aa), 90% identity in 691 aa overlap. (692 aa)
sitBIron transport protein, ATP-binding component; Similar to Salmonella typhimurium SitB an iron transport protein located on centisome 63 pathogenicity island TR:Q9XCS1 (EMBL:AF128999) (273 aa) fasta scores: E(): 0, 98.9% id in 273 aa, and to Yersinia pestis YfeB TR:Q56953 (EMBL:U50597) (296 aa) fasta scores: E(): 0, 63.2% id in 266 aa; Fasta hit to ZNUC_ECOLI (251 aa), 31% identity in 223 aa overlap; Fasta hit to FHUC_ECOLI (265 aa), 30% identity in 253 aa overlap; Fasta hit to GLTL_ECOLI (241 aa), 30% identity in 232 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 30% identity in 220 aa [...] (273 aa)
spaISecretory apparatus ATP synthase (associated with virulence); Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells (By similarity). (431 aa)
STY3033DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). (855 aa)
cysCAdenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (201 aa)
cysNATP sulfurylase (ATP:sulfate adenyltransferase) subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (479 aa)
STY3071Conserved hypothetical protein; Orthologue of E. coli ygcB (YGCB_ECOLI); Fasta hit to YGCB_ECOLI (888 aa), 35% identity in 738 aa overlap. (735 aa)
STY3082CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
recDExonuclease V alpha-subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Hol [...] (611 aa)
recBExonuclease V subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzym [...] (1181 aa)
recCExonuclease V subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzym [...] (1123 aa)
STY3232Possible ABC-transport protein, ATP-binding component; Similar to Pyrococcus abyssi ABC transporter, ATP-binding protein TR:Q9V1Q4 (EMBL:AJ248284) (280 aa) fasta scores: E(): 1.3e-15, 33.6% id in 223 aa. Note the unusual overlap with the upstream CDS. (227 aa)
STY3233Possible ABC-transport protein, ATP-binding component; Similar to Methanococcus jannaschii cobalt transport ATP-binding protein TR:Q58488 (EMBL:U67551) (279 aa) fasta scores: E(): 9.6e-20, 31.9% id in 210 aa. (218 aa)
pilTType II secretion, ATP-binding, protein; Similar to several PulE/OutE/ExeE/XpsE/XcpR family proteins including: Pseudomonas aeruginosa PilT thought to be involved in pilus retraction and twitching motility SW:PILT_PSEAE (P24559) (344 aa) fasta scores: E(): 0, 45.0% id in 327 aa. Also highly similar to Escherichia coli hypothetical 36.0 kDa protein YggR SW:YGGR_ECOLI (P52052; P76649) (326 aa) fasta scores: E(): 0, 78.8% id in 326 aa; Orthologue of E. coli YGGR_ECOLI; Fasta hit to YGGR_ECOLI (326 aa), 79% identity in 326 aa overlap. (326 aa)
STY3461ATP-dependent RNA helicase (dead-box protein); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (646 aa)
STY3467Protein chain initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (892 aa)
STY3474Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. (644 aa)
STY3480Probable GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (390 aa)
STY3492Possible ABC-transport protein, ATP-binding component; Fasta hit to ARTP_ECOLI (242 aa), 30% identity in 234 aa overlap; Fasta hit to YHBG_ECOLI (240 aa), 33% identity in 228 aa overlap; Fasta hit to GLTL_ECOLI (241 aa), 30% identity in 242 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 31% identity in 228 aa overlap; Fasta hit to YECC_ECOLI (250 aa), 34% identity in 229 aa overlap; Fasta hit to GLNQ_ECOLI (240 aa), 32% identity in 245 aa overlap; Fasta hit to PSTB_ECOLI (257 aa), 31% identity in 256 aa overlap; Orthologue of E. coli YRBF_ECOLI; Fasta hit to YRBF_ECOLI (269 aa), 95% ide [...] (270 aa)
STY3498Probable ABC transport protein, ATP-binding component; Fasta hit to ARTP_ECOLI (242 aa), 30% identity in 212 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 30% identity in 203 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 33% identity in 233 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 35% identity in 229 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 31% identity in 237 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 32% identity in 238 aa overlap; Fasta hit to LIVG_ECOLI (255 aa), 32% identity in 249 aa overlap; Fasta hit to FTSE_ECOLI (222 aa), 30% identity in 216 aa overlap; Fasta hit [...] (241 aa)
STY3502Conserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (284 aa)
STY3526Putative ATP/GTP-binding protein; Reduces the stability of FtsZ polymers in the presence of ATP. (374 aa)
recQSimilar to Escherichia coli ATP-dependent DNA helicase RecQ SW:RECQ_ECOLI (P15043; P76762) (607 aa) fasta scores: E(): 0, 94.6% id in 608 aa. (609 aa)
STY3608DNA helicase II; Fasta hit to REP_ECOLI (673 aa), 38% identity in 666 aa overlap; Orthologue of E. coli uvrD (UVRD_ECOLI); Fasta hit to UVRD_ECOLI (720 aa), 98% identity in 720 aa overlap. (720 aa)
STY3638Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa)
rhlBPutative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (421 aa)
STY3642ATP-dependent DNA helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (674 aa)
STY3675Similar to Bacteriophage P2 terminase, ATPase subunit P SW:VPP_BPP2 (P25479) (590 aa) fasta scores: E(): 0, 63.9% id in 590 aa and to Bacteriophage 186 terminase subunit TR:Q9T0R3 (EMBL:U32222) (589 aa) fasta scores: E(): 0, 63.4% id in 579 aa. (588 aa)
STY3711Transcriptional regulatory protein; Member of the two-component regulatory system ZraS/ZraR. When activated by ZraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon (By similarity). (441 aa)
tufBElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)
STY3740Pantothenate kinase; Orthologue of E. coli coaA (COAA_ECOLI); Fasta hit to COAA_ECOLI (316 aa), 96% identity in 316 aa overlap. (316 aa)
STY3775Primosomal protein replication factor; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa)
STY3779Heat shock protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa)
STY3796Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (By similarity). (511 aa)
STY3871GTP-binding protein; Similar to Escherichia coli GTP-binding protein implicated in virulence in EPEC strains, TypA SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 0, 97.0% id in 591 aa. (607 aa)
STY3876Two-component system, response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa)
STY3880ATP/GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (210 aa)
STY3887Molybdopterin-guanine dinucleotide biosynthesis protein B; Orthologue of E. coli MOBB_ECOLI; Fasta hit to MOBB_ECOLI (174 aa), 78% identity in 167 aa overlap. (171 aa)
STY3896High affinity ribose transport protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
STY3899Conserved hypothetical protein; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (498 aa)
STY3911ATP synthase alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa)
STY3913ATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa)
STY3929Phosphate transport ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa)
STY3937Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (454 aa)
STY3940Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (466 aa)
STY3942recF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity). (357 aa)
STY4048ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa)
STY40525'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)
STY4114Selenocysteine-specific elongation factor; Orthologue of E. coli selB (SELB_ECOLI); Fasta hit to SELB_ECOLI (614 aa), 85% identity in 615 aa overlap. (616 aa)
STY4171Dipeptide transport ATP-binding protein DppD; Fasta hit to OPPD_ECOLI (337 aa), 46% identity in 320 aa overlap; Fasta hit to DPPF_ECOLI (334 aa), 36% identity in 306 aa overlap; Fasta hit to SAPD_ECOLI (330 aa), 44% identity in 330 aa overlap; Fasta hit to YDDO_ECOLI (308 aa), 36% identity in 305 aa overlap; Fasta hit to YDDP_ECOLI (328 aa), 43% identity in 318 aa overlap; Fasta hit to OPPF_ECOLI (334 aa), 38% identity in 317 aa overlap; Orthologue of E. coli dppD (DPPD_ECOLI); Fasta hit to DPPD_ECOLI (327 aa), 95% identity in 327 aa overlap; Belongs to the ABC transporter superfamily. (327 aa)
STY4172Dipeptide transport ATP-binding protein DppF; Fasta hit to OPPD_ECOLI (337 aa), 39% identity in 302 aa overlap; Fasta hit to YDDO_ECOLI (308 aa), 42% identity in 318 aa overlap; Fasta hit to YDDP_ECOLI (328 aa), 34% identity in 333 aa overlap; Fasta hit to OPPF_ECOLI (334 aa), 50% identity in 323 aa overlap; Fasta hit to DPPD_ECOLI (327 aa), 36% identity in 307 aa overlap; Orthologue of E. coli dppF (DPPF_ECOLI); Fasta hit to DPPF_ECOLI (334 aa), 96% identity in 334 aa overlap; Belongs to the ABC transporter superfamily. (337 aa)
yhjQConserved hypothetical protein; Essential for cellulose biosynthesis. May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity); Belongs to the BcsQ family. (250 aa)
STY4224Similar to Escherichia coli hypothetical ABC transporter ATP-binding protein YhiH SW:YHIH_ECOLI (P37624) (894 aa) fasta scores: E(): 0, 89.3% id in 896 aa, and to Escherichia coli hypothetical ABC transporter ATP-binding protein YbhF SW:YBHF_ECOLI (P75776) (578 aa) fasta scores: E(): 0, 35.9% id in 574 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (913 aa)
ftsYCell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (491 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (222 aa)
STY4251High-affinity branched-chain amino acid transport ATP-binding protein; Component of the high-affinity branched-chain amino acid transport system. (255 aa)
STY4252High-affinity branched-chain amino acid transport ATP-binding protein; Component of the high-affinity branched-chain amino acid transport system. (237 aa)
STY4257sn-Glycerol-3-phosphate transport ATP-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa)
gntKPutative gluconokinase; Similar to Escherichia coli thermoresistant gluconokinase GntK SW:GNTK_ECOLI (P46859) (175 aa) fasta scores: E(): 0, 96.0% id in 174 aa and to Escherichia coli thermosensitive gluconokinase IdnK SW:IDNK_ECOLI (P39208) (187 aa) fasta scores: E(): 5.6e-32, 49.7% id in 153 aa. (177 aa)
STY4281MalT regulatory protein; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (901 aa)
feoBFerrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. (772 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
prkBPhosphoribulokinase; Similar to Escherichia coli probable phosphoribulokinase prkB SW:KPPR_ECOLI (P37307) (289 aa) fasta scores: E(): 0, 97.2% id in 289 aa, and to Alcaligenes eutrophus phosphoribulokinase, plasmid cfxP SW:KPPP_ALCEU (P19924) (291 aa) fasta scores: E(): 0, 57.1% id in 287 aa. (289 aa)
yheSSimilar to Escherichia coli hypothetical ABC transporter ATP-binding protein YheS yheS SW:YHES_ECOLI (P45535) (637 aa) fasta scores: E(): 0, 93.4% id in 632 aa, and to Haemophilus influenzae hypothetical ABC transporter ATP-binding protein Hi0658 hi0658 SW:YHES_HAEIN (P44808) (638 aa) fasta scores: E(): 0, 67.9% id in 638 aa, and to Neisseria meningitidis ABC transporter, ATP-binding protein nmb1226 TR:AAF41607 (EMBL:UNNKOWN ACCESSION) (640 aa) fasta scores: E(): 0, 53.1% id in 635 aa; Fasta hit to YBIT_ECOLI (530 aa), 33% identity in 528 aa overlap; Fasta hit to YJJK_ECOLI (554 aa), 3 [...] (635 aa)
fusAElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (704 aa)
STY4426Maltose/maltodextrin transport ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (369 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. (471 aa)
uvrAExcision nuclease subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate; Belongs to the ABC transporter superfamily. UvrA family. (941 aa)
STY4460Putative type-1 secretion protein; Similar to Pasteurella haemolytica leukotoxin secretion ATP-binding protein LktB SW:HLYB_PASHA (P16532) (708 aa) fasta scores: E(): 0, 27.0% id in 567 aa, Salmonella typhimurium LtkB homolog SPI4_R TR:O85327 (EMBL:AF060869) (598 aa) fasta scores: E(): 0, 99.2% id in 598 aa and Escherichia coli hemolysin secretion ATP-binding protein HlyB SW:HLYB_ECOLI (P08716) (707 aa) fasta scores: E(): 3.5e-31, 24.1% id in 713 aa. Contains possible membrane spanning hydrophobic domains. (688 aa)
STY4521Hypothetical protein; Weakly similar to the C-terminus of several polysaccharide biosynthesis proteins e.g. Streptococcus pneumoniae capsular polysaccharide synthesis protein Cps14D TR:P72512 (EMBL:X85787) (227 aa) fasta scores: E(): 1.7e-06, 32.8% id in 189 aa. (344 aa)
STY4522DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (454 aa)
pilQNucleotide-binding protein; Previously sequenced Salmonella typhi PilQ TR:Q9LBE1 (EMBL:AF000001) (571 aa) fasta scores: E(): 0, 100.0% id in 571aa. Also similar to Escherichia coli plasmid IncI1 R64 nucleotide-binding protein PilQ TR:O07375 (EMBL:D88588) (517 aa) fasta scores: E(): 0, 51.3% id in 519 aa. (571 aa)
STY4562Hypothetical protein; Similar to Salmonella typhi plasmid R27 hypothetical protein TraG TR:Q9L5M3 (EMBL:AF250878) (694 aa) fasta scores: E(): 9e-18, 25.9% id in 630 aa. Contains a hydrophobic region towards the N-terminus. (696 aa)
STY4573Hypothetical protein; Weakly similar in parts to Helicobacter pylori J99 DNA transfer protein virb4_2 TR:Q9ZKL8 (EMBL:AE001521) (475 aa) fasta scores: E(): 0.28, 18.6% id in 354 aa. (807 aa)
STY4627Probable terminase subunit; Similar to Bacteriophage P2 terminase, ATPase subunit P SW:VPP_BPP2 (P25479) (590 aa) fasta scores: E(): 0, 63.1% id in 590 aa and to Bacteriophage 186 terminase subunit TR:Q9T0R3 (EMBL:U32222) (589 aa) fasta scores: E(): 0, 63.0% id in 579 aa. (588 aa)
vexCVi polysaccharide export ATP-binding protein; May form an ATP-driven Vi polysaccharide export apparatus, in association with the VexA, VexB and VexD proteins; Belongs to the ABC transporter superfamily. (231 aa)
STY4664Putative DNA helicase; Similar to Escherichia coli helicase IV HelD SW:HELD_ECOLI (P15038) (684 aa) fasta scores: E(): 0.067, 27.5% id in 320 aa and to Salmonella typhi putative DNA helicase TrhI TR:AAF69842 (EMBL:UNNKOWN ACCESSION) (594 aa) fasta scores: E(): 0.24, 19.4% id in 454 aa. (503 aa)
STY4671Putative membrane protein; No database matches. Contains possible membrane spanning hydrophobic domains. (557 aa)
yjeQPutative membrane protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (358 aa)
yjeESimilar to Escherichia coli hypothetical 16.9 kDa protein in psd-amib intergenic region yjeE SW:YJEE_ECOLI (P31805) (153 aa) fasta scores: E(): 0, 94.1% id in 152 aa, and to Haemophilus influenzae hypothetical protein hi0065. protein hi0065 SW:YJEE_HAEIN (P44492) (158 aa) fasta scores: E(): 4.3e-32, 51.7% id in 151 aa. (153 aa)
miaAtRNA delta-2-isopentenylpyrophosphate (IPP) transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa)
hflXHflX protein, putative GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (426 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa)
STY4832Similar to Bacteriophage P4 putative P4-specific DNA primase alpha SW:PRIM_BPP4 (P10277) (777 aa) fasta scores: E(): 0, 86.2% id in 774 aa, and to Haemophilus influenzae phage phi-R73 primase-like protein TR:AAF27348 (EMBL:Q9L8P2) (589 aa) fasta scores: E(): 0, 37.5% id in 432 aa. (777 aa)
STY4849Helicase related protein; Possible helicase. Similar to Deinococcus radiodurans RNA helicase, putative DRB0135 TR:Q9RZJ2 (EMBL:AE001826) (1706 aa) fasta scores: E(): 5.6e-16, 24.4% id in 810 aa. C-terminal region of the protein is similar to the C-terminal region of Escherichia coli McrD protein SW:MCRD_ECOLI (P27301) (409 aa) fasta scores: E(): 0, 62.3% id in 273 aa. N-terminal region of the protein is similar to the N-terminal region of mcrD and to the C-terminus of Escherichia coli hypothetical 58.2 kDa protein in iadA-mcrD intergenic region YjiV SW:YJIV_ECOLI (P39393; P39392) (513 [...] (1249 aa)
STY4850DEAD-box helicase-related protein; Possible helicase. C-terminal of the protein is similar to the N-terminal region of the Escherichia coli hypothetical 58.2 kDa protein in iadA-mcrD intergenic region YjiV SW:YJIV_ECOLI (P39393; P39392) (513 aa) fasta scores: E(): 0, 80.9% id in 362 aa. (845 aa)
STY0214ATP-dependent helicase HrpB; Orthologue of E. coli hrpB (HRPB_ECOLI); Fasta hit to HRPB_ECOLI (809 aa), 85% identity in 809 aa overlap. (813 aa)
hsdRSubunit R of type I restriction-modification system; Similar to Escherichia coli type i restriction enzyme ecok i r protein hsdr or hsR SW:T1R_ECOLI (P08956) (1188 aa) fasta scores: E(): 0, 91.9% id in 1169 aa. (1169 aa)
STY4888Similar to Escherichia coli hypothetical 32.0 kDa protein in mrr-tsr intergenic region yjiA SW:YJIA_ECOLI (P24203) (284 aa) fasta scores: E(): 0, 90.5% id in 284 aa. (318 aa)
dnaCSimilar to Escherichia coli DNA replication protein DnaC dnaC or dnaD SW:DNAC_ECOLI (P07905) (245 aa) fasta scores: E(): 0, 93.5% id in 245 aa. (245 aa)
STY4910Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa)
radAPutative DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa)
nadRConserved hypothetical transcriptional regulator; Bifunctional protein. DNA binding, contains helix-turn-helix. Transporter, interacts with NcuC transporting NMN into the cell. Similar to Salmonella typhimurium transcriptional regulator NadR SW:NADR_SALTY (P24518) (409 aa) fasta scores: E(): 0, 98.8% id in 410 aa, and to Escherichia coli transcriptional regulator NadR SW:NADR_ECOLI (P27278; P76819) (410 aa) fasta scores: E(): 0, 94.6% id in 409 aa. (410 aa)
STY4928Similar to Escherichia coli ABC transporter ATP-binding protein YjjK SW:YJJK_ECOLI (P37797) (554 aa) fasta scores: E(): 0, 97.1% id in 554 aa, and to Haemophilus influenzae ABC transporter ATP-binding protein HI1252 SW:YJJK_HAEIN (P45127) (556 aa) fasta scores: E(): 0, 86.8% id in 554 aa. (555 aa)
STY0111Probable ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa)
STY0123Hypothetical ABC transporter; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (235 aa)
STY0156Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa)
STY0162Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa)
STY0165Similar to Escherichia coli protein transport protein HofB of HopB SW:HOFB_ECOLI (P36645; P75649; Q47022) fasta scores: E(): 0, 69.7% id in 459 aa, and to Pseudomonas aeruginosa fimbrial assembly protein PilB SW:PILB_PSEAE (P22608) fasta scores: E(): 0, 38.4% id in 485 aa, and to Vibrio cholerae general secretion pathway protein e EPSE SW:GSPE_VIBCH (P37093) fasta scores: E(): 0, 46.0% id in 378 aa; Fasta hit to GSPE_ECOLI (493 aa), 44% identity in 400 aa overlap; Orthologue of E. coli hofB (HOFB_ECOLI); Fasta hit to HOFB_ECOLI (461 aa), 70% identity in 459 aa overlap. (461 aa)
STY0194Hypothetical ABC transporter ATP-binding protein; Orthologue of E. coli yadG (YADG_ECOLI); Fasta hit to YADG_ECOLI (308 aa), 95% identity in 308 aa overlap. (308 aa)
STY0219Ferrichrome transport ATP-binding protein FhuC; Fasta hit to FEPC_ECOLI (271 aa), 44% identity in 237 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 44% identity in 239 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 30% identity in 225 aa overlap; Fasta hit to PHNK_ECOLI (252 aa), 30% identity in 217 aa overlap; Fasta hit to HISP_ECOLI (257 aa), 32% identity in 224 aa overlap; Fasta hit to BTUD_ECOLI (249 aa), 35% identity in 232 aa overlap; Fasta hit to PHNL_ECOLI (226 aa), 33% identity in 216 aa overlap; Fasta hit to PHNC_ECOLI (262 aa), 32% identity in 232 aa overlap; Fasta hit to NIK [...] (265 aa)
STY0274Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
STY0294ClpB-like protein; Similar to Escherichia coli ClpB heat shock protease SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 37.9% id in 892 aa; Paralogue of E. coli clpB (CLPB_ECOLI); Fasta hit to CLPB_ECOLI (857 aa), 38% identity in 892 aa overlap; Belongs to the ClpA/ClpB family. (887 aa)
prpRSimilar to Salmonella typhimurium propionate catabolism operon regulatory protein. propionate catabolism operon regulatory protein SW:PRPR_SALTY () (541 aa) fasta scores: E(): 0, 98.9% id in 541 aa, and to Escherichia coli propionate catabolism operon regulatory protein prpR SW:PRPR_ECOLI (P77743) (528 aa) fasta scores: E(): 0, 79.8% id in 530 aa; Fasta hit to YGAA_ECOLI (529 aa), 33% identity in 509 aa overlap; Orthologue of E. coli PRPR_ECOLI; Fasta hit to PRPR_ECOLI (528 aa), 80% identity in 530 aa overlap. (541 aa)
STY0553Hypothetical ABC transporter ATP-binding protein; Fasta hit to ARTP_ECOLI (242 aa), 37% identity in 214 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 44% identity in 216 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 39% identity in 214 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 34% identity in 206 aa overlap; Fasta hit to FECE_ECOLI (255 aa), 31% identity in 212 aa overlap; Fasta hit to GLTL_ECOLI (241 aa), 36% identity in 217 aa overlap; Fasta hit to CCMA_ECOLI (205 aa), 32% identity in 199 aa overlap; Fasta hit to HISP_ECOLI (257 aa), 35% identity in 237 aa overlap; Fasta hit to F [...] (228 aa)
STY0421Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (181 aa)
STY0429Exonuclease SbcC; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily. (1034 aa)
phnTProbable ATP-binding component of 2-aminoethylphosphonate transporter; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system (By similarity). (369 aa)
STY0491ATP-dependent clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (423 aa)
STY0492Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (784 aa)
mdlAPutative ABC transporter ATP-binding membrane protein; Similar to Escherichia coli multidrug resistance-like ATP-binding protein mdla mdla or mdL SW:MDLA_ECOLI (P77265; P30751) (590 aa) fasta scores: E(): 0, 89.0% id in 590 aa, and to many ABC transporters e.g. Bacillus subtilis hypothetical 65.1 kDa protein yheI TR:O07550 (EMBL:Y14080) (585 aa) fasta scores: E(): 0, 39.8% id in 575 aa, and to Thermotoga maritima ABC transporter, ATP-binding protein tm1256 TR:Q9X0Y3 (EMBL:AE001781) (577 aa) fasta scores: E(): 0, 33.3% id in 567 aa; Orthologue of E. coli mdlA (MDLA_ECOLI); Fasta hit to [...] (590 aa)
STY0504Putative ABC transporter ATP-binding membrane protein; Similar to Escherichia coli multidrug resistance-like ATP-binding protein mdlb mdlb or mdL SW:MDLB_ECOLI (P75706; P30751; P77117) (593 aa) fasta scores: E(): 0, 87.7% id in 593 aa, and to many ABC transporters e.g. Mycobacterium tuberculosis hypothetical ABC transporter ATP-binding protein rv1272c rv1272c or mtcy50.10 SW:YC72_MYCTU (Q11047) (631 aa) fasta scores: E(): 0, 35.0% id in 523 aa, and to Rattus norvegicus tap-like ABC transporter tapL TR:Q9QYJ4 (EMBL:AB027520) (762 aa) fasta scores: E(): 0, 33.2% id in 585 aa; Orthologue [...] (593 aa)
STY0528DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (642 aa)
STY0532Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
STY0548Putative ABC transporter ATP-binding protein; Fasta hit to ARTP_ECOLI (242 aa), 31% identity in 216 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 33% identity in 192 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 33% identity in 204 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 31% identity in 210 aa overlap; Fasta hit to FTSE_ECOLI (222 aa), 35% identity in 204 aa overlap; Fasta hit to YECC_ECOLI (250 aa), 32% identity in 216 aa overlap; Fasta hit to P76909 (246 aa), 33% identity in 215 aa overlap; Fasta hit to YRBF_ECOLI (269 aa), 32% identity in 227 aa overlap; Fasta hit to YABJ_ECOL [...] (225 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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