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flhB flhB mukB mukB STY0148 STY0148 fliD fliD STY2130 STY2130 STY2129 STY2129 STY1222 STY1222 wza wza STY2184 STY2184 STY2182 STY2182 STY2180 STY2180 STY2179 STY2179 STY2177 STY2177
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
flhBFlagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (383 aa)
mukBCell division protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1488 aa)
STY0148Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa)
fliDFlagellar hook associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (467 aa)
STY2130Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap. (671 aa)
STY2129Similar to many e.g. Salmonella typhimurium chemotaxis protein CheW cheW SW:CHEW_SALTY (P06110) (167 aa) fasta scores: E(): 0, 99.4% id in 167 aa; Orthologue of E. coli cheW (CHEW_ECOLI); Fasta hit to CHEW_ECOLI (167 aa), 92% identity in 167 aa overlap. (167 aa)
STY1222Flagellar hook-associated protein 1; Orthologue of E. coli flgK (FLGK_ECOLI); Fasta hit to FLGK_ECOLI (546 aa), 80% identity in 554 aa overlap. (553 aa)
wzaPutative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. (379 aa)
STY2184Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (334 aa)
STY2182Similar to Salmonella typhimurium flagellar hook-length control protein fliK or FlaE or flaR SW:FLIK_SALTY (P26416) (405 aa) fasta scores: E(): 0, 97.3% id in 409 aa; Orthologue of E. coli fliK (FLIK_ECOLI); Fasta hit to FLIK_ECOLI (375 aa), 49% identity in 414 aa overlap. (409 aa)
STY2180Similar to Salmonella typhimurium flagellum-specific ATP synthase fliI or flaC SW:FLII_SALTY (P26465) (456 aa) fasta scores: E(): 0, 99.6% id in 456 aa; Fasta hit to ATPB_ECOLI (459 aa), 30% identity in 416 aa overlap; Orthologue of E. coli fliI (FLII_ECOLI); Fasta hit to FLII_ECOLI (457 aa), 93% identity in 456 aa overlap. (456 aa)
STY2179Similar to Salmonella typhimurium flagellar assembly protein FliH fliH SW:FLIH_SALTY (P15934) (235 aa) fasta scores: E(): 0, 99.6% id in 235 aa; Orthologue of E. coli fliH (FLIH_ECOLI); Fasta hit to FLIH_ECOLI (228 aa), 82% identity in 235 aa overlap. (235 aa)
STY2177Flagellar basal-body M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (560 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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