node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0520 | STY0521 | gene:17584541 | gene:17584542 | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Potential acrAB operon repressor; Fasta hit to ENVR_ECOLI (220 aa), 38% identity in 203 aa overlap; Orthologue of E. coli acrR (ACRR_ECOLI); Fasta hit to ACRR_ECOLI (215 aa), 87% identity in 214 aa overlap. | 0.943 |
STY0520 | STY1002 | gene:17584541 | gene:17584990 | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | 0.602 |
STY0520 | STY2499 | gene:17584541 | gene:17586401 | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.663 |
STY0520 | STY3351 | gene:17584541 | gene:17587209 | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.675 |
STY0520 | STY3943 | gene:17584541 | gene:17587803 | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.421 |
STY0521 | STY0520 | gene:17584542 | gene:17584541 | Potential acrAB operon repressor; Fasta hit to ENVR_ECOLI (220 aa), 38% identity in 203 aa overlap; Orthologue of E. coli acrR (ACRR_ECOLI); Fasta hit to ACRR_ECOLI (215 aa), 87% identity in 214 aa overlap. | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.943 |
STY0521 | STY2499 | gene:17584542 | gene:17586401 | Potential acrAB operon repressor; Fasta hit to ENVR_ECOLI (220 aa), 38% identity in 203 aa overlap; Orthologue of E. coli acrR (ACRR_ECOLI); Fasta hit to ACRR_ECOLI (215 aa), 87% identity in 214 aa overlap. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.743 |
STY0521 | STY3351 | gene:17584542 | gene:17587209 | Potential acrAB operon repressor; Fasta hit to ENVR_ECOLI (220 aa), 38% identity in 203 aa overlap; Orthologue of E. coli acrR (ACRR_ECOLI); Fasta hit to ACRR_ECOLI (215 aa), 87% identity in 214 aa overlap. | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.604 |
STY1002 | STY0520 | gene:17584990 | gene:17584541 | Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.602 |
STY1002 | STY1091 | gene:17584990 | gene:17585074 | Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | Outer membrane protein A; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | 0.985 |
STY1002 | STY2499 | gene:17584990 | gene:17586401 | Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.409 |
STY1002 | ompC | gene:17584990 | gene:17586395 | Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | Outer membrane protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | 0.966 |
STY1091 | STY1002 | gene:17585074 | gene:17584990 | Outer membrane protein A; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | 0.985 |
STY1091 | ompC | gene:17585074 | gene:17586395 | Outer membrane protein A; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | Outer membrane protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | 0.996 |
STY2499 | STY0520 | gene:17586401 | gene:17584541 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.663 |
STY2499 | STY0521 | gene:17586401 | gene:17584542 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Potential acrAB operon repressor; Fasta hit to ENVR_ECOLI (220 aa), 38% identity in 203 aa overlap; Orthologue of E. coli acrR (ACRR_ECOLI); Fasta hit to ACRR_ECOLI (215 aa), 87% identity in 214 aa overlap. | 0.743 |
STY2499 | STY1002 | gene:17586401 | gene:17584990 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. | 0.409 |
STY2499 | STY3351 | gene:17586401 | gene:17587209 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.483 |
STY2499 | STY3943 | gene:17586401 | gene:17587803 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.999 |
STY3351 | STY0520 | gene:17587209 | gene:17584541 | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | Acriflavin resistance protein A precursor; Fasta hit to YHIU_ECOLI (385 aa), 54% identity in 391 aa overlap; Fasta hit to ACRE_ECOLI (385 aa), 67% identity in 388 aa overlap; Orthologue of E. coli acrA (ACRA_ECOLI); Fasta hit to ACRA_ECOLI (397 aa), 91% identity in 397 aa overlap; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.675 |