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STY0076 | Carbamoyl-phosphate synthase small chain; Orthologue of E. coli carA (CARA_ECOLI); Fasta hit to CARA_ECOLI (382 aa), 93% identity in 382 aa overlap; Belongs to the CarA family. (382 aa) | ||||
STY0077 | Carbamoyl-phosphate synthase large chain; Orthologue of E. coli carB (CARB_ECOLI); Fasta hit to CARB_ECOLI (1072 aa), 98% identity in 1072 aa overlap. (1075 aa) | ||||
STY0241 | Uridine 5'-monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) | ||||
STY0424 | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (94 aa) | ||||
STY0980 | Cytidylate kinase; Orthologue of E. coli cmk (KCY_ECOLI); Fasta hit to KCY_ECOLI (227 aa), 98% identity in 227 aa overlap. (227 aa) | ||||
STY1079 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa) | ||||
STY1201 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (348 aa) | ||||
STY1239 | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) | ||||
STY1301 | Thymidine kinase; Orthologue of E. coli tdk (KITH_ECOLI); Fasta hit to KITH_ECOLI (205 aa), 93% identity in 204 aa overlap. (205 aa) | ||||
STY1344 | orotidine-5'-P decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (245 aa) | ||||
STY1550 | Putative oxidoreductase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimidine degradation sin [...] (248 aa) | ||||
STY2334 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (193 aa) | ||||
STY2335 | Uridine kinase; Orthologue of E. coli udk (URK_ECOLI); Fasta hit to URK_ECOLI (213 aa), 96% identity in 213 aa overlap. (213 aa) | ||||
STY2413 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (294 aa) | ||||
STY2416 | Putative oxidoreductase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). (413 aa) | ||||
STY2506 | Ribonucleoside-diphosphate reductase 1 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (761 aa) | ||||
STY2507 | Similar to Salmonella typhimurium ribonucleoside-diphosphate reductase 1 beta chain nrdB SW:RIR2_SALTY (P37427) (375 aa) fasta scores: E(): 0, 99.7% id in 375 aa; Orthologue of E. coli nrdB (RIR2_ECOLI); Fasta hit to RIR2_ECOLI (375 aa), 98% identity in 375 aa overlap. (376 aa) | ||||
STY2562 | Putative oxetanocin A biosynthetic enzyme; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (199 aa) | ||||
STY2739 | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) | ||||
STY2771 | Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa) | ||||
STY2932 | Ribonucleoside-diphosphate reductase 2 alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (714 aa) | ||||
STY2933 | Ribonucleoside-diphosphate reductase 2 beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (319 aa) | ||||
STY3052 | Stationary-phase survival protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. (253 aa) | ||||
STY3082 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) | ||||
STY3083 | Conserved hypothetical protein; Orthologue of E. coli mazG (MAZG_ECOLI); Fasta hit to MAZG_ECOLI (263 aa), 94% identity in 262 aa overlap. (266 aa) | ||||
STY3108 | Conserved hypothetical protein; Orthologue of E. coli ygdH (YGDH_ECOLI); Fasta hit to YGDH_ECOLI (454 aa), 94% identity in 453 aa overlap. (454 aa) | ||||
STY3142 | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) | ||||
STY3514 | Cytosine deaminase; Orthologue of E. coli codA (CODA_ECOLI); Fasta hit to CODA_ECOLI (426 aa), 84% identity in 426 aa overlap. (426 aa) | ||||
udp | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). (253 aa) | ||||
STY3644 | Similar to Klebsiella aerogenes uridine phosphorylase UDP SW:UDP_KLEAE (O08444) (253 aa) fasta scores: E(): 2.1e-23, 39.4% id in 218 aa, and to Escherichia coli uridine phosphorylase UDP SW:UDP_ECOLI (P12758) (252 aa) fasta scores: E(): 4.5e-23, 38.5% id in 218 aa; Fasta hit to DEOD_ECOLI (238 aa), 34% identity in 203 aa overlap; Paralogue of E. coli udp (UDP_ECOLI); Fasta hit to UDP_ECOLI (252 aa), 39% identity in 218 aa overlap. (247 aa) | ||||
STY3765 | Hypothetical protein; Similar to several 5' nucleosidase family proteins e.g. Thermotoga maritima UDP-sugar hydrolase TR:Q9X2J1 (EMBL:AE001824) (508 aa) fasta scores: E(): 1.1e-30, 32.6% id in 509 aa; Belongs to the 5'-nucleotidase family. (518 aa) | ||||
STY4061 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa) | ||||
STY4063 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (151 aa) | ||||
yrfG | Putative hydrolase; Similar to Escherichia coli hypothetical 25.4 kDa protein in mrca-pcka intergenic region yrfG SW:YRFG_ECOLI (P45801) (222 aa) fasta scores: E(): 0, 85.5% id in 221 aa, and to Pseudomonas sp 2-haloalkanoic acid dehalogenase SW:HAD_PSESP (Q53464) (232 aa) fasta scores: E(): 0.0029, 27.8% id in 144 aa. (236 aa) | ||||
cpdB | Similar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor cpdB SW:CN16_ECOLI (P08331) (647 aa) fasta scores: E(): 0, 90.3% id in 647 aa; Belongs to the 5'-nucleotidase family. (647 aa) | ||||
STY4784 | Hypothetical protein; Similar to Escherichia coli putative allantoinase SW:ALLA_ECOLI (P77671) (453 aa) fasta scores: E(): 0.066, 23.4% id in 436 aa and to Agrobacterium radiobacter D-hydantoinase SW:HYDA_AGRRD (Q44184) (457 aa) fasta scores: E(): 0.00037, 27.0% id in 281 aa. (377 aa) | ||||
nrdD | Similar to Escherichia coli anaerobic ribonucleoside-triphosphate reductase nrdD SW:NRDD_ECOLI (P28903) (712 aa) fasta scores: E(): 0, 96.2% id in 712 aa. (712 aa) | ||||
pyrI | Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (153 aa) | ||||
pyrB | Similar to Salmonella typhimurium aspartate carbamoyltransferase catalytic chain PyrB SW:PYRB_SALTY (P08420) (309 aa) fasta scores: E(): 0, 98.4% id in 310 aa, and to Escherichia coli aspartate carbamoyltransferase catalytic chain PyrB SW:PYRB_ECOLI (P00479) (310 aa) fasta scores: E(): 0, 95.2% id in 310 aa; Fasta hit to OTC2_ECOLI (333 aa), 32% identity in 298 aa overlap; Fasta hit to OTC1_ECOLI (333 aa), 32% identity in 295 aa overlap. (311 aa) | ||||
STY4909 | Similar to Escherichia coli hypothetical 25.3 kDa protein in rimI-prfC intergenic region YjjG SW:YJJG_ECOLI (P33999; P76818) (225 aa) fasta scores: E(): 0, 90.7% id in 225 aa, and to Bacillus subtilis YfnB TR:O06480 (EMBL:D86418) (235 aa) fasta scores: E(): 6.9e-17, 28.6% id in 227 aa. (226 aa) | ||||
deoA | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (440 aa) | ||||
deoD | Similar to Escherichia coli purine nucleoside phosphorylase deod or puP SW:DEOD_ECOLI (P09743) (238 aa) fasta scores: E(): 0, 97.1% id in 238 aa. (239 aa) |