STRINGSTRING
oadB oadB ilvI ilvI STY0136 STY0136 STY0775 STY0775 STY0776 STY0776 STY0777 STY0777 STY0778 STY0778 ybiW ybiW STY0973 STY0973 adh adh STY1419 STY1419 STY1536 STY1536 STY2620 STY2620 STY2911 STY2911 STY2912 STY2912 yqeF yqeF tdcE tdcE oadB-2 oadB-2 STY3577 STY3577 STY3655 STY3655 STY3656 STY3656 STY3855 STY3855 STY3986 STY3986 STY3987 STY3987 frdD frdD frdC frdC frdB frdB frdA frdA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
oadBOxaloacetate decarboxylase beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (433 aa)
ilvISimilar to Escherichia coli acetolactate synthase isozyme iii large subunit ILVI SW:ILVI_ECOLI (P00893; P78045) fasta scores: E(): 0, 92.2% id in 574 aa, and to Buchnera aphidicola acetolactate synthase large subunit ILVI SW:ILVI_BUCAP (O85293) fasta scores: E(): 0, 70.5% id in 572 aa. (574 aa)
STY0136Acetolactate synthase isozyme III small subunit; Orthologue of E. coli ilvH (ILVH_ECOLI); Fasta hit to ILVH_ECOLI (163 aa), 96% identity in 163 aa overlap. (164 aa)
STY0775Succinate dehydrogenase cytochrome b-556 subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (129 aa)
STY0776Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
STY0777Succinate dehydrogenase flavoprotein subunit; Fasta hit to NADB_ECOLI (540 aa), 32% identity in 570 aa overlap; Fasta hit to FRDA_ECOLI (601 aa), 43% identity in 597 aa overlap; Orthologue of E. coli sdhA (DHSA_ECOLI); Fasta hit to DHSA_ECOLI (588 aa), 98% identity in 588 aa overlap; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
STY0778Succinate dehydrogenase iron-sulfur protein; Fasta hit to FRDB_ECOLI (243 aa), 37% identity in 235 aa overlap; Orthologue of E. coli sdhB (DHSB_ECOLI); Fasta hit to DHSB_ECOLI (238 aa), 96% identity in 238 aa overlap; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (239 aa)
ybiWSimilar to Escherichia coli putative formate acetyltransferase 3 ybiW SW:PFLF_ECOLI (P75793) (810 aa) fasta scores: E(): 0, 95.7% id in 810 aa, and to Escherichia coli formate acetyltransferase 2 pflD SW:PFLD_ECOLI (P32674) (765 aa) fasta scores: E(): 0, 38.1% id in 806 aa; Fasta hit to PFLD_ECOLI (765 aa), 38% identity in 805 aa overlap; Orthologue of E. coli PFLF_ECOLI; Fasta hit to PFLF_ECOLI (810 aa), 96% identity in 810 aa overlap. (810 aa)
STY0973Formate acetyltransferase 1; Fasta hit to TDCE_ECOLI (746 aa), 79% identity in 736 aa overlap; Orthologue of E. coli pflB (PFLB_ECOLI); Fasta hit to PFLB_ECOLI (759 aa), 96% identity in 759 aa overlap. (760 aa)
adhAlcohol dehydrogenase; Similar to Escherichia coli aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase adhE or ana SW:ADHE_ECOLI (P17547) (890 aa) fasta scores: E(): 0, 97.3% id in 892 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (892 aa)
STY1419Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbK SW:NIFJ_ECOLI (P52647; P77238) (1174 aa) fasta scores: E(): 0, 92.9% id in 1174 aa; Orthologue of E. coli NIFJ_ECOLI; Fasta hit to NIFJ_ECOLI (1174 aa), 93% identity in 1174 aa overlap. (1174 aa)
STY1536Similar to Escherichia coli aldehyde-dehydrogenase like protein YneI yneI SW:YNEI_ECOLI (P76149; P78220) (462 aa) fasta scores: E(): 0, 79.6% id in 353 aa, and to Escherichia coli aldehyde dehydrogenase A aldA SW:ALDA_ECOLI (P25553) (478 aa) fasta scores: E(): 0, 36.8% id in 348 aa. Contains C-terminal truncation. (375 aa)
STY2620Putative fatty acid oxidation complex alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
STY2911Succinate-semialdehyde dehydrogenase; Fasta hit to ALDA_ECOLI (478 aa), 39% identity in 464 aa overlap; Fasta hit to FEAB_ECOLI (499 aa), 36% identity in 480 aa overlap; Fasta hit to YNEI_ECOLI (462 aa), 32% identity in 445 aa overlap; Fasta hit to ALDB_ECOLI (512 aa), 33% identity in 490 aa overlap; Fasta hit to DHAB_ECOLI (489 aa), 37% identity in 481 aa overlap; Fasta hit to DHAL_ECOLI (495 aa), 34% identity in 485 aa overlap; Fasta hit to ASTD_ECOLI (492 aa), 32% identity in 470 aa overlap; Fasta hit to YDCW_ECOLI (474 aa), 37% identity in 477 aa overlap; Orthologue of E. coli gabD [...] (482 aa)
STY29124-aminobutyrate aminotransferase; Fasta hit to GSA_ECOLI (426 aa), 32% identity in 421 aa overlap; Fasta hit to ARGM_ECOLI (406 aa), 34% identity in 404 aa overlap; Fasta hit to ARGD_ECOLI (405 aa), 36% identity in 411 aa overlap; Fasta hit to BIOA_ECOLI (429 aa), 32% identity in 353 aa overlap; Fasta hit to GOAG_ECOLI (421 aa), 53% identity in 421 aa overlap; Orthologue of E. coli gabT (GABT_ECOLI); Fasta hit to GABT_ECOLI (426 aa), 89% identity in 426 aa overlap; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
yqeFSimilar to Escherichia coli probable acetyl-CoA acetyltransferase YqeF SW:YQEF_ECOLI (Q46939) (393 aa) fasta scores: E(): 0, 91.5% id in 388 aa; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
tdcEProbable formate acetyltransferase; Fasta hit to PFLB_ECOLI (759 aa), 79% identity in 752 aa overlap; Orthologue of E. coli yhaS (TDCE_ECOLI); Fasta hit to TDCE_ECOLI (746 aa), 93% identity in 741 aa overlap. (764 aa)
oadB-2Oxaloacetate decarboxylase beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (433 aa)
STY3577Large (alpha) subunit of the fatty acid-oxidizing multienzyme complex; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa)
STY3655Acetohydroxy acid synthase II, small subunit; Orthologue of E. coli ilvM (ILVM_ECOLI); Fasta hit to ILVM_ECOLI (86 aa), 93% identity in 86 aa overlap. (86 aa)
STY3656Acetolactate synthase large subunit; Fasta hit to ILVB_ECOLI (562 aa), 47% identity in 554 aa overlap; Fasta hit to ILVI_ECOLI (574 aa), 43% identity in 564 aa overlap; Orthologue of E. coli ilvG_2 (ILVG_ECOLI); Fasta hit to ILVG_ECOLI (548 aa), 92% identity in 548 aa overlap. (548 aa)
STY3855Putative oxidoreductase; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (298 aa)
STY3986Acetohydroxy acid synthase I, small subunit; Fasta hit to ILVG_ECOLI (548 aa), 46% identity in 550 aa overlap; Fasta hit to GCL_ECOLI (592 aa), 35% identity in 507 aa overlap; Fasta hit to ILVI_ECOLI (574 aa), 40% identity in 566 aa overlap; Orthologue of E. coli ilvB (ILVB_ECOLI); Fasta hit to ILVB_ECOLI (562 aa), 92% identity in 562 aa overlap. (562 aa)
STY3987Acetohydroxy acid synthase I, small subunit; Orthologue of E. coli ilvN (ILVN_ECOLI); Fasta hit to ILVN_ECOLI (96 aa), 90% identity in 96 aa overlap. (96 aa)
frdDFumarate reductase complex subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
frdCFumarate reductase complex subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
frdBSimilar to Escherichia coli fumarate reductase iron-sulfur protein frdB SW:FRDB_ECOLI (P00364) (243 aa) fasta scores: E(): 0, 95.5% id in 243 aa, and to Proteus vulgaris fumarate reductase iron-sulfur protein frdB SW:FRDB_PROVU (P20921) (244 aa) fasta scores: E(): 0, 83.5% id in 242 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdASimilar to Escherichia coli fumarate reductase flavoprotein subunit SW:FRDA_ECOLI (P00363) (601 aa) fasta scores: E(): 0, 95.3% id in 594 aa, and to Proteus vulgaris fumarate reductase flavoprotein subunit frdA SW:FRDA_PROVU (P20922) (598 aa) fasta scores: E(): 0, 85.5% id in 598 aa. (596 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.