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STY0008 | Molybdopterin biosynthesis Mog protein; Orthologue of E. coli mog (MOG_ECOLI); Fasta hit to MOG_ECOLI (195 aa), 94% identity in 192 aa overlap. (196 aa) | ||||
STY0102 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (159 aa) | ||||
STY0208 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase; Orthologue of E. coli folK (HPPK_ECOLI); Fasta hit to HPPK_ECOLI (158 aa), 82% identity in 158 aa overlap. (159 aa) | ||||
ybaX | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (231 aa) | ||||
STY0836 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) | ||||
STY0837 | Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (170 aa) | ||||
STY0838 | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa) | ||||
STY0840 | Molybdopterin converting factor, subunit 2; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family. (150 aa) | ||||
STY0885 | Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (413 aa) | ||||
STY1237 | 4-amino-4-deoxychorismate lyase; Orthologue of E. coli pabC (PABC_ECOLI); Fasta hit to PABC_ECOLI (269 aa), 70% identity in 269 aa overlap. (269 aa) | ||||
STY1340 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. (196 aa) | ||||
STY1954 | Para-aminobenzoate synthase component I; Orthologue of E. coli pabB (PABB_ECOLI); Fasta hit to PABB_ECOLI (453 aa), 76% identity in 452 aa overlap. (454 aa) | ||||
STY2108 | DATP pyrophosphohydrolase; Orthologue of E. coli ntpA (NTPA_ECOLI); Fasta hit to NTPA_ECOLI (150 aa), 88% identity in 146 aa overlap. (150 aa) | ||||
STY2427 | GTP cyclohydrolase I; Orthologue of E. coli folE (GCH1_ECOLI); Fasta hit to GCH1_ECOLI (221 aa), 96% identity in 220 aa overlap; Belongs to the GTP cyclohydrolase I family. (222 aa) | ||||
STY2596 | Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. (422 aa) | ||||
STY3077 | Highly similar to Escherichia coli putative 6-pyruvoyl tetrahydrobiopterin synthase YgcM SW:PTPS_ECOLI (Q46903) (121 aa) fasta scores: E(): 0, 94.2% id in 120 aa; Orthologue of E. coli PTPS_ECOLI; Fasta hit to PTPS_ECOLI (121 aa), 94% identity in 120 aa overlap. (120 aa) | ||||
STY3078 | MBL fold metallo-hydrolase; Similar to hypothetical proteins of archeal origin e.g. Pyrococcus abyssi hypothetical 30.2 kDa protein pab0518 TR:Q9V0M3 (EMBL:AJ248285) (272 aa) fasta scores: E(): 3.5e-26, 38.7% id in 261 aa, and to Methanobacterium thermoautotrophicum conserved protein mth1101 TR:O27173 (EMBL:AE000880) (260 aa) fasta scores: E(): 2.3e-16, 31.5% id in 251 aa, and to Methanococcus jannaschii hypothetical protein Mj0448 mj0448 SW:Y448_METJA (Q57890) (256 aa) fasta scores: E(): 7.3e-15, 29.4% id in 248 aa, and to Archaeoglobus fulgidus conserved hypothetical protein af0719 T [...] (265 aa) | ||||
STY3080 | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (223 aa) | ||||
STY3107 | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (282 aa) | ||||
folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) | ||||
STY3473 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (282 aa) | ||||
STY3886 | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (194 aa) | ||||
pabA | Similar to Salmonella typhimurium para-aminobenzoate synthase glutamine amidotransferase component ii pabA SW:PABA_SALTY (P06193) (187 aa) fasta scores: E(): 0, 99.5% id in 187 aa, and to Escherichia coli para-aminobenzoate synthase glutamine amidotransferase component ii pabA SW:PABA_ECOLI (P00903) (187 aa) fasta scores: E(): 0, 85.0% id in 187 aa. (187 aa) |