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citB citB citA citA STY0067 STY0067 citD2 citD2 citE2 citE2 citF2 citF2 citX2 citX2 citG2 citG2 STY0231 STY0231 STY0237 STY0237 STY0271 STY0271 STY0392 STY0392 STY0393 STY0393 STY0432 STY0432 STY0433 STY0433 fimZ fimZ STY0628 STY0628 citT citT citG citG STY0669 STY0669 citF citF citE citE citD citD citC-2 citC-2 dpiB dpiB dpiA dpiA STY0707 STY0707 STY0708 STY0708 STY0709 STY0709 STY0710 STY0710 STY0743 STY0743 STY0744 STY0744 STY0745 STY0745 STY0746 STY0746 STY0747 STY0747 STY0786 STY0786 STY0787 STY0787 STY0788 STY0788 STY0819 STY0819 STY1002 STY1002 STY1211 STY1211 STY1270 STY1270 STY1271 STY1271 STY1285 STY1285 STY1286 STY1286 STY1288 STY1288 STY1289 STY1289 STY1290 STY1290 STY1291 STY1291 pcgL pcgL STY1485 STY1485 STY1486 STY1486 STY1487 STY1487 STY1488 STY1488 STY1494 STY1494 STY1523 STY1523 hyaC2 hyaC2 STY1647 STY1647 STY1651 STY1651 ssrA ssrA ssrB ssrB ttrR ttrR ttrB ttrB ttrC ttrC ttrA ttrA pagC pagC pagD pagD STY1914 STY1914 STY1915 STY1915 appC appC STY1921 STY1921 STY2000 STY2000 STY2125 STY2125 STY2126 STY2126 STY2127 STY2127 STY2128 STY2128 STY2129 STY2129 STY2130 STY2130 STY2132 STY2132 STY2133 STY2133 STY2134 STY2134 sirA sirA STY2158 STY2158 fliA fliA fliC fliC STY2190 STY2190 wzc wzc wzb wzb wza wza STY2339 STY2339 STY2340 STY2340 STY2341 STY2341 STY2342 STY2342 STY2343 STY2343 STY2344 STY2344 STY2472 STY2472 ompC ompC STY2494 STY2494 STY2495 STY2495 rcsC rcsC STY2527 STY2527 STY2545 STY2545 STY2632 STY2632 pgtA pgtA pgtB pgtB pgtC pgtC pgtP pgtP STY2718 STY2718 STY2719 STY2719 STY2808 STY2808 STY2809 STY2809 STY2811 STY2811 iroN iroN tctE tctE tctD tctD STY2906 STY2906 STY2907 STY2907 STY2908 STY2908 csrA csrA STY3096 STY3096 yqeF yqeF STY3318 STY3318 hyb0 hyb0 STY3354 STY3354 STY3355 STY3355 tolC tolC cheM cheM STY3395 STY3395 STY3499 STY3499 STY3507 STY3507 STY3634 STY3634 wecB wecB STY3711 STY3711 STY3712 STY3712 STY3713 STY3713 STY3812 STY3812 STY3813 STY3813 STY3874 STY3874 STY3875 STY3875 STY3876 STY3876 STY3926 STY3926 STY3940 STY3940 STY3951 STY3951 STY3956 STY3956 STY3957 STY3957 STY3992 STY3992 STY3993 STY3993 STY3994 STY3994 STY3995 STY3995 STY4189 STY4189 STY4234 STY4234 ompR ompR envZ envZ crp crp pmrB pmrB pmrA pmrA dcuB dcuB dcuR dcuR dcuS dcuS phoN phoN frdD frdD frdC frdC frdB frdB frdA frdA STY4935 STY4935 creC creC arcA arcA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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citBSimilar to Klebsiella pneumoniae transcriptional regulatory protein citb CITB SW:CITB_KLEPN (P52688) fasta scores: E(): 0, 84.6% id in 227 aa, and to Escherichia coli, and Shigella flexneri transcriptional regulatory protein dpia DPIA OR CITB OR MPDA OR CRIR SW:DPIA_ECOLI (Q54149) fasta scores: E(): 0, 47.3% id in 222 aa; Fasta hit to DCUR_ECOLI (239 aa), 30% identity in 225 aa overlap; Paralogue of E. coli criR (DPIA_ECOLI); Fasta hit to DPIA_ECOLI (226 aa), 47% identity in 222 aa overlap. (228 aa)
citASensor kinase cita; Similar to Klebsiella pneumoniae sensor kinase cita CITA SW:CITA_KLEPN (P52687) fasta scores: E(): 0, 83.7% id in 539 aa, and to Escherichia coli sensor kinase dpib DPIB OR CITA OR MPDB SW:DPIB_ECOLI (P77510; O54338) fasta scores: E(): 0, 42.1% id in 532 aa; Paralogue of E. coli DPIB_ECOLI; Fasta hit to DPIB_ECOLI (552 aa), 42% identity in 532 aa overlap. (539 aa)
STY0067[citrate (PRO-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (347 aa)
citD2Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase. (97 aa)
citE2Similar to Klebsiella pneumoniae citrate lyase beta chain CITE SW:CILB_KLEPN (P17725) fasta scores: E(): 0, 89.6% id in 289 aa, and to Escherichia coli citrate lyase beta chain CITE SW:CILB_ECOLI (P77770; O54335) fasta scores: E(): 0, 63.4% id in 290 aa; Paralogue of E. coli CILB_ECOLI; Fasta hit to CILB_ECOLI (302 aa), 63% identity in 290 aa overlap; Belongs to the HpcH/HpaI aldolase family. (289 aa)
citF2Similar to Klebsiella pneumoniae citrate lyase alpha chain CITF SW:CILA_KLEPN (P45413) fasta scores: E(): 0, 91.3% id in 505 aa, and to Escherichia coli citrate lyase alpha chain CITF SW:CILA_ECOLI (P75726; P77102) fasta scores: E(): 0, 72.1% id in 480 aa; Paralogue of E. coli CILA_ECOLI; Fasta hit to CILA_ECOLI (510 aa), 72% identity in 480 aa overlap. (506 aa)
citX2Citx protein; Similar to Escherichia coli citx protein CITX SW:CITX_ECOLI (P77563) fasta scores: E(): 1.5e-26, 43.9% id in 164 aa, and to Leuconostoc mesenteroides citg protein CITG SW:CITG_LEUMC (O53080) fasta scores: E(): 1.1e-11, 28.5% id in 179 aa; Paralogue of E. coli CITX_ECOLI; Fasta hit to CITX_ECOLI (183 aa), 44% identity in 164 aa overlap. (183 aa)
citG2Citg protein; Similar to Klebsiella pneumoniae citg protein CITG SW:CITG_KLEPN (P45414) fasta scores: E(): 0, 70.4% id in 301 aa, and to Escherichia coli citg protein CITG SW:CITG_ECOLI (P77231) fasta scores: E(): 0, 47.4% id in 293 aa; Paralogue of E. coli CITG_ECOLI; Fasta hit to CITG_ECOLI (292 aa), 47% identity in 293 aa overlap. (302 aa)
STY0231Protease DO precursor; Fasta hit to DEGQ_ECOLI (455 aa), 57% identity in 478 aa overlap; Orthologue of E. coli htrA (HTRA_ECOLI); Fasta hit to HTRA_ECOLI (474 aa), 92% identity in 475 aa overlap; Belongs to the peptidase S1C family. (475 aa)
STY0237[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (890 aa)
STY0271RcsF protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. (134 aa)
STY0392Similar to Pseudomonas aeruginosa cyanide insensitive terminal oxidase cioA TR:O07440 (EMBL:Y10528) (488 aa) fasta scores: E(): 0, 73.3% id in 469 aa, and to Bacillus subtilis cytochrome d ubiquinol oxidase subunit i cydA SW:CYDA_BACSU (P94364) (468 aa) fasta scores: E(): 0, 35.3% id in 459 aa; Fasta hit to CYDA_ECOLI (522 aa), 31% identity in 525 aa overlap; Paralogue of E. coli appC (APPC_ECOLI); Fasta hit to APPC_ECOLI (514 aa), 34% identity in 515 aa overlap. (467 aa)
STY0393Probable terminal oxidase subunit II; Similar to Pseudomonas aeruginosa cyanide insensitive terminal oxidase cioB TR:O07441 (EMBL:Y10528) (335 aa) fasta scores: E(): 0, 65.8% id in 336 aa, and to Bacillus subtilis cytochrome d ubiquinol oxidase subunit ii cydB SW:CYDB_BACSU (P94365) (338 aa) fasta scores: E(): 1.3e-23, 27.2% id in 334 aa. (336 aa)
STY0432Phosphate regulon transcriptional regulatory protein PhoB; Fasta hit to TORR_ECOLI (230 aa), 34% identity in 231 aa overlap; Fasta hit to BAER_ECOLI (240 aa), 41% identity in 224 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 34% identity in 220 aa overlap; Fasta hit to YEDW_ECOLI (239 aa), 36% identity in 223 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 39% identity in 232 aa overlap; Fasta hit to YGIX_ECOLI (219 aa), 34% identity in 227 aa overlap; Fasta hit to ARCA_ECOLI (238 aa), 35% identity in 230 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 39% identity in 229 aa overlap; Fasta [...] (229 aa)
STY0433Phosphate regulon sensor protein PhoR; Orthologue of E. coli phoR (PHOR_ECOLI); Fasta hit to PHOR_ECOLI (431 aa), 90% identity in 431 aa overlap. (431 aa)
fimZProbable transcriptional regulator (FimXZ protein); Similar to Salmonella typhimurium fimbriae z protein fimZ SW:FIMZ_SALTY (P26319) (210 aa) fasta scores: E(): 0, 99.0% id in 210 aa, and to Escherichia coli fimbriae z protein fimZ SW:FIMZ_ECOLI (P21502) (210 aa) fasta scores: E(): 0, 71.4% id in 210 aa, and to Bordetella pertussis, Bordetella bronchiseptica, and virulence factors putative positive transcription regulator BvgA bvgA SW:BVGA_BORPE (P16574) (209 aa) fasta scores: E(): 7.7e-28, 39.5% id in 205 aa, and to Escherichia coli putative positive transcription regulator EvgA evgA [...] (210 aa)
STY0628Ferrienterobactin receptor precursor; Fasta hit to CIRA_ECOLI (663 aa), 33% identity in 768 aa overlap; Orthologue of E. coli fepA (FEPA_ECOLI); Fasta hit to FEPA_ECOLI (746 aa), 82% identity in 755 aa overlap. (751 aa)
citTCitrate carrier; Similar to Escherichia coli citrate carrier citT SW:CITT_ECOLI (P77405) (487 aa) fasta scores: E(): 0, 92.2% id in 501 aa, and to Escherichia coli putative tartrate carrier ygjE SW:TTDT_ECOLI (P39414; Q46870) (487 aa) fasta scores: E(): 0, 44.1% id in 494 aa. Contains an expansion of an LV dipeptide repeat (LV)9 relative to E. coli and S. typhimurium between aa 384 and 401; Fasta hit to TTDT_ECOLI (487 aa), 44% identity in 494 aa overlap; Fasta hit to YBHI_ECOLI (477 aa), 33% identity in 507 aa overlap; Orthologue of E. coli CITT_ECOLI; Fasta hit to CITT_ECOLI (487 aa) [...] (501 aa)
citGCitG protein; Orthologue of E. coli CITG_ECOLI; Fasta hit to CITG_ECOLI (292 aa), 76% identity in 292 aa overlap. (298 aa)
STY0669Conserved hypothetical protein; Similar to, but shorter than Escherichia coli CitX protein SW:CITX_ECOLI (P77563) (183 aa) fasta scores: E(): 0, 74.8% id in 135 aa, and to the N-terminus of Haemophilus influenzae citg protein HI0021 SW:CITG_HAEIN (P44458) (416 aa) fasta scores: E(): 1.1e-11, 33.1% id in 130 aa. (139 aa)
citFSimilar to Escherichia coli citrate lyase alpha chain citF SW:CILA_ECOLI (P75726; P77102) (510 aa) fasta scores: E(): 0, 88.0% id in 510 aa, and to Klebsiella pneumoniae citrate lyase alpha chain citF SW:CILA_KLEPN (P45413) (508 aa) fasta scores: E(): 0, 72.6% id in 468 aa; Orthologue of E. coli CILA_ECOLI; Fasta hit to CILA_ECOLI (510 aa), 88% identity in 510 aa overlap. (509 aa)
citESimilar to Escherichia coli citrate lyase beta chain citE SW:CILB_ECOLI (P77770; O54335) (302 aa) fasta scores: E(): 0, 94.7% id in 302 aa, and to Klebsiella pneumoniae citrate lyase beta chain citE SW:CILB_KLEPN (P17725) (289 aa) fasta scores: E(): 0, 63.4% id in 290 aa; Orthologue of E. coli CILB_ECOLI; Fasta hit to CILB_ECOLI (302 aa), 95% identity in 302 aa overlap; Belongs to the HpcH/HpaI aldolase family. (302 aa)
citDCitrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase. (98 aa)
citC-2[citrate (pro-3S)-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (341 aa)
dpiBSensor kinase DpiB; Similar to Escherichia coli sensor kinase dpib dpib or cita or mpdB SW:DPIB_ECOLI (P77510; O54338) (552 aa) fasta scores: E(): 0, 87.0% id in 553 aa, and to Klebsiella pneumoniae sensor kinase CitA citA SW:CITA_KLEPN (P52687) (547 aa) fasta scores: E(): 0, 41.9% id in 537 aa; Orthologue of E. coli DPIB_ECOLI; Fasta hit to DPIB_ECOLI (552 aa), 87% identity in 553 aa overlap. (553 aa)
dpiATranscriptional regulator CriR; Similar to Escherichia coli, and Shigella flexneri transcriptional regulatory protein dpia dpia or citb or mpda or criR SW:DPIA_ECOLI (Q54149) (226 aa) fasta scores: E(): 0, 85.1% id in 208 aa, and to Klebsiella pneumoniae transcriptional regulatory protein CitB citB SW:CITB_KLEPN (P52688) (234 aa) fasta scores: E(): 0, 48.5% id in 204 aa; Orthologue of E. coli criR (DPIA_ECOLI); Fasta hit to DPIA_ECOLI (226 aa), 85% identity in 208 aa overlap. (226 aa)
STY0707Glutamate/aspartate transport ATP-binding protein GltL; Fasta hit to ARTP_ECOLI (242 aa), 43% identity in 242 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 34% identity in 224 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 39% identity in 217 aa overlap; Fasta hit to ZNUC_ECOLI (251 aa), 31% identity in 222 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 37% identity in 218 aa overlap; Fasta hit to LIVF_ECOLI (237 aa), 31% identity in 228 aa overlap; Fasta hit to PHNK_ECOLI (252 aa), 31% identity in 248 aa overlap; Fasta hit to TAUB_ECOLI (255 aa), 31% identity in 243 aa overlap; Fasta hi [...] (241 aa)
STY0708Glutamate/aspartate transport system permease protein GltK; Fasta hit to YECS_ECOLI (222 aa), 37% identity in 214 aa overlap; Fasta hit to GLNP_ECOLI (219 aa), 32% identity in 224 aa overlap; Orthologue of E. coli gltK (GLTK_ECOLI); Fasta hit to GLTK_ECOLI (224 aa), 96% identity in 223 aa overlap. (224 aa)
STY0709Glutamate/aspartate transport system permease protein GltJ; Fasta hit to YECS_ECOLI (222 aa), 32% identity in 216 aa overlap; Orthologue of E. coli gltJ (GLTJ_ECOLI); Fasta hit to GLTJ_ECOLI (246 aa), 95% identity in 246 aa overlap. (246 aa)
STY0710Similar to Escherichia coli amino-acid ABC transporter binding protein YbeJ precursor ybeJ SW:YBEJ_ECOLI (P37902; P41408; P77612) (302 aa) fasta scores: E(): 0, 93.0% id in 302 aa, and to Bacillus stearothermophilus glutamine-binding protein precursor glnH SW:GLNH_BACST (P27676) (262 aa) fasta scores: E(): 3.6e-14, 30.4% id in 263 aa; Orthologue of E. coli ybeJ (YBEJ_ECOLI); Fasta hit to YBEJ_ECOLI (302 aa), 93% identity in 302 aa overlap. (308 aa)
STY0743KDP operon transcriptional regulatory protein; Fasta hit to TORR_ECOLI (230 aa), 31% identity in 218 aa overlap; Fasta hit to BAER_ECOLI (240 aa), 34% identity in 224 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 36% identity in 219 aa overlap; Fasta hit to YEDW_ECOLI (239 aa), 33% identity in 221 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 34% identity in 231 aa overlap; Fasta hit to YGIX_ECOLI (219 aa), 34% identity in 220 aa overlap; Fasta hit to ARCA_ECOLI (238 aa), 31% identity in 228 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 30% identity in 227 aa overlap; Fasta hit to PHOB [...] (225 aa)
STY0744Sensor protein KdpD; Orthologue of E. coli kdpD (KDPD_ECOLI); Fasta hit to KDPD_ECOLI (894 aa), 89% identity in 902 aa overlap. (902 aa)
STY0745Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (195 aa)
STY0746Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (569 aa)
STY0747Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (559 aa)
STY0786Cytochrome d ubiquinol oxidase subunit I; Fasta hit to APPC_ECOLI (514 aa), 62% identity in 506 aa overlap; Orthologue of E. coli cydA (CYDA_ECOLI); Fasta hit to CYDA_ECOLI (522 aa), 96% identity in 522 aa overlap. (522 aa)
STY0787Cytochrome d ubiquinol oxidase subunit II; Fasta hit to APPB_ECOLI (378 aa), 58% identity in 379 aa overlap; Orthologue of E. coli cydB (CYDB_ECOLI); Fasta hit to CYDB_ECOLI (379 aa), 92% identity in 379 aa overlap. (379 aa)
STY0788Putative membrane protein; Similar to Escherichia coli 4.0 kDa protein in cydb-tolq intergenic region SW:YBGT_ECOLI () (37 aa) fasta scores: E(): 7.8e-14, 86.1% id in 36 aa, and to Escherichia coli hypothetical 3.6 kDa protein in appb-appa intergenic region yccB SW:YCCB_ECOLI (P24244) (30 aa) fasta scores: E(): 0.49, 36.0% id in 25 aa. (37 aa)
STY0819Similar to Erwinia chrysanthemi pectinesterase b precursor pemB SW:PMEB_ERWCH (Q47474) (433 aa) fasta scores: E(): 0, 44.8% id in 429 aa, and to Escherichia coli hypothetical 46.1 kDa protein in modc-bioa intergenic region precursor. putative lipoprotein ybhc precursor SW:YBHC_ECOLI () (427 aa) fasta scores: E(): 0, 86.7% id in 427 aa. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site; Orthologue of E. coli ybhC (YBHC_ECOLI); Fasta hit to YBHC_ECOLI (427 aa), 87% identity in 427 aa overlap. (427 aa)
STY1002Outer membrane protein F precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. (363 aa)
STY1211Negative regulator of flagellin synthesis (anti-sigma factor); Orthologue of E. coli flgM (FLGM_ECOLI); Fasta hit to FLGM_ECOLI (97 aa), 80% identity in 96 aa overlap. (97 aa)
STY1270Sensor protein PhoQ, regulator of virulence determinants; Member of the two-component regulatory system PhoP/PhoQ which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides. In low periplasmic Mg(2+), PhoQ functions as a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to PhoP, which results in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), acts as a protein phosphatase that dephosphorylates phosph [...] (487 aa)
STY1271Transcriptional regulatory protein PhoP, regulator of virulence determinants; Member of the two-component regulatory system PhoQ/PhoP which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides. Promotes intramacrophage survival of S.typhi. Is required to enhance bacterial resistance to bile in the human intestinal cells. (224 aa)
STY1285Nitrate/nitrite response regulator protein NarL; Fasta hit to UHPA_ECOLI (196 aa), 34% identity in 203 aa overlap; Fasta hit to NARP_ECOLI (215 aa), 44% identity in 214 aa overlap; Orthologue of E. coli narL (NARL_ECOLI); Fasta hit to NARL_ECOLI (216 aa), 95% identity in 216 aa overlap. (216 aa)
STY1286Nitrate/nitrite sensor protein NarX; Fasta hit to NARQ_ECOLI (566 aa), 30% identity in 598 aa overlap; Orthologue of E. coli narX (NARX_ECOLI); Fasta hit to NARX_ECOLI (598 aa), 86% identity in 598 aa overlap. (598 aa)
STY1288Respiratory nitrate reductase 1 alpha chain; Fasta hit to NARZ_ECOLI (1245 aa), 79% identity in 1247 aa overlap; Orthologue of E. coli narG (NARG_ECOLI); Fasta hit to NARG_ECOLI (1246 aa), 95% identity in 1246 aa overlap; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa)
STY1289Respiratory nitrate reductase 1 beta chain; Fasta hit to NARY_ECOLI (514 aa), 81% identity in 505 aa overlap; Orthologue of E. coli narH (NARH_ECOLI); Fasta hit to NARH_ECOLI (512 aa), 93% identity in 511 aa overlap. (511 aa)
STY1290Respiratory nitrate reductase 1 delta chain; Fasta hit to NARW_ECOLI (231 aa), 55% identity in 233 aa overlap; Orthologue of E. coli narJ (NARJ_ECOLI); Fasta hit to NARJ_ECOLI (236 aa), 88% identity in 236 aa overlap. (236 aa)
STY1291Respiratory nitrate reductase 1 gamma chain; Fasta hit to NARV_ECOLI (226 aa), 72% identity in 224 aa overlap; Orthologue of E. coli narI (NARI_ECOLI); Fasta hit to NARI_ECOLI (225 aa), 92% identity in 225 aa overlap. (225 aa)
pcgLD-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (256 aa)
STY1485Respiratory nitrate reductase 2 gamma chain; Fasta hit to NARI_ECOLI (225 aa), 72% identity in 224 aa overlap; Orthologue of E. coli narV (NARV_ECOLI); Fasta hit to NARV_ECOLI (226 aa), 97% identity in 226 aa overlap. (226 aa)
STY1486Respiratory nitrate reductase 2 delta chain; Fasta hit to NARJ_ECOLI (236 aa), 58% identity in 233 aa overlap; Orthologue of E. coli narW (NARW_ECOLI); Fasta hit to NARW_ECOLI (231 aa), 82% identity in 231 aa overlap. (231 aa)
STY1487Respiratory nitrate reductase 2 beta chain; Fasta hit to NARH_ECOLI (512 aa), 80% identity in 506 aa overlap; Orthologue of E. coli narY (NARY_ECOLI); Fasta hit to NARY_ECOLI (514 aa), 95% identity in 514 aa overlap. (514 aa)
STY1488Respiratory nitrate reductase 2 alpha chain; Fasta hit to NARG_ECOLI (1246 aa), 79% identity in 1247 aa overlap; Orthologue of E. coli narZ (NARZ_ECOLI); Fasta hit to NARZ_ECOLI (1245 aa), 90% identity in 1245 aa overlap; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1242 aa)
STY1494NAD-linked malic enzyme; Orthologue of E. coli sfcA (MAO1_ECOLI); Fasta hit to MAO1_ECOLI (574 aa), 92% identity in 572 aa overlap; Belongs to the malic enzymes family. (577 aa)
STY1523Uptake hydrogenase small subunit; Fasta hit to MBHT_ECOLI (372 aa), 40% identity in 366 aa overlap; Orthologue of E. coli hyaA (MBHS_ECOLI); Fasta hit to MBHS_ECOLI (372 aa), 73% identity in 360 aa overlap. (367 aa)
hyaC2Similar to Escherichia coli probable ni/fe-hydrogenase 1 b-type cytochrome subunit hyaC SW:CYBH_ECOLI (P19929) (235 aa) fasta scores: E(): 0, 54.4% id in 226 aa. (242 aa)
STY1647Similar to Staphylococcus aureus response regulator YycF yycF TR:Q9XCM7 (EMBL:AF136709) (233 aa) fasta scores: E(): 8.8e-28, 37.6% id in 234 aa; Fasta hit to TORR_ECOLI (230 aa), 31% identity in 213 aa overlap; Fasta hit to BAER_ECOLI (240 aa), 34% identity in 229 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 32% identity in 232 aa overlap; Fasta hit to YEDW_ECOLI (239 aa), 34% identity in 233 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 33% identity in 235 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 37% identity in 233 aa overlap; Orthologue of E. coli rstA (RSTA_ECOLI); Fasta hit [...] (243 aa)
STY1651Two component sensor kinase; Orthologue of E. coli rstB (RSTB_ECOLI); Fasta hit to RSTB_ECOLI (433 aa), 82% identity in 433 aa overlap. (434 aa)
ssrAPutative two-component sensor kinase; Similar to Salmonella typhimurium SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 98.1% id in 823 aa, and to Escherichia coli sensor protein TorS SW:TORS_ECOLI (P39453; P75887) (904 aa) fasta scores: E(): 1.3e-26, 27.8% id in 598 aa. (920 aa)
ssrBPutative two-component response regulator; Similar to Salmonella typhimurium SsrB TR:O54305 (EMBL:Z95891) (193 aa) fasta scores: E(): 0, 100.0% id in 193 aa, and to Streptococcus pneumoniae response regulator rr03 TR:Q9S1J7 (EMBL:AJ006393) (210 aa) fasta scores: E(): 1.4e-19, 34.5% id in 206 aa; Fasta hit to UHPA_ECOLI (196 aa), 33% identity in 202 aa overlap; Fasta hit to NARL_ECOLI (216 aa), 32% identity in 198 aa overlap; Paralogue of E. coli uvrY (UVRY_ECOLI); Fasta hit to UVRY_ECOLI (218 aa), 31% identity in 206 aa overlap. (212 aa)
ttrRPutative two-component response regulator; Similar to Salmonella typhimurium TtrR TR:Q9Z4T0 (EMBL:AJ224978) (206 aa) fasta scores: E(): 0, 100.0% id in 206 aa, and to Rhodobacter capsulatus c4-dicarboxylate transport transcriptional regulatory protein DctR SW:DCTR_RHOCA (P37740) (197 aa) fasta scores: E(): 2.1e-22, 39.1% id in 192 aa; Fasta hit to NARL_ECOLI (216 aa), 30% identity in 200 aa overlap; Paralogue of E. coli uhpA (UHPA_ECOLI); Fasta hit to UHPA_ECOLI (196 aa), 34% identity in 196 aa overlap. (206 aa)
ttrBSimilar to Salmonella typhimurium tetrathionate reductase subunit B TtrB TR:Q9Z4S8 (EMBL:AJ224978) (250 aa) fasta scores: E(): 0, 100.0% id in 250 aa and to Salmonella typhimurium thiosulfate reductase electron transport protein PhsB SW:PHSB_SALTY (P37601) (192 aa) fasta scores: E(): 1.1e-25, 46.4% id in 151 aa; Fasta hit to P77375 (239 aa), 33% identity in 228 aa overlap; Paralogue of E. coli nrfC (NRFC_ECOLI); Fasta hit to NRFC_ECOLI (223 aa), 41% identity in 222 aa overlap. (250 aa)
ttrCSimilar to Salmonella typhimurium tetrathionate reductase subunit C TtrC TR:Q9Z4S7 (EMBL:AJ224978) (340 aa) fasta scores: E(): 0, 98.2% id in 340 aa. (340 aa)
ttrASimilar to Salmonella typhimurium tetrathionate reductase subunit A TtrA TR:Q9Z4S6 (EMBL:AJ224978) (1020 aa) fasta scores: E(): 0, 99.7% id in 1020 aa and to Archaeoglobus fulgidus molybdopterin oxidoreductase, molybdopterin binding subunit, putative af0159 TR:O30078 (EMBL:AE001095) (1134 aa) fasta scores: E(): 6.4e-33, 31.1% id in 1000 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1020 aa)
pagCSimilar to Salmonella typhimurium virulence membrane protein pagc precursor. virulence membrane protein pagc precursor SW:PAGC_SALTY (P23988) (188 aa) fasta scores: E(): 0, 95.2% id in 188 aa, and to Salmonella typhimurium RcK protein precursor rcK TR:Q04817 (EMBL:L08613) (185 aa) fasta scores: E(): 0, 51.6% id in 186 aa, and to Yersinia enterocolitica attachment invasion locus protein precursor aiL SW:AIL_YEREN (P16454) (178 aa) fasta scores: E(): 3.7e-14, 36.6% id in 191 aa. (185 aa)
pagDPutative outer membrane virulence protein; Similar to Salmonella typhimurium virulence protein pagd precursor. virulence protein pagd precursor SW:PAGD_SALTY (Q56029) (87 aa) fasta scores: E(): 0, 95.4% id in 87 aa. (87 aa)
STY1914Hydrogenase-1 large chain (nifE hydrogenase); Fasta hit to MBHM_ECOLI (566 aa), 42% identity in 593 aa overlap; Orthlogue of E. coli hyaB (MBHL_ECOLI); Fasta hit to MBHL_ECOLI (597 aa), 91% identity in 597 aa overlap; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa)
STY1915Probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit; Orthologue of E. coli hyaC (CYBH_ECOLI); Fasta hit to CYBH_ECOLI (235 aa), 83% identity in 230 aa overlap. (243 aa)
appCSimilar to Escherichia coli cytochrome bd-II oxidase subunit I SW:APPC_ECOLI (P26459) (514 aa) fasta scores: E(): 0, 95.9% id in 121 aa, and to Klebsiella pneumoniae subunit I of cytochrome bd cydA TR:O05191 (EMBL:Y10012) (521 aa) fasta scores: E(): 0, 81.0% id in 121 aa, and to Escherichia coli cytochrome D ubiquinol oxidase subunit I SW:CYDA_ECOLI (P11026) (522 aa) fasta scores: E(): 0, 81.0% id in 121 aa. (514 aa)
STY1921Probable cytochrome oxidase subunit II; Fasta hit to CYDB_ECOLI (379 aa), 55% identity in 379 aa overlap; Orthologue of E. coli appB (APPB_ECOLI); Fasta hit to APPB_ECOLI (378 aa), 80% identity in 378 aa overlap. (378 aa)
STY2000Putative membrane protein; Similar to Salmonella typhimurium pagO protein SW:PAGO_SALTY (O30646) (304 aa) fasta scores: E(): 0, 98.7% id in 304 aa, and to Yersinia enterocolitica hypothetical 32.3 kDa protein YomA TR:O85268 (EMBL:AF056092) (291 aa) fasta scores: E(): 0, 58.1% id in 284 aa. (304 aa)
STY2125Chemotaxis protein CheY; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity). (129 aa)
STY2126Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa)
STY2127Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (288 aa)
STY2128Similar to Salmonella typhimurium methyl-accepting chemotaxis protein II tar SW:MCP2_SALTY (P02941) (553 aa) fasta scores: E(): 0, 98.7% id in 553 aa. Contains a possible N-terminal signal sequence and hydrophobic, probable membrane-spanning region; Fasta hit to MCP3_ECOLI (546 aa), 47% identity in 523 aa overlap; Fasta hit to MCP4_ECOLI (533 aa), 48% identity in 523 aa overlap; Fasta hit to MCP1_ECOLI (551 aa), 59% identity in 557 aa overlap; Orthologue of E. coli tar (MCP2_ECOLI); Fasta hit to MCP2_ECOLI (553 aa), 79% identity in 554 aa overlap. (553 aa)
STY2129Similar to many e.g. Salmonella typhimurium chemotaxis protein CheW cheW SW:CHEW_SALTY (P06110) (167 aa) fasta scores: E(): 0, 99.4% id in 167 aa; Orthologue of E. coli cheW (CHEW_ECOLI); Fasta hit to CHEW_ECOLI (167 aa), 92% identity in 167 aa overlap. (167 aa)
STY2130Chemotaxis protein CheA; Similar to many e.g. Salmonella typhimurium chemotaxis protein CheA cheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 99.4% id in 671 aa; Orthologue of E. coli cheA (CHEA_ECOLI); Fasta hit to CHEA_ECOLI (654 aa), 85% identity in 672 aa overlap. (671 aa)
STY2132Motility protein A; Identical to Salmonella typhimurium chemotaxis MotA protein motA SW:MOTA_SALTY (P55891) (295 aa) fasta scores: E(): 0, 99.3% id in 295 aa. Contains hydrophobic, probable membrane-spanning regions; Orthologue of E. coli motA (MOTA_ECOLI); Fasta hit to MOTA_ECOLI (295 aa), 93% identity in 295 aa overlap. (295 aa)
STY2133Flagellar transcriptional activator; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (194 aa)
STY2134Flagellar transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (116 aa)
sirAInvasion response-regulator; Similar to many response regulators e.g. Salmonella typhimurium quorum-sensor response-regulator controlling virulence functions SirA sirA TR:P96058 (EMBL:U67869) (218 aa) fasta scores: E(): 0, 99.5% id in 218 aa and Pseudomonas aeruginosa response regulator GacA gacA SW:GACA_PSEAE (Q51373; O06649) (214 aa) fasta scores: E(): 0, 59.8% id in 214 aa; Fasta hit to UHPA_ECOLI (196 aa), 35% identity in 188 aa overlap; Fasta hit to NARP_ECOLI (215 aa), 31% identity in 195 aa overlap; Orthologue of E. coli uvrY (UVRY_ECOLI); Fasta hit to UVRY_ECOLI (218 aa), 97% i [...] (218 aa)
STY2158Cell-division regulatory protein; Similar to Salmonella typhimurium regulator of cell division (suppresses division inhibition A) SdiA TR:O66040 (EMBL:U88651) (240 aa) fasta scores: E(): 0, 98.8% id in 240 aa; Orthologue of E. coli sdiA (SDIA_ECOLI); Fasta hit to SDIA_ECOLI (240 aa), 72% identity in 240 aa overlap. (240 aa)
fliARNA polymerase sigma transcription factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (239 aa)
fliCFlagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (506 aa)
STY2190Colanic acid capsullar biosynthesis activation protein A; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes. (207 aa)
wzcPutative tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). Belongs to the etk/wzc family. (719 aa)
wzbPutative protein-tyrosine phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI). (149 aa)
wzaPutative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. (379 aa)
STY2339Similar to efflux-system proteins e.g. Neisseria gonorrhoeae membrane fusion protein MtrC precursor mtrC SW:MTRC_NEIGO (P43505) (412 aa) fasta scores: E(): 4.8e-26, 32.7% id in 342 aa and Escherichia coli acriflavin resistance protein a precursor acrA or acrE SW:ACRA_ECOLI (P31223) (397 aa) fasta scores: E(): 5.5e-23, 28.9% id in 356 aa. Contains possible N-terminal membrane anchor; Fasta hit to ACRE_ECOLI (385 aa), 31% identity in 331 aa overlap; Orthologue of E. coli YEGM_ECOLI; Fasta hit to YEGM_ECOLI (415 aa), 83% identity in 415 aa overlap; Belongs to the membrane fusion protein ( [...] (413 aa)
STY2340Putative RND-family transporter protein; Fasta hit to YEGO_ECOLI (1025 aa), 50% identity in 1023 aa overlap; Orthologue of E. coli YEGN_ECOLI; Fasta hit to YEGN_ECOLI (1040 aa), 92% identity in 1040 aa overlap; Similar to many. Contains hydrophobic, probable membrane-spanning regions; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. (1040 aa)
STY2341Putative RND-family transporter protein; Fasta hit to YEGN_ECOLI (1040 aa), 50% identity in 1021 aa overlap; Orthologue of E. coli YEGO_ECOLI; Fasta hit to YEGO_ECOLI (1025 aa), 92% identity in 1025 aa overlap; Similar to many. Contains hydrophobic, probable membrane-spanning regions; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. (1026 aa)
STY2342Putative transporter protein; Fasta hit to YIEO_ECOLI (475 aa), 46% identity in 459 aa overlap; Orthologue of E. coli YEGB_ECOLI; Fasta hit to YEGB_ECOLI (471 aa), 86% identity in 469 aa overlap; Similar to many putative major facilitator family transporter proteins. Contains hydrophobic, probable membrane-spanning regions. (470 aa)
STY2343Putative two-component system sensor kinase; Orthologue of E. coli baeS (BAES_ECOLI); Fasta hit to BAES_ECOLI (467 aa), 89% identity in 467 aa overlap. (467 aa)
STY2344Putative two-component system response regulator; Fasta hit to TORR_ECOLI (230 aa), 37% identity in 231 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 35% identity in 223 aa overlap; Fasta hit to RSTA_ECOLI (242 aa), 33% identity in 228 aa overlap; Fasta hit to YGIX_ECOLI (219 aa), 35% identity in 222 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 37% identity in 241 aa overlap; Fasta hit to ARCA_ECOLI (238 aa), 32% identity in 233 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 37% identity in 225 aa overlap; Fasta hit to PHOB_ECOLI (229 aa), 40% identity in 224 aa overlap; Fasta hit to P [...] (240 aa)
STY2472Nitrate/nitrite response regulator protein NarP; Fasta hit to UHPA_ECOLI (196 aa), 37% identity in 195 aa overlap; Fasta hit to FIMZ_ECOLI (210 aa), 30% identity in 200 aa overlap; Fasta hit to CPXR_ECOLI (232 aa), 31% identity in 229 aa overlap; Fasta hit to NARL_ECOLI (216 aa), 43% identity in 214 aa overlap; Fasta hit to UVRY_ECOLI (218 aa), 34% identity in 200 aa overlap; Orthologue of E. coli narP (NARP_ECOLI); Fasta hit to NARP_ECOLI (215 aa), 88% identity in 215 aa overlap. (215 aa)
ompCOuter membrane protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family. (378 aa)
STY2494Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (889 aa)
STY2495Regulator of capsule synthesis B component; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (216 aa)
rcsCSensor protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (948 aa)
STY2527Putative lipopolysaccharide biosynthesis protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (385 aa)
STY2545Putative receptor/regulator protein; Shows weak similarity to Bacillus subtilis chemotaxis CheV protein cheV SW:CHEV_BACSU (P37599) (303 aa) fasta scores: E(): 2.7e-17, 31.4% id in 299 aa and e.g. Vibrio parahaemolyticus chemotaxis CheV homolog cheV TR:Q9X9K3 (EMBL:U12817) (308 aa) fasta scores: E(): 5.7e-26, 32.6% id in 322 aa. (334 aa)
STY2632Similar to Salmonella typhimurium outer membrane protease E precursor pgtE or prtA SW:PGTE_SALTY (P06185) (296 aa) fasta scores: E(): 0, 96.8% id in 277 aa, Yersinia pestis coagulase/fibrinolysin precursor pla SW:COLY_YERPE (P17811) (312 aa) fasta scores: E(): 0, 71.5% id in 312 aa and Escherichia coli protease VII precursor ompT SW:OMPT_ECOLI (P09169) (317 aa) fasta scores: E(): 0, 46.9% id in 320 aa. (312 aa)
pgtASimilar to Salmonella typhimurium phosphoglycerate transport system transcriptional regulatory protein PgtA pgtA SW:PGTA_SALTY (P06184) (415 aa) fasta scores: E(): 0, 98.1% id in 415 aa. (415 aa)
pgtBSimilar to Salmonella typhimurium phosphoglycerate transport system sensor protein PgtB pgtB SW:PGTB_SALTY (P37433) (593 aa) fasta scores: E(): 0, 98.6% id in 513 aa, and to Vibrio cholerae putative phosphoglycerate transport regulatory protein pgtB, vca0705 TR:Q9KLN8 (EMBL:AE004400) (789 aa) fasta scores: E(): 1.4e-26, 25.0% id in 781 aa, and to Rhizobium leguminosarum c4-dicarboxylate transport sensor protein DctB dctB SW:DCTB_RHILE (P10047) (622 aa) fasta scores: E(): 2.7e-21, 35.1% id in 259 aa. (668 aa)
pgtCPhosphoglycerate transport regulatory protein PgtC precursor; Required for pgtP expression, it may act jointly with the PgtA/PgtB signaling proteins. (397 aa)
pgtPSimilar to Salmonella typhimurium phosphoglycerate transporter protein pgtP SW:PGTP_SALTY (P12681) (406 aa) fasta scores: E(): 0, 95.8% id in 406 aa; Fasta hit to UHPT_ECOLI (463 aa), 33% identity in 464 aa overlap; Fasta hit to UHPC_ECOLI (439 aa), 31% identity in 442 aa overlap; Paralogue of E. coli glpT (GLPT_ECOLI); Fasta hit to GLPT_ECOLI (452 aa), 37% identity in 456 aa overlap. (463 aa)
STY2718Nitrate/nitrite sensor protein NarQ; Fasta hit to NARX_ECOLI (598 aa), 31% identity in 594 aa overlap; Orthologue of E. coli narQ (NARQ_ECOLI); Fasta hit to NARQ_ECOLI (566 aa), 88% identity in 563 aa overlap. (566 aa)
STY2719Putative efflux pump; Similar to Pseudomonas aeruginosa multidrug resistance protein MexB mexB SW:MEXB_PSEAE (P52002) (1046 aa) fasta scores: E(): 0, 61.7% id in 1032 aa; Fasta hit to ACRF_ECOLI (1034 aa), 63% identity in 1032 aa overlap; Fasta hit to ACRB_ECOLI (1049 aa), 66% identity in 1036 aa overlap; Fasta hit to YHIV_ECOLI (1037 aa), 60% identity in 1032 aa overlap; Orthologue of E. coli acrD (ACRD_ECOLI); Fasta hit to ACRD_ECOLI (1037 aa), 94% identity in 1037 aa overlap. (1037 aa)
STY2808Nitrogen regulatory protein p-II; P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). (112 aa)
STY2809Similar to many e.g. Escherichia coli transcriptional regulatory protein HydG hydG SW:HYDG_ECOLI (P14375) (441 aa) fasta scores: E(): 0, 44.6% id in 439 aa and Pseudomonas aeruginosa type 4 fimbriae expression regulatory protein PilR pilR SW:PILR_PSEAE (Q00934) (446 aa) fasta scores: E(): 0, 40.2% id in 443 aa; Fasta hit to HYDG_ECOLI (441 aa), 45% identity in 439 aa overlap; Fasta hit to NTRC_ECOLI (469 aa), 42% identity in 404 aa overlap; Fasta hit to YGAA_ECOLI (529 aa), 37% identity in 449 aa overlap; Fasta hit to ATOC_ECOLI (461 aa), 41% identity in 454 aa overlap; Orthologue of E [...] (445 aa)
STY2811Putative sensor kinase protein; C-terminal half shares similarity with e.g. Mycobacterium tuberculosis MtrB mtrB TR:Q50496 (EMBL:U14909) (567 aa) fasta scores: E(): 5.4e-15, 27.6% id in 301 aa and Pseudomonas aeruginosa alginate biosynthesis sensor protein KinB kinB TR:O34206 (EMBL:U97063) (595 aa) fasta scores: E(): 4.3e-14, 30.0% id in 273 aa; Orthologue of E. coli YFHK_ECOLI; Fasta hit to YFHK_ECOLI (496 aa), 87% identity in 460 aa overlap. (461 aa)
iroNSimilar to Salmonella cholerae-suis TonB-dependent outer membrane siderophore receptor protein iroN TR:O54507 (EMBL:U97227) (727 aa) fasta scores: E(): 0, 99.9% id in 727 aa; Fasta hit to CIRA_ECOLI (663 aa), 34% identity in 731 aa overlap; Paralogue of E. coli fepA (FEPA_ECOLI); Fasta hit to FEPA_ECOLI (746 aa), 52% identity in 753 aa overlap. (726 aa)
tctEPutative two-component system sensor kinase; Similar to Salmonella typhi TctE TR:O68289 (EMBL:AF029846) (439 aa) fasta scores: E(): 0, 99.8% id in 421 aa, but with a different N-terminus. Similar to e.g. Streptomyces coelicolor and Streptomyces lividans two-component system CutS proteins cutS or SC2E9.04 SW:CUTS_STRCO (Q03757) (414 aa) fasta scores: E(): 1.3e-17, 29.2% id in 346 aa. (471 aa)
tctDSimilar to Salmonella typhimurium transcriptional regulatory protein TctD SW:TCTD_SALTY (P22104) (224 aa) fasta scores: E(): 0, 99.1% id in 224 aa and Salmonella typhi AJB70 TctD protein TR:O68288 (EMBL:AF029846) (223 aa) fasta scores: E(): 0, 97.3% id in 224 aa; Fasta hit to TORR_ECOLI (230 aa), 31% identity in 226 aa overlap; Fasta hit to BAER_ECOLI (240 aa), 33% identity in 224 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 38% identity in 226 aa overlap; Fasta hit to YEDW_ECOLI (239 aa), 37% identity in 220 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 36% identity in 228 aa overlap [...] (224 aa)
STY2906Putative exported protein; Similar to Bacillus subtilis hypothetical YflP protein yflP TR:O34439 (EMBL:Z99108) (259 aa) fasta scores: E(): 1.7e-11, 26.6% id in 222 aa. Similar to ORFs from Comamonas testosteroni 3-(3-hydroxyphenyl)propionic acid degradation pathway and Alcaligenes eutrophus pathway for biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate); Alcaligenes eutrophus hypothetical protein SW:YGB7_ALCEU (Q44018) (327 aa) fasta scores: E(): 3.6e-10, 27.2% id in 217 aa and Comamonas testosteroni ORF5 protein TR:Q9S154 (EMBL:AB024335) (278 aa) fasta scores: E(): 3.4e-06, 2 [...] (269 aa)
STY2907Putative membrane protein; Unknown function. Contains hydrophobic, probable membrane-spanning regions. (143 aa)
STY2908Putative membrane protein; Similar to Agrobacterium vitis hypothetical protein SW:YZ2R_AGRVI (P70795) (502 aa) fasta scores: E(): 0, 41.6% id in 495 aa. Contains a region highly similar to part of Pseudomonas putida ammonia monooxygenase amoA TR:O69766 (EMBL:Y14338) (509 aa) fasta scores: E(): 8.9e-28, 52.7% id in 165 aa. Contains hydrophobic, probable membrane-spanning regions. (504 aa)
csrACarbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (61 aa)
STY3096Sensor protein; Similar to Escherichia coli sensor protein BarA involved in adaptive response SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 90.0% id in 921 aa; Orthologue of E. coli barA (BARA_ECOLI); Fasta hit to BARA_ECOLI (918 aa), 90% identity in 921 aa overlap. (918 aa)
yqeFSimilar to Escherichia coli probable acetyl-CoA acetyltransferase YqeF SW:YQEF_ECOLI (Q46939) (393 aa) fasta scores: E(): 0, 91.5% id in 388 aa; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
STY3318Hydrogenase-2 large subunit; Fasta hit to MBHL_ECOLI (597 aa), 43% identity in 595 aa overlap; Orthologue of E. coli hybC (MBHM_ECOLI); Fasta hit to MBHM_ECOLI (566 aa), 94% identity in 566 aa overlap; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
hyb0Similar to Escherichia coli hydrogenase-2 small chain precursor Hyb0 SW:MBHT_ECOLI (Q46847) (372 aa) fasta scores: E(): 0, 96.8% id in 372 aa. Contains multiple possible membrane spanning hydrophobic domains. (372 aa)
STY3354Probable two-component system response regulator; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of flhDC (By similarity). (219 aa)
STY3355Probable two-component system sensor histidine kinase; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. May activate QseB by phosphorylation (By similarity). (449 aa)
tolCSimilar to Salmonella enteritidis outer membrane protein TolC precursor tolC SW:TOLC_SALEN (Q54001) (491 aa) fasta scores: E(): 0, 99.0% id in 491 aa, and to Escherichia coli outer membrane protein tolc precursor tolc or mtcb or muka or refI SW:TOLC_ECOLI (P02930) (495 aa) fasta scores: E(): 0, 89.7% id in 495 aa; Orthologue of E. coli tolC (TOLC_ECOLI); Fasta hit to TOLC_ECOLI (495 aa), 90% identity in 495 aa overlap. (491 aa)
cheMSimilar to many including: Escherichia coli methyl-accepting chemotaxis protein II Tar or CheM SW:MCP2_ECOLI (P07017; P76301) (553 aa) fasta scores: E(): 0, 34.7% id in 519 aa; Fasta hit to MCP3_ECOLI (546 aa), 35% identity in 524 aa overlap; Fasta hit to MCP4_ECOLI (533 aa), 33% identity in 525 aa overlap; Fasta hit to MCP1_ECOLI (551 aa), 37% identity in 531 aa overlap; Paralogue of E. coli tar (MCP2_ECOLI); Fasta hit to MCP2_ECOLI (553 aa), 35% identity in 519 aa overlap. (522 aa)
STY3395Aerotaxis receptor protein; Orthologue of E. coli air (AER_ECOLI); Fasta hit to AER_ECOLI (506 aa), 84% identity in 506 aa overlap. (506 aa)
STY3499RNA polymerase sigma-54 factor (sigma-N); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)
STY3507Aerobic respiration control sensor protein; Orthologue of E. coli arcB (ARCB_ECOLI); Fasta hit to ARCB_ECOLI (776 aa), 94% identity in 778 aa overlap. (778 aa)
STY3634UDP-ManNAc dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
wecBUDP-N-acetyl-D-glucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
STY3711Transcriptional regulatory protein; Member of the two-component regulatory system ZraS/ZraR. When activated by ZraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon (By similarity). (441 aa)
STY3712Two-component system sensor protein; Member of the two-component regulatory system ZraS/ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium (By similarity). (465 aa)
STY3713Possible exported protein; Binds zinc. Could be an important component of the zinc- balancing mechanism (By similarity); Belongs to the ZraP family. (151 aa)
STY3812Two-component response regulatory protein; Fasta hit to TORR_ECOLI (230 aa), 32% identity in 233 aa overlap; Fasta hit to BAER_ECOLI (240 aa), 39% identity in 226 aa overlap; Fasta hit to YLCA_ECOLI (227 aa), 36% identity in 232 aa overlap; Fasta hit to RSTA_ECOLI (242 aa), 34% identity in 233 aa overlap; Fasta hit to YEDW_ECOLI (239 aa), 37% identity in 231 aa overlap; Fasta hit to OMPR_ECOLI (239 aa), 40% identity in 230 aa overlap; Fasta hit to YGIX_ECOLI (219 aa), 36% identity in 228 aa overlap; Fasta hit to ARCA_ECOLI (238 aa), 34% identity in 228 aa overlap; Fasta hit to PHOB_ECO [...] (232 aa)
STY3813Similar to Escherichia coli sensor protein governing extracytoplasmic protein-mediated toxicities CpxA SW:CPXA_ECOLI (P08336) (457 aa) fasta scores: E(): 0, 96.9% id in 457 aa. (457 aa)
STY3874Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (469 aa)
STY3875Two-component system sensory histidine kinase; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC. In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC. (349 aa)
STY3876Two-component system, response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa)
STY3926Periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
STY3940Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (466 aa)
STY3951Two-component sensor protein histidine protein kinase; Orthologue of E. coli torS (TORS_ECOLI); Fasta hit to TORS_ECOLI (904 aa), 63% identity in 898 aa overlap. (911 aa)
STY3956trimethylamine-N-oxide reductase precursor; Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. (850 aa)
STY3957TorD protein; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily. (210 aa)
STY3992Two-component system response regulator protein; Fasta hit to NARP_ECOLI (215 aa), 36% identity in 195 aa overlap; Fasta hit to UVRY_ECOLI (218 aa), 36% identity in 202 aa overlap; Fasta hit to NARL_ECOLI (216 aa), 34% identity in 200 aa overlap; Orthologue of E. coli uhpA (UHPA_ECOLI); Fasta hit to UHPA_ECOLI (196 aa), 97% identity in 196 aa overlap. (196 aa)
STY3993Two-component system sensor histidine kinase; Orthologue of E. coli uhpB (UHPB_ECOLI); Fasta hit to UHPB_ECOLI (500 aa), 91% identity in 500 aa overlap. (500 aa)
STY3994Regulatory protein; Similar to Escherichia coli regulatory protein UhpC required for UhpT expression SW:UHPC_ECOLI () (439 aa) fasta scores: E(): 0, 90.2% id in 438 aa. Contains multiple possible membrane spanning hydrophobic domains; Fasta hit to GLPT_ECOLI (452 aa), 36% identity in 448 aa overlap; Fasta hit to UHPT_ECOLI (463 aa), 32% identity in 459 aa overlap; Orthologue of E. coli uhpC (UHPC_ECOLI); Fasta hit to UHPC_ECOLI (439 aa), 90% identity in 438 aa overlap. (442 aa)
STY3995Hexosephosphate transport protein; Fasta hit to GLPT_ECOLI (452 aa), 32% identity in 460 aa overlap; Fasta hit to UHPC_ECOLI (439 aa), 33% identity in 466 aa overlap; Orthologue of E. coli uhpT (UHPT_ECOLI); Fasta hit to UHPT_ECOLI (463 aa), 95% identity in 463 aa overlap. (463 aa)
STY4189C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (428 aa)
STY4234Similar to Salmonella typhimurium methyl-accepting chemotaxis citrate transducer tcp SW:MCPC_SALTY (Q02755) (547 aa) fasta scores: E(): 0, 99.8% id in 547 aa, and to Escherichia coli methyl-accepting chemotaxis protein I CheD SW:MCP1_ECOLI (P02942) (551 aa) fasta scores: E(): 0, 53.4% id in 554 aa. Predicted hydrophobic membrane spanning domains, integral membrane protein. (547 aa)
ompRTwo-component response regulator OmpR; Member of the two-component regulatory system EnvZ/OmpR involved in regulating expression of the outer membrane porins OmpC and OmpF as well as other genes. Unlike E.coli or S.typhimurium both porins are expressed constitutively. Involved in regulation of the biosynthesis of Vi polysaccharide, a capsular antigen thought to be involved in the virulence of S.typhi. Vi antigen is synthesized at low NaCl concentrations (under 0.4 M). Binds to the promoter of both ompC and ompF (By similarity). (239 aa)
envZTwo-component sensor kinase EnvZ; Member of the two-component regulatory system EnvZ/OmpR involved in regulating expression of the outer membrane porins OmpC and OmpF as well as other genes. Unlike E.coli or S.typhimurium both porins are expressed constitutively. Involved in regulation of the biosynthesis of Vi polysaccharide, a capsular antigen thought to be involved in the virulence of S.typhi. Vi antigen is synthesized at low NaCl concentrations (under 0.4 M). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals (By sim [...] (450 aa)
crpCyclic AMP receptor protein,catabolite gene activator; Similar to Salmonella typhimurium, and Klebsiella aerogenes catabolite gene activator crp or cap SW:CRP_SALTY (P06170) (210 aa) fasta scores: E(): 0, 99.5% id in 210 aa, and to Escherichia coli, and Shigella flexneri catabolite gene activator crp or cap or csm SW:CRP_ECOLI (P03020) (210 aa) fasta scores: E(): 0, 99.0% id in 210 aa. (210 aa)
pmrBTwo-component sensor kinase; Similar to Salmonella typhimurium sensor protein PmrB or BasS SW:BASS_SALTY (P36557) (356 aa) fasta scores: E(): 0, 98.9% id in 356 aa, and to Escherichia coli sensor protein BasS SW:BASS_ECOLI (P30844) (363 aa) fasta scores: E(): 0, 85.6% id in 355 aa. (359 aa)
pmrATwo-component response regulator; Similar to Salmonella typhimurium transcriptional regulatory protein PmrA or BasR SW:BASR_SALTY (P36556) (222 aa) fasta scores: E(): 0, 98.6% id in 222 aa, and to Escherichia coli transcriptional regulatory protein BasR SW:BASR_ECOLI (P30843) (222 aa) fasta scores: E(): 0, 90.1% id in 222 aa. (222 aa)
dcuBAnaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (446 aa)
dcuRTwo-component response regulator; Similar to Escherichia coli transcriptional regulatory protein DcuR SW:DCUR_ECOLI (P39271) (239 aa) fasta scores: E(): 0, 88.3% id in 239 aa, and to Bacillus subtilis two-component response regulator CitT TR:O34534 (EMBL:Z99108) (226 aa) fasta scores: E(): 5.2e-19, 31.4% id in 226 aa. Contains helix-turn-helix motif, residues 179 to 200, score 1148 (+3.10 SD). (239 aa)
dcuSTwo-component sensor kinase; Similar to Escherichia coli sensor protein DcuS SW:DCUS_ECOLI (P39272) (543 aa) fasta scores: E(): 0, 81.5% id in 542 aa, and to Bacillus subtilis two-component sensor histidine kinase CitS TR:O34427 (EMBL:Z99108) (542 aa) fasta scores: E(): 0, 30.5% id in 537 aa. (543 aa)
phoNSimilar to Salmonella typhimurium nonspecific acid phosphatase precursor phoN SW:PHON_SALTY (P26976) (250 aa) fasta scores: E(): 0, 94.8% id in 250 aa. (250 aa)
frdDFumarate reductase complex subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
frdCFumarate reductase complex subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
frdBSimilar to Escherichia coli fumarate reductase iron-sulfur protein frdB SW:FRDB_ECOLI (P00364) (243 aa) fasta scores: E(): 0, 95.5% id in 243 aa, and to Proteus vulgaris fumarate reductase iron-sulfur protein frdB SW:FRDB_PROVU (P20921) (244 aa) fasta scores: E(): 0, 83.5% id in 242 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdASimilar to Escherichia coli fumarate reductase flavoprotein subunit SW:FRDA_ECOLI (P00363) (601 aa) fasta scores: E(): 0, 95.3% id in 594 aa, and to Proteus vulgaris fumarate reductase flavoprotein subunit frdA SW:FRDA_PROVU (P20922) (598 aa) fasta scores: E(): 0, 85.5% id in 598 aa. (596 aa)
STY4935Putative two-component response regulator; Similar to Escherichia coli transcriptional regulatory protein CreB SW:CREB_ECOLI (P08368) (229 aa) fasta scores: E(): 0, 83.4% id in 229 aa, and to Aeromonas jandaei response regulator protein BlrA TR:P97015 (EMBL:U67069) (223 aa) fasta scores: E(): 0, 62.8% id in 226 aa. (229 aa)
creCPutative two-component sensor kinase; Similar to Escherichia coli sensor protein CreC SW:CREC_ECOLI (P08401) (474 aa) fasta scores: E(): 0, 80.4% id in 474 aa, and to Myxococcus xanthus developmental histidine kinase sensor SasS TR:O52223 (EMBL:AF029787) (497 aa) fasta scores: E(): 1.4e-18, 27.5% id in 483 aa. (474 aa)
arcAGlobal response regulator; Similar to Escherichia coli aerobic respiration control protein ArcA SW:ARCA_ECOLI (P03026) (238 aa) fasta scores: E(): 0, 99.6% id in 238 aa, and to Haemophilus influenzae aerobic respiration control protein ArcA homolog ArcA or hi0884 SW:ARCA_HAEIN (P44918) (236 aa) fasta scores: E(): 0, 76.8% id in 237 aa. (238 aa)
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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