| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score | 
| PFL_4162 | PFL_4163 | PFL_4162 | PFL_4163 | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | Histidine kinase.  | 0.873 | 
| PFL_4162 | PFL_4164 | PFL_4162 | PFL_4164 | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | Conserved hypothetical protein.  | 0.813 | 
| PFL_4162 | queC | PFL_4162 | PFL_5031 | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | 0.571 | 
| PFL_4162 | queC1 | PFL_4162 | PFL_4754 | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | 0.571 | 
| PFL_4162 | queF | PFL_4162 | PFL_1967 | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).  | 0.854 | 
| PFL_4163 | PFL_4162 | PFL_4163 | PFL_4162 | Histidine kinase.  | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | 0.873 | 
| PFL_4163 | PFL_4164 | PFL_4163 | PFL_4164 | Histidine kinase.  | Conserved hypothetical protein.  | 0.876 | 
| PFL_4164 | PFL_4162 | PFL_4164 | PFL_4162 | Conserved hypothetical protein.  | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | 0.813 | 
| PFL_4164 | PFL_4163 | PFL_4164 | PFL_4163 | Conserved hypothetical protein.  | Histidine kinase.  | 0.876 | 
| queC | PFL_4162 | PFL_5031 | PFL_4162 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | 0.571 | 
| queC | queC1 | PFL_5031 | PFL_4754 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | 0.914 | 
| queC | queE | PFL_5031 | PFL_4755 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.  | 0.982 | 
| queC | queF | PFL_5031 | PFL_1967 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).  | 0.987 | 
| queC1 | PFL_4162 | PFL_4754 | PFL_4162 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Organic radical activating enzyme family protein; Identified by similarity to SP:P39329.  | 0.571 | 
| queC1 | queC | PFL_4754 | PFL_5031 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | 0.914 | 
| queC1 | queE | PFL_4754 | PFL_4755 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.  | 0.997 | 
| queC1 | queF | PFL_4754 | PFL_1967 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).  | 0.985 | 
| queE | queC | PFL_4755 | PFL_5031 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.  | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | 0.982 | 
| queE | queC1 | PFL_4755 | PFL_4754 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.  | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.  | 0.997 | 
| queE | queF | PFL_4755 | PFL_1967 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.  | Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).  | 0.872 |