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| pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (237 aa) | ||||
| pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (212 aa) | ||||
| guaA | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (518 aa) | ||||
| pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) | ||||
| ctsR | Transcription repressor of class III stress genes; Binds to the ftsH promoter region, leading to repression of its expression. (155 aa) | ||||
| clpC | ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. (837 aa) | ||||
| hrcA | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (347 aa) | ||||
| purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (432 aa) | ||||
| purM | Phosphoribosylformylglycinamidine cyclo-ligase. (341 aa) | ||||
| purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (192 aa) | ||||
| purH | Bifunctional protein: phosphoribosylaminoimidazolecarboxamide formyltransferase; Unknown EC_number=2.1.2.3. (510 aa) | ||||
| purD | Phosphoribosylamine-glycine ligase. (413 aa) | ||||
| infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (858 aa) | ||||
| carB | Carbamoyl-phosphate synthase, large subunit. (1020 aa) | ||||
| pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa) | ||||
| htrA | Serine protease HtrA. (420 aa) | ||||
| pyrR1 | Pyrimidine operon regulator; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes (Probable). Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (180 aa) | ||||
| pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (311 aa) | ||||
| pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (305 aa) | ||||