STRINGSTRING
OB2103 OB2103 OB2108 OB2108 OB2208 OB2208 OB2215 OB2215 OB2299 OB2299 menF menF pgi pgi dapF dapF pgm pgm tpi tpi OB2563 OB2563 rbsD rbsD topB topB OB2609 OB2609 OB2699 OB2699 OB2704 OB2704 OB2765 OB2765 OB2795 OB2795 OB3419 OB3419 OB2797 OB2797 OB2798 OB2798 OB2807 OB2807 OB2813 OB2813 OB2864 OB2864 OB2896 OB2896 OB3037 OB3037 OB3119 OB3119 OB3149 OB3149 OB3226 OB3226 OB3391 OB3391 OB3232 OB3232 gyrB gyrB gyrA gyrA OB0083 OB0083 OB0150 OB0150 OB0177 OB0177 OB0232 OB0232 OB0275 OB0275 OB0366 OB0366 OB0367 OB0367 OB0493 OB0493 OB0496 OB0496 OB0523 OB0523 OB0537 OB0537 OB0544 OB0544 OB0548 OB0548 OB0611 OB0611 OB0620 OB0620 groEL groEL OB0739 OB0739 OB0849 OB0849 OB0901 OB0901 dhbC dhbC OB1127 OB1127 prsA prsA OB1222 OB1222 OB1360 OB1360 OB1486 OB1486 OB1511 OB1511 topA topA truB truB grlB grlB grlA grlA aroH aroH OB1823 OB1823 ppiB ppiB drm drm queA queA pheA pheA hemL hemL OB2078 OB2078
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OB2103Hypothetical protein; CDS_ID OB2103. (312 aa)
OB2108Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (274 aa)
OB2208Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (344 aa)
OB2215Unknown conserved protein (partial); CDS_ID OB2215. (382 aa)
OB229916S pseudouridine synthase; CDS_ID OB2299; Belongs to the pseudouridine synthase RsuA family. (237 aa)
menFMenaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (461 aa)
pgiGlucose-6-phosphate isomerase; CDS_ID OB2336. (448 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (286 aa)
pgm2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1); Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. (512 aa)
tpiTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
OB2563Hypothetical conserved protein; CDS_ID OB2563. (322 aa)
rbsDRibose ABC transporter permease; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (131 aa)
topBDNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] (720 aa)
OB2609Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa)
OB2699Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa)
OB2704Hypothetical conserved protein; CDS_ID OB2704. (185 aa)
OB2765Mannose-6-phosphate isomerase; CDS_ID OB2765; Belongs to the mannose-6-phosphate isomerase type 1 family. (319 aa)
OB2795N-acetylmannosamine-6-P epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (222 aa)
OB3419Hypothetical protein; CDS_ID OB3419. (273 aa)
OB2797L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (494 aa)
OB2798L-ribulose-5-phosphate 4-epimerase; CDS_ID OB2798. (231 aa)
OB2807Hypothetical conserved protein; CDS_ID OB2807. (185 aa)
OB28135-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (277 aa)
OB28645-carboxymethyl-2-hydroxymuconate isomerase; CDS_ID OB2864. (128 aa)
OB2896Capsular polysaccharide biosynthesis; CDS_ID OB2896. (608 aa)
OB3037Phosphomannomutase; CDS_ID OB3037. (577 aa)
OB3119Xylose isomerase; CDS_ID OB3119; Belongs to the xylose isomerase family. (439 aa)
OB3149Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (376 aa)
OB3226D-alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (392 aa)
OB3391Amino acid racemase; CDS_ID OB3391; Belongs to the aspartate/glutamate racemases family. (231 aa)
OB3232Hypothetical conserved protein; CDS_ID OB3232. (278 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (641 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (837 aa)
OB0083Protein secretion (post-translocation molecular chaperone); CDS_ID OB0083. (303 aa)
OB0150tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (253 aa)
OB0177Hypothetical conserved protein; CDS_ID OB0177. (678 aa)
OB0232Phosphoglucomutase (glycolysis); Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (446 aa)
OB0275Thioredoxin; CDS_ID OB0275. (109 aa)
OB0366Hypothetical conserved protein; CDS_ID OB0366. (490 aa)
OB0367Uronate isomerase (glucuronate isomerase); CDS_ID OB0367. (472 aa)
OB0493Hypothetical conserved protein; Involved in the anomeric conversion of L-rhamnose. (104 aa)
OB0496L-rhamnose isomerase; CDS_ID OB0496; Belongs to the rhamnose isomerase family. (417 aa)
OB0523Phosphoribosylanthranilate isomerase; CDS_ID OB0523; Belongs to the TrpF family. (204 aa)
OB0537Isopentenyl-diphosphate delta-isomerase (IPP isomerase); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)
OB0544Hypothetical protein; CDS_ID OB0544. (242 aa)
OB0548Phosphoribosyl formimino-5-aminoimidazole isomerase; CDS_ID OB0548. (240 aa)
OB0611N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (250 aa)
OB0620Hypothetical conserved protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] (509 aa)
groELClass I heat shock protein (chaperonin); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (545 aa)
OB0739Phosphoribosylaminoimidazole carboxylase I; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa)
OB0849Hypothetical conserved protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (303 aa)
OB0901Glutamate-1-semialdehyde aminotransferase; CDS_ID OB0901. (432 aa)
dhbCIsochorismate synthase; CDS_ID OB0955. (398 aa)
OB1127Spore coat polysaccharide synthesis (dTDP-4-dehydrorhamnose epimerase); CDS_ID OB1127. (151 aa)
prsAProtein secretion (post-translocation molecular chaperone); Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (299 aa)
OB1222Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (322 aa)
OB1360Peptidyl-prolyl cis-trans isomerase B (ppiase B) (rotamase B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (202 aa)
OB1486Hypothetical conserved protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (303 aa)
OB1511Ribulose-phosphate 3-epimerase; CDS_ID OB1511; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (692 aa)
truBtRNA-pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (303 aa)
grlBDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (651 aa)
grlADNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily. (816 aa)
aroHChorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (125 aa)
OB1823Ribosomal large subunit pseudouridylate synthase; CDS_ID OB1823; Belongs to the pseudouridine synthase RsuA family. (244 aa)
ppiBPeptidyl-prolyl cis-trans isomerase B (ppiase B) (rotamase B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (143 aa)
drmPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (392 aa)
queAS-adenosylmethionine-tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (342 aa)
pheAPrephenate dehydratase; CDS_ID OB2041. (284 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8); CDS_ID OB2065. (428 aa)
OB2078Trigger factor (prolyl isomerase); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (428 aa)
Your Current Organism:
Oceanobacillus iheyensis
NCBI taxonomy Id: 221109
Other names: O. iheyensis HTE831, Oceanobacillus iheyensis HTE831, Oceanobacillus iheyensis str. HTE831, Oceanobacillus iheyensis strain HTE831, marine firmicute HTE831
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