STRINGSTRING
AAO53646.1 AAO53646.1 AAO53742.1 AAO53742.1 gcvT-1 gcvT-1 gcvH-1 gcvH-1 glnA-1 glnA-1 AAO53938.1 AAO53938.1 AAO53939.1 AAO53939.1 AAO53940.1 AAO53940.1 AAO53941.1 AAO53941.1 etfA-1 etfA-1 etfB-1 etfB-1 AAO53945.1 AAO53945.1 AAO53946.1 AAO53946.1 AAO53954.1 AAO53954.1 folA folA fdhA-1 fdhA-1 purU-1 purU-1 soxG-1 soxG-1 soxA-1 soxA-1 soxD-1 soxD-1 soxB-1 soxB-1 glyA-1 glyA-1 AAO54506.1 AAO54506.1 murI murI AAO54710.1 AAO54710.1 gcvT-2 gcvT-2 gcvP gcvP gcvH-2 gcvH-2 amiE amiE AAO54975.1 AAO54975.1 purT purT adhC adhC AAO55079.1 AAO55079.1 AAO55360.1 AAO55360.1 AAO55439.1 AAO55439.1 gltX gltX nasA nasA AAO55816.1 AAO55816.1 AAO55818.1 AAO55818.1 nasT nasT AAO55821.1 AAO55821.1 AAO55822.1 AAO55822.1 AAO55936.1 AAO55936.1 soxG-2 soxG-2 soxA-2 soxA-2 soxD-2 soxD-2 soxB-2 soxB-2 folD-1 folD-1 purU-2 purU-2 glsA glsA fdhA-2 fdhA-2 AAO56464.1 AAO56464.1 AAO56551.1 AAO56551.1 AAO56685.1 AAO56685.1 nirB nirB nirD nirD folD-2 folD-2 AAO57226.1 AAO57226.1 folC folC fmdA fmdA purU-3 purU-3 glyA-2 glyA-2 gltD gltD gltB gltB thyA thyA AAO58734.1 AAO58734.1 AAO58735.1 AAO58735.1 AAO58736.1 AAO58736.1 rubB rubB rubA rubA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AAO53646.1Aldehyde dehydrogenase family protein; Similar to SP:P23883, GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P23883, GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519, identified by sequence similarity, putative; Belongs to the aldehyde dehydrogenase family. (497 aa)
AAO53742.1Nitrilase, putative; Similar to GP:15143035, and SP:Q03217; identified by sequence similarity; putative. (347 aa)
gcvT-1Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (360 aa)
gcvH-1Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
glnA-1Glutamine synthetase, type I; Identified by match to TIGR protein family HMM TIGR01692; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01692. (468 aa)
AAO53938.1Renal dipeptidase family protein. (325 aa)
AAO53939.1Conserved hypothetical protein; Identified by Glimmer2; putative. (176 aa)
AAO53940.1NADH:flavin oxidoreductase/NADH oxidase family protein. (686 aa)
AAO53941.1Iron-sulfur cluster-binding protein. (669 aa)
etfA-1Electron transfer flavoprotein, alpha subunit. (328 aa)
etfB-1Electron transfer flavoprotein, beta subunit. (265 aa)
AAO53945.1Iron-sulfur cluster-binding protein, Rieske family; Identified by match to PFAM protein family HMM PF00848. (410 aa)
AAO53946.1Iron-sulfur cluster-binding protein; Similar to GP:15073802; identified by sequence similarity; putative. (366 aa)
AAO53954.1Threonine aldolase, low-specificity; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa)
folADihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (170 aa)
fdhA-1Glutathione-independent formaldehyde dehydrogenase; See PMID:20190049 for expression data; similar to SP:P46154, GB:X64318, GB:U26173, GB:S79880, PID:1237118, and PID:30956; identified by sequence similarity; putative. (399 aa)
purU-1Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (285 aa)
soxG-1Sarcosine oxidase, gamma subunit; Similar to SP:Q46338, GB:U11053, GB:U17298, GB:L36130, SP:P41145, PID:532060, PID:595933, PID:596070, PID:598185, and PID:722618; identified by sequence similarity; putative. (210 aa)
soxA-1Sarcosine oxidase, alpha subunit; Similar to SP:Q46337; identified by sequence similarity; putative; Belongs to the GcvT family. (1006 aa)
soxD-1Sarcosine oxidase, delta subunit; Similar to SP:Q46336, GB:U11053, GB:U17298, GB:L36130, SP:P41145, PID:532060, PID:595933, PID:596070, PID:598185, and PID:722618; identified by sequence similarity; putative. (98 aa)
soxB-1Sarcosine oxidase, beta subunit; Similar to GP:14023472, and SP:P40875; identified by sequence similarity; putative. (416 aa)
glyA-1Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
AAO54506.1Iron-sulfur cluster-binding protein, Rieske family; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF00355. (110 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (275 aa)
AAO54710.1Oxidoreductase, short chain dehydrogenase/reductase family; See PMID:20190049 for expression data; similar to GB:X68505, GB:X68505, GB:X63381, GB:X63381, SP:Q02078, SP:Q02080, PID:1197538, PID:34536, and PID:432656; identified by sequence similarity; putative. (236 aa)
gcvT-2Glycine cleavage system T protein; See PMID:20190049 for expression data. (409 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (954 aa)
gcvH-2Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
amiEAliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. (338 aa)
AAO54975.1Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF01244. (329 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (393 aa)
adhCAlcohol dehydrogenase, class III; See PMID:20190049 for expression data. (370 aa)
AAO55079.1Esterase, putative; Serine hydrolase involved in the detoxification of formaldehyde. (281 aa)
AAO55360.1Threonine aldolase, low-specificity; See PMID:20190049 for expression data; similar to SP:P75823; identified by sequence similarity; putative. (334 aa)
AAO55439.1Glutamine synthetase; Identified by match to TIGR protein family HMM TIGR00653; Belongs to the glutamine synthetase family. (447 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (493 aa)
nasANitrate reductase; Similar to GP:15159397, and SP:Q06457; identified by sequence similarity; putative; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (908 aa)
AAO55816.1Assimilatory nitrate reductase electron transfer subunit domain protein; Similar to GP:15159393, and SP:P42435; identified by sequence similarity; putative. (409 aa)
AAO55818.1Nitrate transporter. (403 aa)
nasTResponse regulator NasT. (191 aa)
AAO55821.1Conserved hypothetical protein. (403 aa)
AAO55822.1Hypothetical protein; Identified by Glimmer2; putative. (65 aa)
AAO55936.1Serine hydroxymethyltransferase, putative; Similar to GB:Z35428, PID:515905, and SP:P53522; identified by sequence similarity; putative. (364 aa)
soxG-2Sarcosine oxidase, gamma subunit; Similar to SP:Q46338; identified by sequence similarity; putative. (190 aa)
soxA-2Sarcosine oxidase, alpha subunit; Similar to SP:Q46337; identified by sequence similarity; putative; Belongs to the GcvT family. (968 aa)
soxD-2Sarcosine oxidase, delta subunit; Similar to GP:13241963, and SP:Q46336; identified by sequence similarity; putative. (101 aa)
soxB-2Sarcosine oxidase, beta subunit; Similar to SP:P40875; identified by sequence similarity; putative. (413 aa)
folD-1Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (300 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (288 aa)
glsAGlutaminase, putative; Similar to SP:P77470, SP:P37828, and PID:901847; identified by sequence similarity; putative; Belongs to the glutaminase family. (302 aa)
fdhA-2Glutathione-independent formaldehyde dehydrogenase; Similar to SP:P46154; identified by sequence similarity; putative. (379 aa)
AAO56464.1Oxidoreductase, 2-nitropropane dioxygenase family; Similar to GP:17430775; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:17430775, identified by sequence similarity, putative. (359 aa)
AAO56551.1Iron-sulfur cluster-binding protein, rieske family; Similar to GP:15155696; identified by sequence similarity; putative. (416 aa)
AAO56685.1Oxidoreductase, 2-nitropropane dioxygenase family; Identified by match to PFAM protein family HMM PF03060. (323 aa)
nirBNitrite reductase [NAD(P)H], large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (853 aa)
nirDNitrite reductase [NAD(P)H], small subunit. (128 aa)
folD-2Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
AAO57226.1Conserved protein of unknown function; Identified by match to PFAM protein family HMM PF02812; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02812. (1618 aa)
folCFolylpolyglutamate synthase/dihydrofolate synthase; Similar to GP:146009, and SP:P08192; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to GP:146009, and SP:P0819, identified by sequence similarity, putative; Belongs to the folylpolyglutamate synthase family. (434 aa)
fmdAFormamidase; Similar to GP:4774513, and SP:Q50228; identified by sequence similarity; putative. (410 aa)
purU-3Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (283 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
gltDGlutamate synthase, small subunit; See PMID:20190049 for expression data. (472 aa)
gltBGlutamate synthase, large subunit; See PMID:20190049 for expression data. (1481 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (323 aa)
AAO58734.1Aminotransferase, class III; See PMID:20190049 for expression data; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
AAO58735.1Glutamine synthetase; See PMID:20190049 for expression data; Belongs to the glutamine synthetase family. (452 aa)
AAO58736.1Glutamine synthetase; See PMID:20190049 for expression data; Belongs to the glutamine synthetase family. (458 aa)
rubBRubredoxin reductase; See PMID:20190049 for expression data; Belongs to the FAD-dependent oxidoreductase family. (382 aa)
rubARubredoxin; See PMID:20190049 for expression data. (55 aa)
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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