| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| comN | divIVA | BSU27660 | BSU15420 | Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites. | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | 0.875 |
| comN | minJ | BSU27660 | BSU35220 | Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites. | Topological determinant of cell division; The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD. | 0.949 |
| comN | racA | BSU27660 | BSU37030 | Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites. | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | 0.839 |
| divIVA | comN | BSU15420 | BSU27660 | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites. | 0.875 |
| divIVA | minJ | BSU15420 | BSU35220 | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | Topological determinant of cell division; The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD. | 0.996 |
| divIVA | racA | BSU15420 | BSU37030 | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | 0.998 |
| divIVA | refZ | BSU15420 | BSU29630 | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | Regulator of FtsZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | 0.681 |
| minJ | comN | BSU35220 | BSU27660 | Topological determinant of cell division; The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD. | Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites. | 0.949 |
| minJ | divIVA | BSU35220 | BSU15420 | Topological determinant of cell division; The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD. | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | 0.996 |
| minJ | racA | BSU35220 | BSU37030 | Topological determinant of cell division; The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD. | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | 0.919 |
| racA | comN | BSU37030 | BSU27660 | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites. | 0.839 |
| racA | divIVA | BSU37030 | BSU15420 | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | 0.998 |
| racA | minJ | BSU37030 | BSU35220 | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | Topological determinant of cell division; The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD. | 0.919 |
| racA | refZ | BSU37030 | BSU29630 | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | Regulator of FtsZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | 0.510 |
| refZ | divIVA | BSU29630 | BSU15420 | Regulator of FtsZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation. | 0.681 |
| refZ | racA | BSU29630 | BSU37030 | Regulator of FtsZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Chromosome-anchoring protein RacA; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. | 0.510 |