STRINGSTRING
yesM yesM yesN yesN yesO yesO rhgP rhgP rhgQ rhgQ rhgH rhgH yesS yesS rhgT rhgT yesU yesU yesV yesV
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yesMTwo-component sensor histidine kinase [YesN]; Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation. (577 aa)
yesNTwo-component response regulator [YesM]; Member of the two-component regulatory system YesM/YesN. (368 aa)
yesOPectin degradation byproducts-binding lipoprotein; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the bacterial solute-binding protein 1 family. (427 aa)
rhgPRhamnogalacturonan permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. (309 aa)
rhgQRhamnogalacturonan permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. (296 aa)
rhgHRhamnogalacturonan hydrolase; Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D-glucuronic acid at the non-reducing terminus, although the active pockets of YesR and UGL are very similar. Belongs to the glycosyl hydrolase 105 family. (344 aa)
yesSTranscriptional regulator (AraC/XylS family); Probable transcription factor regulating the pathway responsible for rhamnogalacturonan depolymerization. (761 aa)
rhgTRhamnogalacturonan acetylesterase; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity, and shows strong preference for glucose pentaacetate, beta-naphthylacetate, and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan. (232 aa)
yesUConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16781735, 17449691. (220 aa)
yesVPutative integral inner membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (208 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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