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ycbL ycbL ycbM ycbM ycbN ycbN ycbO ycbO yclH yclH yclI yclI yclJ yclJ yclK yclK swrC swrC yfjR yfjR csbB csbB yfhO yfhO ykcB ykcB ykcC ykcC ykoG ykoG ykoH ykoH ykoI ykoI ykoJ ykoJ ykzD ykzD ykoS ykoS ykoT ykoT kinA kinA yknU yknU yknV yknV yknW yknW yknX yknX yknY yknY yknZ yknZ yngA yngA yngC yngC psiE psiE yrkQ yrkQ yrkP yrkP yrkO yrkO yrkN yrkN bceB bceB bceA bceA bceS bceS bceR bceR ytrF ytrF ytrE ytrE ytrD ytrD ytrC ytrC ytrB ytrB ytrA ytrA BSU30466 BSU30466 ytqA ytqA ytqB ytqB yvrG yvrG yvrH yvrH yvrN yvrN yvrO yvrO yvrP yvrP yvcS yvcS yvcR yvcR yvcQ yvcQ yvcP yvcP yxeA yxeA yxdM yxdM yxdL yxdL yxdK yxdK yxdJ yxdJ yycA yycA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ycbLTwo-component response regulator [YcbM]; Member of the two-component regulatory system YcbM/YcbL. (226 aa)
ycbMTwo-component sensor histidine kinase [YcbL]; Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation. (311 aa)
ycbNPutative ABC efflux transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. (307 aa)
ycbOPutative Na+-driven exporter or maturation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (228 aa)
yclHPutative ABC transporter (ATPase component); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily. (226 aa)
yclIPutative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (486 aa)
yclJTwo-component response regulator [YclK]; Could be member of the two-component regulatory system YclK/YclJ. (227 aa)
yclKTwo-component sensor histidine kinase [YclJ]; Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ. (473 aa)
swrCTransporter involved in surfactin self-resistance; Required for self-resistance to surfactin, an antimicrobial lipopeptide surfactant produced by B.subtilis. Also required for swarming motility; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1052 aa)
yfjRPutative beta-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HIBADH-related family. (286 aa)
csbBPutative glycosyl transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase 2 family. GtrB subfamily. (329 aa)
yfhOConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (861 aa)
ykcBPutative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (716 aa)
ykcCPutative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (323 aa)
ykoGTwo-component response regulator [YkoH]; Probable member of the two-component regulatory system YkoH/YkoG. (228 aa)
ykoHTwo-component sensor histidine kinase [YkoG]; Probable member of the two-component regulatory system YkoH/YkoG. Potentially phosphorylates YkoG. (454 aa)
ykoIConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (226 aa)
ykoJPutative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype. (170 aa)
ykzDConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (45 aa)
ykoSPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (564 aa)
ykoTPutative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase 2 family. (337 aa)
kinASporulation-specific ATP-dependent protein histidine kinase; Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP. (606 aa)
yknUPutative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (585 aa)
yknVPutative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (604 aa)
yknWPutative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex. (231 aa)
yknXPutative efflux permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). (377 aa)
yknYPutative ABC transporter (ATP-binding protein); Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). (230 aa)
yknZPutative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). (397 aa)
yngAPutative conserved membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (148 aa)
yngCPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (198 aa)
psiEPhosphate starvation inducible protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; membrane component. (138 aa)
yrkQTwo-component sensor histidine kinase [YrkP]; Member of the two-component regulatory system YrkQ/YrkP. Probably activates YrkP by phosphorylation. (432 aa)
yrkPTwo-component response regulator [YrkQ]; Member of the two-component regulatory system YrkQ/YrkP. (231 aa)
yrkOPutative integral inner membrane protein; Involved in transport. (405 aa)
yrkNPutative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (185 aa)
bceBABC transporter (permease); Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export; Belongs to the ABC-4 integral membrane protein family. (646 aa)
bceABacitracin ABC efflux transporter (ATP-binding protein); Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export. Responsible for energy coupling to the transport system. (253 aa)
bceSSensor protein BceS; Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin. (334 aa)
bceRSensory transduction protein BceR; Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up- regulates the expression of these two genes. (231 aa)
ytrFMetabolite permease; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation. (436 aa)
ytrEABC transporter (ATP-binding protein); Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation. (231 aa)
ytrDABC transporter, permease component; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation. (325 aa)
ytrCABC transporter, permease component; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation. (328 aa)
ytrBABC transporter (ATP-binding protein); Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation. (292 aa)
ytrATranscriptional regulator (GntR family); Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation. (130 aa)
BSU30466Hypothetical protein; Evidence 5: No homology to any previously reported sequences. (52 aa)
ytqAPutative Fe-S oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (322 aa)
ytqBPutative RNA methylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. (194 aa)
yvrGTwo-component sensor histidine kinase YvrG innvolved in cell wall processes [YvrH]; Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA-yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX-rsiX), and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation. (580 aa)
yvrHTwo-component response regulator YvrH involved in cell wall processes [YvrG]; Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA-yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX-rsiX), and negatively regulates the lytABC operon. (237 aa)
yvrNPutative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (409 aa)
yvrOPutative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. (229 aa)
yvrPPutative ABC transporter component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (397 aa)
yvcSPutative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (646 aa)
yvcRPutative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. (259 aa)
yvcQTwo-component sensor histidine kinase [YvcP]; Member of the two-component regulatory system YvcQ/YvcP. Probably activates YvcP by phosphorylation. (356 aa)
yvcPTwo-component response regulator [YvcQ]; Member of the two-component regulatory system YvcQ/YvcP. (237 aa)
yxeAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (115 aa)
yxdMABC transporter (permease); Part of the ABC transporter complex YxdLM which could be involved in peptide resistance; Belongs to the ABC-4 integral membrane protein family. (622 aa)
yxdLABC transporter (ATP-binding protein); Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Responsible for energy coupling to the transport system (Probable). (257 aa)
yxdKTwo-component sensor histidine kinase [YxdJ]; Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37. (325 aa)
yxdJTwo-component response regulator [YxdK]; Probable member of the two-component regulatory system YxdK/YxdJ. Positively regulates the expression of the yxdLMyxeA operon by direct interaction with its promoter region. Could also indirectly regulate the expression of the dlt operon. (229 aa)
yycAPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (685 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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