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dinB dinB yfiS yfiS bst bst yfiU yfiU yhaZ yhaZ yisL yisL yizA yizA yisP yisP yisT yisT yjoA yjoA ykkA ykkA ohrA ohrA ohrR ohrR ylbK ylbK ylbL ylbL bshC bshC fosB fosB yneA yneA yneB yneB ynzC ynzC bshBB bshBB yojF yojF yoyC yoyC yojE yojE ctpA ctpA bshR bshR ypdA ypdA yqiW yqiW yrdA yrdA ytxJ ytxJ yuaE yuaE tagC tagC yxjG yxjG ppaC ppaC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dinBNuclease inhibitor; Evidence 2b: Function of strongly homologous gene; regulator. (172 aa)
yfiSPutative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (417 aa)
bstBacillithiol S-transferase; Possible metal-dependent hydrolase; Belongs to the metal hydrolase YfiT family. (178 aa)
yfiUPutative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (518 aa)
yhaZConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290. (357 aa)
yisLPutative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (118 aa)
yizAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family. (159 aa)
yisPPutative squalene/phytoene synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the phytoene/squalene synthase family. (274 aa)
yisTConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family. (169 aa)
yjoAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (154 aa)
ykkAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (175 aa)
ohrAPeroxiredoxin; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. (141 aa)
ohrRTranscriptional regulator sensing organic peroxides; Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements. (147 aa)
ylbKPutative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NTE family. (260 aa)
ylbLPutative degradative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (341 aa)
bshCMalate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. (539 aa)
fosBMetallothiol transferase; Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor. (144 aa)
yneACell division inhibitor; Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery (By similarity). (105 aa)
yneBPutative cell division protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process. (217 aa)
ynzCConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12581363, 16267290, 18431750, 19306341; Belongs to the UPF0291 family. (77 aa)
bshBBMalate N-acetylglucosamine deacetylase (second enzyme); Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. (221 aa)
yojFConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (116 aa)
yoyCConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (92 aa)
yojEPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (298 aa)
ctpACarboxy-terminal processing protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme. (466 aa)
bshRProtein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family. (144 aa)
ypdAPutative FAD-dependent disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (324 aa)
yqiWConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0403 family. (145 aa)
yrdAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family. (167 aa)
ytxJConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232. (108 aa)
yuaEConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (162 aa)
tagCPutative polyglycerol phosphate assembly and export protein (teichoic acid biosynthesis); Unknown. Might be involved in poly(glycerol phosphate) teichoic acid biosynthesis. (442 aa)
yxjGPutative methyltetrahydrofolate methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis YxjH. (378 aa)
ppaCInorganic pyrophosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. (309 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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