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yaaI yaaI cypC cypC ybyB ybyB ycdF ycdF ycdG ycdG yczO yczO ydaD ydaD ydaE ydaE ydaG ydaG ydaS ydaS ydaT ydaT gsiB gsiB ydbD ydbD ydjJ ydjJ yflT yflT yflD yflD yflB yflB yflA yflA yfkM yfkM yfkJ yfkJ yfkI yfkI rbn rbn yfkE yfkE yfkD yfkD yfhF yfhF yfhK yfhK yfhL yfhL yfhM yfhM yhdF yhdF yhdN yhdN nhaX nhaX yhxD yhxD yhjQ yhjQ yjzE yjzE yjgB yjgB yjgC yjgC yjgD yjgD yjlB yjlB ykgA ykgA ohrB ohrB ykzN ykzN ykwC ykwC ykzI ykzI ymaE ymaE yoxC yoxC yoxB yoxB yoaA yoaA yocB yocB yocK yocK yqjF yqjF bmrU bmrU yqxL yqxL yqhB yqhB mgsR mgsR ysnF ysnF ytxH ytxH ytxG ytxG dps dps ytaB ytaB yuzH yuzH yugU yugU yvrE yvrE yvgO yvgO yvbG yvbG ywtG ywtG csbD csbD ywmF ywmF ywmE ywmE ywmD ywmD ywjC ywjC ywzA ywzA gspA gspA yxzF yxzF yxxB yxxB csbC csbC yxbG yxbG yxnA yxnA yycD yycD yyzH yyzH yybO yybO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yaaIPutative isochorismatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the isochorismatase family. (181 aa)
cypCFatty acid beta-hydroxylating cytochrome P450; Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide; Belongs to the cytochrome P450 family. (417 aa)
ybyBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (86 aa)
ycdFPutative glucose 1-dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
ycdGPutative oligo-carbohydrate hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (561 aa)
yczOHypothetical protein; Evidence 5: No homology to any previously reported sequences. (54 aa)
ydaDPutative dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (286 aa)
ydaEConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166; Belongs to the D-lyxose ketol-isomerase family. (167 aa)
ydaGPutative general stress protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (140 aa)
ydaSConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (85 aa)
ydaTConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (150 aa)
gsiBGeneral stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation. (123 aa)
ydbDPutative manganese-containing catalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the manganese catalase family. (273 aa)
ydjJPutative membrane associated potassium channel; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (341 aa)
yflTHeat stress induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. (115 aa)
yflDHypothetical protein; Evidence 5: No homology to any previously reported sequences. (45 aa)
yflBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (130 aa)
yflAPutative aminoacid transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (471 aa)
yfkMGeneral stress protein 18; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins. (172 aa)
yfkJProtein-tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance. (156 aa)
yfkIConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210. (106 aa)
rbnPutative ribonuclease BN; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (275 aa)
yfkEPutative H+/Ca2+ antiporter; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium. Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily. (351 aa)
yfkDConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (264 aa)
yfhFPutative nucleotide binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. (303 aa)
yfhKConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (172 aa)
yfhLSdpC immunity factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. (110 aa)
yfhMEpoxide hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the AB hydrolase superfamily. Epoxide hydrolase family. (286 aa)
yhdFPutative NAD(P)-dependent dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (289 aa)
yhdNAldo/keto reductase specific for NADPH; Aldo-keto reductase (AKR) that displays broad substrate specificity in vitro. Is able to reduce the standard AKR substrates DL- glyceraldehyde, D-erythrose, methylglyoxal, p-nitrobenzaldehyde, benzaldehyde and butyraldehyde, in the presence of NADPH. Cannot use NADH as a cosubstrate. Does not act on glucose, 2-pyridine carboxyaldehyde, fructose and xylose. The physiological function of this enzyme is not clear. May play a role in bacterial stress response and/or in detoxification of reactive aldehydes. Belongs to the aldo/keto reductase family. A [...] (331 aa)
nhaXStress response protein, UspA family; Evidence 2b: Function of strongly homologous gene; factor. (166 aa)
yhxDPutative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (299 aa)
yhjQPutative ferredoxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: putative carrier. (108 aa)
yjzEHypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 11976315. (84 aa)
yjgBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1580552. (191 aa)
yjgCPutative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (985 aa)
yjgDConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (186 aa)
yjlBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10704478. (165 aa)
ykgAPutative aminohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the DDAH family. (286 aa)
ohrBOrganic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. (136 aa)
ykzNHypothetical protein; Evidence 5: No homology to any previously reported sequences. (56 aa)
ykwCPutative beta-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HIBADH-related family. (288 aa)
ykzIConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (62 aa)
ymaEPutative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (274 aa)
yoxCConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (101 aa)
yoxBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (256 aa)
yoaAPutative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransferase family. (177 aa)
yocBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (260 aa)
yocKPutative general stress protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (163 aa)
yqjFConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (242 aa)
bmrUPutative lipid kinase BmrU; May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro. (297 aa)
yqxLPutative CorA-type Mg(2+) transporter; Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high. May also mediate uptake of Co(2+). (317 aa)
yqhBPutative membrane associated protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (442 aa)
mgsRTranscriptional regulator of stress; Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress. (126 aa)
ysnFPutative stress response protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype. (273 aa)
ytxHConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16291680, 8733232; To C.plantagineum desiccation-related protein clone PCC3- 06. (151 aa)
ytxGConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232. (140 aa)
dpsDNA-protecting protein, ferritin; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme. (145 aa)
ytaBPutative receptor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc: putative receptor. (155 aa)
yuzHConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (84 aa)
yugUConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0047 family. (132 aa)
yvrEConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the SMP-30/CGR1 family. (292 aa)
yvgOConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11988534. (161 aa)
yvbGPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (211 aa)
ywtGPutative carbohydrate transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (457 aa)
csbDConserved hypothetical protein; Evidence 7: Gene remnant. (62 aa)
ywmFPutative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (159 aa)
ywmEHypothetical protein; Evidence 5: No homology to any previously reported sequences. (53 aa)
ywmDPutative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; To B.subtilis YwmC. (224 aa)
ywjCConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (90 aa)
ywzAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (81 aa)
gspAPutative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (286 aa)
yxzFHypothetical protein; Evidence 5: No homology to any previously reported sequences. (52 aa)
yxxBPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (275 aa)
csbCPutative sugar transporter; Could serve either a nutritional or an osmotic protection function; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (461 aa)
yxbGPutative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (273 aa)
yxnAPutative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (356 aa)
yycDConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (66 aa)
yyzHHypothetical protein; Evidence 5: No homology to any previously reported sequences. (49 aa)
yybOPutative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (435 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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