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licC licC licB licB sacX sacX ywbA ywbA ywbF ywbF sacP sacP rbsA rbsA mdxE mdxE mdxF mdxF mdxG mdxG cycB cycB ganP ganP ganQ ganQ levE levE ybbF ybbF gamP gamP glcU glcU mtlA mtlA mtlF mtlF mtlR mtlR gmuB gmuB gmuC gmuC kdgT kdgT fruA fruA ptsG ptsG bglP bglP nagP nagP treP treP manP manP malP malP glpF glpF manR manR licR licR
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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licCPhosphotransferase system (PTS) lichenan-specific enzyme IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. (452 aa)
licBPhosphotransferase system (PTS) lichenan-specific enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in lichenan transport. (102 aa)
sacXNegative regulator of SacY; Negatively regulates SacY activity by catalyzing its phosphorylation on 'His-99'. Negatively regulates SacY. (459 aa)
ywbAPutative phosphotransferase system enzyme IIC permease component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (444 aa)
ywbFPutative sugar permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (399 aa)
sacPPhosphotransferase system (PTS) sucrose-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport. (461 aa)
rbsARibose ABC transporter (ATP-binding protein); Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (493 aa)
mdxEMaltose/maltodextrin-binding lipoprotein; Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity, but is not involved in its uptake; Belongs to the bacterial solute-binding protein 1 family. (417 aa)
mdxFMaltodextrin ABC transport system (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable). (435 aa)
mdxGMaltodextrin ABC transporter (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable). (278 aa)
cycBCyclodextrin-binding lipoprotein; Binding protein for cyclodextrin; involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha, beta and gamma; Belongs to the bacterial solute-binding protein 1 family. (421 aa)
ganPArabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across the membrane. (418 aa)
ganQArabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across the membrane. (283 aa)
levEPhosphotransferase system (PTS) fructose-specific enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LevDE PTS system is involved in fructose transport. (162 aa)
ybbFPutative PTS system EIIBC component ybbF; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. (455 aa)
gamPPhosphotransferase system (PTS) glucosamine-specific enzyme IICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system may be involved in glucosamine transport. (631 aa)
glcUGlucose uptake protein; Involved in the uptake of glucose. (287 aa)
mtlAPhosphotransferase system (PTS) mannitol-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (478 aa)
mtlFPhosphotransferase system (PTS) mannitol-specific enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport. (143 aa)
mtlRTranscriptional regulator; Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol. (694 aa)
gmuBOligo-alpha-mannoside phosphotransferase system enzyme IIB; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II GmuABC PTS system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose. (103 aa)
gmuCOligo-alpha-mannoside phosphotransferase system enzyme IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II GmuABC PTS system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose. (442 aa)
kdgT2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity). (330 aa)
fruAPhosphotransferase system (PTS) fructose-specific enzyme IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. (635 aa)
ptsGPhosphotransferase system (PTS) glucose-specific enzyme IICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. (699 aa)
bglPPhosphotransferase system (PTS) beta-glucoside-specific enzyme IIBCA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity). (609 aa)
nagPPhosphotransferase system (PTS) N-acetylglucosamine-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport (By similarity). (452 aa)
trePPhosphotransferase system (PTS) trehalose-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in trehalose transport. (470 aa)
manPPhosphotransferase system (PTS) mannose-specific enzyme IIBCA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannose transport. (650 aa)
malPPhosphotransferase system (PTS) maltose-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport. (527 aa)
glpFGlycerol permease; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane; Belongs to the MIP/aquaporin (TC 1.A.8) family. (274 aa)
manRTranscriptional antiterminator; Positively regulates the expression of the mannose operon that consists of three genes, manP, manA, and yjdF, which are responsible for the transport and utilization of mannose. Also activates its own expression. (648 aa)
licRTranscriptional activator of the lichenan operon; Positive regulator of the licABCH operon; Belongs to the transcriptional antiterminator BglG family. (641 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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