node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccdA | hemX | BSU17930 | BSU28160 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K. | 0.589 |
ccdA | resA | BSU17930 | BSU23150 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.994 |
ccdA | resB | BSU17930 | BSU23140 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.995 |
ccdA | resC | BSU17930 | BSU23130 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.991 |
hemX | ccdA | BSU28160 | BSU17930 | Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K. | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | 0.589 |
hemX | resB | BSU28160 | BSU23140 | Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.905 |
hemX | resC | BSU28160 | BSU23130 | Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.762 |
resA | ccdA | BSU23150 | BSU17930 | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | 0.994 |
resA | resB | BSU23150 | BSU23140 | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.996 |
resA | resC | BSU23150 | BSU23130 | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.991 |
resB | ccdA | BSU23140 | BSU17930 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | 0.995 |
resB | hemX | BSU23140 | BSU28160 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K. | 0.905 |
resB | resA | BSU23140 | BSU23150 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.996 |
resB | resC | BSU23140 | BSU23130 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.999 |
resC | ccdA | BSU23130 | BSU17930 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | 0.991 |
resC | hemX | BSU23130 | BSU28160 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K. | 0.762 |
resC | resA | BSU23130 | BSU23150 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.991 |
resC | resB | BSU23130 | BSU23140 | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.999 |