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tcyM tcyM glnP glnP glnM glnM artQ artQ ylmA ylmA thiW thiW dppE dppE oppA oppA ecfA ecfA ecfAB ecfAB yurJ yurJ opuBC opuBC opuCC opuCC yvfS yvfS ganP ganP cycB cycB mdxF mdxF mdxE mdxE tagG tagG msmX msmX yxeN yxeN yydI yydI znuC znuC znuB znuB opuAB opuAB opuAC opuAC yckA yckA tcyB tcyB yfiM yfiM yfiN yfiN mntB mntB mntC mntC mntD mntD tcyL tcyL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tcyMSulfur-containing amino acid ABC transporter (permease); Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine, djenkolate, and S-methylcysteine transport. (235 aa)
glnPGlutamine ABC transporter (permease); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. (218 aa)
glnMGlutamine ABC transporter (permease); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. (216 aa)
artQHigh affinity arginine ABC transporter (permease); Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane. (219 aa)
ylmAPutative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (264 aa)
thiWThiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable). (547 aa)
dppEDipeptide ABC transporter (dipeptide-binding lipoprotein); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation; Belongs to the bacterial solute-binding protein 5 family. (549 aa)
oppAOligopeptide ABC transporter (binding lipoprotein); This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence. (545 aa)
ecfAEnergizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (281 aa)
ecfABEnergizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (276 aa)
yurJPutative multiple sugar ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily. (367 aa)
opuBCCholine ABC transporter (choline-binding lipoprotein); Member of a high affinity multicomponent binding-protein- dependent transport system for choline. (306 aa)
opuCCGlycine betaine/carnitine/choline-binding protein OpuCC; Member of a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine, and choline. Belongs to the OsmX family. (303 aa)
yvfSPutative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (245 aa)
ganPArabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across the membrane. (418 aa)
cycBCyclodextrin-binding lipoprotein; Binding protein for cyclodextrin; involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha, beta and gamma; Belongs to the bacterial solute-binding protein 1 family. (421 aa)
mdxFMaltodextrin ABC transport system (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable). (435 aa)
mdxEMaltose/maltodextrin-binding lipoprotein; Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity, but is not involved in its uptake; Belongs to the bacterial solute-binding protein 1 family. (417 aa)
tagGTeichoic acid precursors permease; Part of the ABC transporter complex TagGH (TC 3.A.1.34.1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-2 integral membrane protein family. (275 aa)
msmXMultiple sugar-binding transporter ATP-binding protein; Part of the ABC transporter complex involved in maltodextrin import (Probable). Is also part of the ABC transporter complex MelEDC- MsmX involved in melibiose, raffinose and stachyose import. Probably responsible for energy coupling to the transport system (Probable). (365 aa)
yxeNPutative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. (224 aa)
yydIABC transporter (ATP-binding protein); Suggested to be part of an ABC transporter complex YydIJ involved in export of the modified peptide YydF (Probable). Responsible for energy coupling to the transport system (By similarity). (209 aa)
znuCZn(II) transporter (ATP-binding protein); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for energy coupling to the transport system (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development. (231 aa)
znuBHigh affinity Zn(II) ABC transporter (permease); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for the translocation of the substrate across the membrane (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development. (280 aa)
opuABGlycine betaine ABC transporter (permease); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane. (282 aa)
opuACGlycine betaine ABC transporter (glycine betaine-binding lipoprotein); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. (293 aa)
yckAPutative ABC transporter (permease); Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily. (226 aa)
tcyBCystine ABC transporter (permease); Part of the ABC transporter complex TcyABC involved in L- cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. (234 aa)
yfiMPutative ABC transporter (permease); Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Part of the ABC transporter complex LnrLMN that probably facilitates linearmycin removal from the membrane. Responsible for the translocation of the substrate across the membrane. Also mediates KinC-dependent biofilm morphology ; Belongs to the ABC-2 integral membrane protein family. (396 aa)
yfiNPutative ABC transporter (permease); Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Part of the ABC transporter complex LnrLMN that probably facilitates linearmycin removal from the membrane. Responsible for the translocation of the substrate across the membrane. Also mediates KinC-dependent biofilm morphology ; Belongs to the ABC-2 integral membrane protein family. (385 aa)
mntBManganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. (250 aa)
mntCManganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. (435 aa)
mntDManganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. (295 aa)
tcyLSulfur-containing amino acid ABC transporter (permease); Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine, djenkolate, and S-methylcysteine transport. (239 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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