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ykuD ykuD yneA yneA yocH yocH cwlS cwlS lytE lytE xkdP xkdP xlyA xlyA ykvP ykvP ykzQ ykzQ yqfZ yqfZ yqbP yqbP safA safA spoVID spoVID ypbE ypbE yaaH yaaH ydhD ydhD lytF lytF xlyB xlyB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ykuDMurein transglycosylase; Probable enzyme that may play an important role in cell wall biology; Belongs to the YkuD family. (164 aa)
yneACell division inhibitor; Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery (By similarity). (105 aa)
yocHPutative exported cell wall-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (287 aa)
cwlSPeptidoglycan hydrolase (cell wall-binding d,l-endopeptidase); Probably functions as a cell separation enzyme in addition to LytE and LytF. (414 aa)
lytECell wall hydrolase; Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth. (334 aa)
xkdPPutative PBSX prophage murein binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. (219 aa)
xlyABacteriophage PBSX N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. (297 aa)
ykvPSpore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. (399 aa)
ykzQPutative peptidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. (75 aa)
yqfZFactor involved in motility; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type ph: phenotype. (99 aa)
yqbPConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (219 aa)
safAMorphogenetic protein associated with SpoVID; Probably involved in the assembly of some coat protein components implicated in both lysozyme resistance and germination. Could be required for the assembly of CotG. Associates with SpoIVD during the early stage of coat assembly. (387 aa)
spoVIDMorphogenetic spore protein (stage VI sporulation); Required for assembly of a normal spore coat. May be a component of the innermost layer of the spore coat that aids in its adherence to the prespore. (575 aa)
ypbEConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855244. (240 aa)
yaaHSpore peptidoglycan hydrolase; N-acetylglucosaminidase involved in cortex peptidoglycan degradation during germination. Cleaves only partially degraded spore peptidoglycans. Recognizes muramic acid delta-lactam residues specific to spore peptidoglycans. (427 aa)
ydhDSpore cortex lytic enzyme; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process; Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. (420 aa)
lytFgamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin); Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan. LytF is necessary and sufficient for vegetative daughter cell separation, and also seems to play a role in cell autolysis. (488 aa)
xlyBN-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. (317 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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