STRINGSTRING
ganR ganR med med degA degA yhjM yhjM exuR exuR ykvZ ykvZ kdgR kdgR ccpA ccpA msmR msmR nupN nupN araR araR mdxR mdxR rbsR rbsR rbsB rbsB ccpB ccpB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ganRTranscriptional regulator (LacI family); Negatively regulates expression of ganA. (330 aa)
medPositive regulator of comK; Positive activator of the comK gene; Belongs to the BMP lipoprotein family. (317 aa)
degATranscriptional regulator (LacI family); Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease. (337 aa)
yhjMTranscriptional regulator of the ntd operon; Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription. (329 aa)
exuRTranscriptional regulator (LacI family); Transcriptional repressor for the exu locus which is required for galacturonate utilization. (333 aa)
ykvZPutative transcriptional regulator (LacI family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator. (321 aa)
kdgRKdg operon transcriptional regulator (LacI family); Transcriptional repressor of the kdgRKAT and kduID operons for pectin utilization. (339 aa)
ccpATranscriptional regulator (Lacl family); Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. Interacts with either P- Ser-HPr or P-Ser-Crh, leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons. (334 aa)
msmRTranscriptional regulator (LacI family); Represses the melibiose operon melREDCA in the absence of melibiose or raffinose. Binds to two binding sites at the promoter region of the operon. (344 aa)
nupNLipoprotein involved in guanosine transport; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein. (359 aa)
araRTranscriptional repressor of the ara regulon (LacI family); Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter. (362 aa)
mdxRTranscriptional activator of the maltodextrin operon (LacI family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type pr: putative regulator. (316 aa)
rbsRTranscriptional regulator (LacI family); Transcriptional repressor for the ribose rbsDACBK operon. (326 aa)
rbsBRibose ABC transporter (ribose-binding lipoprotein); Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose. (305 aa)
ccpBTranscriptional repressor of carbon supply (LacI family); Transcriptional regulator involved in catabolite repression of several operons. (311 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.